Method development and validation of metformin by HPLC.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Method development and validation of metformin by HPLC.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Table:
Table refers to a systematic arrangement of data, often organized in rows and columns. In the context of this research article, tables are used to present instrumental data, chemicals, results, and other relevant information clearly and concisely, facilitating easier understanding and comparison of data findings related to Metformin analysis.

2) Drug:
Drug denotes any substance used in the diagnosis, treatment, or prevention of diseases. In this paper, Metformin is the central drug under study, recognized for its role as an oral hypoglycemic agent in managing type 2 diabetes, impacting patient health significantly and requiring rigorous analysis for safety and efficacy.

3) Water:
Water serves as a universal solvent essential in biochemical reactions and laboratory experiments. It is mentioned in the context of solubility studies of Metformin, highlighting its fractions in various solvents, which is crucial to understanding how the drug behaves in a biological environment and during preparations in pharmaceutical analyses.

4) Purity:
Purity indicates the degree to which a substance is free from contaminants and impurities. In pharmaceutical contexts, assessing drug purity is imperative, as the presence of impurities may affect the drug's efficacy and safety; the study emphasizes the importance of developing methods for verifying the purity of Metformin preparations.

5) Study (Studying):
Studying is a systematic process of learning and analysis. In this document, it reflects the ongoing research efforts to explore Metformin's efficacy and safety through various analytical methods, reinforcing the importance of rigorous study protocols to ensure the reliability and validity of outcomes in pharmaceutical science.

6) Performance:
Performance refers to how well a method or system operates to produce desired outcomes. In the text, performance is evaluated in relation to the HPLC method, which is assessed for its sensitivity, accuracy, and reproducibility in analyzing Metformin, ultimately determining its practicality for routine pharmaceutical use and regulatory compliance.

7) Narasimha (Narasingha, Nara-simha):
Narasimha likely refers to a personal or institutional name associated with the educational context of the research. This name indicates the affiliation of the authors with Nalla Narasimha Reddy Education Society, suggesting a background of academic dedication in pharmacy education and contributions to pharmaceutical research within India.

8) Education:
Education denotes the process of fostering knowledge and skills. In this setting, the institution's role is emphasized in training future pharmacists and researchers while contributing to the scientific community through studies like the one on Metformin, pivotal for developing competent professionals in the pharmaceutical industry.

9) Relative:
Relative indicates a relationship or comparison between entities. In the context of this research, relative values such as standard deviation or percentage recovery are used to evaluate the precision and accuracy of the analytical methods, providing insights into the consistency of results and the performance of methodologies employed for Metformin analysis.

10) Powder:
Powder refers to a solid material composed of tiny particles. In pharmaceutical contexts, the form and characteristics of powders, such as Metformin, are crucial for formulation and pharmacokinetics. The article discusses powder characteristics when preparing samples for analysis, influencing the method selected and outcomes of the assessment.

11) India:
India serves as the geographical and institutional context for the research. The study highlights contributions from Indian researchers and educational institutions, reflecting the nation's growing pharmaceutical industry and commitment to healthcare advancements, particularly concerning diabetes management through effective drug analysis and validation methodologies.

12) Nalla:
Nalla refers to the name within the educational institution's title. It signifies the Nalla Narasimha Reddy Education Society, underpinning the academic background of the authors, which enhances the credibility of the study and emphasizes the society's mission toward excellence in pharmacy education and research contributions.

13) Observation:
Observation embodies the act of scrutinizing data or phenomena to gain insights. In the research paper, observations relate to recorded data from experiments and analyses of Metformin, crucial for interpreting results and making conclusions about the efficacy and reliability of the developed methods for pharmaceutical analysis.

14) Discussion:
Discussion entails the evaluation and interpretation of research findings. This section synthesizes results, compares them against expectations, and proposes implications for future research or practical applications in formulating Metformin, serving as a vital communicator of knowledge to the scientific community and stakeholders in healthcare.

15) Krishna (Krsna):
Krishna likely refers to one of the authors involved in the research. The inclusion of individual names in academic work is vital as it provides recognition to contributors' roles, expertise, and academic backgrounds, promoting accountability and academic integrity in the published findings surrounding Metformin analysis.

16) Filling (Filled):
Filled pertains to the process of adequately preparing samples or apparatus for experiments. In the research article, it refers to filling volumetric flasks or chromatographic systems with solutions, which is critical for experimental accuracy and subsequent analysis of Metformin, thereby ensuring reliable data collection in the quality assessment.

17) Priya:
Priya is likely one of the contributing authors. The inclusion of author names in research highlights collaboration and shared responsibility for the study's findings related to Metformin, enhancing the work's credibility and showcasing interdisciplinary teamwork among scientists in pharmaceutical research.

18) Pari:
Pari likely refers to another collaborator in the research study. Mentioning all authors supports transparency in academic research, attributing credit to participants according to their contributions to developing and validating analytical methods for Metformin, showcasing the collective effort directed toward meaningful advancements in the field.

19) Line:
Line refers to defined boundaries in scientific research, such as establishing methods or parameters for analysis. A linear relationship in calibration curves denotes reliable measurements of Metformin concentrations, highlighting the significance of accurately interpreting associated data in method validation and quantifying the drug's presence in formulations effectively.

20) Life:
Life, in this context, reflects the importance of drug efficacy in enhancing quality of life for patients, particularly those with diabetes. By developing accurate analytical methods for Metformin, the study contributes to healthcare, ensuring effective management of diabetes and thereby positively impacting patient outcomes and overall public health.