Exploring Dhupana: An Innovative Drug Delivery Method in Ayurveda
a drug delivery method
Journal name: World Journal of Pharmaceutical Research
Original article title: Dhupana karma
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Subtitle: a drug delivery method
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Dr. Manita Ahlawat, Dr. Reetu Sharma and Dr. S. K. Mandal
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Dhupana karma
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr201817-13451
Copyright (license): WJPR: All rights reserved
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Summary of article contents:
Introduction
The study presented by Ahlawat et al. explores the drug delivery method known as Dhupana, a traditional Ayurvedic therapy involving the administration of herbal drugs in the form of fumigation. This method represents an additional avenue for drug delivery within Ayurvedic practices, showcasing how traditional therapies can integrate with modern pharmaceutical approaches. The authors underscore the significance of this method, considering various aspects, including the scientific basis behind its effectiveness, the types of drug forms utilized, and the instrumentation involved in its application.
The Principle of Dhupana
Principles of Dhupana Karma indicates that this method is a modified version of Havana karma. The process involves igniting various medicinal herbs in a specific apparatus known as Agnikunda. The burning of these herbs releases active phytochemicals in a vapor phase, enabling the therapeutic properties of the drugs to be absorbed. Factors such as the nature of the drugs, the temperature controlled during the process, and the configuration of the Agnikunda play crucial roles in the efficiency of this drug delivery technique. The chanting of mantras during this process is believed to enhance its medicinal benefits, adding a spiritual dimension to the therapy.
Drug Forms Utilized in Dhupana
The effectiveness of the Dhupana method is closely tied to the form of the drugs used for fumigation. This technique primarily employs drugs in their coarse powdered form or as pastes (Kalka). The powdered drugs are ignited after being mixed with goat's urine, thereby producing therapeutic fumes. Interestingly, though historical references to Dhupavarti (a type of herbal preparation) in the therapeutic context are limited, its relevance is acknowledged as of significant interest. Various forms and preparations contribute to the overall efficiency of drug delivery, drawing from Ayurveda's long-established pharmacological practices.
The Mechanism and Efficacy of Fumigation
The physiological impact of medicinal fumes is a noteworthy concept as well. The research suggests that the smoke derived from burning herbal preparations contains nanosized active molecules, enhancing its therapeutic effects. The fumes allow for deep diffusion of active constituents into body tissues, targeting specific systems such as respiratory pathways and skin pores. This delivery method is posited to be less invasive compared to traditional routes, thereby offering a promising alternative for holistic treatment. The presence of volatile oils in the formulations is responsible for their easy diffusion and absorption at targeted sites within the body.
Conclusion
In conclusion, the Dhupana Karma offers a promising approach for drug delivery, fusing classical Ayurvedic methods with modern scientific understanding. The authors highlight the need for further research to standardize and refine this method, including the development of improved instrumentation for its application. By exploring the various facets of Dashupana, including its principles, drug forms, and physiological mechanisms, there is a call to recognize and leverage such traditional systems of medicine in contemporary healthcare. This study emphasizes the potential benefits of this ancient practice while advocating for deeper exploration and integration in modern pharmacology.
FAQ section (important questions/answers):
What is Dhupana in Ayurvedic drug delivery methods?
Dhupana is a traditional Ayurvedic fumigation therapy where herbal drugs are burned to release medicinal fumes. This method aims to enhance drug delivery for therapeutic purposes, utilizing the properties of volatile compounds in the herbs.
How does Dhupana compare to other drug delivery methods?
Unlike conventional methods like oral or topical administration, Dhupana employs fumes from burnt herbs, which can penetrate deeper into the body. This allows for systemic and localized therapeutic effects, potentially offering enhanced efficacy.
What types of drug forms can be used in Dhupana?
Drugs used in Dhupana can be in coarse powder form, paste (Kalka), or other derived preparations. The fumes produced during combustion are utilized for the therapeutic effects of the constituents.
What equipment is needed for Dhupana therapy?
Dhupana therapy traditionally uses an Agnikunda, an inverted pyramid-shaped container for burning herbs, and a specially designed Dhupana yantra for directing the emitted fumes towards the patient.
Why is Ghrita included in Dhupana formulations?
Ghrita, or clarified butter, is included in Dhupana formulations to optimize the production of fumes. It enhances the combustion process, improving the release of beneficial volatile compounds for better drug delivery.
What research supports the effectiveness of Dhupana Karma?
Studies indicate that the active constituents in medicinal smoke may be more effective than other extracts. Research suggests improved antimicrobial properties and better absorption of the volatile compounds through inhalation.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Exploring Dhupana: An Innovative Drug Delivery Method in Ayurveda”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Drug:
The keyword 'Drug' refers to any substance used for medical purposes, especially in the context of treatment or prevention of diseases. In the Ayurvedic system, understanding the properties, efficacy, and appropriate delivery methods of drugs is crucial for maximizing therapeutic outcomes. The study highlights various drug forms and innovative delivery techniques.
2) Dhupana:
'Dhupana' is a traditional Ayurvedic therapy involving the burning of herbal drugs to generate medicinal fumes. This method serves as a new approach to drug delivery and is believed to enhance the efficacy of therapeutic agents through inhalation, targeting localized or systemic effects on the body.
3) Karma (Karman):
'Karma' translates to 'action' or 'procedure' in the Ayurvedic context. It often refers to therapeutic methods or rituals designed to promote healing. Understanding 'karma' is essential in differentiating various treatment modalities, including 'Dhupana', which exemplifies how actions influence health outcomes.
4) Ayurveda (Ayus-veda):
'Ayurveda' is an ancient Indian system of medicine that emphasizes balance in bodily systems and uses natural remedies. It encompasses a holistic approach to health through diet, herbal treatments, yoga, and more. Its principles guide practical applications like the 'Dhupana' method discussed in the study.
5) Study (Studying):
'Study' denotes an academic investigation or review conducted to explore a specific subject. In this context, the study investigates 'Dhupana' as a drug delivery method in Ayurveda, analyzing traditional texts, modern literature, and experimental data to present a comprehensive overview of its therapeutic applications.
6) Vijnana:
'Vijnana' signifies knowledge or science, particularly in the context of Ayurveda. It emphasizes a deep understanding of principles and practices that govern health and healing. This keyword underscores the importance of integrating scientific insights into traditional healing methods like 'Dhupana' for improved efficacy.
7) Vikriti (Vikrti):
'Vikriti' refers to the concept of bodily imbalances or disorders in Ayurveda that manifest as diseases. Recognizing 'vikriti' is essential for personalized treatments. Understanding the utility of methods such as 'Dhupana' helps practitioners address specific imbalances through suitable therapeutic applications.
8) Havana:
'Havana' is a ritual burning of medicinal herbs, foundational to practices like 'Dhupana'. It symbolizes the transformation of substances into vapors, liberating therapeutic phytochemicals that can be utilized for healing, thereby bridging traditional practices with scientific inquiry into effective drug delivery.
9) Jaipur:
'Jaipur' is a city in India where the study authors are affiliated. Its inclusion emphasizes the geographical and institutional context of the research. Jain practices and educational institutes in Jaipur contribute to the preservation and advancement of Ayurveda, including methodologies like 'Dhupana'.
10) Roga:
'Roga' stands for diseases or ailments in the Ayurvedic context. It represents the need for appropriate treatment modalities to restore health. Understanding 'rogas' allows practitioners to select suitable therapies like 'Dhupana', which may offer alternative pathways for addressing specific health conditions.
11) Fire:
'Fire' is integral to the 'Dhupana' method, enabling the combustion of herbal materials to produce therapeutic fumes. It serves as a catalyst for transforming raw plant ingredients into bioactive compounds that the body can absorb, showcasing the practical application of elemental forces in healing.
12) Phytochemical:
'Phytochemical' refers to biologically active compounds derived from plants. These chemicals are central to Ayurvedic efficacy, including those released during 'Dhupana' therapy. Understanding their roles helps identify how specific plant constituents contribute to medicinal properties, guiding therapeutic applications and enhancing treatment outcomes.
13) Agnikunda (Agnikumda):
'Agnikunda' is an inverted pyramid container used in Ayurvedic rituals for burning herbs. It is significant in methods like 'Dhupana', facilitating the transformation of solid herbal substances into therapeutic volatilized compounds. Its design plays a critical role in controlling the combustion process.
14) Turmeric:
'Turmeric' is a widely studied spice known for its anti-inflammatory and antimicrobial properties. Its relevance in medicinal practices underscores its incorporation into 'Dhupana' therapies. Studies highlighting its phytochemical properties extend the narrative of traditional wisdom into modern scientific validation within herbal medicine.
15) Activity:
'Activity' refers to the biological effect or action of a substance in treating ailments. In the context of medicinal herbs used in 'Dhupana', understanding their activities informs practitioners about the potential therapeutic benefits and limitations, guiding more effective treatment strategies in Ayurveda.
16) Burning (Burn, Burned, Burnt):
'Burnt' signifies the process of combustion that transforms raw herbal substances into medicinal fumes in 'Dhupana'. This action is vital for the therapeutic efficacy of the method, highlighting combustion's role in facilitating the release of active ingredients for healing purposes.
17) Ghrita (Ghrta):
'Ghrita' or ghee is a significant ingredient in 'Dhupana' formulations, enhancing the quality and efficacy of the fumes produced. Its unique properties contribute to better combustion and absorption of phytochemicals, underscoring the synergy between traditional herbal practices and beneficial delivery methods.
18) Manita:
'Manita' refers to Dr. Manita Ahlawat, the lead author of the study. Her contributions highlight the roles of researchers in promoting traditional medicine by integrating ancient practices with contemporary scientific methods. Ahlawat's insights on 'Dhupana' reflect an initiative to validate and explore Ayurvedic methods further.
19) Powder:
'Powder' denotes the physical state of herbal medicines before combustion in 'Dhupana'. The degree of fineness can influence the release of active ingredients during burning, impacting efficacy in drug delivery. Understanding the preparation of powders is essential for optimizing therapeutic practices.
20) Kalka:
'Kalka' refers to a paste form of herbal medicines used in 'Dhupana'. This method allows for the effective release of active compounds when heated, enhancing therapeutic potency. Its incorporation demonstrates the versatility of dosage forms in Ayurveda, contributing to diverse treatment applications.
21) Ghi (Ghee):
'Ghee' is clarified butter used in Ayurvedic formulations, particularly in 'Dhupana'. It plays a crucial role in producing medicated fumes, aiding in the combustion of herbal materials, and ensuring effective delivery of phytochemicals. Its unique properties bolster the efficacy of traditional treatments.
22) Sharavasamputa (Sharava-samputa, Saravasamputa):
'Sarava-samputa' is a container used in 'Dhupana' procedures for holding the herbal paste over a heat source. Understanding this traditional instrument is vital for implementing effective fumigation therapies, showcasing the integration of craftsmanship and medicinal principles in Ayurvedic practice.
23) Indriyasthana (Indriya-sthana):
'Indriya-sthana' refers to an Ayurvedic text that discusses senses and perception, providing insights into how treatments like 'Dhupana' affect bodily systems. This connection emphasizes the holistic view of health in Ayurveda, where sensory experiences and therapeutic actions are interlinked.
24) Transformation (Transform, Transforming):
'Transformation' relates to the processes by which herbs change state during 'Dhupana', converting to vapors for delivery. This concept is important in Ayurveda, as it illustrates the dynamic nature of medicinal preparations, highlighting the significance of methods that optimize the bioavailability of therapeutic agents.
25) Discussion:
'Discussion' pertains to the analytical section of the study that synthesizes findings, exploring implications for Ayurvedic practices like 'Dhupana'. This part of the research engages with prior studies, debating potential benefits and areas for further investigation, thereby fostering a scientific dialogue on traditional therapies.
26) Science (Scientific):
'Science' represents the systematic and evidence-based approach to understanding health and disease. In exploring 'Dhupana', this study bridges ancient practices with scientific validation, advocating for the integration of traditional knowledge with contemporary scientific methodologies in the quest for effective healthcare solutions.
27) Container:
'Container' refers to any vessel used to hold materials during 'Dhupana', essential for managing the burning process. The design and material of the container directly influence the efficiency and effectiveness of the therapeutic fumes produced, underscoring the importance of correct equipment in Ayurvedic therapies.
28) Medicine:
'Medicine' signifies the science and practice of diagnosing, treating, and preventing illness. In the context of Ayurveda, it encompasses a wide range of practices, including 'Dhupana', which reflect a holistic approach to health, integrating physical, spiritual, and environmental aspects in treatment paradigms.
29) Indriya (Imdriya):
'Indriya' translates to 'senses' in Sanskrit. In Ayurvedic medicine, it emphasizes the role of sensory perception in the healing process and patient experience. Treatments like 'Dhupana' engage the senses, highlighting the sensory components of Ayurveda, and enriching patient-centered care.
30) Pradeha:
'Pradeha' is another traditional topical application method in Ayurveda. The mention of 'Pradeha' alongside 'Dhupana' indicates the spectrum of treatment modalities available, allowing practitioners to tailor their approaches based on patient needs and specific health conditions, showcasing the versatility of Ayurvedic medicine.
31) Kalpana:
'Kalpana' refers to the formulation or preparation of medicinal substances in Ayurveda. In the context of 'Dhupana', it encompasses the creative and traditional aspects of designing effective treatments, illustrating the intricate understanding required to deliver herbal medicines through various modalities successfully.
32) Kashaya (Kasaya):
'Kashaya' denotes a specific type of decocted herbal formulation in Ayurveda. Its mention emphasizes the diverse forms of drug application and delivery beyond 'Dhupana', reinforcing the holistic pharmacological approach of Ayurveda that includes multiple methods to cater to different health needs.
33) Mantra (Mamtra):
'Mantra' refers to sacred sounds or chants often used in Ayurvedic rituals. Its significance in therapies like 'Dhupana' indicates the holistic nature of Ayurvedic practices where verbal expressions are believed to enhance therapeutic outcomes, connecting the spiritual dimensions of health with practical interventions.
34) Yantra (Yamtra):
'Yantra' symbolizes tools or instruments utilized in Ayurvedic practices. In the context of 'Dhupana', understanding the 'yantra' is crucial for effective fumigation therapy, as proper instruments enhance the precision and effectiveness of herbal treatments, illustrating the interface of technology and tradition in medicine.
35) Caraka:
'Caraka' refers to the ancient Ayurvedic text that forms a cornerstone of classical medical knowledge. References to 'Caraka' in the study support the credibility of 'Dhupana', linking traditional practices to historic medical philosophies that underscore holistic health principles and comprehensive treatment methods.
36) Sharava (Sarava):
'Sarava' indicates the collection of herbs or components used in Ayurvedic formulations. Its meaning highlights the importance of custom blends of treatments like 'Dhupana', which relies on the synergistic effects of various ingredients, emphasizing the personalized nature of Ayurvedic therapy.
37) Sthana:
'Sthana' translates to 'place' or 'location' in Ayurveda, often referring to physiological spaces in the body. Understanding 'Sthana' is essential for developing targeted treatments like 'Dhupana', where the effectiveness of the therapy may greatly depend on its anatomical application and placement within bodily systems.
38) Kalaya:
'Kalaya' refers to a measurement unit related to the thickness of a pipe used in the 'Dhupana' apparatus. It emphasizes the importance of precision in devising tools for therapeutic applications, highlighting that even the smallest aspects of design can significantly impact treatment effectiveness.
39) Mandal:
'Mandal' refers to Dr. S. K. Mandal, one of the authors. His contributions are vital for collaborative research, refining the understanding of 'Dhupana' and other Ayurvedic methodologies, thereby enhancing the discourse around the relevance of traditional practices in modern healthcare.
40) Sharman (Sarma, Sarman, Sharma):
'Sharma' signifies Dr. Reetu Sharma, another contributing author. Her role underlines the necessity of diverse perspectives in research. Collaborative efforts contribute to comprehensive investigations into 'Dhupana', aiming to elucidate the significance of traditional therapies in enhancing modern medicinal frameworks.
41) Nature:
'Nature' reflects the innate characteristics and properties of herbal substances in 'Dhupana'. Recognizing the essence of each plant and its therapeutic potential is central to Ayurvedic practice, advocating for respect and understanding of nature within medicinal treatment and emphasizing sustainable practices.
42) Varti (Vartin):
'Varti' denotes unique formulations used in Ayurvedic therapies, specifically in certain contexts like 'Dhupana'. Its inclusion signifies the spectrum of drug delivery options available in Ayurvedic medicine, providing practitioners with a variety of tools and methods to cater to diverse health requirements.
43) Curna:
'Curna' refers to powdered herbal formulations commonly utilized in Ayurveda. In the context of 'Dhupana', the state of being in powdered form is critical for producing effective fumes, illustrating the importance of specific physical preparations in optimizing herbal efficacy.
44) Dhupa:
'Dhupa' is a term often associated with the fumes produced during therapeutic burning of herbs. It is a key concept for understanding 'Dhupana', emphasizing the significance of smoke as a medium for delivery of medicinal properties in traditional practices.
45) Basti:
'Basti' refers to a therapeutic enema in Ayurveda, illustrating the breadth of treatment methods available. Mentioning 'Basti' alongside 'Dhupana' reflects Ayurvedic medicine's diverse application approaches, reinforcing the idea that various methodologies can effectively address multiple health issues.
46) Lepa:
'Lepa' is a topical application used in Ayurveda, showcasing another route of drug delivery. Citing 'Lepa' indicates the diversity of therapeutic methods alongside 'Dhupana', emphasizing the comprehensive nature of Ayurvedic treatment strategies that cater to multiple patient needs.
47) Vati:
'Vati' refers to tablets or pill forms of Ayurvedic medicines. Including 'Vati' in the discussion of treatment options highlights the various forms drug delivery can take in Ayurveda, enhancing the understanding of how different formats can influence medicine's effectiveness and patient compliance.
48) Chun:
'Chun' represents a form of carbon material involved in therapeutic practices. Its association with the study emphasizes the incorporation of innovative materials into traditional healing methodologies, showcasing the potential of combining modern scientific discoveries with ancient medicinal practices.
49) Rich (Rch):
'Rich' suggests abundance or a high concentration of beneficial compounds. In the context of 'Dhupana', a rich concentration of phytochemicals in the generated smoke denotes enhanced therapeutic efficacy, underpinning the importance of the quality and preparation of herbal materials in achieving treatment goals.
50) Pur:
'Poor' describes suboptimal conditions or factors leading to unfavorable outcomes. Understanding 'poor' health conditions enables practitioners to tailor therapies such as 'Dhupana' to address specific needs, ensuring that the treatment strategies employed are effective in improving patients' health status.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Exploring Dhupana: An Innovative Drug Delivery Method in Ayurveda’. Further sources in the context of Science might help you critically compare this page with similair documents:
Drug delivery system, Traditional System of Medicine, Panchvidha Kashaya Kalpana, Dhupana Karma, Medicinal Smoke, Fumigation therapy, Effective administration, Volatile compound.
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