Deep vein thrombosis (dvt); a case study
Journal name: World Journal of Pharmaceutical Research
Original article title: Deep vein thrombosis (dvt); a case study
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Dr. Minal M. Khode, Dr. Snehal A. Ingle, Dr. Ashish Thatere, Dr. J. D. Gulhane, Dr. P. R. Kabra
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Deep vein thrombosis (dvt); a case study
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr20178-9086
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Summary of article contents:
Introduction
Deep vein thrombosis (DVT) is a serious medical condition characterized by the formation of a blood clot within a deep vein, predominantly occurring in the legs. This case study highlights the treatment journey of a 45-year-old male patient diagnosed with DVT in the left external iliac vein ensuing from a history of trauma. The patient's condition had progressively worsened over 1½ years despite modern medical treatments, prompting his consultation with Ayurvedic practitioners for alternative management. The Ayurvedic approach aligns DVT with the concepts of Siraj Vata and Siraj Granthi, which correspond to the disturbed state of blood and nerve pathways.
The Ayurvedic Perspective on DVT: Siraj Vata and Siraj Granthi
In Ayurveda, DVT is related to Siraj Vata and Siraj Granthi, indicating a disturbance in the flow of blood (Rakta) and an obstruction within the veins (Sira). The patient's condition involved vitiated Vata and Rakta, leading to complications associated with poor circulation. Ayurvedic texts highlight the importance of balancing these doshas through specific management protocols. Treatments such as Jalaukavacharan (leech therapy) and Virechan (therapeutic purging) were incorporated, targeting the underlying derangement of Vata and Rakta to restore normalcy.
Treatment Modalities: Jalaukavacharan and Virechan
Jalaukavacharan was utilized as a primary intervention to alleviate severe pain and manage edema in the left leg. The application of leeches significantly reduced the patient's pain and promoted better circulation. Following this, Virechan was administered, which involved a careful purging process using specific herbal preparations. This approach aimed to eliminate the accumulated toxins and reinstate balance among the doshas. Both methods reflect a holistic view of treatment, focusing on the rejuvenation of bodily functions and enhancing the recovery of the affected venous structures.
Monitoring and Results
Throughout the treatment, the patient's progress was meticulously monitored through girth measurements of the left leg and assessments of clinical symptoms. Significant reductions in leg swelling and pain were documented, demonstrating the efficacy of Ayurvedic management. Venous Doppler studies showed remarkable improvements, including partial recanalization of previously obstructed veins and a decrease in thrombus burden. These outcomes underline the potential of integrating traditional Ayurvedic therapies with contemporary medical practices for better patient care.
Conclusion
The case study illustrates the promising results of Ayurvedic management in treating Deep Vein Thrombosis, particularly in patients unresponsive to conventional therapies. Techniques such as Jalaukavacharan and Virechan align well with addressing the core imbalances in Vata and Rakta, demonstrating a patient-centered approach to healthcare. Future studies with larger sample sizes may further validate these findings and explore the role of Ayurveda in managing recurrent DVT cases while providing a complementary perspective to conventional treatment strategies.
FAQ section (important questions/answers):
What is Deep Vein Thrombosis (DVT) and who is affected?
DVT is the formation of a blood clot in deep veins, typically in the legs. It's common in older adults and can arise from surgery, pregnancy, trauma, or certain health conditions.
How is DVT diagnosed and confirmed?
DVT is diagnosed using Venous Doppler ultrasound, which visualizes blood flow. The diagnosis can reveal the presence of thrombus and assess the extent of any occlusion in the deep veins.
What are the modern treatment options for DVT?
Modern medicine primarily treats DVT with anticoagulants to prevent clotting. Other treatments may include compression stockings and lifestyle changes to reduce risk factors and complications.
How does Ayurveda approach DVT treatment?
In Ayurveda, DVT correlates with conditions like Siraj Vata. It is treated with techniques such as Jalaukavacharan (leech therapy) and Virechana (purgation) to balance bodily doshas.
What were the significant outcomes of the Ayurvedic treatment in the case study?
Ayurvedic management, including Jalaukavacharan and Virechana, led to significant recovery. Clinical assessments showed improved leg girth, reduced pain, and increased mobility for the patient.
What is the importance of Virechana in Ayurveda?
Virechana is a vital Ayurvedic detoxification procedure that helps remove toxins. It supports the treatment of conditions linked with excess Pitta and Rakta dosha, which are relevant in DVT.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Deep vein thrombosis (dvt); a case study”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Rakta:
Rakta refers to blood in Ayurveda, representing one of the vital dhatus (tissues) essential for life. It plays a significant role in nourishing and sustaining bodily functions. Disruption or vitiation of Rakta can lead to various health issues, including conditions like DVT, where blood clotting occurs.
2) Table:
In the context of medical studies, a table serves as a structured representation of data, making it easier to compare observations and results. It allows for a clear visualization of treatment effects, measurements, and patient progress, which is crucial in documenting clinical outcomes and research findings.
3) Vata:
Vata is one of the three doshas in Ayurveda, associated with the elements of air and space. It governs movement and communication within the body. Imbalances in Vata can lead to various health problems, including pain, dryness, and circulatory issues, making its regulation pivotal in treatments.
4) Sanskrit:
Sanskrit is an ancient Indo-Aryan language of India, revered for its historical significance and usage in spiritual texts, including Ayurvedic scriptures. Many Ayurvedic terms, concepts, and treatments are derived from Sanskrit, making it essential for understanding traditional medical literature and practices.
5) Blood:
Blood is a vital fluid responsible for transporting oxygen, nutrients, hormones, and waste products throughout the body. In cases of medical conditions like DVT, the formation of clots within the blood vessels can lead to severe complications, highlighting the need for effective management of blood-related disorders.
6) Varanasi (Varanashi):
Varanasi, a city in India, holds historical and spiritual significance. It is associated with various Ayurvedic traditions and practices. Its cultural heritage encompasses a diversity of healing arts and wellness approaches, contributing to the broader understanding of Ayurveda in Indian healthcare.
7) Granthi (Gramthi):
Granthi refers to nodules or lumps in Ayurveda, which can signify blockages in the body's channels or vessels. Conditions like DVT can be correlated with Granthi, emphasizing the need for techniques that purify and restore proper flow within the circulatory system.
8) Nagapura (Naga-pura):
Nagpur is a major city in central India, known for its educational institutions, including those offering Ayurvedic studies. The city's healthcare facilities play an essential role in providing Ayurvedic treatments, research, and disseminating knowledge about traditional practices to the local population.
9) Pitta:
Pitta is another of the three doshas in Ayurveda, associated with the elements of fire and water. It governs digestion, metabolism, and energy production. Imbalances in Pitta can lead to various medical conditions, including inflammatory disorders, underscoring its importance in treatment approaches.
10) Pratishthana (Pratisthana, Pratishthan):
Pratishthan refers to the establishment or foundation of knowledge or practice, often used in the context of Ayurvedic studies. It symbolizes the principles and guidelines that form the basis of Ayurvedic medicine and treatment methodologies, anchoring them in traditional wisdom.
11) Agnivesha (Agnivesa, Agni-vesha):
Agnivesha was an ancient Ayurvedic physician and author of the 'Agnivesha Samhita,' a classic text in Ayurveda. His contributions to Ayurvedic medicine, particularly in healing and treatment methodologies, are foundational, influencing subsequent texts and practices in traditional healthcare.
12) Disease:
Disease refers to any abnormal condition affecting the body, leading to impairment in normal functioning. In Ayurveda, diseases are understood as imbalances of doshas, dhatus, or mala. Treatment focuses on restoring harmony and addressing the root causes of the illness.
13) Shukla (Sukla):
Shukla refers to the author Shukla, who edited significant Ayurvedic texts. His work is important for preserving and propagating ancient wisdom, making it accessible for contemporary practitioners and scholars, thereby preserving the integrity of Ayurvedic practices.
14) Sira (Shira):
Sira indicates veins in Ayurveda, crucial for blood circulation. Understanding Sira is essential in diagnosing and treating conditions like DVT. Ayurvedic treatments often focus on the health and purity of the Sira to restore normal blood flow and overall health.
15) Pain:
Pain is a physical sensation signaling discomfort or distress, seen as an important symptom in various diseases. In Ayurvedic practice, it is viewed as a manifestation of dosha imbalance, necessitating treatments that restore harmony and alleviate suffering.
16) Vitiation (Vitiated):
Vitiation refers to the disruption or imbalance of doshas, dhatus, or mala, leading to disease. It is a core concept in Ayurveda that emphasizes the importance of maintaining balance within the body to prevent and treat illnesses effectively.
17) Medicine:
Medicine encompasses the science and practice of diagnosing, treating, and preventing diseases. Ayurvedic medicine, in particular, focuses on holistic approaches, incorporating natural remedies, dietary adjustments, and lifestyle changes to promote health and well-being.
18) Sharman (Sarma, Sarman, Sharma):
Sharma may refer to an author, researcher, or practitioner in the field of Ayurveda. Contributions from individuals with this surname often enhance the understanding of Ayurvedic principles, treatment practices, and their application in modern health scenarios.
19) Study (Studying):
Study refers to the systematic investigation of a subject to establish facts or reach new conclusions. In the medical context, studies involve clinical research evaluating treatment methods, patient outcomes, and the efficacy of traditional practices like Ayurveda for specific health conditions.
20) Ashtangahridaya (Astangahrdaya, Ashtanga-hridaya):
Ashtanga-hridaya is a prominent Ayurvedic text authored by Vagbhata. It summarizes various Ayurvedic principles and treatment modalities, serving as a foundational reference for practitioners. Its teachings integrate philosophy, clinical practices, and the Ayurvedic approach to health and disease management.
21) Ashtanga (Astanga, Ashtan-anga):
Ashtanga refers to the eight branches of Ayurveda, which encompass various aspects of health, including internal medicine, surgery, pediatrics, and more. This classification illustrates the depth and breadth of Ayurvedic practice, offering a holistic view of health and treatment.
22) Hridaya (Hrdaya):
Hridaya translates to 'heart' in Sanskrit and is used in the context of Ayurvedic texts. It signifies the core of Ayurvedic teachings, emphasizing the interconnection of mind, body, and spirit in achieving health and well-being, thus underpinning the holistic approach of Ayurveda.
23) Marathi:
Marathi is the language predominantly spoken in the Indian state of Maharashtra. Many important Ayurvedic texts have been translated into Marathi, making traditional medical knowledge accessible to a wider audience, aiding in the education and practice of Ayurveda in the region.
24) Delhi:
Delhi, the capital city of India, hosts various Ayurvedic educational institutions and healthcare facilities. Its role in integrating traditional practices into modern medicine is significant, supporting Ayurvedic studies, research, and patient care on a national level.
25) Kalpasthana (Kalpa-sthana):
Kalpasthana is one of the sections in classic Ayurvedic texts that deals with various treatment methodologies, especially concerning pharmacology and the preparation of medicines. It serves as a practical guide for practitioners to understand formulations and their applications.
26) Sutrasthana (Sutra-sthana):
Sutrasthana is another section within foundational Ayurvedic texts focusing on theoretical principles and basic concepts of Ayurveda. It lays the groundwork for understanding treatment approaches, physiological processes, and the philosophical underpinnings of Ayurvedic practice.
27) Sambandha (Sambamdha):
Sambandha in Ayurveda refers to the relationship or connection between different doshas, dhatus, and bodily functions. Understanding these relationships is crucial for diagnosing and treating diseases, allowing practitioners to tailor interventions according to an individual's unique constitution.
28) Ayurveda (Ayus-veda):
Ayurveda is an ancient Indian system of medicine emphasizing balance in the body, mind, and spirit. It incorporates various healing practices, including herbal remedies, dietary recommendations, and lifestyle modifications, to promote health and prevent illness, making it a holistic healthcare approach.
29) Spashta (Spasta):
Spashta means clear or distinct in Sanskrit. In the context of Ayurvedic diagnosis, it refers to the clarity or presence of symptoms, which aids practitioners in making informed decisions regarding treatment strategies and understanding a patient's condition in depth.
30) Pradhan:
Pradhan refers to the primary or principal force in a condition or treatment in Ayurveda. It denotes the most significant dosha or factor responsible for a health issue, guiding practitioners in selecting appropriate therapies to restore balance and promote healing.
31) Kutaki:
Kutaki, also known as Picrorhiza kurroa, is an important herb in Ayurveda used for detoxification and digestion. Its properties make it valuable in treatments aimed at balancing doshas, especially during therapies focused on purging toxins from the body.
32) Vyadhin (Vyadhi):
Vyadhi translates to disease in Ayurveda, encompassing various health conditions resulting from imbalances in the body. Understanding Vyadhi is essential for Ayurvedic practitioners to identify underlying causes and tailor treatment plans for effective healing and recovery.
33) Indian:
Indian refers to anything originating from the country of India, which has a rich cultural heritage encompassing traditional practices like Ayurveda. The Indian context is vital for understanding the historical and cultural framework within which Ayurvedic medicine evolved and is practiced today.
34) Kapha:
Kapha is the third dosha in Ayurveda associated with the elements of water and earth. It is responsible for stability, structure, and fluid balance in the body. Imbalances in Kapha can lead to conditions related to congestion and lethargy, requiring regulation for optimal health.
35) Cita:
Sidha translates to perfected or accomplished in Ayurveda, often referring to refined herbal preparations or medicines. It indicates the advanced stage of treatment or remedy that has undergone rigorous testing and validation for therapeutic efficacy.
36) Pune:
Pune is a city in India known for its educational institutions, including those specializing in Ayurveda. It serves as a hub for traditional medicine practices, research, and the dissemination of Ayurvedic knowledge, contributing to the enrichment of healthcare in the region.
37) Male:
Male refers to the biological sex of the individuals discussed in medical studies. Understanding gender differences is crucial in medical treatment and research as responses to therapies may vary between males and females, impacting clinical outcomes.
38) Mahamanjishthadi (Mahamanjisthadi, Maha-manjishthadi):
Mahamanjishthadi is a specific Ayurvedic formulation known for its blood-purifying properties. It is commonly used in treatments addressing blood disorders, enhancing circulation and promoting overall health by balancing the doshas involved in blood-related issues.
39) Tuberculosis:
Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, primarily affecting the lungs. Its management may involve a combination of traditional and modern medical approaches. Understanding its impact on overall health is essential in creating effective treatment strategies.
40) Pittarakta (Pitta-rakta):
Pitta-rakta refers to the interconnectedness of the Pitta dosha and Rakta dhatu in Ayurveda. This relationship is crucial for understanding various medical conditions, especially those involving inflammation and blood-related disorders, guiding effective treatment modalities.
41) Observation:
Observation in medical practice refers to the detailed examination and recording of a patient's symptoms, responses to treatment, and overall condition. It is a critical component of clinical assessments that informs diagnosis and subsequent therapeutic decisions.
42) Discussion:
Discussion in a medical context involves the analysis and interpretation of data, clinical findings, and treatment outcomes. It is an essential part of research articles, facilitating the exchange of ideas and insights among practitioners to improve understanding and practice.
43) Suffering:
Suffering denotes the experience of pain, distress, or hardship, often indicating underlying health issues. In Ayurveda, understanding the root causes of suffering is essential for devising treatment strategies aimed at alleviating discomfort and restoring well-being.
44) Upadhatu:
Upadhatu refers to the secondary or auxiliary tissues or substances in Ayurveda that support primary dhatus. These relationships are essential for understanding bodily functions and guiding treatments targeted at restoring balance among various bodily systems.
45) Nirgundi (Nirgumdi):
Nirgundi, also known as Vitex negundo, is an herb utilized in Ayurvedic medicine for its anti-inflammatory and analgesic properties. It is commonly used to alleviate pain and is included in treatments addressing joint and muscular issues.
46) Samhita:
Samhita refers to a collection of texts or treatises in Ayurveda, compiling knowledge about medicinal plants, treatment modalities, and healthcare principles. These texts are foundational to traditional Ayurvedic practices and education, preserving ancient wisdom.
47) Jalauka:
Jalauka, referring to leeches, is an Ayurvedic treatment technique employed in detoxification therapies and local bloodletting. It is particularly used for addressing conditions related to excess blood or inflammation, effectively restoring balance and promoting healing.
48) Itching:
Itching is an uncomfortable sensation that provokes the desire to scratch, often associated with skin conditions or allergies. In Ayurveda, it can indicate imbalances in doshas that need to be addressed through appropriate treatments to soothe and restore skin health.
49) Science (Scientific):
Science represents a systematic study of the physical and natural world, involving observation and experimentation. In the context of medicinal practices, it pertains to the evidence-based approach used to understand health conditions, inform treatments, and verify traditional healing techniques like Ayurveda.
50) Shabda (Sabda):
Shabda means sound or word in Sanskrit, referencing the importance of communication in conveying Ayurvedic knowledge. In healing practices, the right sound or mantra can significantly impact mental and physical well-being, illustrating the interconnection between sound and health.
51) Cancer:
Cancer is a group of diseases characterized by the uncontrolled growth of abnormal cells in the body. Its management requires a comprehensive approach, often combining modern medical treatments with traditional methods to enhance overall health and support recovery.
52) Edema (Oedema):
Oedema refers to the accumulation of excess fluid in the body's tissues, leading to swelling. In Ayurveda, it can be viewed as a sign of dosha imbalance, requiring interventions aimed at restoring fluid balance and addressing underlying causes.
53) Khanda (Khamda):
Khanda refers to a section or chapter within Ayurvedic texts that focuses on specific topics or treatments. Understanding the content within these sections aids practitioners in accessing vital information related to various health conditions and therapeutic strategies.
54) Dosha (Dosa):
Dosha refers to the three fundamental biological energies in Ayurveda: Vata, Pitta, and Kapha. Each dosha represents specific physiological functions and qualities in the body. Balancing these doshas is essential for optimal health, guiding treatment decisions in Ayurvedic practice.
55) Karma (Karman):
Karma in Ayurveda represents the concept of action and its consequences on health. It emphasizes the impact of lifestyle choices and decisions on wellness, highlighting the importance of aligning actions with the principles of health and well-being to foster positive outcomes.
56) Mutra:
Mutra means urine in Sanskrit and is considered an important excretory product in Ayurveda. The examination of mutra provides valuable insights into an individual's health status, helping practitioners understand dosha imbalances and guide treatment strategies accordingly.
57) India:
India is the country where Ayurveda originated, encompassing a rich heritage of traditional medicine practices. Understanding the cultural context of Indian Ayurveda is essential for appreciating its historical significance and ongoing relevance in modern healthcare.
58) Ulcer:
An ulcer is a sore on the skin or mucous membrane, often resulting from inflammation or infection. In Ayurveda, ulcers are addressed by understanding the underlying dosha imbalances and using appropriate herbs and treatments to promote healing.
59) Pulse:
Pulse is a vital sign reflecting the heart rate and rhythm, indicating overall cardiovascular health. In Ayurvedic diagnosis, pulse examination (Nadi Pariksha) helps assess dosha imbalances, informing treatment decisions based on physiological conditions.
60) Vega:
Vega denotes the urge or instinct in Ayurveda, particularly relating to bodily functions and actions. Recognizing the Vega is crucial for understanding natural physiological processes and ensuring timely interventions that align with the body's needs.
61) Guda:
Guda refers to the rectum or abode in Ayurveda, implicated in digestive and excretory health. Understanding the health of Guda is essential for diagnosing gastrointestinal disorders and tailoring treatments that promote digestive balance and overall well-being.
62) Medas (Meda, Medash):
Meda refers to fat or adipose tissue in the Ayurvedic context. It is essential for energy storage and sustaining health. Imbalances in Meda can lead to various health issues, making it important to monitor and manage it effectively in treatment protocols.
63) Nadi (Nadin):
Nadi means a channel or vessel in Ayurveda, encompassing both physical and energetic pathways within the body. Nadi examination is crucial for understanding circulation and overall health, guiding practitioners in diagnosing and treating various conditions.
64) Mala:
Mala refers to waste products in Ayurveda, such as excreted toxins from body processes. Proper elimination of Mala is crucial for maintaining health, as accumulations can lead to disease states. Treatments often focus on detoxifying and promoting healthy elimination.
65) Sama (Shama):
Sama means balanced or normal in Sanskrit, often used to describe a state of health where doshas are in equilibrium. Achieving Sama is a primary goal in Ayurveda, guiding practitioners to craft treatments that restore balance and promote wellness.
66) Sign:
Sign refers to observable indicators of a condition in medical diagnosis. Recognizing signs is essential for determining the presence of a disease and guiding treatment decisions, emphasizing the importance of thorough clinical examination.
67) Wall:
Wall can refer to a barrier or demarcation within anatomical descriptions in Ayurveda, particularly concerning organ structures or tissue boundaries. Understanding these delimitations is crucial for diagnosing disorders and guiding anatomical therapeutics.
68) Hand:
Hand signifies a part of the body involved in numerous functions, including manipulation and sensation. In Ayurvedic assessments, the hand may also serve as a diagnostic tool through pulse examination, reflecting the individual's health status.
69) Drug:
Drug refers to any substance that causes a physiological effect on the body, used in treatment for various illnesses. In Ayurveda, drugs often derive from natural sources, aimed at restoring balance and health through holistic therapeutic approaches.
Other Science Concepts:
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