Journal name: World Journal of Pharmaceutical Research
Original article title: Plasma cell gingivitis influenced by dietary factors
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Subtitle: an unusual case presentation
Original source:
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Dr. Debarati Bhowmick MDS, Dr. Kushal Chatterjee MDS, Dr. Tanya Khaitan MDS and Dr. Arpita Kabiraj MDS
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Plasma cell gingivitis influenced by dietary factors
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr20175-8388
Copyright (license): WJPR: All rights reserved
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Summary of article contents:
Introduction
Plasma cell gingivitis (PCG) is a rare benign condition that leads to extensive inflammation of the gingiva characterized by a massive infiltration of plasma cells in the connective tissue. Clinically, it presents as erythematous gingivitis, often associated with allergic reactions to various substances, including certain food items and dental products. Understanding the etiology, clinical presentation, and treatment approaches for PCG is essential for effective management and prevention of recurrence.
Allergic Origins of PCG
One of the critical aspects of PCG is its association with allergic reactions to dietary substances. Various allergens, such as those found in common foods like wheat, tomatoes, and brinjal, have been identified as potential triggers. A case report of a 13-year-old female demonstrated this connection, where a thorough examination revealed that her gingivitis was linked to specific food allergies. After identifying the allergens through blood tests, appropriate dietary modifications were recommended, leading to significant improvement in her condition.
Clinical Presentation and Diagnosis
PCG manifests as a severe, diffuse enlargement of the gingiva, with bright red, friable, and edematous characteristics. The condition can often mimic other systemic diseases such as leukemia and lichen planus, making differential diagnosis essential. In clinical examinations, the amount of plaque may be minimal relative to the extent of gingival inflammation, which reinforces the need for careful histopathological investigation. The definitive diagnosis requires an integration of clinical findings and laboratory results to differentiate PCG from other similar conditions.
Treatment Approaches
Effective management of PCG typically involves surgical intervention, particularly in cases of severe gingival enlargement. Procedures like internal bevel gingivectomy have been employed to remove hyperplastic tissue, allowing for histopathological examination. Following surgical treatment, the identification of allergic substances plays a crucial role in preventing recurrence. The patient's follow-up demonstrated no regrowth of gingival tissue when allergens were appropriately avoided post-treatment, affirming the importance of allergen elimination in the management strategy.
Conclusion
PCG is a complex condition that necessitates a thorough understanding of its clinical and histopathological features, as well as its potential allergic origins. Recognition of the disease, accurate diagnosis, and tailored treatment approaches are crucial in managing PCG effectively. With heightened awareness of dietary triggers and diligent follow-up care, patients can achieve long-term remission, reducing the risk of recurrence and improving overall oral health.
FAQ section (important questions/answers):
What is plasma cell gingivitis (PCG) and its characteristics?
PCG is a rare, benign condition characterized by erythematous gingivitis and massive plasma cell infiltration in the connective tissue. Clinically, it presents as diffuse, swollen, and reddened gums with minimal pain and rare ulcerations.
What are the potential causes of plasma cell gingivitis?
The etiology of PCG is thought to be allergic reactions to dental products or dietary factors. Common allergens include flavoring agents, such as cinnamon, and various routine dietary products.
How is plasma cell gingivitis diagnosed?
Diagnosis involves clinical examination, histopathological analysis, and allergy tests. A characteristic biopsy shows plasma cell infiltration, and blood tests can reveal specific allergens related to dietary products.
What treatment options are available for PCG?
Treatment often includes surgical intervention like gingivectomy to remove affected tissue. Additionally, avoidance of identified allergens is crucial for preventing recurrence, and follow-up visits are recommended.
What are the symptoms of PCG in patients?
Patients typically report gum enlargement, especially in the anterior jaw, with bright red, friable, and edematous gingiva. There may be intermittent bleeding, but usually no significant pain.
What is the significance of identifying dietary allergens in PCG?
Identifying and eliminating dietary allergens can lead to remission of PCG. This prevention strategy is essential since ongoing exposure to allergens may lead to recurrence of the condition.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Plasma cell gingivitis influenced by dietary factors”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) India:
India is a South Asian country where the case report of plasma cell gingivitis (PCG) was conducted. Its diverse population and varying diets could influence the prevalence and manifestation of allergic conditions like PCG, emphasizing the need for localized medical research that addresses specific regional dietary factors and health issues.
2) Bengal (Bemgal):
Bengal, a region in Eastern India, is significant as the various medical professionals contributing to this case report are affiliated with institutions located in West Bengal. This geographical context is crucial for understanding local dietary habits and potential allergens linked to oral health, specifically in pediatric patients affected by PCG.
3) Food:
Food is a critical factor influencing plasma cell gingivitis in this case, where dietary items were identified as allergens. The patient’s dietary habits were investigated to determine specific foods that might have triggered the hypersensitive reaction leading to PCG, highlighting the relationship between diet and oral health.
4) Sign:
Sign refers to clinical indicators, such as the negative Nikolsky’s sign observed in this patient. This detail is essential for differentiating PCG from other conditions. The presence or absence of specific signs aids clinicians in diagnosing complex oral diseases and determining appropriate treatment plans for similar cases.
5) Substance:
Substance pertains to the various allergens, including certain dietary products, identified in the patient’s allergy testing. Recognition of these substances is crucial, as eliminating exposure to them is key in the management and remission of plasma cell gingivitis, reflecting the importance of personalized treatment based on specific allergies.
6) Swelling:
Swelling is one of the primary clinical manifestations of plasma cell gingivitis, characterized by diffuse gingival enlargement. The degree and appearance of swelling can help clinicians assess the severity of the condition, guiding further diagnostic procedures and treatment interventions to restore gingival health effectively.
7) Allergy:
Allergy is central to the case report, as the 13-year-old patient exhibited hypersensitivity to several dietary products. Identifying the allergic reaction is essential in diagnosing plasma cell gingivitis, and understanding the allergy helps frame treatment strategies that focus on avoiding specific allergens to prevent recurrence of symptoms.
8) Blood:
Blood tests, specifically for allergen-specific antibodies, play a vital role in diagnosing plasma cell gingivitis in this case. Analyzing blood samples helps establish links between dietary components and allergic reactions, providing valuable information for clinicians to develop an effective treatment protocol for managing the disease.
9) Drug:
Drug history is relevant when diagnosing plasma cell gingivitis, as certain medications can lead to similar gingival enlargements. A thorough review of any drug use is essential to rule out drug-induced gingival hyperplasia, ensuring proper differentiation and diagnosis of PCG as a unique condition.
10) Discussion:
Discussion in the context of this case report encompasses the analysis and interpretation of the findings related to plasma cell gingivitis. It allows the authors to contextualize their observations within existing literature, offering insights into potential causes, treatment options, and the importance of further research in similar cases.
11) Cinnamon:
Cinnamon is highlighted as a potential allergen that may contribute to plasma cell gingivitis. As certain flavoring agents in dietary products, cinnamon’s role as an irritant or allergen supports the notion that specific dietary factors can significantly affect oral health and contribute to conditions like PCG.
12) Bleeding:
Bleeding is mentioned as a symptom related to the gingival condition in the patient. Mild and intermittent blood discharge can indicate inflammation or trauma in the gums and is an important clinical feature that can help differentiate plasma cell gingivitis from other types of gingival diseases.
13) Kalyani (Kalyanin):
Kalyani, a city in West Bengal, India, is referenced as the location of one of the dental institutions involved in the study. This geographical context emphasizes the importance of local healthcare facilities and practitioners in addressing specific regional health issues, including oral diseases like plasma cell gingivitis.
14) Disease:
Disease refers to plasma cell gingivitis itself within the context of this case report. Understanding the characteristics, symptoms, and impacts of this specific disease is necessary for clinicians to formulate effective treatment strategies and enhance patient care while contributing to the broader medical knowledge on gingival conditions.
15) Science (Scientific):
Science underpins the entire study, emphasizing the importance of empirical investigation in diagnosing and treating plasma cell gingivitis. The integration of clinical observation, laboratory testing, and histopathological analysis reflects a scientific approach to understanding the mechanisms and manifestations of this rare gingival condition.
16) Brinjal:
Brinjal, or eggplant, is one of the dietary substances identified as an allergen for the patient diagnosed with plasma cell gingivitis. The recognition of such particular foods reinforces the connection between diet and oral health, indicating the need for tailored dietary recommendations to manage allergic predispositions effectively.
17) Surface:
Surface is relevant when discussing the oral examination findings, particularly regarding the appearance of the gingiva surrounding the maxillary and mandibular teeth. The assessment of the gingival surface helps clinicians appreciate the extent of the condition and aids in planning appropriate surgical and therapeutic interventions.
18) Madhya:
Madhya Pradesh, another state in India, represents the location of one of the medical institutions contributing to the study. The involvement of multiple regions illustrates the collaborative nature of medical research in India and its focus on addressing diverse health issues prevalent in the population.
19) Indore:
Indore, a city in Madhya Pradesh, India, is mentioned as the location of one of the contributors to the case report. The diversity of medical institutions across different locations in India helps in gathering varied clinical experiences, ultimately enriching the study of conditions such as plasma cell gingivitis.
20) Family:
Family history was assessed but found to be negative in this case. This consideration is important in clinical evaluations as it helps determine any genetic or hereditary predispositions to conditions like plasma cell gingivitis, highlighting the need for comprehensive patient histories in diagnostics.
21) Cilli:
Chilli is noted as a potential allergen connected with the patient's plasma cell gingivitis diagnosis. Its inclusion as a dietary factor emphasizes the broader category of common culinary spices that can provoke hypersensitivity reactions, illustrating the complex relationship between diet and oral inflammatory diseases.
22) Pain:
Pain is addressed in the case report, noting that the patient did not experience pain despite the extensive gingival enlargement. This lack of pain can sometimes complicate diagnosis, as it differs from many other gingival conditions that typically involve discomfort, thus requiring careful evaluation by clinical professionals.
23) Post:
Post refers to the postoperative phase after the surgical intervention performed on the patient. Monitoring and follow-up during this phase are crucial for assessing healing and preventing recurrence of plasma cell gingivitis, ensuring that the surgical procedure was effective in managing the condition.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Plasma cell gingivitis influenced by dietary factors’. Further sources in the context of Science might help you critically compare this page with similair documents:
Differential diagnosis, Surgical intervention, Clinical presentation, Dietary factor, Hypersensitivity reaction, Histopathological analysis, Immune Reaction, Oral pathology, Plasma cell gingivitis, Gingival enlargement, Dental college, Serologic testing.