Study of pippali as a broad-spectrum antibiotic for chest infections.

| Posted in: Science

Journal name: World Journal of Pharmaceutical Research
Original article title: Conceptual study of judicious use of pippali as a broadspectrum antibiotic in various chest infections
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
This page presents a generated summary with additional references; See source (below) for actual content.

Original source:

This page is merely a summary which is automatically generated hence you should visit the source to read the original article which includes the author, publication date, notes and references.

Author:

Neha Kothari, Rupali Bedre, Kshama Dorle, Shital Kolpakwar and Snehal Deshmukh


World Journal of Pharmaceutical Research:

(An ISO 9001:2015 Certified International Journal)

Full text available for: Conceptual study of judicious use of pippali as a broadspectrum antibiotic in various chest infections

Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research

Doi: 10.20959/wjpr201817-13442

Copyright (license): WJPR: All rights reserved


Download the PDF file of the original publication


Summary of article contents:

Introduction

The recurring problem of chest infections and antibiotic resistance has prompted a re-evaluation of treatment methods, particularly the potential role of herbal medicines in combating these infections. Among various Ayurvedic herbs, Pippali (Piper longum) emerges as a promising candidate due to its demonstrated antimicrobial properties. This study highlights its efficacy against multiple pathogens, suggesting Pippali as a broadly applicable solution against resistant infections affecting the respiratory system.

Antimicrobial Properties of Pippali

Pippali is celebrated for its antimicrobial properties, exhibiting effectiveness against both gram-positive and gram-negative bacteria. It has been traditionally utilized in Ayurvedic medicine for treating conditions such as chronic cough and other respiratory ailments. The herb contains vital phytochemicals, including piperine, which contribute to its ability to combat bacterial growth. Various studies have indicated that the isolated proteins from Pippali can inhibit bacterial proliferation, making it a formidable option in the realm of alternative medicine aimed at treating resistant bacterial strains.

Bioavailability Enhancement

An important feature of Pippali is its capability to enhance the bioavailability of other therapeutic agents. This is particularly relevant in combination therapies, where Pippali acts as a yogvahi — or a carrier — that improves the effectiveness of other medicines. Research suggests that when Pippali is used alongside other herbs or drugs, it can facilitate improved absorption and reduce the first-pass metabolism effect, thereby amplifying the overall therapeutic impact. This bioavailability-enhancing property positions Pippali as a valuable ingredient in various formulations targeting chronic respiratory conditions.

Judicious Use of Pippali

While Pippali holds significant therapeutic potential, its application must be judiciously managed to prevent any adverse effects. Ayurvedic practitioners emphasize the importance of dosage tailored to the individual's condition, as inappropriate usage, particularly in excessive quantities, could lead to the aggravation of doshas (body energies). Understanding the specific health context, environment, and personal constitution is vital for maximizing the benefits of Pippali while minimizing risks. Methods such as Vardhman Pippali Rasayan (a protocol of gradual dosage increase and decrease) can optimize its therapeutic attributes while preventing the undesirable accumulation of doshas.

Conclusion

As antibiotic resistance becomes an increasingly pressing concern in modern medicine, exploring alternative remedies such as Pippali from Ayurvedic pharmacopoeia offers a new dimension to respiratory health management. The herb's antimicrobial qualities, coupled with its ability to enhance the effectiveness of other treatments, make it an encouraging candidate for further research. Future studies should focus on rigorous clinical trials to assess the efficacy, optimal dosing, and applications of Pippali in various respiratory conditions, which may lead to innovative strategies within integrative medicine practices.

FAQ section (important questions/answers):

What is the focus of the study on Pippali?

The study focuses on the judicious use of Pippali as a broad-spectrum antibiotic for treating various chest infections, particularly due to antibiotic resistance.

What are the key properties of Pippali mentioned?

Pippali is known for its antimicrobial, bioavailability enhancing capabilities, and potential to treat chronic cough and respiratory issues while maintaining a high safety profile.

How does Pippali compare to traditional antibiotics?

Pippali offers a safer alternative with a natural origin, effective against resistant bacteria, making it a valuable option in combating recurrent chest infections.

What are the recommended uses of Pippali in Ayurveda?

In Ayurveda, Pippali is used for treating cough, respiratory diseases, dyspepsia, fever, and as a bioavailability enhancer in various herbal formulations.

What is the significance of judicious use of Pippali?

Judicious use of Pippali ensures it provides therapeutic benefits while preventing adverse effects or aggravation of doshas when consumed in proper quantities.

What future studies are suggested regarding Pippali?

Future studies should explore Pippali’s dosage, duration of use, and its immunomodulatory effects in lung diseases, enhancing the evidence base for Ayurvedic treatments.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Study of pippali as a broad-spectrum antibiotic for chest infections.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Pippali (Pippalin):
Pippali, also known as Piper longum, is an important herb in Ayurveda renowned for its antimicrobial and bioavailability-enhancing properties. It plays a significant role in treating various respiratory conditions, including chronic cough, while exhibiting potential against pathogenic bacteria, making it relevant in developing alternative treatments for antibiotic-resistant infections.

2) Drug:
In the context of the study, a drug refers to any medicinal substance used to treat or prevent disease. Pippali is considered a herbal drug with multiple pharmacological effects, including enhancing the efficacy of traditional drugs and potentially serving as a broad-spectrum antibiotic against resistant bacteria.

3) Antibiotic (Antibacterial):
Antibacterial agents combat bacterial infections. Pippali is highlighted for its antibacterial properties, showcasing its effectiveness against common respiratory pathogens. This underscores the importance of exploring herbal alternatives in light of rising antibiotic resistance, promoting a shift towards natural healing methodologies.

4) Disease:
A disease refers to a pathological condition affecting the body. In this study, chest infections like pneumonia and bronchitis represent significant health challenges amplified by antibiotic resistance. The research underscores the need for effective treatments, particularly herbal medicines like Pippali, to manage these diseases safely and effectively.

5) India:
India, where the study is conducted, is a land rich in traditional medicine practices, particularly Ayurveda. The exploration of Pippali and other indigenous herbs reflects the cultural and historical significance of herbal medicine in India, aiming to integrate these practices into modern healthcare approaches to combat illnesses.

6) Study (Studying):
The study focuses on the usage of Pippali as an alternative therapeutic agent against chest infections. It reviews existing literature and the herb's antimicrobial properties, facilitating a deeper understanding of its potential roles in treating recurrent infections, thereby contributing to both scientific knowledge and practical applications.

7) Dosha (Dosa):
In Ayurveda, 'dosha' refers to the biological energies that govern physiological and psychological functions. It is critical in understanding individualized treatments. Pippali’s influence on doshas, particularly its ability to aggravate or alleviate them depending on preparation, underlines the need for judicious use in therapy.

8) Maharashtra (Maharastra, Maha-rashtra):
Maharashtra is a state in India where the research was conducted, highlighting its regional contribution to Ayurvedic education and practice. The study's authors are affiliated with medical institutions in Maharashtra, emphasizing the local significance of Ayurvedic research and its applications in public health.

9) Ayurveda (Ayus-veda):
Ayurveda is an ancient Indian system of medicine that emphasizes balance in bodily systems using herbal remedies and lifestyle adjustments. The study acknowledges Ayurveda’s holistic approach, particularly in exploring Pippali as a potential treatment for infections, underscoring its relevance in contemporary healthcare.

10) Species:
Species refers to different types of bacteria, particularly those causing chest infections. The study explores Pippali’s effects on various bacterial species, including both gram-positive and gram-negative types. Understanding interactions with specific pathogens is essential for developing effective herbal remedies against infections.

11) Medicine:
Medicine encompasses practices aimed at preventing and treating illness. In this context, the research investigates how Pippali fits into the broader category of medicinal treatments as a potential herbal alternative to conventional drugs, particularly in fighting bacterial infections.

12) Nagapura (Naga-pura):
Nagpur is a city in Maharashtra where some study authors are affiliated with local Ayurvedic institutions. The city's involvement in Ayurvedic education enriches the research landscape by contributing local knowledge and practices to the exploration of Pippali in modern medicine.

13) Fever:
Fever is a common symptom of many infections, including those of the respiratory system. The study examines Pippali's potential efficacy in treating fevers associated with chronic infections, suggesting its traditional use in managing febrile conditions amidst rising antibiotic resistance.

14) Fight:
To fight refers to efforts in combating infections, particularly bacterial diseases. This research emphasizes the need for alternative strategies, such as using Pippali, to fight against recurrent and antibiotic-resistant chest infections, advocating for the integration of herbal solutions into treatment plans.

15) Accumulation (Accumulating, Accumulate):
Accumulation refers to the buildup of doshas or imbalances in the body when substances like Pippali are used improperly. Understanding this concept is essential for ensuring its effective application in treatment while avoiding adverse effects, aligning with Ayurvedic principles of balance.

16) Aureus:
Aureus typically refers to Staphylococcus aureus, a common and often resistant pathogenic bacterium. The study explores Pippali's efficacy against this specific pathogen, highlighting the herb’s potential role in addressing important public health challenges related to antibiotic resistance.

17) Guna:
Guna in Ayurveda refers to the qualities or properties of substances that affect their therapeutic effectiveness. This study relates Pippali’s various gunas, which influence its medicinal applications, particularly in exacerbating or alleviating doshas, thereby guiding its use in treatment strategies.

18) Pharmacological:
Pharmacological studies investigate the effects of drugs, including herbs like Pippali. The research highlights Pippali's pharmacological properties, emphasizing its antimicrobial capabilities and potential as a natural antibiotic, thus linking traditional practices with contemporary scientific understanding.

19) Inflammation:
Inflammation is a pivotal process in many diseases, including those of the respiratory system. The study discusses how Pippali may address inflammation caused by bacterial infections, emphasizing its multifaceted role in treatment and the importance of resolving pathogenic conditions.

20) Samhita:
Samhita refers to classical Ayurvedic texts that serve as foundational literature for Ayurvedic knowledge. The study relies on various Samhitas to validate the traditional uses of Pippali, linking historical practices with modern scientific research and applications.

21) Trikatu (Tri-katu):
Trikatu is an Ayurvedic formulation containing Pippali, black pepper, and ginger, known for enhancing bioavailability of drugs. The study refers to Trikatu in discussing Pippali's synergistic properties, highlighting its significance in increasing the effectiveness of other herbal medicines and treatments.

22) Powder:
Powder is a common form in which Pippali and other herbs are administered in Ayurveda. The study suggests that using Pippali in powdered form can optimize its therapeutic effects, particularly its antimicrobial properties in treating chest infections safely.

23) Piper longum:
Piper longum is the scientific name for Pippali, a key herb examined in the study. Understanding its biological and therapeutic properties is fundamental in exploring its role as an alternative treatment for respiratory infections amid rising antibiotic resistance.

24) Tuberculosis:
Tuberculosis (TB) is a serious bacterial infection affecting the lungs. The study highlights the relationship between Pippali and respiratory conditions, considering its potential application in managing infections like TB, thus drawing attention to the herb's importance in contemporary public health concerns.

25) Pittadosha (Pittadosa, Pitta-dosha):
Pitta-dosha represents one of the three fundamental energies in Ayurveda associated with heat and metabolism. The study notes Pippali's influence on Pitta, elaborating on the need for careful dosage to avoid aggravating this dosha, critical for individual treatment strategies.

26) Chandrapur:
Chandrapur is another city in Maharashtra related to the authors’ affiliations, showcasing the geographical context of the research. This local aspect emphasizes the rich Ayurvedic heritage of the region and its influence on studying herbs like Pippali.

27) Discussion:
Discussion refers to the analytical interpretation of findings and implications related to Pippali's use in treating infections. This section provides insights into the herb's potential roles, summarizing evidence and reinforcing the need for further research into its applications in healthcare.

28) Science (Scientific):
The term scientific relates to the systematic study of phenomena through observation and experimentation. The research aims to provide scientific validation for Pippali's antimicrobial properties, bridging traditional Ayurvedic practices with contemporary scientific methodologies and inquiries.

29) Substance:
A substance refers to any material with distinct properties and effects. In the context of this study, Pippali as a substance is evaluated for its medicinal qualities, particularly as a potential alternative to traditional antibiotics in treating infections.

30) Rasayani:
Rasayani refers to rejuvenating or immune-boosting remedies in Ayurveda. The study emphasizes Pippali's role in fostering resilience against diseases, highlighting its application as a Rasayani, which underlines the holistic aspect of treatment in Ayurvedic practices.

31) Himalaya (Hima-alaya):
Himalaya, the mountain range in Asia, is often associated with the origin of many medicinal herbs, including Pippali. This geographical significance indicates the natural habitat of the plant, reinforcing the importance of traditional knowledge and natural resources in Ayurvedic medicine.

32) Vrishya (Vrsya):
Vrishya means an aphrodisiac in Ayurveda, indicating Pippali's diverse properties. The study mentions this aspect to illustrate the wide-ranging benefits of Pippali, demonstrating its multifaceted role in traditional practices beyond mere treatment of infections.

33) Amavata (Ama-vata):
Amavata refers to a condition resembling rheumatism in Ayurveda. The study connects Pippali’s properties to conditions like Amavata, reinforcing its anti-inflammatory and restorative qualities, which may provide a broader scope for its therapeutic application.

34) Kashaya (Kasaya):
Kashaya denotes an Ayurvedic preparation that can aid in treatment. The study highlights formulations like Kashaya incorporating Pippali, illustrating its application in broader Ayurvedic remedies for enhancing its therapeutic effectiveness in infections and respiratory issues.

35) Quality:
Quality pertains to the effectiveness and safety of herbal medications. The study emphasizes that understanding the quality of Pippali and proper preparation methods is crucial in ensuring its therapeutic success in treating infections and promoting overall health.

36) Overuse:
Overuse refers to an excessive application of antibiotics leading to resistance. In the study, the repercussions of antibiotic overuse stress the need for herbal alternatives like Pippali, aimed at mitigating the public health crisis posed by resistant infections.

37) Leprosy:
Leprosy is a chronic infectious disease referenced in the context of Pippali’s historical usage in Ayurvedic practices. The study highlights the herb's comprehensive therapeutic applications, linking past medicinal knowledge to contemporary issues in managing a wide range of diseases.

38) Dealing:
Dealing with resistance to antibiotics is highlighted as a significant concern in modern medicine. The study emphasizes Pippali's potential to tackle this challenge, citing its historical effectiveness in treating infections, thus advocating for its renewed relevance in contemporary healthcare.

39) Filling (Filled):
Filling refers to addressing gaps in current research. This study aims to fill the void in understanding how Pippali can function as an effective antibiotic alternative, while promoting its integration into modern medical practices as a viable treatment option for infections.

40) Vimala:
Vimala refers to one of the Ayurvedic institutions associated with the authors. This affiliation showcases the educational and research culture in Maharashtra focused on exploring traditional medicines like Pippali for modern health challenges.

41) Kshama (Ksama):
Kshama is the name of one of the authors, contributing to the research. Individual contributions symbolize the collaborative approach towards understanding and advancing Ayurvedic practices, ultimately seeking to integrate these approaches into mainstream medicine for public health.

42) Family:
Family refers to the taxonomical classification category within which Pippali (Piper longum) is classified. Understanding its family contextualizes its biological characteristics and therapeutic properties, critical in validating its traditional uses and exploring new research avenues.

43) Nature:
Nature refers to the natural characteristics and environment in which Pippali thrives. This aspect reinforces the significance of sourcing high-quality herbal ingredients for traditional medicine, important in maximizing Pippali's efficacy in treatments.

44) Kriya:
Kriya in Ayurveda denotes therapeutic actions. The study explores how Pippali’s Kriya can be effectively harnessed to treat various conditions, emphasizing the importance of understanding its active role in enhancing health and well-being through Ayurvedic principles.

45) Pitta:
Pitta, one of the three doshas, governs metabolic processes. The study highlights Pippali’s role in balancing Pitta, emphasizing its conditional effects on health and disease, which is critical for personalized treatment in Ayurveda.

46) Ushna (Usna):
Ushna refers to the hot or heating qualities of Pippali. The study underlines the importance of considering Ushna when utilizing the herb, as it is essential for ensuring proper dosages to achieve therapeutic outcomes without causing adverse effects.

47) Dhatu:
Dhatu refers to the seven bodily tissues in Ayurveda pivotal for maintaining health. The study mentions Pippali’s Rasayani properties that enhance the quality of Dhatus, emphasizing the herb's supportive role in restoring balance and improving overall health.

48) Arshas (Arsa, Arsha, Arsas):
Arsha refers to piles or hemorrhoids in Ayurveda. The study highlights Pippali's historical applications in treating conditions like Arsha, showcasing its broader relevance within traditional medicinal practices beyond targeting just respiratory issues.

49) House:
House denotes the repository of traditional knowledge and practices in Ayurveda. The study emphasizes the role of Ayurvedic schools and institutions as houses of learning, underscoring their contribution to advancing herbal medicine, including studies on Pippali.

50) Salt (Salty):
Salty refers to the taste and properties influencing Ayurvedic treatments. The study links the salty aspect of Pippali with its therapeutic uses, emphasizing the need for understanding the holistic effects of taste in treatment plans.

51) Roga:
Roga denotes disease or disorder in Ayurveda. The study focuses on Pippali's role in treating various Rogas, positioning it as a crucial element in devising effective herbal interventions within traditional medicinal frameworks.

52) Medas (Meda, Medash):
Meda refers to body fat or lipid tissues in Ayurvedic context. Understanding Pippali's influence on Meda contributes to its application in holistic therapies, emphasizing its significance in managing conditions related to fat metabolism and overall health.

53) Devi:
Devi refers to Shrimati Vimala Devi Ayurvedic Medical College, one of the institutions associated with the authors. It represents the scholarly environment contributing to research and exploration of herbal treatments like Pippali in contemporary medical studies.

54) Vayu:
Vayu signifies air, one of the three doshas in Ayurveda responsible for movement and communication in the body. The study references Pippali’s action upon Vayu, illustrating its therapeutic versatility and significance in balancing physiological functions.

55) Pain:
Pain indicates a symptom often associated with various infections, including respiratory conditions. The study emphasizes how Pippali could be useful in mitigating pain related to such conditions, thereby showcasing its potential to enhance patient comfort and recovery.

56) Milk:
Milk signifies a vehicle in Ayurveda for administering herbs like Pippali. This study mentions the use of milk in preparing Pippali formulations, highlighting the importance of combining ingredients to enhance therapeutic effects and patient acceptability.

57) Post:
Post refers to the conclusion or follow-up actions relating to the study findings. The study advocates for further research and applications of Pippali in modern medicine, indicating the post-study implications for continuing the exploration of Ayurvedic solutions to health challenges.

Other Science Concepts:

[back to top]

Discover the significance of concepts within the article: ‘Study of pippali as a broad-spectrum antibiotic for chest infections.’. Further sources in the context of Science might help you critically compare this page with similair documents:

Trikatu, Long pepper, Herbal medicine, Chronic cough, Judicious use, Antimicrobial properties, Ayurvedic text, Gram-positive and Gram-negative bacteria, Bioavailability enhancer, Broad spectrum antibiotic, Resistant pathogens.

Let's grow together!

I humbly request your help to keep doing what I do best: provide the world with unbiased sources, definitions and images. Your donation direclty influences the quality and quantity of knowledge, wisdom and spiritual insight the world is exposed to.

Let's make the world a better place together!

Like what you read? Help to become even better: