Pharmacognostical and pharmaceutical evaluation of yavadilepa
Journal name: World Journal of Pharmaceutical Research
Original article title: Pharmacognostical and pharmaceutical evaluation of yavadilepa
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Soniya Parmar, Darshna H. Pandya, Harisha C. R. and V. J. Shukla
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Pharmacognostical and pharmaceutical evaluation of yavadilepa
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr20178-9126
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Summary of article contents:
Introduction
The article by Soniya Parmar et al. evaluates the pharmacognostical and pharmaceutical standards of Yavadilepa, an Ayurvedic formulation. This formulation addresses skin conditions common during adolescence, particularly those referred to in Ayurveda as Mukhdushika or Yauvan Pidika, which are facial eruptions caused by imbalances in the doshas of kapha, vata, and rakta. The research aims to standardize the formulation through comprehensive evaluation, highlighting the importance of establishing quality control parameters in herbal medicines.
Pharmacognostical Evaluation of Yavadilepa
The pharmacognostical evaluation of Yavadilepa reveals various medicinal components derived from three primary ingredients: Yava (Hordeum vulgare), Lodhra (Symplocos racemosa), and Yashtimadhu (Glycyrrhiza glabra). Under microscopic examination, several diagnostic features such as epidermal cells, stone cells, and specific crystal forms were identified, ensuring the genuineness of the raw materials utilized in the formulation. The organoleptic properties, including taste, color, odor, and texture, were also systematically recorded to affirm the authenticity of the product.
Physico-Chemical Analysis
The physico-chemical analysis of Yavadilepa indicates its suitability for use as a standard Ayurvedic face pack. The study recorded specific parameters such as loss on drying (10.83% w/w), ash value (5.9% w/w), and the water- and alcohol-soluble extract percentages (13.2% and 7.84% respectively). The pH of the formulation was found to be 6.5, which is compatible with skin use. These quantitative analyses contribute significantly to determining the quality and effectiveness of the formulation, giving insight into its stability and efficacy.
High-Performance Thin Layer Chromatography (HPTLC) Profile
The HPTLC analysis conducted for the Yavadilepa formulation revealed a distinctive fingerprint essential for its identification and quality control. Analysis under both short (254 nm) and long (366 nm) ultraviolet light showed seven prominent spots at each wavelength. Such chromatographic profiling is vital for ensuring consistency in composition and serves as a basis for further efficacy studies and standardization of Ayurvedic preparations, thus augmenting the credibility of herbal medicines in therapeutic applications.
Conclusion
The comprehensive pharmacognostical and pharmaceutical evaluation of Yavadilepa confirms its significance as a quality-controlled herbal formulation for treating adolescent skin conditions. The study provides a foundational reference for future research concerning the effectiveness and safety of this traditional medicine. The established parameters and findings highlight the necessity for rigorous quality assessment methods in Ayurveda, ensuring the reliability of herbal therapeutics in modern health practices.
FAQ section (important questions/answers):
What is the main focus of the study on Yavadilepa?
The study focuses on the pharmacognostical and pharmaceutical evaluation of Yavadilepa, a face pack made from natural ingredients, to establish quality control parameters as per Ayurvedic standards.
Which plants are used in the formulation of Yavadilepa?
Yavadilepa consists of three main components: Yava (Hordeum vulgare), Lodhra (Symplocos racemosa), and Yashtimadhu (Glycyrrhiza glabra), which are traditionally recommended for skin conditions.
What methodology was used for preparing Yavadilepa?
The preparation method involved procuring raw materials, authentication, and grinding the components in equal parts to create a fine powder before use in the formulation.
What physico-chemical parameters were analyzed in the study?
Parameters analyzed include loss on drying, ash value, water and alcohol soluble extracts, and pH, establishing quality benchmarks for Yavadilepa.
What were the findings of the HPTLC analysis of Yavadilepa?
The HPTLC analysis revealed 7 distinct spots at both 254 nm and 366 nm, indicating the presence of several active compounds with varying retention factors.
What is the significance of the study's conclusion?
The study concludes that the pharmacognostical and physicochemical evaluations confirm the genuineness of Yavadilepa's ingredients, providing a reference for future quality control research.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Pharmacognostical and pharmaceutical evaluation of yavadilepa”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Yashtimadhu (Yastimadhu, Yashti-madhu):
Yashtimadhu, known scientifically as Glycyrrhiza glabra, is a medicinal herb used in Ayurveda for its various health benefits. It is renowned for its soothing properties and is often included in formulations aimed at skin health. In the context of Yavadilepa, Yashtimadhu plays a crucial role by providing anti-inflammatory and healing effects, making it significant for addressing skin issues such as Yauvan Pidika.
2) Lodhra:
Lodhra, or Symplocos racemosa, is an important herb in Ayurveda recognized for its astringent properties. It is classified as one of the key ingredients in Yavadilepa, contributing to skin health and helping manage conditions like acne. Its efficacy in promoting skin clarity and combating blemishes stems from its traditional use in various Ayurvedic treatments.
3) Study (Studying):
The 'Study' refers to the comprehensive research conducted to evaluate the pharmacognostical and pharmaceutical properties of Yavadilepa. This research encompasses various analyses, including organoleptic and physicochemical evaluations that establish quality control parameters, aiming to validate the traditional uses of the formulation in treating skin diseases.
4) Pharmacognostical:
The term 'Pharmacognostical' involves the study of the physical, chemical, biochemical, and biological properties of drugs derived from natural sources. In this context, pharmacognostical evaluation of Yavadilepa is essential to authenticate its components, ensuring that the raw materials meet the required standards for efficacy and safety in Ayurvedic practices.
5) Soniya:
Soniya Parmar is the lead researcher and PG scholar involved in the study of Yavadilepa. Her contributions reflect credibility and expertise in the field of Ayurvedic pharmacology. Soniya's work aims to bridge traditional herbal medicines with modern scientific research, thereby enhancing the understanding and validation of these age-old practices.
6) Drug:
'Drug' in this context refers to a substance used for medical treatment. With respect to Yavadilepa, it elucidates how the combined herbs, specifically Yashtimadhu, Lodhra, and Yava, act synergistically to provide therapeutic effects aimed at treating skin conditions, showcasing the essence of herbal medicine.
7) Yava:
Yava, scientifically known as Hordeum vulgare (barley), is included in Yavadilepa for its beneficial properties in skin care. It is valued in Ayurveda for its cooling and soothing effects, helping to balance skin-related conditions. Yava's nutritional components also contribute to its efficacy as a natural remedy for skin issues.
8) Table:
'Table' here refers to the organized presentation of data and results within the study. It illustrates various parameters such as organoleptic characteristics, physicochemical properties, and analytical findings relevant to Yavadilepa. Structured tables facilitate easy comparison, understanding, and validation of the research findings, aiding in quality assessment.
9) Quality:
'Quality' pertains to the standards and characteristics that the formulation of Yavadilepa must meet to be deemed effective and safe. The study emphasizes quality control parameters such as physicochemical properties, thereby ensuring that the herbal formulation fulfills the necessary criteria for medicinal use as per Ayurveda.
10) Water:
In the context of the study, 'Water' signifies the solvent used for extracting pharmacologically active compounds from the herbs in Yavadilepa. The amount of water-soluble extract is a key parameter in evaluating the formulation's effectiveness, highlighting its relevance in assessing the therapeutic potential of the ingredients.
11) Ayurveda (Ayus-veda):
Ayurveda is an ancient Indian system of medicine focused on holistic health and natural remedies. The study of Yavadilepa is grounded in Ayurvedic principles, aiming to treat skin conditions through herbal formulations. This traditional approach underscores Ayurveda's relevance in contemporary herbal medicine and research methodologies.
12) Vikriti (Vikrti):
'Vikriti' refers to the bodily changes or imbalances that lead to disease, according to Ayurveda. The study discusses how Yavadilepa can help correct these imbalances, particularly in conditions like Yauvan Pidika, thereby emphasizing the importance of restoring harmony within the body's doshas to promote good health.
13) Pidika:
'Pidika' describes skin eruptions or lesions, particularly those occurring during adolescence. The term is directly linked to the conditions targeted by the Yavadilepa formulation. The study investigates Yavadilepa's efficacy in managing these skin issues through specific herbal combinations, making it significant within Ayurvedic dermatology.
14) Powder:
'Powder' refers to the physical form of the herbal components in Yavadilepa, which are ground into a fine texture for topical application. The powdered formulation is essential for ensuring even distribution on the skin, maximizing the absorption of active ingredients during treatment of skin conditions.
15) Glycyrrhiza glabra:
Glycyrrhiza glabra, commonly known as Yashtimadhu, is a key ingredient in Ayurveda recognized for its medicinal properties. It is often used for soothing skin irritations and promoting health. The study emphasizes its inclusion in Yavadilepa, reflecting its efficacy in treating skin disorders prevalent among adolescents.
16) Symplocos racemosa:
Symplocos racemosa, referred to as Lodhra, is a significant herb in Ayurvedic treatments, particularly for skin ailments. Its inclusion in Yavadilepa contributes to the formulation’s effectiveness, especially in addressing issues like acne and skin blemishes. The study highlights its role in the synergistic effect of herbal combinations.
17) Gujarat:
Gujarat is a state in India where the research on Yavadilepa was conducted. The region's rich tradition of Ayurveda and access to a variety of medicinal plants significantly contribute to the authenticity and relevance of the study, facilitating better understanding of local herbal practices and formulations.
18) India:
India is the birthplace of Ayurveda, a system of medicine that relies on natural herbs and holistic approaches. The study of Yavadilepa highlights traditional medicinal practices within India, contributing to the global understanding of herbal medicine and enhancing awareness of Ayurvedic formulations for modern therapeutic applications.
19) Hordeum vulgare:
Hordeum vulgare, commonly known as Yava (barley), is an integral component of Yavadilepa. Renowned for its health benefits, it contributes to the formulation's efficacy in treating skin issues. The study emphasizes its role in Ayurveda, showcasing how traditional knowledge utilizes such grains for therapeutic purposes.
20) Performance:
'Performance' in this study pertains to the effectiveness of Yavadilepa as a therapeutic agent in treating skin conditions. It evaluates how well the formulation meets medicinal claims based on scientific investigations into its pharmacognostic and physicochemical properties, thus validating its traditional use in Ayurveda.
21) Discussion:
'Discussion' refers to the section of the study where the findings related to Yavadilepa are interpreted and contextualized. It addresses the implications of the results, comparing them with existing literature, highlighting the significance, and suggesting future research directions within Ayurvedic pharmacognosy.
22) Inference:
'Inference' entails the conclusions drawn from the study regarding the efficacy and validity of Yavadilepa. It highlights the formulation's compliance with quality standards and its potential use in further research for quality control in herbal medicine, underpinning the importance of scientific validation in traditional practices.
23) Vitiation (Vitiated):
'Vitiation' refers to the imbalance of doshas that cause various health issues in Ayurveda. The study relates this concept to skin diseases like Yauvan Pidika, emphasizing how Yavadilepa aids in correcting these imbalances, thereby promoting skin health through its herbal components.
24) Shalmali (Salmali):
'Shalmali' refers to the silk cotton tree, which is considered significant in Ayurveda. While not directly mentioned in the primary formulation of Yavadilepa, its importance in traditional Ayurvedic texts may reflect the historical context of herbal treatments related to skin diseases addressed by Yavadilepa.
25) Medicine:
'Medicine' encompasses various substances used for treatment and healing. The study on Yavadilepa demonstrates how traditional herbal ingredients can serve as effective medicinal formulations under Ayurveda, validating the ongoing relevance of plant-based medicines in both historical and contemporary healing practices.
26) Harisha (Harisa):
Harisha C. R. is one of the authors involved in the research on Yavadilepa. His expertise and collaboration are crucial in the formulation of findings that contribute to the understanding of Ayurveda and the scientific evaluation of traditional herbal medicine, fostering further advancements in the field.
27) Disease:
In this context, 'Disease' signifies health conditions targeted by Yavadilepa, specifically skin disorders prevalent during adolescence. The study aims to explore the effects of the formulation in treating these diseases, emphasizing the holistic approach of Ayurveda in addressing not just symptoms but the root causes of health issues.
28) Shukla (Sukla):
V. J. Shukla is a key author in the study of Yavadilepa. His contributions support the legitimacy and scientific rigor of the research, playing a pivotal role in enhancing the understanding of Ayurvedic practices through meticulous analysis and validation of traditional remedies for skin health.
29) Indian:
'Indian' reflects the cultural and historical context of Ayurveda as an ancient medical system originating from India. The study connects Indian traditional practices with contemporary research methodologies, reinforcing the significance of native knowledge in shaping current understandings of herbal medicine and natural therapies.
30) Pandya (Pamdya, Pandyan):
Darshna H. Pandya is an author contributing to the study, adding valuable knowledge and expertise in the field of Ayurvedic pharmacology. Her involvement emphasizes the collaborative efforts in research aimed at enhancing the scientific basis of traditional herbal remedies and fostering their acceptance in modern medicine.
31) Kapha:
'Kapha' is one of the three doshas in Ayurveda, representing the elements of earth and water. The vitiation of Kapha can lead to various skin conditions. The study discusses how Yavadilepa can help in balancing Kapha, emphasizing its role in maintaining skin health and overall well-being.
32) Rakta:
'Rakta' is another dosha in Ayurveda, associated with blood and vitality. Its imbalance can contribute to various health issues, including skin disorders. The research highlights the importance of understanding Rakta's role in ailments like Yauvan Pidika, underlining how Yavadilepa helps restore balance among doshas for better skin health.
33) Vata:
'Vata' is the third dosha in Ayurveda, representing air and space. The study indicates that vitiation in Vata can lead to skin issues, among other health problems. Yavadilepa aims to harmonize Vata, illustrating the holistic approach of Ayurveda in effectively treating skin conditions by restoring dosha balance.
34) Pir:
'Peer' pertains to the social pressures and acceptance that often affect adolescents, influencing their self-image and mental health. The study emphasizes the psychological aspects of skin conditions like Yauvan Pidika, showing how traditional treatments like Yavadilepa can play a role in not just physical but also emotional healing.
35) Life:
'Life' signifies the overall well-being and health of individuals, particularly during crucial developmental years like adolescence. The study on Yavadilepa underscores the importance of natural remedies in promoting healthy skin, thus contributing positively to adolescents' self-image and overall quality of life, as emphasized in Ayurveda.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Pharmacognostical and pharmaceutical evaluation of yavadilepa’. Further sources in the context of Science might help you critically compare this page with similair documents:
Analytical study, Loss on drying, Ash value, Ayurvedic Pharmacopeia, Physico-chemical analysis, Pharmacognostical evaluation, Pharmaceutical evaluation, High performance thin layer chromatography (HPTLC), Water soluble extract, Alcohol-soluble extract, PH measurement, Organoleptic study, Epidermal cells, Mukhdushika, Chemical constituent, Quality control parameter.