Efficacy of karanj beejadi lep in vicharchika w.r.t.eczema
Journal name: World Journal of Pharmaceutical Research
Original article title: Efficacy of karanj beejadi lep in vicharchika w.r.t.eczema
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Dr. Prakash Mane, Dr. Dahake S. J., Dr. Jyotsna Gulhane, Dr. P. B. Jondhale, Dr. Surekha Atram, Dr. Mangesh Udmale, Dr. Sachin Rohani and Dr. Sanjay Babar
World Journal of Pharmaceutical Research:
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Full text available for: Efficacy of karanj beejadi lep in vicharchika w.r.t.eczema
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr201815-13022
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Summary of article contents:
Introduction
This study explores the efficacy of Karanj Beejadi Lep in treating Vicharchika, a condition linked to eczema. The research highlights that skin disorders often stem from irregular dietary practices and lifestyle factors that disrupt the body’s balance or agni. Vicharchika, classified among skin diseases in Ayurveda, is associated with symptoms such as itching, papules, and skin discoloration. Although modern dermatology has made significant advancements, the treatment of eczema remains largely symptomatic. The study posits that Ayurvedic approaches, such as the topical application of Karanj Beejadi Lep, may provide holistic and effective relief.
Efficacy of Ayurvedic Treatment
The study was structured as a single-blind observational clinical trial involving 30 patients diagnosed with Vicharchika based on Ayurvedic criteria. The main objective was to evaluate the effects of Karanj Beejadi Lep in combination with Gomutra on the symptoms associated with Vicharchika, including pruritus, papules, and hyperpigmentation. The treatment showed substantial improvement over a 30-day period, with notable reductions in the severity of symptoms as measured by pre- and post-treatment scoring.
Symptom Improvement through Treatment
The results demonstrated significant improvement across several symptoms. For pruritus, the initial mean score of 3.50 was reduced to 0.42 by day 30, indicating an 86% improvement. Similar trends were observed for papules and hyperpigmentation, where reductions of 86.40% and 63.91% were noted, respectively. The methodical assessment utilized standard scoring techniques and statistical analyses, confirming the treatment's effectiveness and significant impact on patients' quality of life.
Safety and Preparation of Treatment
Karanj Beejadi Lep was prepared using a blend of various Ayurvedic herbs, which are believed to possess properties useful for managing skin conditions. The application process involved a topical administration that allows the active ingredients to penetrate the skin effectively. The safety profile of the treatment was notably positive; no adverse effects were recorded throughout the trial period, reinforcing the potential of Ayurvedic remedies in dermatological care.
Conclusion
In conclusion, the study establishes Karanj Beejadi Lep as a promising treatment for Vicharchika, showing significant efficacy in alleviating symptoms. The findings encourage further investigation into Ayurvedic treatments for skin disorders and suggest the need for larger, multicenter clinical trials to validate these results. Karanj Beejadi Lep showcases the potential of traditional medicine in providing safe, holistic treatment options for eczema and related skin conditions.
FAQ section (important questions/answers):
What is Vicharchika in Ayurvedic medicine?
Vicharchika is an Ayurvedic term for a skin disorder, closely related to eczema, characterized by symptoms like itching, papules, hyperpigmentation, and discharge. It is categorized under Kushtha, indicating a skin disease originating from imbalances in doshas.
What is Karanj Beejadi Lep used for?
Karanj Beejadi Lep is a topical Ayurvedic formulation used to treat Vicharchika. Its active ingredients are believed to help alleviate symptoms such as itching, papules, hyperpigmentation, and dryness associated with skin conditions like eczema.
How was the clinical trial structured?
The clinical trial involved 30 randomly selected patients with Vicharchika. It was a single blind observational study, with assessments conducted at regular intervals over 30 days to monitor improvements in symptoms following treatment with Karanj Beejadi Lep.
What were the study's key findings on symptoms improvement?
The study reported significant reductions in symptoms: itching improved by 86%, papules by 86%, hyperpigmentation by 63.91%, and dryness by 86%, indicating that the treatment effectively managed the signs of Vicharchika.
What were the inclusion criteria for the participants?
Participants were aged between 15-70 years, diagnosed with Vicharchika based on Ayurvedic symptomatology, and displaying specific symptoms. Those with severe systemic conditions and secondary infections were excluded from the study.
What future research is suggested by the authors?
The authors recommend further multicenter clinical studies with larger sample sizes to validate the efficacy of Karanj Beejadi Lep in treating Vicharchika and to establish its therapeutic potential in a broader context.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Efficacy of karanj beejadi lep in vicharchika w.r.t.eczema”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Study (Studying):
The word 'Study' denotes a structured investigation aimed at evaluating the efficacy of Karanj Beejadi Lep in treating Vicharchika, or eczema. Conducting a clinical study allows researchers to analyze data, assess therapeutic outcomes, and draw conclusions on treatment effectiveness, thereby contributing to evidence-based practice and academic discourse in Ayurveda.
2) Drug:
In this context, 'Drug' refers specifically to Karanj Beejadi Lep, an Ayurvedic formulation used topically to manage symptoms of Vicharchika. Understanding its pharmacological properties, such as effects on skin lesions, itching, and inflammation, is essential in determining its place in Ayurvedic therapy and its potential as an alternative treatment for eczema.
3) Patil:
'Patil' in the text likely refers to Dr. D.Y. Patil Ayurved College, where the study took place. This institution is significant for training in Ayurvedic medicine and research, fostering advancements in traditional healing practices, and providing educational resources that bridge ancient knowledge with modern medical science.
4) Pune:
'Pune' is the city where the study was conducted and is renowned as an educational hub in India. The city's medical institutions, particularly in Ayurvedic medicine, contribute significantly to research and healthcare, facilitating advances in traditional treatments and their integration into broader medical practices.
5) Gomutra (Go-mutra):
'Gomutra' refers to cow urine, which holds a special place in Ayurvedic treatments due to its believed therapeutic benefits. In the context of the study, Gomutra serves as an ingredient in Karanj Beejadi Lep, enhancing its effectiveness by aiding absorption through the skin and possessing properties considered beneficial for the treatment of skin disorders.
6) Shyava (Syava):
The term 'Shyava' describes a symptom associated with Vicharchika, pertaining to hyperpigmentation or discoloration of the skin. Understanding this manifestation is crucial as it informs diagnosis and treatment strategies in Ayurveda, helping practitioners recognize the links between symptoms and underlying pathological processes in skin diseases.
7) Kandu (Kamdu):
'Kandu' is a key symptom in Vicharchika that refers to severe itching. This manifestation is particularly distressing for patients and serves as a crucial parameter for evaluating treatment outcomes in the study. Identifying and alleviating itching is essential for improving patients' quality of life and overall treatment satisfaction.
8) Sign:
'Sign' refers to observable indicators of a disease condition, which in this context pertains to physical symptoms of Vicharchika. Identifying signs helps clinicians assess the severity of the condition, track treatment progress, and improve diagnosis accuracy, fostering holistic management through careful monitoring of patient responses.
9) Pain:
'Pain' is another critical symptom of Vicharchika that affects patients' daily functioning. The study measured reductions in pain levels to assess the treatment's effectiveness. Understanding pain management within Ayurvedic contexts underscores the need for integrative approaches in treating chronic skin conditions like eczema.
10) Disease:
'Disease' in this context pertains to Vicharchika, which is classified as a type of eczema. Acknowledging its classification as a disease within Ayurvedic texts provides insights into its etiology, treatment modalities, and the historical evolution of herbal remedies aimed at alleviating such skin disorders.
11) Shrava (Srava):
'Srava' refers to the oozing or discharge characteristic of Vicharchika. Monitoring the degree of discharge is essential, as it signifies the progression of the disease and effectiveness of the treatment. Managing Srava is particularly important in preventing secondary infections and promoting skin healing.
12) Suffering:
'Suffering' encompasses the physical and emotional distress experienced by patients with Vicharchika. Addressing suffering holistically in Ayurveda emphasizes the need for both symptom relief and improving patients' well-being, demonstrating the alignment of Ayurvedic principles with contemporary priorities in patient-centered care.
13) Kushtha (Kustha):
'Kustha' encompasses a range of skin diseases in Ayurveda, including Vicharchika. This classification is vital for understanding the symptoms and therapeutic approaches specific to skin conditions, allowing practitioners to integrate Ayurvedic principles and treatments effectively in managing skin disorders.
14) Science (Scientific):
'Science' denotes the systematic study of phenomena, particularly in relation to the efficacy of Ayurvedic treatments. The integration of science into traditional practices exemplifies the ongoing quest for validation of alternative therapies through research methodologies, thereby enhancing credibility and acceptance within the broader medical community.
15) Pidika:
'Pidika' refers to the papules or small bumps on the skin associated with Vicharchika. Recognizing this specific symptom is essential for diagnosis and treatment assessment. Effective management of Pidika is vital for improving the skin's appearance and alleviating patient discomfort during the healing process.
16) Pitta:
'Pitta' is one of the three doshas in Ayurveda, associated with the qualities of heat and transformation. Its role in skin diseases, particularly Vicharchika, is significant, as an imbalance may contribute to symptoms experienced. Understanding doshic interactions helps guide effective treatment strategies within Ayurvedic practices.
17) Ruja:
'Ruja' denotes pain, a common symptom faced by patients with Vicharchika. Analyzing pain relief as a treatment outcome becomes essential in clinical studies, as it directly impacts patients' overall satisfaction and quality of life, underscoring the importance of holistic approaches in managing chronic skin conditions.
18) Lepa:
'Lepa' refers to the topical application of herbal preparations, a traditional Ayurvedic practice. In the study, Karanj Beejadi Lep was investigated for its effects on Vicharchika. The efficacy of such applications highlights the importance of localized treatments and their ability to provide symptomatic relief while addressing the disease's root causes.
19) Bhaishajya (Bhaisajya):
'Bhaishajya' means medicine or treatment in Ayurveda. This term is critical in understanding the concepts of healing and therapy within the system. It encapsulates the various classifications of medicinal formulations, their preparation, and application, promoting a holistic approach to healthcare through natural remedies.
20) Ayurveda (Ayus-veda):
'Ayurveda' denotes the traditional system of medicine originating from India, emphasizing balance in bodily systems and natural healing. Its significance in contemporary healthcare lies in its holistic approach, incorporating diet, lifestyle, and herbal medicine to treat diseases, including skin disorders like Vicharchika, and fostering patient well-being.
21) Rukshata (Ruksata):
'Rukshata' signifies dryness, which is a notable symptom of Vicharchika. The management of Rukshata is imperative in treating skin conditions to restore moisture and skin health. Addressing this symptom reflects the comprehensive Ayurvedic understanding of skin pathology and the importance of hydrating therapies in treatment modalities.
22) Kshudra (Ksudra):
'Kshudra' describes minor ailments or diseases in Ayurvedic texts. Understanding this classification enables practitioners to gauge the severity of Vicharchika, informing treatment approaches. By distinguishing Kshudra rogas from more serious conditions, practitioners can tailor interventions and optimize patient outcomes within the Ayurvedic framework.
23) Kalpana:
'Kalpana' in Ayurvedic contexts refers to the preparation and formulation of medicines. This term is essential for understanding how herbal remedies are tailored to treat specific conditions effectively. It highlights the artistry involved in creating effective treatments and the importance of proper formulation in achieving therapeutic results.
24) Itching:
'Itching' is a significant discomfort experienced by patients suffering from Vicharchika. Effective management of itching is a primary goal in treatment, indicating the need for formulations that address this symptom specifically. Relief from itching contributes to improved patient satisfaction and overall quality of life.
25) Shotha (Sotha):
'Shotha' signifies swelling or thickness of the skin, which is a common feature in Vicharchika. Recognizing and alleviating Shotha enhances patient comfort and is a critical factor in assessing treatment effectiveness. Managing swelling is vital for restoring normal skin texture and function.
26) Kapha:
'Kapha' refers to one of the three doshas in Ayurveda, characterized by qualities of stability, moisture, and coldness. Its imbalance is often implicated in skin conditions. Understanding Kapha's role in Vicharchika helps clinicians tailor treatments that harmonize this dosha, promoting balance and skin health.
27) Table:
'Table' in this context refers to the data presentation of the study's findings. Utilizing tables allows for concise visual summaries of results, comparisons, and statistical analyses. This structure facilitates easier interpretation of complex data, enhancing transparency and knowledge dissemination in academic and clinical settings.
28) Blood:
'Blood' is referenced in the context of routine hematological investigations to evaluate systemic health. Such tests are crucial for ruling out underlying conditions and ensuring patients are fit for treatment. Monitoring blood parameters provides insights into overall health status and informs clinical decisions in Ayurvedic practices.
29) Vata:
'Vata' is one of the three doshas in Ayurveda, characterized by qualities of dryness, movement, and lightness. Its role in skin diseases often necessitates balancing treatments. Understanding Vata's influence on Vicharchika assists practitioners in crafting individualized therapies that promote overall skin health and well-being.
30) Life:
'Life' signifies the holistic perspective in Ayurveda, emphasizing the interconnection of body, mind, and spirit. This concept guides practitioners in addressing not only physical symptoms of Vicharchika but also the emotional and psychological aspects, aiming for comprehensive well-being and patient-centered care.
31) Saussurea lappa:
'Saussurea lappa,' an ingredient in Karanj Beejadi Lep, has traditional uses in treating skin conditions. Its efficacy stems from its potential anti-inflammatory and antiseptic properties. Including this herb in the formulation highlights the importance of synergistic combinations in achieving therapeutic goals in Ayurvedic medicine.
32) Kshudraroga (Kshudra-roga, Ksudraroga):
'Kshudra-roga' refers to minor diseases within the Ayurvedic context. Classifying Vicharchika as Kshudra-roga indicates its perceived severity and informs treatment approaches that are appropriate for non-severe skin ailments, guiding practitioners in providing effective and tailored interventions.
33) Maharashtra (Maharastra, Maha-rashtra):
'Maharashtra' is the state in India where the study took place, home to Ayurvedic institutions. The region's cultural and historical context contributes to the richness of Ayurvedic heritage, supporting research and treatment practices in dermatology and the integration of traditional and modern medicine.
34) Observation:
'Observation' emphasizes the systematic assessment of clinical signs and patient responses during the study. This crucial component ensures that treatment outcomes are documented accurately, guiding future research and enhancing clinical expertise within the realm of Ayurvedic medicine and skin disorder management.
35) Vatapitta (Vata-pitta):
'Vata-pitta' denotes a specific doshic imbalance significant in skin conditions. Understanding this dual imbalance helps practitioners formulate targeted treatments that address symptoms while restoring balance to these doshas, essential for promoting healing and overall skin health in conditions like Vicharchika.
36) Tridoshaja (Tridosaja):
'Tridoshaja' refers to conditions arising from imbalances of the three doshas: Vata, Pitta, and Kapha. Recognizing Vicharchika as Tridoshaja emphasizes comprehensive treatment strategies that address the multifactorial nature of skin diseases, reflecting Ayurveda's holistic approach to health and wellness.
37) Discussion:
'Discussion' refers to the examination and interpretation of study findings, providing insights into the implications of the results. This section is vital for contextualizing research within existing literature, evaluating the efficacy of interventions, and guiding further investigation in Ayurvedic dermatology.
38) Developing:
'Developing' pertains to the context of developing countries where skin diseases like eczema are prevalent due to lifestyle and environmental factors. Recognizing these settings emphasizes the need for accessible and culturally relevant treatment options, reinforcing Ayurveda's potential contribution to holistic health solutions.
39) Antibiotic (Antibacterial):
'Antibiotic' refers to modern medicine's approach to treating bacterial infections associated with skin lesions. Understanding the role of antibiotics in managing secondary infections highlights the importance of integrating traditional Ayurvedic remedies with modern pharmaceuticals, fostering comprehensive treatment strategies for skin disorders.
40) Kandughna (Kandu-ghna):
'Kandughna' describes properties or actions that alleviate itching, a primary concern in treating Vicharchika. Identifying treatments with Kandughna effects underscores the necessity of symptom-targeted therapies in Ayurveda, where addressing discomfort contributes significantly to overall patient satisfaction and a positive therapeutic experience.
41) Tridosha (Tridosa, Tri-dosha):
'Tridosha' conceptually represents the three fundamental energies in Ayurveda: Vata, Pitta, and Kapha. Understanding their interplay is essential for diagnosing and treating conditions like Vicharchika, guiding practitioners to tailor interventions that restore balance and promote health across the whole person.
42) Pradhana:
'Pradhana' refers to the dominant factor in a particular condition within the Ayurvedic framework. Recognizing which dosha may be Pradhana in Vicharchika guides the formulation of personalized treatment plans that target the root causes of symptoms and promote effective healing.
43) Krimighna (Krmighna, Krimi-ghna):
'Krmighna' denotes properties or actions that combat parasitic infections, which may complicate skin conditions like Vicharchika. Highlighting Krmighna effects emphasizes the need for comprehensive treatments within Ayurveda that address both the primary ailment and any secondary infections that may arise.
44) Activity:
'Activity' refers to the physiological and biological actions of drugs and treatments. Understanding the mechanisms of action behind Karanj Beejadi Lep allows practitioners to appreciate how specific components contribute to alleviating symptoms of Vicharchika, guiding effective application in clinical settings.
45) Ruksha (Ruksa):
'Ruksha' signifies dryness and its implications for skin health in the context of Vicharchika. Acknowledging Ruksha as a symptom underscores the need for remedies that restore moisture and provide emollient properties, reflecting the holistic approach of Ayurveda in treating skin ailments.
46) Pidaka:
'Pidaka' describes superficial skin eruptions such as blisters or papules. Recognizing this symptom aids in accurately diagnosing Vicharchika and monitoring treatment effectiveness, ensuring a comprehensive approach to managing skin conditions through targeted therapies and clinical evaluation.
47) Cancer:
'Cancer' is referenced as a condition that was excluded from the study participants. Its mention underscores the necessity of identifying comorbidities in research to ensure participant safety and the integrity of study results, highlighting thorough clinical protocols and ethical considerations in Ayurvedic research.
48) Karma (Karman):
'Karma' in this context refers to the action or effect of Ayurvedic treatments. This term emphasizes the intention and holistic philosophy that guide each treatment decision, aligning therapeutic actions with patients' individual needs for optimal healing and symptom management.
49) Laghu:
'Laghu' denotes lightness, a property associated with certain Ayurvedic substances. Recognizing Laghu properties in herbal formulations emphasizes the consideration of dosage and effects on the body, influencing how treatments are perceived and applied in managing patient conditions like Vicharchika.
50) Tikta:
'Tikta' signifies bitterness, a taste associated with the therapeutic effects of some Ayurvedic herbs. Understanding the role of Tikta in formulations highlights the importance of taste in Ayurvedic medicine, guiding the selection of ingredients that promote healing and balance in specific conditions.
51) Ushna (Usna):
'Ushna' refers to the warming qualities of certain Ayurvedic remedies. In the context of Vicharchika, Ushna properties may play a role in alleviating symptoms by counteracting coldness or stagnation, demonstrating the intricate balance of thermal properties in therapeutic applications of plant-based medicines.
52) Virya:
'Virya' encapsulates the inherent potency of Ayurvedic substances to bring about physiological changes. Recognizing the Virya of ingredients like the Karanj Beejadi Lep can help practitioners assess the potential efficacy of treatments for conditions such as Vicharchika based on their energetic properties.
53) Field:
'Field' refers to the domain of dermatological study where Ayurvedic principles are applied to manage skin conditions. This emphasizes the integration of traditional healing practices with clinical research, enhancing understanding of skin diseases and enriching the medical discourse surrounding their treatment.
54) Sweating (Sweat):
'Sweat' refers to the excretory function of the skin, which can be influenced by skin diseases like Vicharchika. Acknowledging the role of sweat in skin health prompts holistic approaches to treatment, focusing not only on symptoms but also on underlying physiological processes affecting the skin.
55) Roga:
'Roga' means disease in Sanskrit and provides a foundational term for discussing various health conditions in Ayurvedic texts. Distinguishing Roga types guides practitioners in understanding the specific characteristics and appropriate interventions required for ailments like Vicharchika, enhancing effective diagnosis and treatment.
56) Agni:
'Agni' refers to digestive fire in Ayurveda, which is central to maintaining overall health. Recognizing its role in skin diseases suggests that imbalances in Agni may contribute to conditions such as Vicharchika, thus guiding dietary and lifestyle recommendations as part of the treatment strategy.
57) Katu:
'Katu' signifies spiciness or pungency, qualities of certain herbs that can stimulate digestion and metabolism. Acknowledging Katu properties in Ayurvedic formulations aids in selecting ingredients to enhance treatment efficacy, maximizing therapeutic actions targeted at relieving symptoms of skin conditions.
58) Guna:
'Guna' denotes the inherent qualities or attributes of substances in Ayurveda. Understanding Guna assists practitioners in determining the suitable characteristics of herbs or formulations to treat specific conditions, ensuring that treatments align with patients' unique needs and promote optimal healing.
59) Raji:
'Raji' refers to thickening of the skin, a symptom associated with Vicharchika. Recognizing this condition allows practitioners to tailor treatments aimed at promoting skin healing and restoring normal texture, emphasizing the importance of comprehensive symptom management within Ayurvedic therapy.
60) Tora:
'Tora' is an Ayurveda herb known for its properties believed beneficial in skin treatment. Recognizing Tora's role in formulations allows researchers to study its effectiveness in addressing skin conditions, encouraging further exploration of traditional ingredients to enhance modern therapeutic practices.
61) Arti:
'Arti' refers to pain, a common symptom in various health conditions. In the context of Vicharchika, understanding Arti is critical for developing effective management strategies that alleviate discomfort, underscoring Ayurveda’s holistic approach to addressing both symptomatic relief and emotional well-being.
62) Food:
'Food' in this context relates to dietary habits impacting health as per Ayurvedic principles. Understanding the link between diet and skin diseases like Vicharchika helps practitioners make dietary recommendations that promote balance and wellness, addressing underlying causes of skin issues through nutritional guidance.
63) Hair:
'Hair' plays a role in identifying certain skin conditions and their treatments. In contexts like Vicharchika, recognizing the relationship between hair health and skin disorders may uncover systemic issues that guide more comprehensive treatment approaches, underscoring interconnected health dynamics within Ayurveda.
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Ruja, Kandu, Kshudraroga, Shotha, Gomutra, Rukshata, Pidaka, Vicharchika, Bahusrava, Signs and symptoms, Topical application, Pruritus, Ayurvedic formulation, Clinical trial, Assessment criteria, Clinical assessment, Dermatitis, Efficacy, Statistical significant.