Study in vitro anti-microbial activity of Ricinus communis extract.
Journal name: World Journal of Pharmaceutical Research
Original article title: To study the in vitro anti-microbial activity of ethanolic extract of stems and leaves of the plant ricinus communis. (family- euphorbiaceae)
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Mahbub Alom and Proff. Dr Gouranga Das
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: To study the in vitro anti-microbial activity of ethanolic extract of stems and leaves of the plant ricinus communis. (family- euphorbiaceae)
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr201812-12606
Copyright (license): WJPR: All rights reserved
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Summary of article contents:
Introduction
Ricinus communis, commonly known as the castor oil plant, is a perennial flowering plant belonging to the Euphorbiaceae family. Recognized for its potential medicinal properties, the various parts of this plant, including the leaves, stems, and seeds, possess antimicrobial activities. This study focuses on evaluating the antimicrobial effects of ethanolic extracts from Ricinus communis, comparing their efficacy to the standard antibiotic Azithromycin through the disc diffusion method. The study aims to highlight the potential of this plant as a natural alternative to synthetic antimicrobials, particularly in light of rising antimicrobial resistance issues.
Importance of Traditional Medicine
The global reliance on traditional medicine remains significant, with approximately 80% of the population depending on herbal remedies for treatment, as per WHO reports. This traditional therapeutic approach is increasingly vital due to the growing challenges posed by antibiotic resistance. The excessive use of conventional antibiotics has resulted in microorganisms developing resistance, making it essential to explore alternative antimicrobial sources. Ricinus communis acts as a pivotal example of a traditional medicine that possesses significant antimicrobial properties, affirming its relevance in modern therapeutic practices amid the increasing prevalence of drug-resistant pathogens.
Extraction and Antimicrobial Activity
In this study, the antimicrobial activity of Ricinus communis was assessed by preparing various extracts using petroleum ether, chloroform, and ethanol. The dried powdered plant material underwent Soxhlet extraction for a prolonged duration, yielding a semi-solid mass stored for further analysis. The antibacterial potential was evaluated using the agar well diffusion method, where it was noted that the ethanolic extract exhibited notable antibacterial characteristics against different bacteria, including Staphylococcus aureus and Escherichia coli. The findings indicated a significant zone of inhibition, showcasing the extract's effectiveness compared to the standard antibiotic.
Phytochemical Screening
The study also emphasized the phytochemical screening of the Ricinus communis extracts, which affirmed the presence of various bioactive compounds known for their antibacterial properties. The results indicated that the plant extracts exhibited substantial antimicrobial activity across several bacterial strains, supporting the notion that Ricinus communis is a potent antimicrobial agent. This underscores the potential of the plant not only for medicinal use but also for formulating new antimicrobial drugs to combat resistant strains effectively.
Conclusion
The research conclusively establishes the significant antimicrobial activity of Ricinus communis, highlighting its potential as a valuable resource in developing new antibacterial compounds. Owing to the increasing challenges of antimicrobial resistance, the study suggests further exploration and utilization of plant extracts in creating innovative and effective treatments. The promising results encourage the pursuit of Ricinus communis in pharmacological applications, paving the way to a new frontier in the development of natural antimicrobials and emphasizing the importance of integrating traditional knowledge with modern medicine.
FAQ section (important questions/answers):
What is Ricinus communis and its significance?
Ricinus communis, known as the castor oil plant, is a flowering plant in the Euphorbiaceae family, valued for its antimicrobial properties and used in traditional medicine.
What methods were used to extract Ricinus communis?
The study used Soxhlet extraction with petroleum ether, chloroform, and ethanol for 72 hours to obtain the extracts of Ricinus communis.
How was the antimicrobial activity measured in the study?
Antimicrobial activity was assessed using the agar disc diffusion method, measuring the zone of inhibition of the extracts against specific bacteria.
Which bacteria were tested for antimicrobial activity?
The study evaluated the effectiveness of Ricinus communis extracts against Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli.
What were the results of the antimicrobial testing?
The ethanolic extracts of Ricinus communis demonstrated significant antibacterial activity, especially with inhibition zones against tested microbes, indicating its potential as an antimicrobial agent.
What is the study's conclusion regarding Ricinus communis?
The study concluded that Ricinus communis extracts possess considerable antimicrobial activity, suggesting future potential for developing new antimicrobial drugs to combat resistant pathogens.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Study in vitro anti-microbial activity of Ricinus communis extract.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Activity:
Activity refers to the observable effects or responses that a substance or organism exhibits when interacting with others. In this study, it specifically relates to the antimicrobial actions of Ricinus communis extracts against various pathogenic microorganisms, highlighting its importance in developing natural alternatives to synthetic antimicrobial agents.
2) Ricinus communis:
Ricinus communis, commonly known as the castor oil plant, is a significant herbaceous plant in the Euphorbiaceae family. This species is investigated for its valuable medicinal properties, particularly its antimicrobial activity, making it a focus for research on natural therapies for treating infectious diseases.
3) Drug:
A drug is any substance that can alter physiological functions in the body, typically prescribed to treat diseases. In the context of this study, it refers to potential new antimicrobial agents derived from Ricinus communis, which could serve as alternatives to synthesized pharmaceuticals, especially in combating antibiotic resistance.
4) Disease:
Diseases refer to health conditions that disrupt normal bodily functions. The focus of this research on diseases caused by microbes underscores the urgency of identifying effective treatments from natural sources like Ricinus communis to combat the increasing incidence of drug-resistant infections.
5) Science (Scientific):
Science is the systematic study of the natural world through observation and experimentation. This research on the antimicrobial effects of Ricinus communis emulates the scientific principle of investigating plant-based solutions to health issues, thereby enriching the scientific understanding of traditional medicine.
6) Family:
In biological classification, family is a rank that groups related organisms. The Euphorbiaceae family includes Ricinus communis among other species, emphasizing its evolutionary relationships. Understanding the family context aids in recognizing the broader implications and uses of related plants in medicine.
7) Study (Studying):
Study refers to the detailed investigation and analysis of a subject. This research explores the antimicrobial properties of Ricinus communis, providing scientific evidence for its potential therapeutic uses. The study contributes to the body of knowledge needed for developing novel antimicrobial agents derived from plants.
8) Antibiotic (Antibacterial):
Anti-bacterial emphasizes the capacity to combat or inhibit bacteria's growth. The study focuses extensively on evaluating the anti-bacterial properties of Ricinus communis, providing valuable data to enhance the development of new antimicrobial agents, essential in the fight against resistant bacterial strains.
9) Soil:
Soil is a complex ecosystem that supports plant growth and affects their development and medicinal potential. The study notes the specific soil conditions conducive to growing Ricinus communis, emphasizing the importance of environmental factors in the extraction and efficacy of plant-derived medicinal compounds.
10) Medicine:
Medicines encompass substances used to prevent, diagnose, or treat diseases. This study contributes to the field by exploring how extracts from Ricinus communis can serve as effective herbal medicines, promoting the need for research into plant-derived therapeutic options in contemporary healthcare.
11) Species:
Species is the basic unit of biological classification, representing a group of organisms capable of interbreeding. Ricinus communis is the sole species of its genus, making its unique properties, including antimicrobial activity, vital for both scientific and medical research within the Euphorbiaceae family.
12) Castor:
Castor refers to the castor bean plant, Ricinus communis, known for its seeds, which produce castor oil. The term is significant in the study as it establishes the common name and recognition of the plant's potential therapeutic benefits, including its antimicrobial properties.
13) India:
India is a country rich in traditional medicine practices, where plants like Ricinus communis are often used for healing. The study acknowledges its cultural significance and the reliance on indigenous knowledge, blending it with modern scientific approaches to explore antimicrobial activities.
14) Water:
Water is essential for all living organisms and plays a crucial role in plant health and extract preparation. In the study, the washing and preparation processes highlight the importance of water in obtaining pure and effective extracts from Ricinus communis for antimicrobial testing.
15) Aureus:
Aureus refers to Staphylococcus aureus, a common bacterium studied for its pathogenicity and resistance to antibiotics. By examining the antibacterial effects of Ricinus communis on this bacterium, the study contributes to understanding potential treatments against one of the significant bacterial threats in medicine.
16) Powder:
Powder represents the form in which dried plant material is processed for extraction. In this study, Ricinus communis was ground into powder to facilitate effective solvent extraction, underlining the importance of preparation methods in enhancing the delivery of medicinal properties in research.
17) Indian:
Indian in this context relates to the cultural and traditional aspects of medicine and herbal usage in India. The investigation into Ricinus communis not only honors this heritage but also aims at validating the effectiveness of these plant-derived treatments through scientific research.
18) Tree:
Trees indicate the growth form of woody plants, including those in the Euphorbiaceae family. Recognizing Ricinus communis as a tree emphasizes its ecological role and medicinal usage, contributing to the understanding of how plant morphology relates to their therapeutic potential.
19) Rich (Rch):
Rich indicates the abundance of certain compounds or properties present in a substance. The term is used in this study to describe how Ricinus communis contains a multitude of antimicrobial agents, reaffirming its potential as a source for developing effective natural antimicrobial therapies.
20) Phytochemical:
Phytochemical refers to the bioactive compounds derived from plants. The study on Ricinus communis stresses the significance of identifying phytochemicals responsible for its antimicrobial activity, carrying implications for drug discovery and development, particularly in the realm of natural products.
21) Inflammation:
Inflammation is a biological response to tissue damage or infection, often leading to symptoms that can be treated with medicinal compounds. Ricinus communis has historical uses in alleviating inflammation, making its study relevant for understanding its broader therapeutic potential against inflammatory disorders.
22) Calculation:
Calculation in this study refers to the mathematical processes used to determine the yield of plant extracts. Understanding extraction efficiency is crucial for conducting further research and confirming the effectiveness of the antimicrobial properties of the derived compounds.
23) Ayurveda (Ayus-veda):
Ayurveda is an ancient Indian system of medicine emphasizing holistic healing through natural substances. The relevance of Ayurvedic practices in the context of Ricinus communis reflects the historical application and knowledge of plants for medicinal purposes, bridging traditional medicine with modern research.
24) Mineral:
Minerals are inorganic elements essential for various bodily functions and are often present in plant systems. The study may indirectly reference the importance of minerals found in the soil for the growth of Ricinus communis, contributing to its medicinal efficacy through the uptake of these vital nutrients.
25) Brahma:
Brahma here acknowledges U.N. Brahma Chari, a referenced author, contributing to the context of the study. Citing established research helps emphasize the continuity of knowledge in the scientific community and the relevance of integrating historical perspectives into modern studies.
26) Nature:
Nature represents the natural world, encompassing plants like Ricinus communis that have intrinsic value in promoting health. This study underscores the parallel between understanding natural remedies and traditional practices and the necessity of scientifically validating these resources for today's medical challenges.
27) Medium:
Medium, in the context of this research, refers to the growth environment or culture medium used to cultivate microorganisms. The choice of medium is crucial for accurately testing the antibacterial efficacy of Ricinus communis extracts, thus influencing the study’s experimental outcomes.
28) Botany:
Botany is the scientific study of plants, which includes understanding their structures, properties, and potential uses. This research on Ricinus communis relies on botanical knowledge to inform extraction methods and validate the plant’s medicinal qualities, melding botanical science with pharmacological applications.
29) Table:
Table refers to the organized presentation of data in the study, particularly showcasing the results of antibacterial testing. Using tables helps visualize and summarize findings effectively, facilitating clearer communication of experimental outcomes between researchers and practitioners.
30) Doubt:
Doubt signifies uncertainty, particularly in scientific contexts where results must be replicated and verified. The study addresses potential doubts regarding the efficacy of Ricinus communis, aiming to provide evidence-based conclusions that could influence its acceptance and use as an antimicrobial agent.
31) Carin (Cari):
Chari refers to U.N. Brahma Chari, as mentioned previously, emphasizing authorship in the cited references. The acknowledgment of various researchers in studies lends credibility and depth, illustrating the collaborative nature of scientific inquiry and the ongoing search for knowledge.
32) Genu:
Genu refers to a unique biological classification term, potentially related to 'genus'. Its relevance in the context of Ricinus communis lies in the emphasis on classification and understanding the significance of genetic relationships among plant species in medicinal research.
33) Wall:
Wall refers to the cellular structure that provides support to plant cells. Understanding the composition and characteristics of cell walls in Ricinus communis can inform the extraction methods and treatment of obtained compounds, thus affecting their medicinal efficacy.
34) Shand (Sand):
Sand pertains to the soil composition favorable for cultivating plants like Ricinus communis. The study’s focus on the plant’s preferred soil types highlights the importance of environmental conditions for the growth and subsequent extraction of effective medicinal compounds.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Study in vitro anti-microbial activity of Ricinus communis extract.’. Further sources in the context of Science might help you critically compare this page with similair documents:
Ricinus communis, Traditional medicine, Phytochemical screening, Zone of inhibition, Anti-microbial activity, Antimicrobial Resistance, Euphorbiaceae family, Agar disc diffusion method, Soxhlet extraction, Clinical use, Plant Extract, Inflammatory disease, Antimicrobial compound, Fixed oil, Dried powdered, Antibacterial components.