Microbial evaluation of a marketed herbo-mineral formulation tribhuvan kirti ras
Journal name: World Journal of Pharmaceutical Research
Original article title: Microbial evaluation of a marketed herbo-mineral formulation tribhuvan kirti ras
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Dr. Sheelpriya R. Walde and Dr. R. Rachana Devendra
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World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Microbial evaluation of a marketed herbo-mineral formulation tribhuvan kirti ras
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr20175-8440
Copyright (license): WJPR: All rights reserved
Summary of article contents:
Introduction
Ayurvedic herbal and herbomineral products, like Tribhuvan Kirti Ras, have been utilized for centuries in the treatment of various ailments. A World Health Organization (WHO) survey highlights that 70-80% of the global population, particularly in developing regions, relies on herbal remedies for primary healthcare. Despite the accessibility and affordability of these products compared to synthetic drugs, concerns about microbial contamination persist, as it can diminish their therapeutic efficacy and lead to adverse health effects. This study aimed to evaluate the microbial contamination in commercial samples of Tribhuvan Kirti Ras and compare the findings with WHO microbiological standards.
Significance of Microbial Quality in Herbal Products
The quality of herbal medicines is significantly influenced by microbial contamination, which can arise from various environmental factors such as temperature, humidity, and post-harvest handling. The presence of bacteria, fungi, and their by-products can not only spoil the herbal products but also lead to safety concerns for consumers. The study emphasizes that microbiological testing is essential for assessing the safety and efficacy of herbal formulations. Standardizing and monitoring the microbial load is crucial for ensuring that products meet the recommended limits set by health authorities, primarily to safeguard public health and maintain the integrity of herbal medicines.
Findings of Microbial Contamination
The study found that all three tested samples of Tribhuvan Kirti Ras exhibited bacterial and fungal contamination. The total viable aerobic counts (TVAC) were within acceptable limits according to WHO standards; however, the presence of pathogenic bacteria such as E. coli, along with fungal species like Gliocladium, Papulospora, Geomyces, and Rhizopus, raised significant concerns. These contaminations imply that the manufacturing processes and storage practices currently in place may not adequately protect these products from microbial invasion, underscoring the need for stricter quality control measures.
Sources of Contamination
Microbial contamination can occur at various stages, from raw material sourcing to processing and packaging. Factors such as environmental exposure during harvesting, improper storage conditions, and inadequate hygiene practices during manufacturing can introduce harmful microorganisms into herbal products. Additionally, the study suggests that the use of contaminated water during the preparation of herbal formulations and prolonged exposure to moisture or unsanitary surfaces can facilitate microbial growth. Therefore, recognizing and addressing these risks is critical for ensuring the safety and efficacy of herbal medicines.
Conclusion
The findings from the assessment of microbial contamination in Tribhuvan Kirti Ras underscore the importance of stringent quality control measures in the production of herbal products. Although the total viable aerobic counts were acceptable, the detection of pathogenic bacteria such as E. coli and various fungi indicates significant areas for improvement. To enhance product safety, manufacturers should adopt Good Manufacturing Practices (GMP) and invest in better hygiene protocols throughout the production chain. Comprehensive studies are warranted to further investigate and mitigate microbial risks, ensuring that Ayurvedic formulations remain safe and effective for public use.
FAQ section (important questions/answers):
What is the purpose of the study on Tribhuvan Kirti Ras?
The study aims to evaluate microbiological contamination in commercially available Tribhuvan Kirti Ras and compare the findings against WHO standards for herbal preparations.
What were the main types of microbial contamination found?
The study identified contamination from both Gram-positive and Gram-negative bacteria, as well as various fungal species including Gliocladium, Papulospora, Geomyces, and Rhizopus.
How does microbial contamination affect herbal products?
Microbial contamination can reduce the therapeutic activity of herbal products, cause spoilage, lead to infections, and alter the pharmacological properties of the medications.
What were the total viable aerobic counts in the samples?
The total viable aerobic count (TVAC) was found to be 9.3×10^4, 4.5×10^4, and 5.8×10^4 CFU/g across the three tested samples.
What are the precautions suggested to prevent contamination?
The study recommends good hygiene practices, staff training in Good Manufacturing Practices (GMP), and clean packaging materials to reduce microbial contamination in herbal products.
Why is E. coli presence concerning in herbal formulations?
E. coli contamination indicates potential fecal contamination, which raises safety concerns. Some E. coli strains can cause serious illness, emphasizing the need for strict microbiological control.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Microbial evaluation of a marketed herbo-mineral formulation tribhuvan kirti ras”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Kirti (Kirtti):
The term 'Kirti' refers to a reputation or fame, often associated with the attributes or successes of the item or individual in context. In the context of herbal formulations like 'Tribhuvan Kirti Ras', it signifies the recognition and acceptance of the formulation in Ayurvedic medicine. The 'Kirti' embodied in such formulations reflects their therapeutic efficacy and historical usage in traditional healing practices.
2) Medicine:
The word 'Medicine' pertains to substances or treatments utilized for preventing, diagnosing, treating, and healing health ailments. In this context, it emphasizes the herbo-mineral formulations like 'Tribhuvan Kirti Ras' intended to address respiratory infections and fever. Understanding medicine's role in traditional practices underscores the significance of both efficacy and safety in healing modalities.
3) Quality:
The term 'Quality' embodies the degree of excellence inherent in a product, highlighting critical attributes like purity, efficacy, and safety. In the context of the study, the quality of 'Tribhuvan Kirti Ras' is examined in relation to microbial contamination. Adhering to quality standards is essential for ensuring the therapeutic potential of herbal medicines.
4) Table:
In scientific studies, a 'Table' refers to a structured arrangement of data that facilitates visualization and comprehension of results. It is crucial for summarizing findings, such as microbial counts or test results in the study. Using tables allows researchers and readers to extract essential information efficiently, enabling better understanding and comparison of data collected.
5) Aureus:
'Aureus' refers to 'Staphylococcus aureus', a significant bacterial species often implicated in infections. Its presence in herbal products indicates potential contamination, which raises safety concerns for consumers. Identifying 'S. aureus' in 'Tribhuvan Kirti Ras' signals the necessity for rigorous quality control measures in its production, emphasizing the importance of monitoring microbial levels.
6) Medium:
The term 'Medium' pertains to the environment or substrate in which organisms, such as bacteria and fungi, grow and are assessed in laboratory settings. In microbial evaluation, different media are tailored to promote the growth of specific organisms, such as agar plates. The choice of medium influences the effectiveness and accuracy of microbial count and identification.
7) Species:
'Species' denotes distinct groups of organisms that share common characteristics and can interbreed. In this context, recognizing various bacterial and fungal species in the microbiological profile of 'Tribhuvan Kirti Ras' is paramount for assessing contamination levels. Understanding species diversity aids in evaluating the potential health risks associated with contaminated herbal preparations.
8) Water:
The term 'Water' is essential in medicinal preparation, serving as a solvent or medium for extraction processes. In the study, water quality is scrutinized to determine its role in potential microbial contamination of formulations. Impurities in water can introduce harmful microorganisms, emphasizing its critical importance in maintaining the safety of herbal medicines.
9) Study (Studying):
'Study' signifies the rigorous investigation and analysis conducted to evaluate specific phenomena, in this case, the microbial quality of 'Tribhuvan Kirti Ras'. The outcomes of the study contribute valuable insights into the safety and efficacy of herbal formulations, guiding both practitioners and manufacturers in fostering higher standards in herbal medicine production.
10) Drug:
The word 'Drug' encompasses any substance intended for use in the diagnosis, cure, treatment, or prevention of disease. In Ayurvedic context, drugs may encompass herbal formulations, where understanding their therapeutic utility is essential. Evaluating aspects such as microbial contamination also aligns with ensuring drugs' safety, effectiveness, and adherence to therapeutic claims.
11) Bhasma (Bhasman):
'Bhasma' refers to an ash obtained from calcined minerals or metals, used in various Ayurvedic formulations. It plays a significant role in enhancing the therapeutic efficacy of medications like 'Tribhuvan Kirti Ras'. Exploring the considerations regarding 'Bhasma' involves understanding its preparation, quality standards, and implications for product safety.
12) Nagapura (Naga-pura):
Nagpur is a city in Maharashtra, India, recognized for its educational and traditional medicinal expertise. The study of 'Tribhuvan Kirti Ras' was conducted in Nagpur, emphasizing the local practices and formulations of Ayurveda. The city's role highlights the cultural and historical significance tied to herbal medicine preparation and consumption in the region.
13) Tvac:
Total viable aerobic count (TVAC) is a microbiological measure reflecting the number of viable microorganisms in a sample. In the study, TVAC levels were analyzed to determine the microbial quality of 'Tribhuvan Kirti Ras'. This metric guides adherence to safety standards, reinforcing the importance of monitoring microbial contamination in medicinal products.
14) Soil:
The term 'Soil' is vital as it serves as the natural habitat for numerous microorganisms, including pathogens. Contamination from soil can affect the quality of herbal raw materials used in 'Tribhuvan Kirti Ras'. Understanding the implications of soil-derived microbes assists in establishing contamination sources and is crucial for enhancing manufacturing hygiene.
15) Nature:
The term 'Nature' encompasses the inherent characteristics and attributes of living organisms and environments. In the context of herbal medicines, nature reflects the selection of plants utilized for their medicinal properties. Recognizing nature's influence helps understand the therapeutic efficacy while considering environmental factors affecting microbial loads in preparations.
16) Activity:
Activity pertains to the functional properties or effects of medicinal substances in treating health conditions. In the assessment of 'Tribhuvan Kirti Ras', understanding the active ingredients and their therapeutic actions is crucial to evaluate its efficacy. The relationship between microbial contamination and activity illustrates the need for quality assurance in herbal formulations.
17) Hygiene (Hygienic):
Hygiene signifies practices aimed at maintaining health and preventing disease, especially related to cleanliness during production and handling of herbal products. The study emphasizes the importance of hygiene protocols to minimize microbial contamination in 'Tribhuvan Kirti Ras'. Ensuring hygiene is vital for both consumer safety and maintaining the integrity of Ayurvedic formulations.
18) Surface:
The term 'Surface' refers to the outer layer of an object where contamination can occur. In the preparation of herbal medicines, the surface of raw materials may carry pathogens, impacting product safety. Proper handling and cleaning of surfaces is pivotal in reducing microbial exposure during manufacturing and throughout the usage of herbal drugs.
19) Harvesting (Harvest):
'Harvest' signifies the collection of herbal plants used in medicine, a crucial step that significantly impacts product quality. The timing and method of harvesting can affect contamination levels and the overall integrity of raw materials used in formulations like 'Tribhuvan Kirti Ras'. Effective harvesting practices are essential to ensure the safety and effectiveness of herbal drugs.
20) Container:
The term 'Container' signifies the vessels used for storing or transporting raw materials and finished herbal products. The safety and cleanliness of containers directly influence the microbial quality of products. Utilizing sterile and clean containers ensures that herbal formulations are protected against microbial contamination, crucial for maintaining their potency and safety.
21) Disease:
The term 'Disease' refers to health disorders that impact well-being and normal function. 'Tribhuvan Kirti Ras' is prescribed for ailments such as respiratory infections and fever. Understanding the types of diseases targeted by such herbal formulations highlights their intended therapeutic benefits while emphasizing the importance of maintaining quality standards in herbal preparation.
22) Mineral:
'Mineral' refers to naturally occurring inorganic substances that often play essential roles in herbal formulations, such as 'Tribhuvan Kirti Ras'. Minerals, including metals like mercury, are considered in Ayurvedic medicine for their purported health benefits. Understanding mineral content and safety assessments are crucial for ensuring the efficacy and safety of mineral-containing preparations.
23) India:
India is recognized for its rich heritage in traditional medicine, particularly Ayurveda. The referenced research is based on the evaluation of herbal formulations like 'Tribhuvan Kirti Ras' within the Indian context. The country's extensive herbal knowledge underscores the importance of conducting rigorous assessments of its herbal products to ensure therapeutic safety and efficacy.
24) Glass:
The term 'Glass' pertains to the material commonly used in laboratory settings for storing and handling samples. Ensuring that glassware is sterile is crucial to prevent contaminant introduction during microbiological evaluations. The study emphasizes the role of sterile glass containers in safeguarding the integrity and reliability of the microbial assessments conducted on herbal products.
25) Bile:
'Bile' refers to a digestive fluid produced by the liver. In the context of microbiological tests, bile salts are used in media to select for Gram-negative bacteria, aiding in the identification of organisms like 'E. coli'. The presence of bile in culture media underscores the connection between microbiological testing and understanding the growth of enteric pathogens.
26) Piper longum:
'Piper longum', known as long pepper, is one of the traditional medicinal herbs used in formulation such as 'Tribhuvan Kirti Ras'. This herb is valued for its potential therapeutic properties in enhancing respiratory health. Understanding its role in formulations emphasizes the need for microbiological evaluation to mitigate contamination risks associated with herbal components.
27) Pharmacological:
The term 'Pharmacological' relates to the properties and effects of drugs in treating diseases. In the study's context, assessing the pharmacological actions of components in 'Tribhuvan Kirti Ras' is significant to delineate its therapeutic effects. Understanding pharmacological principles is essential in developing and evaluating the efficacy of herbal medicinal products used in Ayurvedic practices.
28) Maharashtra (Maharastra, Maha-rashtra):
Maharashtra is a state in India where the study of 'Tribhuvan Kirti Ras' was conducted. Recognizing the cultural and geographical context enhances insights into the usage and preparation of Ayurvedic medicines. The state's diverse herbal practices emphasize the need for research to ensure the microbial safety of traditional medicines utilized by the population.
29) Observation:
The term 'Observation' signifies the act of monitoring and assessing conditions or phenomena. In the context of the study, careful observation of microbial levels in 'Tribhuvan Kirti Ras' is crucial for ensuring safety and quality control. Observational studies inform best practices and standards required for manufacturing safe Ayurvedic formulations.
30) Discussion:
'Discussion' refers to the interpretation and analysis of findings derived from research. In the context of evaluating 'Tribhuvan Kirti Ras', it encompasses the critical assessment of microbial contamination, quality issues, and safety implications for consumers. The discussion forms a vital part of scientific communication, elucidating the significance of study results and recommendations for practice.
31) Substance:
The term 'Substance' refers to any material with a defined composition. In herbal medicine, substances might include the raw materials and active ingredients found in formulations like 'Tribhuvan Kirti Ras'. Understanding the properties of these substances is vital to establishing safety profiles and ensuring that the therapeutic claims associated with the herbal products are substantiated.
32) Hingula (Himgula):
'Hingula', or purified cinnabar, is a key herbo-mineral ingredient in 'Tribhuvan Kirti Ras'. It is recognized for its purported therapeutic benefits but carries toxicity concerns. This necessitates stringent quality control and safety assessments to ensure its safe inclusion in Ayurvedic formulations. Understanding the role of 'Hingula' is crucial for evaluating both efficacy and safety.
33) Shuddha (Suddha):
'Shuddha' translates to 'purified' in English and reflects the significance of purification processes in preparing herbo-mineral formulations. In the context of the study, understanding the extent of purification of ingredients like 'Shuddha Hingula' is essential for ensuring safety and efficacy in manufacturing 'Tribhuvan Kirti Ras', emphasizing adherence to traditional preparation methods.
34) Company:
The term 'Company' pertains to the manufacturers of herbal products like 'Tribhuvan Kirti Ras'. Examining the practices and standards of these companies is vital for ensuring compliance with quality regulations. Understanding company accountability emphasizes the importance of transparency and ethical practices in ensuring consumer safety and trust in herbal formulations.
35) Purity:
The term 'Purity' denotes the absence of contaminants and is vital in assessing the quality of herbal medicines. For 'Tribhuvan Kirti Ras', purity ensures that the therapeutic properties are intact without harmful microbial load. Evaluating the purity levels in herbal products underscores the necessity of maintaining stringent quality control standards.
36) Insect:
'Insect' reflects potential contaminants that can compromise the quality and safety of herbal preparations. The presence of insects during harvesting or storage can introduce pathogens, affecting the overall microbial quality of products like 'Tribhuvan Kirti Ras'. Understanding insect-related contamination highlights the importance of hygiene practices throughout the manufacturing process.
37) Sugar:
The term 'Sugar' can serve as a nutrient source for microbial growth, particularly during storage conditions that lack proper control. In herbal medicine, high sugar content in herbal preparations could influence the microbial load in the products. Recognizing these interactions is essential for developing effective preservation strategies for herbal medicines.
38) Fever:
The term 'Fever' is a common health condition characterized by an increase in body temperature, often indicating an underlying infection. 'Tribhuvan Kirti Ras' is specifically formulated to treat fever, highlighting its significance in herbal medicine. Understanding its applications in managing fever reinforces the need for safety assessments and quality controls in its preparation.
39) Shri (Sri, Sr):
The term 'Shri' is a respectful prefix often used in Indian languages, denoting honor or reverence. In the context of 'Shri Ayurved Mahavidyalaya', it highlights the esteemed nature of the institution involved in the study. This acknowledgment signifies the traditional and cultural aspects underpinning Ayurvedic practices, which are integral to the development and evaluation of herbal formulations.
40) Dish (Dis):
The term 'Dish' can refer to the container in which food is served but in scientific contexts, it usually signifies petri dishes used for microbial cultures. In the study, using appropriate dishes for growing microbial colonies is crucial for accurate assessments. Understanding the significance of the dish used reflects the meticulous nature of laboratory protocols in research.
41) Life:
The term 'Life' is fundamental as it refers to the biological existence of organisms, including those studied in microbiological evaluations. In the context of 'Tribhuvan Kirti Ras', understanding life in terms of microbial interactions and the effect of contamination on human health emphasizes the importance of maintaining the safety and efficacy of herbal medicines.
42) Ocimum sanctum:
'Ocimum sanctum', commonly known as holy basil or Tulsi, is an integral herb in Ayurveda with numerous health benefits. Its inclusion in formulations like 'Tribhuvan Kirti Ras' enhances the therapeutic profile of the product. Evaluating the quality and microbial contamination of such culturally significant ingredients is essential to ensure their beneficial effects on health.
43) Transformation (Transform, Transforming):
The term 'Transformation' signifies the process of change, especially in chemical or biological contexts. In herbal formulations, transformation refers to how active compounds can be altered during preparation and formulation processes. Understanding these transformations can provide insights into the efficacy of compounds and the influence of microbial contamination on herbal medicine potency.
44) Purification:
'Purification' pertains to the processes employed to remove contaminants from raw materials, enhancing their safety and efficacy. In Ayurvedic formulations like 'Tribhuvan Kirti Ras', purification is central to ensuring that potentially harmful substances, such as heavy metals, are eliminated. Through effective purification processes, the integrity and therapeutic value of the medicine can be preserved.
45) Performance:
The term 'Performance' refers to the effectiveness or efficiency of a medicinal product in achieving its therapeutic goals. For 'Tribhuvan Kirti Ras', performance is closely linked to its efficacy in treating respiratory diseases. Evaluating performance includes assessing microbial contamination levels, which can significantly influence clinical outcomes and patient safety.
46) Reliability:
The term 'Reliability' indicates the consistency and dependability of a product's performance over time. In the context of herbal medicines, ensuring reliability in formulations like 'Tribhuvan Kirti Ras' is essential for consumer trust. Rigorous testing for microbial contamination and adherence to quality standards contribute to reliability, reinforcing the credibility of Ayurvedic products.
47) Vatsanabha (Vatsa-nabha):
'Vatsanabha', or Aconitum ferox, is a potent herb traditionally used in Ayurvedic medicine. Its presence in formulations signifies its role in treating ailments but also necessitates careful handling due to toxicity concerns. Evaluating the safety and quality of 'Vatsanabha' within 'Tribhuvan Kirti Ras' is crucial to ensuring therapeutic efficacy while mitigating potential health risks.
48) Developing:
The term 'Developing' refers to the process of growth or advancement, particularly in the context of medical practices or products. As Ayurvedic medicine continues to gain popularity globally, developing strategies to ensure the microbial quality and safety of herbal products like 'Tribhuvan Kirti Ras' is critical. This includes research and implementation of best practices in manufacturing.
49) Dhattura:
'Dhattura', or Datura metel, is a plant known for its psychoactive properties and is used cautiously in Ayurveda due to its toxicity. Its inclusion in formulations like 'Tribhuvan Kirti Ras' necessitates a stringent assessment of safety and quality. Understanding its pharmacological implications ensures the responsible use of such potent herbal ingredients.
50) Relative:
The term 'Relative' refers to a contextual relationship or comparison between entities. In evaluating herbal products, establishing the relative effectiveness and safety of traditional formulations like 'Tribhuvan Kirti Ras' compared to modern medicines underscores the dynamics of health practices. Understanding these nuances aids in appreciating the role of herbal medicine within broader health paradigms.
51) Sweating (Sweat):
The term 'Sweating' refers to a physiological response often induced by fever or exercise, which can also relate to the therapeutic action of certain medicines. In Ayurvedic formulations like 'Tribhuvan Kirti Ras', the ability to induce sweating is valuable for managing fevers. Understanding this function emphasizes the herbal medicine's mechanism of action in traditional therapies.
52) Pippali (Pippalin):
'Pippali', or long pepper, is a well-known ingredient in Ayurvedic medicine recognized for its health benefits, particularly in respiratory issues. Its inclusion in formulations necessitates thorough evaluation for microbial contamination. Understanding 'Pippali's' effects and quality ensures that its potential therapeutic benefits are preserved in products like 'Tribhuvan Kirti Ras'.
53) Bhavana (Bha-vana):
'Bhavana' refers to the process of incorporating liquids, such as juices, into powders during Ayurvedic preparation to enhance therapeutic properties. In 'Tribhuvan Kirti Ras', the use of 'Bhavana' with ingredients underscores the delicate balance required for achieving optimal efficacy while highlighting the need for safeguarding against microbial contamination in herbal formulations.
54) Tankana (Tamkana):
'Tankana', or borax, is utilized in Ayurvedic formulations for its purported therapeutic properties. Its inclusion in 'Tribhuvan Kirti Ras' exemplifies the traditional approach of herbo-mineral formulations. Rigorous quality assessments are pivotal to ensure safety profiles consider the potential toxicity and microbial contamination associated with ingredients like 'Tankana'.
55) Account:
The term 'Account' in research refers to a detailed report or documentation of findings. In the context of the study, providing a thorough account of microbial content in 'Tribhuvan Kirti Ras' is essential for establishing the safety and efficacy of herbal products. Such accounts facilitate informed decision-making for practitioners and consumers regarding healthcare options.
56) Dravya:
The term 'Dravya' translates to 'substance' in Ayurveda and refers to the medicinal materials used in formulations. Understanding the properties and quality of 'Dravya' ensures that herbal preparations like 'Tribhuvan Kirti Ras' maintain their intended therapeutic effectiveness. Discussing 'Dravya' links the traditional knowledge with the scientific evaluation necessary for quality assurance.
57) Tulasi:
'Tulasi', or holy basil, is an important herb in Ayurveda known for its health benefits, especially in respiratory ailments. Its incorporation into 'Tribhuvan Kirti Ras' underscores its therapeutic utility. Evaluating the microbial safety of such revered herbs is crucial to maintaining the tradition's integrity and ensuring patient safety.
58) Tankan:
'Tankan', or borax, is a mineral employed in various Ayurvedic formulations. Its role in 'Tribhuvan Kirti Ras' is to provide specific therapeutic properties or to aid in preparation processes. Thorough examinations are necessary to evaluate the benefits and safety of 'Tankan', ensuring microbial safety in herbal medicine formulations.
59) Family:
The term 'Family' in a biological context refers to a grouping of related organisms that share common characteristics. Understanding microbial families present in 'Tribhuvan Kirti Ras' informs about potential contamination risks. This awareness is crucial to employing best practices in manufacturing and ensuring the safety of herbal preparations.
60) Animal:
The term 'Animal' may refer to sources of microbial contamination concerning herbal products. Animal vectors or byproducts can introduce pathogens into herbal formulations like 'Tribhuvan Kirti Ras'. Understanding animal interactions during the herbal product lifecycle underscores the necessity of implementing stringent hygienic practices to mitigate contamination risks.
61) Patra:
'Patra' refers to leaves in Ayurvedic terminology, often used for therapeutic purposes. In 'Tribhuvan Kirti Ras', ingredients like 'Tulsi Patra' contribute to the overall efficacy of the formulation. Evaluating the quality and potential contamination of plant materials emphasizes the need for adhering to safety standards in herbal medicine preparation.
62) Bilva (Vilva):
'Bilva', or Aegle marmelos, is often utilized in Ayurvedic remedies for its reputed health benefits, particularly in digestive disorders. Its incorporation into formulations like 'Tribhuvan Kirti Ras' underscores the importance of assessing microbial safety during preparation. Evaluating 'Bilva's' role ensures that the desired therapeutic effects are delivered without compromising safety.
63) Tulsi:
The word 'Tulsi' pertains to holy basil, a revered herb in Ayurveda known for its extensive medicinal properties. It plays a significant role in the formulation of products like 'Tribhuvan Kirti Ras'. Understanding the role of 'Tulsi' in these compositions emphasizes its therapeutic potentials while also recognizing the importance of microbial quality during its preparation.
64) Honey:
'Honey' is a natural substance with numerous health benefits, often used as an ingredient in Ayurvedic formulations. Its role in 'Tribhuvan Kirti Ras' showcases its ability to enhance flavor and therapeutic properties. Ensuring the microbial safety of honey is essential to maintain the integrity and effectiveness of herbal medicine preparations.
65) Borax:
'Borax', scientifically known as 'Tankana', is a mineral used historically in Ayurvedic medicine. Its role in 'Tribhuvan Kirti Ras' signifies its multifunctional utility, but also necessitates careful evaluation for purity and contamination. Understanding 'Borax's' application in formulations emphasizes the need for safe manufacturing practices to protect consumer health.
66) Soya:
'Soya' refers to soybean, often used in various digestion media for microbiological assessments. Its presence in the formulation process underlines the importance of using appropriate cultures for testing microbial viability. Understanding the media components like 'Soya' ensures the validity and accuracy of microbial testing performed on herbal products.
67) Pose:
The term 'Pose' can refer to presenting or offering a situation that requires assessment. In the study, the presence of microbial contamination poses concerns for 'Tribhuvan Kirti Ras'. Addressing these concerns proactively is crucial for ensuring the safety and quality of Ayurvedic products, influencing consumer trust and therapeutic outcomes.
68) Hand:
The term 'Hand' signifies the role of human actions in the preparation and handling of herbal medicines. In the context of microbial contamination, human hand cleanliness is pivotal to preventing unwanted organisms from entering products like 'Tribhuvan Kirti Ras'. Promoting hygienic practices is fundamental for achieving product safety and integrity in herbal medicine.
69) Post:
The term 'Post' refers to the period following an event or process. In a research context, post-manufacturing practices involve the consideration of contamination risks associated with storage or handling of herbal products. Proper post-production care is essential to maintain the integrity and quality of formulations like 'Tribhuvan Kirti Ras', preventing microbial growth.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Microbial evaluation of a marketed herbo-mineral formulation tribhuvan kirti ras’. Further sources in the context of Science might help you critically compare this page with similair documents:
Environmental factor, Quality Control, Herbo-mineral formulation, Microbial Contamination, Therapeutic Activity, Good Manufacturing Practice, Pharmacological action, Gram-positive and Gram-negative bacteria, Total viable aerobic count, Ayurvedic herbal medicine, Bacterial endospores, Microbiological quality, Microbial evaluation, Tribhuvan Kirti Ras, Microbiological Standards, Good Hygiene Practices, Procurement of Raw Materials, Storage condition.