Efficacy of swarnamakshik bhasma in garavishjanit amlapitta.
Journal name: World Journal of Pharmaceutical Research
Original article title: Efficacy study of swarnamakshik bhasma with kshaudra and sharkar in garavishjanit amlapitta.
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Dr. Dipika
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Efficacy study of swarnamakshik bhasma with kshaudra and sharkar in garavishjanit amlapitta.
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr20173-7938
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Summary of article contents:
Introduction
The study presented in this article investigates the efficacy of a compound called Swarnamakshik Bhasma when used in conjunction with Kshaudra and Sharkara in treating Garavishajanit Amlapitta, a digestive disorder rooted in the concept of Viruddhahar or incompatible food combinations. A total of 40 patients diagnosed with this condition were split into two groups: one group received the trial drug while the other acted as a control group receiving contemporary symptomatic treatment as required. The trial ran for 30 days, and various subjective parameters were evaluated weekly to understand the effects of the treatment.
Significance of Viruddhahar
Viruddhahar, which can be translated as the concept of incompatible food combinations, is a critical factor in the development of Amlapitta. According to ancient Ayurvedic texts, the consumption of such food leads to a disturbance in the doshas (body energies)—specifically vitiating Agni (digestive fire)—and results in Agnimandya (digestive impairment). This dysregulation can cause the formation of shuktaahar rasa (improperly processed food), which in turn can lead to ailments like Amlapitta. The study underscores the importance of understanding dietary compatibility in managing digestive disorders and illustrates how certain Ayurvedic formulations can help mitigate the adverse effects of such habits.
Efficacy of Swarnamakshik Bhasma
The trial drug, Swarnamakshik Bhasma combined with Kshaudra and Sharkara, showed significant therapeutic effects on the symptoms of Garavishajanit Amlapitta. The formulation was based on detailed Ayurvedic principles, with each ingredient chosen for its specific beneficial properties—like Kshay, Madhura (sweet) taste, and Sheet virya (cool potency). Results indicated significant improvement in subjective parameters such as Hriddaha (heartburn), Kanthdaha (throat pain), and others among those treated with the trial drug, confirming the hypothesis that these Ayurvedic formulations can effectively counteract the vitiated Pitta dosha.
Impact of the Clinical Trial
The clinical trial was rigorously designed, involving an initial pilot study that established the prevalence of Viruddhahar and Amlapitta among patients. After receiving necessary medical clearance from an Institutional Ethics Committee, the patients were randomly divided into control and trial groups. Statistical analysis revealed that, of the eight subjective symptoms considered, seven demonstrated statistically significant improvement in the trial group compared to the control group. This reinforces the potential of Ayurvedic treatment in addressing not just symptoms but potentially the root causes of digestive disorders.
Conclusion
The efficacy study of Swarnamakshik Bhasma combined with Kshaudra and Sharkara has been demonstrated as clinically effective in treating Garavishajanit Amlapitta. The results highlight the importance of utilizing traditional Ayurvedic medicine in addressing modern health concerns, particularly in the context of dietary indiscretion and its implications on digestive health. Overall, the findings suggest that such formulations may offer a significant alternative treatment avenue that can lead to meaningful patient outcomes in the context of Ayurvedic therapies.
FAQ section (important questions/answers):
What is the purpose of the study on Swarnamakshik Bhasma?
The study aimed to evaluate the efficacy of Swarnamakshik Bhasma combined with Kshaudra and Sharkara in treating Garavishajanit Amlapitta, a condition caused by improper dietary habits.
What methodology was used in the clinical trial?
An open randomized clinical trial was conducted with 40 patients split into trial and control groups. The trial group received a combination of trial drugs, while the control group received symptomatic treatment as needed.
What were the main outcomes measured in the study?
The efficacy was assessed based on eight subjective parameters, including symptoms like Hriddaha, Kanthdaha, and Aruchi. Weekly follow-ups were conducted to monitor symptom reduction.
What were the significant findings of the trial?
The trial showed significant symptom reduction in seven of the eight parameters in the trial group compared to the control group, indicating that the combination therapy was effective.
What is Garavishajanit Amlapitta?
Garavishajanit Amlapitta is a digestive disorder related to dietary imbalances, resulting in the vitiation of Pitta dosha, leading to symptoms such as heartburn and indigestion.
What ingredients were used in the trial group treatment?
The trial group was treated with Swarnamakshik Bhasma, Kshaudra, and Sharkara, which are known for their beneficial properties in alleviating symptoms associated with Amlapitta.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Efficacy of swarnamakshik bhasma in garavishjanit amlapitta.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Amlapitta (Amla-pitta):
Amlapitta refers to a digestive disorder characterized by intensified acid production in the stomach, frequently linked to the consumption of inappropriate foods as per Ayurvedic principles, such as Viruddhahar. It presents symptoms like heartburn and dyspepsia, arising from Pitta dosha imbalance and poor digestion, leading to adverse effects on Agni (digestive fire).
2) Sharkara (Sarkara):
Sharkara, or sugar, in Ayurvedic medicine, is recognized for its sweet taste (Madhur Rasa) and cooling properties (Sheet Virya). It plays a role in balancing Pitta dosha, makes medicines more palatable, and aids in digestion. It is considered beneficial for treating various conditions, including Amlapitta, by alleviating vitiated Pitta.
3) Kshaudra (Ksaudra):
Ksaudra is an Ayurvedic term related to sour substances, often included in formulations to enhance digestive and metabolic functions. It is instrumental in mixing with other drugs to facilitate effective therapeutic measures. The study highlights Kshaudra's role within the formulations used to address Amlapitta symptoms.
4) Pitta:
Pitta is one of the three primary doshas in Ayurveda, associated with the elements of fire and water. It governs digestion, metabolism, and transformation processes in the body. When vitiated, Pitta leads to several disorders, including Amlapitta, marked by symptoms like acidity and indigestion, necessitating its regulation for health.
5) Rasa (Rasha):
Rasa, meaning taste or essence in Ayurvedic context, categorizes substances into different flavors that influence health and medicinal properties. The identification of Rasa assists in understanding a substance's effect on the doshas, guiding treatments in a clinical setting. It is vital in formulating drugs, influencing patient therapeutic outcomes.
6) Bhasma (Bhasman):
Bhasma refers to the pharmaceutical form of processed metal or mineral substances in Ayurveda, known for their potent therapeutic properties after undergoing purification and incineration. It is extensively used in various formulations to treat ailments. Swarnamakshik Bhasma, for instance, is highlighted for its efficacy in treating Garavishajanit Amlapitta.
7) Study (Studying):
A study in this context pertains to a systematic investigation aimed at evaluating the clinical efficacy of Swarnamakshik Bhasma with Kshaudra and Sharkara in treating Garavishajanit Amlapitta. This research underscores the scientific approach within Ayurveda, integrating traditional practices with modern clinical methodologies to substantiate treatment effectiveness.
8) Dipika:
Dipika is the name of the lead researcher in the study conducted on the efficacy of Swarnamakshik Bhasma. As an Assistant Professor at Shekhawati Ayurved College, her credentials lend authority to the research. Her insights and interpretations play a crucial role in advancing knowledge surrounding Ayurvedic treatments.
9) Virya:
Virya denotes the energetic property or potency of a substance within Ayurvedic medicine, primarily relating to its effect on bodily functions. Understanding a drug's Virya helps predict its therapeutic effects, such as heating or cooling impact, guiding practitioners in selecting appropriate treatments tailored to individual needs and conditions.
10) Guna:
Guna translates to the inherent attributes or qualities of a substance in Ayurveda that affect its interaction with the body. These qualities determine how a substance behaves when administered, influencing its therapeutic efficacy. Different Guna classifications assist in tailoring Ayurvedic treatments, aiming for overall balance and health.
11) Observation:
Observation refers to the systematic assessment and monitoring of patients during the clinical trial. It involves documenting changes in symptoms and responses to treatments within both control and trial groups. Accurate observation is essential for validating the efficacy of the intervention and drawing meaningful conclusions from the study findings.
12) Avipaka:
Avipaka signifies the condition of undigested or poorly digested food in Ayurvedic terms. It occurs when Agni (digestive fire) is weak, often leading to the outbreak of Amlapitta. Addressing Avipaka is crucial in the treatment of digestive disorders, as strengthening Agni can restore normal digestion and alleviate associated symptoms.
13) Drug:
In this Ayurvedic study, 'drug' refers to the medicinal preparations used, specifically the combination of Swarnamakshik Bhasma with Kshaudra and Sharkara. It emphasizes the importance of utilizing standardized formulations that have undergone rigorous preparation methods to ensure their efficacy and safety in treating conditions like Garavishajanit Amlapitta.
14) Aruci:
Aruchi signifies a lack of appetite or aversion to food, often observed in patients suffering from digestive disorders such as Amlapitta. It indicates an imbalance in the digestive system, pointing towards the need for treatment strategies aimed at restoring balance and enhancing the digestive capacity (Agni) for improved health.
15) Klama:
Klama refers to fatigue or exhaustion that can arise from various causes, including poor digestion or an imbalance in doshas. In the context of the study, it was one of the symptoms evaluated to assess the efficacy of the treatments. The inability of the trial drug to alleviate Klama indicates areas needing further exploration.
16) Agnimandya (Agni-mandya, Agnimamdya):
Agnimandya denotes weak or impaired digestive fire (Agni), crucial in Ayurvedic physiology. It leads to improper digestion, manifesting through symptoms like Amlapitta. Understanding and addressing Agnimandya is essential for restoring health, as enhancing Agni aids in efficient digestion, absorption, and overall wellness.
17) Garavisha (Garavisa, Gara-visha):
Garavisha is a term used to describe toxic substances resulting from incompatible food combinations (Viruddhahar) that disturb the physiological balance. This condition can trigger various ailments, including Garavishajanit Amlapitta. The study focuses on treating symptoms related to Garavisha through specific Ayurvedic formulations aimed at restoring balance.
18) Varanasi (Varanashi):
Varanasi, a significant city in India, is referenced as the origin of many classical Ayurvedic texts and teachings. It signifies the historical depth and cultural roots of Ayurveda. The city plays a pivotal role in the education and dissemination of Ayurvedic knowledge, impacting both practice and philosophy across generations.
19) Vitiation (Vitiated):
Vitiation implies the disruption or alteration of the natural balance within doshas, bodily functions, or elements. Recognizing vitiation is crucial in Ayurvedic diagnosis and treatment, as it informs therapeutic strategies aimed at restoring harmony. The study investigates vitiated Pitta and its correlation with Amlapitta for appropriate interventions.
20) Guru:
Guru conveys heaviness or density concerning dosha characteristics in Ayurveda. Evaluations within the study of symptoms include categorizations of patients based on their physical states. Understanding Guru helps condition-related assessments, particularly regarding symptoms connected to indigestion and metabolic disturbances, common in Amlapitta cases.
21) Kaphapitta (Kapha-pitta):
Kapha-pitta refers to the interaction between the Kapha and Pitta doshas, which can manifest various clinical symptoms when imbalanced. Their combined influence is examined in the study for its role in Amlapitta's etiology. Strategies for treating Kapha-pitta imbalances are crucial for holistic management within Ayurvedic frameworks.
22) Pratishthana (Pratisthana, Pratishthan):
Pratishthan refers to an establishment or foundational basis for Ayurvedic principles and practice. The term embodies the significance of grounding Ayurvedic treatments in tradition and empirical studies, as exemplified in the study assessing Swarnamakshik Bhasma's efficacy, reinforcing the need for scholarly support in therapeutic approaches.
23) Discussion:
Discussion in the research reflects a critical analysis of findings, where outcomes from the clinical trial are evaluated against existing literature, integrating observations, implications of results, and subsequent recommendations. It contributes to the academic dialogue surrounding Ayurvedic practices and helps contextualize the relevance of study outcomes in broader health paradigms.
24) Samprapti:
Samprapti denotes the pathophysiological process that leads to disease formation according to Ayurveda. Understanding the Samprapti of Garavishajanit Amlapitta allows practitioners to trace back the causes of symptoms to identify treatment strategies. It emphasizes the importance of considering a comprehensive approach for effective patient care in Ayurvedic practices.
25) Rajasthan:
Rajasthan, noted for its cultural heritage, is the region where the study’s leading researcher, Dr. Dipika, is positioned as an Assistant Professor in Ayurved. The location reflects the integration of traditional practices within a contemporary academic framework, fostering an environment for Ayurveda research and education to thrive.
26) Amavisha (Amavisa):
Amavisha indicates toxic metabolic products from incomplete digestion due to poor Agni or faulty dietary practices, leading to various disorders. This term is pivotal in Ayurvedic pathophysiology, closely linked with conditions like Amlapitta. The study evaluates how the trial formulations counteract Amavisha effects on health.
27) Samhita:
Samhita refers to collections of ancient texts that codify Ayurveda's principles, theories, and practices. These texts are foundational sources for practitioners, providing guidelines for diagnosis and treatment. The study aligns its findings with classical Samhita references, ensuring that modern applications adhere to traditional Ayurvedic wisdom.
28) Prakrit (Prakrt):
Prakrit pertains to the natural state of elements or qualities in Ayurvedic contexts. The term underscores importance in discerning normal versus pathological changes in bodily functions. Recognizing Prakrit conditions aids in diagnosing and formulating effective treatments, aligning with Ayurvedic principles of balance and health.
29) Disease:
Disease in this context represents the disordered state affecting the natural balance within the body, leading to the manifestation of symptoms. Amlapitta is a specific example where imbalances in doshas lead to digestive disturbances. Understanding disease allows Ayurveda to provide targeted treatments for restoring health.
30) Kapha:
Kapha, one of the three doshas in Ayurveda, embodies earth and water elements, responsible for stability, structure, and lubrication. When vitiated, Kapha can obstruct bodily functions, leading to health complications. The interaction between Kapha and Pitta within the context of Amlapitta is significant for diagnostic processes.
31) Delhi:
Delhi operates as a crucial hub for Ayurvedic education, practices, and research in India, reflecting a blend of traditional knowledge and modern medical inquiry. It fosters a rich academic environment where research like the study on Swarnamakshik Bhasma is conducted, contributing to the expansion of Ayurvedic curriculum and methodologies.
32) Agni:
Agni, or digestive fire, is a foundational concept in Ayurveda that regulates digestion, metabolism, and overall health. A balanced Agni contributes positively to bodily functions while a diminished Agni leads to digestive disorders like Amlapitta. Strengthening Agni is central to treatment strategies in Ayurvedic practice.
33) Aha (Ahan, Ahar):
Ahar, or food, plays a vital role in Ayurvedic health paradigms, emphasizing the importance of diet in maintaining balance among doshas. The right Ahar promotes Agni, fostering proper digestion and wellness. In treating conditions like Amlapitta, Ahar choices are critically evaluated to enhance recovery and health.
34) Raktapitta (Rakta-pitta):
Rakta-pitta signifies a particular condition related to heightened Pitta in the blood that can manifest various symptoms like inflammation and digestion issues. Recognizing Rakta-pitta is essential in diagnosing and treating conditions like Amlapitta. The study observes the interaction of trial drugs within this context for effective remedies.
35) Utklesha (Utklesa):
Utklesha describes the feeling of nausea or queasiness prevalent in digestive disorders. In Ayurvedic terms, it suggests disturbances in the body's internal balance. The study assessed Utklesha as one of the subjective symptoms affected by the trial drug, highlighting its relevance in understanding treatment efficacy in Amlapitta.
36) Bharati:
Bharati here refers to Bharati Vidyapeeth Medical Foundation’s Ayurved Hospital and Research Centre, where the clinical trial was conducted. This institution emphasizes Ayurvedic research and education, providing an infrastructure to explore, validate, and disseminate Ayurvedic knowledge while fostering a holistic understanding of health.
37) Laghuta:
Laghuta denotes lightness in Ayurvedic terms, often associated with health and balanced doshas. Achieving Laghuta is a goal in treating conditions such as Amlapitta, where heavy or dense qualities need to be alleviated. The study emphasizes how trial drugs contribute to this state, fostering digestive comfort.
38) Dravya:
Dravya refers to substances or materials utilized in Ayurvedic formulations. In the context of the study, the specificity of Dravya used, such as Swarnamakshik Bhasma, indicates the focus on quality ingredients that are integral to the efficacy of treatments. Understanding Dravya contributes to improved therapeutic outcomes.
39) Sevana:
Sevana refers to the consumption or ingestion of substances, especially concerning dietary habits in Ayurveda. The study closely examines Sevana patterns related to the consumption of Viruddhahar and its consequences in causing Amlapitta. Addressing Sevana informs treatment approaches toward restoring digestive balance.
40) Mishra (Misra):
Mishra indicates a mixed or combined aspect, particularly within Ayurveda, where different herbs or compounds are employed together for synergistic effects. This can enhance the effectiveness of treatments for conditions like Amlapitta. The study explores such mixtures’ roles, emphasizing the importance of balanced formulations in therapeutic practices.
41) Koshna (Kosna):
Koshna refers to the moderate heating or warmth applied to substances or food items in Ayurvedic practice. It signifies the beneficial effects of warming in promoting digestion and enhancing absorption. The study utilizes Koshna Jala (warm water) to optimize the administration of trial drugs for Amlapitta.
42) Srotas (Shrotas):
Srotas denote the channels or pathways in the body through which substances travel, including nutrients and toxins. Understanding Srotas is crucial in Ayurvedic treatment as it facilitates accurate diagnosis and therapy. In the context of Amlapitta, attention to Srotas can enhance the effectiveness of chosen remedies.
43) Chardi:
Chardi signifies vomiting, a common symptom associated with various gastrointestinal disorders. In the context of Amlapitta, assessing Chardi helps determine the severity of digestive distress. The study evaluates how the trial drug affects symptoms like Chardi, contributing to understanding the treatment's efficacy.
44) Dosha (Dosa):
Dosha represents the fundamental principles of Ayurvedic medicine, pivotal in understanding individual constitutions and health imbalances. The three doshas—Vata, Pitta, and Kapha—form the basis for diagnosing and treating conditions. The study highlights the interplay of doshas, particularly in the context of Amlapitta due to improper dietary behaviors.
45) Rakta:
Rakta refers to the blood element in Ayurveda, associated with nourishment and vitality. The balance of Rakta is critical for overall health, impacting energy levels and bodily functions. The study examines conditions arising from distorted Pitta and their effects on Rakta, emphasizing the importance of maintaining this balance.
46) Mridu (Mrdu):
Mridu denotes gentleness or softness, often in reference to effects or characteristics of treatments in Ayurveda. In the study, Mridu Shodhana (gentle purification) is part of the treatment protocol, where gentle detoxification methods are utilized to prepare patients for more intense therapeutic interventions directed toward resolving issues like Amlapitta.
47) Jirna:
Jirna conveys the meaning of 'old' or 'aged' in the context of digestion and food intake. In Ayurveda, Jirna Ahar refers to food that has been digested properly and is assimilated effectively. The study correlates this concept with trial treatments, aiming to optimize digestion in patients experiencing Amlapitta.
48) Hetu:
Hetu indicates the cause or reason behind an ailment within Ayurvedic explanations. In the context of Amlapitta, identifying Hetu is fundamental in treatment methodology, aligning it with the root causes, such as understanding the implications of consuming Viruddhahar or Incidental toxic food combinations affecting Pitta.
49) Sita (Shita):
Sita refers to the cold quality of substances in Ayurveda, often seen as beneficial for balancing heat-related disorders. In the context of Amlapitta, Sita properties in medicines like Sharkara provide a soothing effect on Pitta, supporting treatment strategies aimed at restoring digestive harmony.
50) Jala:
Jala translates to water in Ayurveda, emphasizing its vital role in sustaining life and health. It is essential for digestion, detoxification, and overall bodily functions. The study utilizes Koshna Jala to aid in the administration of trial medications, reflecting integration of elemental healing in therapeutic practices.
51) Pune:
Pune refers to the city where Bharati Vidyapeeth Medical Foundation’s Ayurved Hospital and Research Centre is located. Known for both its historical importance and modern academic institutions, Pune provides a dynamic environment for Ayurvedic research, being pivotal in advancing studies like the investigation of Swarnamakshik Bhasma's efficacy.
52) Kala:
Kala means time or a specific moment within the Ayurvedic framework. Timing plays a crucial role in determining the effectiveness of administering medicines, particularly in line with Dosha cycles. In the study, consideration of Vyanodan Kala guides when to optimally administer treatments for the best therapeutic outcomes.
53) Food:
Food is a central aspect of Ayurveda, deeply interconnected with health and wellness. The type, quality, and combinations of food consumed influence the balance of doshas. In the study, the impact of Viruddhahar on Amlapitta underscores the significance of healthy food choices in maintaining optimal digestive function and overall health.
54) Line:
Line refers to the treatment regimen or protocol observed in contemporary medical practices. In the context of the study, it highlights a comparison between traditional Ayurvedic formulations and modern symptomatic treatments. Understanding the line of treatment helps in evaluating the efficacy of the trial drug against existing therapeutic standards.
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