Photochemical screening of plants mucana prurita, mesua ferrea, punica granatum

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Journal name: World Journal of Pharmaceutical Research
Original article title: Photochemical screening of plants mucana prurita, mesua ferrea, punica granatum
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Original source:

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Author:

Sonu Sharma and Dr. Ashish Kumar Sharma


World Journal of Pharmaceutical Research:

(An ISO 9001:2015 Certified International Journal)

Full text available for: Photochemical screening of plants mucana prurita, mesua ferrea, punica granatum

Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research

Doi: 10.20959/wjpr20172-7719


Download the PDF file of the original publication


Summary of article contents:

Introduction

The research article discusses the photochemical screening of three significant plants—Mucuna prurita, Mesua ferrea, and Punica granatum—known for their traditional use in herbal medicine in India. Given the reliance on traditional medicine among many populations and a growing demand for herbal remedies, this study aims to evaluate the medicinal properties of these plants, particularly in their roles as antifertility agents in women and aphrodisiacs. The increasing population growth and the need for safer, natural alternatives to synthetic contraceptives further emphasize the relevance of such research.

Importance of Phytochemical Studies

Phytochemical studies are essential for the extraction and isolation of beneficial compounds from plant materials. Different extraction methods such as infusion, decoction, and maceration are discussed, each suitable for particular types of plant constituents and their physical properties. The extraction process is influenced by factors such as the nature of the plant, the extraction time, and the choice of solvent. For instance, the use of solvents like ethanol and petroleum ether is crucial in isolating specific phytoconstituents that confer the medicinal properties of the plants. Properly executed phytochemical investigations can unveil the diversity of bioactive compounds, thereby supporting their pharmacological evaluations.

Chromatographic and Spectral Analysis

The application of chromatography and spectral analysis is pivotal for understanding and quantifying the components present in the plant extracts. Techniques such as Thin Layer Chromatography (TLC) and High-Performance Thin Layer Chromatography (HPTLC) are utilized to separate and identify specific phytochemicals. This study also highlights the importance of UV and FTIR spectroscopy in characterizing the chemical structure of isolated compounds, such as beta-sitosterol and eugenol, offering insights into their functional groups. These analytical methods allow researchers to establish the presence of bioactive compounds and their potential therapeutic effects, ultimately validating traditional uses.

Phytochemical Composition and Biological Activities

The quantitative yield of various extracts from the three plants reveals a rich profile of phytoconstituents, including alkaloids, flavonoids, tannins, and glycosides. The study indicates that the extracted compounds exhibit a range of biological activities such as aphrodisiac, anti-inflammatory, and antidiabetic properties. Specifically, the presence of certain secondary metabolites is linked to the pharmacological effects associated with the use of these plants in traditional medicine. Such findings support the notion that traditional herbal remedies may provide safe and effective therapeutic options.

Conclusion

In conclusion, the study underscores the significance of Mucuna prurita, Mesua ferrea, and Punica granatum in traditional medicine, while advancing the scientific understanding of their chemical composition and biological activities through thorough phytochemical analysis. The integration of modern analytical techniques enhances the credibility of traditional claims and paves the way for further research into natural medicinal products. As the demand for safer and more effective herbal alternatives grows, these plants may play a crucial role in developing innovative therapies and addressing public health needs.

FAQ section (important questions/answers):

What plants were studied for their medicinal properties?

The study investigated the medicinal properties of Mucuna prurita, Mesua ferrea, and Punica granatum, which have been traditionally used for antifertility and aphrodisiac purposes.

What extraction methods were used in this study?

Extraction methods included petroleum ether extraction, ethanol extraction, and aqueous extraction using Soxhlet apparatus, followed by filtration and solvent removal under reduced pressure.

What were the findings regarding phytoconstituents in extracts?

The extracts contained various phytoconstituents such as alkaloids, flavonoids, tannins, and more, with differences noted across petroleum ether, ethanol, and aqueous extracts.

How were the extracts analyzed for their composition?

The extracts were analyzed using techniques such as TLC, UV spectroscopy, and FTIR, which helped identify and quantify specific compounds present in the extracts.

What were the percentage yields for each type of extract?

The study found yields of 0.52% for petroleum ether extract, 3.43% for ethanol extract, and 8.1% for aqueous extract, indicating better extraction efficiency with water.

Why is there a growing need for herbal aphrodisiacs?

With rising population and synthetic contraceptives causing side effects, there is an increasing demand for natural aphrodisiacs derived from herbal sources that are safer and effective.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Photochemical screening of plants mucana prurita, mesua ferrea, punica granatum”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Sharman (Sarma, Sarman, Sharma):
Sharma refers to Sonu Sharma, a key researcher involved in the study. His contributions include the chemical and pharmacological evaluation of various medicinal plants. His work aims to uncover the therapeutic potentials of traditional herbs, providing a scientific basis for their use in contemporary healthcare.

2) Water:
Water is the universal solvent used in the extraction processes described in the study. It is crucial for preparing aqueous extracts from plant materials, allowing beneficial phytochemicals to dissolve. Its role emphasizes the importance of solvent choice in achieving effective extraction while maintaining the integrity of the compounds.

3) Powder:
Powder refers to the processed form of the plant materials that undergo extraction to obtain various phytochemical extracts. The powder's particle size affects extraction efficiency and solvent interaction, making it a critical factor in the preparation of herbal remedies and subsequent pharmacological studies.

4) Mesua ferrea:
Mesua ferrea is one of the three medicinal plants investigated in the study. Traditionally used for its medicinal properties, it is examined for its bioactive compounds that may support health, particularly in the treatment of various conditions like fever and skin ailments. Understanding its efficacy helps validate its traditional uses.

5) Table:
Table refers to the organized representation of data throughout the study, used for reporting percentage yields, fluorescence studies, and qualitative analyses of the extracts. Tables are essential in scientific literature as they facilitate clarity, making complex information more accessible for researchers and practitioners.

6) Punica granatum:
Punica granatum, or pomegranate, is another plant evaluated for its medicinal properties. It holds historical significance in traditional medicine for its various health benefits. The analysis of this plant contributes to the understanding of its active constituents that may provide therapeutic effects against multiple diseases.

7) Drug:
Drug denotes bioactive compounds obtained from the studied plants, which have potential therapeutic uses. The research aims to identify these compounds, exploring their pharmacological effects and validating their traditional medicinal claims, which is essential for drug development and improving health outcomes.

8) Performance:
Performance refers to the efficiency and effectiveness of various extraction and analysis methods used in the study. It assesses how well these techniques isolate bioactive compounds from the plant materials, contributing to the overall success of pharmacological evaluations and advancing herbal medicine research.

9) Phytochemical:
Phytochemical pertains to the chemical compounds found in plants that are studied for their potential health benefits. The research focuses on exploring the phytochemical profile of the evaluated plants, determining their biological activity, and validating their traditional uses in medicine, enhancing the understanding of herbal remedies.

10) Developing:
Developing refers to the process of enhancing analytical techniques, such as chromatography, for effectively isolating and identifying compounds within the plant extracts. This process is vital for achieving reliable results in studies that aim to characterize the therapeutic properties of medicinal plants.

11) Beta:
Beta often refers to beta-sitosterol, a common phytosterol isolated in the study. It is studied for its potential health benefits, including cholesterol-lowering effects and anti-inflammatory properties. Understanding its prevalence in the examined plants contributes to the evaluation of their therapeutic profiles.

12) Substance:
Substance refers to the specific chemical components obtained from plant extracts. Identifying and quantifying these substances is key to understanding their pharmacological activities, which underpins the medicinal value of the plants being studied and supports their integration into healthcare practices.

13) Medicine:
Medicine encompasses the branch of science that deals with the diagnosis, treatment, and prevention of disease. The study highlights traditional herbal medicine's relevance, seeking to scientifically validate its efficacy and safety, thus bridging the gap between traditional practices and modern pharmacology.

14) Nature:
Nature refers to the source of the medicinal plants studied, emphasizing the importance of natural herbs in providing safe and effective therapeutic options. The research advocates for the exploration of natural substances as a means to develop new medicines with fewer side effects compared to synthetic drugs.

15) Glass:
Glass is relevant in the study as it pertains to the laboratory equipment used for extracting and analyzing plant materials. Various glassware, like flasks and bottles, are essential for maintaining the integrity of samples during experimentation, influencing the accuracy of the results obtained.

16) Flavonoid:
Flavonoid refers to a class of plant secondary metabolites examined in the study for their potential health benefits, including antioxidant and anti-inflammatory effects. Their presence in the extracts contributes to understanding the therapeutic value of the plants and supports their traditional uses in medicine.

17) Quality:
Quality refers to the purity and efficacy of the herbal extracts produced from the studied plants. Ensuring high quality in extraction processes is essential for developing reliable medicinal products, emphasizing the importance of standardized methods in the pharmaceutical industry for effective treatments.

18) Heating:
Heating is part of the extraction process where plant materials are subjected to heat to facilitate the solubility of bioactive compounds in solvents. This step is crucial for ensuring efficient extraction and obtaining potent extracts with desired therapeutic properties from the plant material.

19) Surface:
Surface refers to the area of interaction between the solvent and plant material during extraction. The surface area affects the extraction efficiency, as a larger surface area can enhance solvent penetration, leading to a more effective isolation of phytochemicals from the plant matrix.

20) Jaipur:
Jaipur is the location of the Nims Institute of Pharmacy, where the research is conducted. Its relevance lies in representing the geographical context of the study, linking traditional medicinal knowledge with contemporary scientific approaches to health care prevalent in this region of India.

21) Medium:
Medium typically refers to the solvent or environment used in the extraction processes discussed in the study. Different mediums, such as aqueous or organic solvents, play a pivotal role in determining the yield and quality of the extracted phytochemicals, influencing the research findings.

22) Filling (Filled):
Filled pertains to the process of completing extraction equipment, like Soxhlet apparatus, with plant material and solvent. Properly filling the apparatus ensures efficient extraction and maximizes the yield of desired bioactive compounds, which is critical for the study's pharmacological evaluations.

23) India:
India is the country of focus for the study, known for its rich cultural heritage in traditional medicine. The research aims to explore indigenous medicinal plants, contributing to the global knowledge on herbal remedies, reinforcing India's role in the field of herbal pharmacotherapy.

24) Ulcer:
Ulcer refers to a medical condition often treated with the medicinal plants studied. Understanding the potential efficacy of these plants against ulcers supports the traditional medicinal claims, providing a scientific basis for their use in treating gastrointestinal disorders and enhancing patient health.

25) Pharmacological:
Pharmacological relates to the study of how drugs interact with biological systems. The research investigates the pharmacological activities of the extracted compounds, seeking to understand their mechanisms of action and therapeutic potential, which is fundamental for drug development and clinical application.

26) Purification:
Purification pertains to the processes used to isolate and remove impurities from the extracts obtained from the plants. Ensuring the purity of extracts is vital for obtaining reliable data regarding their bioactive components, which influences the quality and efficacy of herbal medicinal preparations.

27) Measurement:
Measurement refers to the quantitative assessment techniques employed throughout the study to determine the concentration and efficacy of the extracted compounds. Accurate measurement is essential for validating the therapeutic potential of the plants and supporting their use in traditional medicine.

28) Discussion:
Discussion is a section of the study where results are interpreted and contextualized within existing literature. It offers insights into the implications of the findings, addressing their relevance to traditional medicine and providing directions for future research in the field of herbal pharmacology.

29) Resolving:
Resolving refers to the separation of chemical compounds during chromatographic analysis. It is a critical step in identifying and quantifying the active constituents in the extracts, facilitating a better understanding of the therapeutic potential and supporting the efficacy of the studied plants.

30) Transformation (Transform, Transforming):
Transform refers to the process of converting raw plant materials into extracts through various methods. This transformation is essential in herbal medicine as it enhances the bioavailability of active ingredients, making them more effective for therapeutic applications in human health.

31) Activity:
Activity refers to the biological effects exhibited by the compounds extracted from the studied plants. The study examines the pharmacological activity of these compounds, contributing to the understanding of their potential use in treating various ailments and validating traditional medicinal practices.

32) Study (Studying):
Study pertains to the comprehensive investigation undertaken to explore the medicinal properties of the selected plants. It encompasses methodologies, analyses, and interpretations aimed at substantiating traditional uses and contributing to the field of herbal pharmacology and its applications.

33) Debility:
Debility refers to a condition of weakness or incapacity often addressed by traditional medicine. The research investigates the therapeutic potential of selected plants in alleviating symptoms related to debility, highlighting their relevance in enhancing overall health and quality of life.

34) Leprosy:
Leprosy is mentioned as one of the conditions that might be treated with the plant extracts. Investigating the effectiveness of the selected plants against leprosy emphasizes the need for traditional remedies in treating chronic conditions and supports the scientific validation of these practices.

35) Disease:
Disease pertains to the various health conditions that the studied plant extracts aim to treat. Understanding the impact of bioactive compounds on diseases reinforces the importance of research in traditional herbal medicine, supporting the integration of such remedies into modern healthcare systems.

36) Species:
Species refers to the specific plants being studied, including Mucuna prurita, Mesua ferrea, and Punica granatum. Identifying and understanding the properties of various species is essential for recognizing their unique benefits and roles in traditional medicine and pharmacotherapy.

37) Falling:
Falling may refer to the continuous decline in health or quality of life due to untreated diseases. The study addresses traditional medicinal plants that could potentially reverse this trend, promoting better health outcomes through the exploration of natural therapeutic agents.

38) Siddha:
Siddha is a traditional healing system in India that emphasizes herbal and natural remedies. The study values this heritage, aiming to bridge traditional knowledge with scientific inquiry, ultimately promoting the efficacy of Siddha practices and their relevance in modern healthcare.

39) Cotton:
Cotton refers to the materials used in laboratory settings, such as cotton plugs in chromatography, which are vital for separating substances during extraction processes. Its relevance underscores the importance of proper techniques and materials in achieving successful results in pharmacological studies.

40) Kumar:
Kumar refers to Dr. Ashish Kumar Sharma, a co-author in the study. His role, alongside Sonu Sharma, strengthens the research, adding to the credibility and depth of the findings regarding the potential benefits of the investigated medicinal plants.

41) Fever:
Fever is a common health issue often treated with traditional remedies. The study explores the potential of the selected plants to address fever symptoms, validating the traditional practices associated with these species and supporting their use in modern therapeutic applications.

42) House:
House refers to the environment where various experimental procedures are conducted, emphasizing the need for a controlled and systematic approach in the pursuit of high-quality research. The laboratory setting is crucial for achieving accurate and reproducible results in the study.

43) Tank:
Tank refers to the apparatus used during the extraction and development processes, such as chromatographic tanks that facilitate solvent movement. Proper tank design is critical for ensuring effective separation and measurement of the extracted compounds in a laboratory setting.

44) Rich (Rch):
Rich emphasizes India's extensive biodiversity and cultural heritage in the realm of herbal medicine. The study showcases the importance of preserving this biodiversity and harnessing traditional knowledge to discover new therapeutic agents from natural resources, thus influencing global health practices.

Other Science Concepts:

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Discover the significance of concepts within the article: ‘Photochemical screening of plants mucana prurita, mesua ferrea, punica granatum’. Further sources in the context of Science might help you critically compare this page with similair documents:

Punica granatum, Flavonoid, Traditional medicine, Herbal medicine, Phytochemical screening, Phytochemical analysis, Secondary metabolite, HPTLC analysis, Chromatographic analysis, Biological activities, Extraction method, Glycosides, Safety margin, Solvent extraction.

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