Effects of Unani herbs in obesity and related comorbidities.

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Journal name: World Journal of Pharmaceutical Research
Original article title: Potential effects of unani herbs in the management of obesity and its related comorbidities – a systematic review
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Original source:

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Author:

Sabiha Fatima, Mohd Shahid, Danish Mand, Shagufta Parveen and Iram Naaz


World Journal of Pharmaceutical Research:

(An ISO 9001:2015 Certified International Journal)

Full text available for: Potential effects of unani herbs in the management of obesity and its related comorbidities – a systematic review

Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research

Doi: 10.20959/wjpr201710-9472


Download the PDF file of the original publication


Summary of article contents:

Introduction

Obesity is increasingly recognized as a critical risk factor for various chronic diseases, with its prevalence escalating globally. It is characterized by an excess of adipose tissue, typically measured by a Body Mass Index (BMI) of 30 kg/m² or greater. Contributing factors to obesity are diverse, including genetics, lifestyle, metabolism, and environmental influences, with energy imbalance serving as the fundamental cause. Conventional medicine has yet to provide a reliable and effective treatment for obesity, prompting interest in alternative approaches, particularly those rooted in traditional medicine such as Unani medicine. This systematic review evaluates the effectiveness of Unani herbs in managing obesity and its associated comorbidities.

The Role of Unani Medicine in Obesity Management

In Unani medicine, obesity is referred to as Samne Mufrit and is classified as a phlegmatic disorder (Balghami), which is believed to arise from poor metabolic functioning and unhealthy dietary practices. The treatment principles focus on restoring balance through various natural regimens and medicinal herbs. Unani practitioners have identified several herbs and formulations that are believed to possess therapeutic properties effective in managing obesity. These treatments are based on the concept of Ilaj bil zid (heteropathy), where specific formulations are designed to counteract the underlying imbalances contributing to obesity, such as increased moisture (ratoobat) and reduced dryness (yaboosat).

Synergistic Effects of Unani Herbs

Unani medicine utilizes various herbs known for their anti-obesity effects. For instance, herbs like Ajmood (celery), Anisoon (aniseed), and Dhaniya (coriander) not only aid in weight management but also provide additional health benefits, including anti-inflammatory, diuretic, and hypoglycemic properties. Table 1 in the review details specific Unani herbs and their respective activities, showcasing the rich pharmacological potential of these traditional remedies. The synergistic action of these herbs not only assists in reducing body weight but also addresses associated risk factors, such as high blood pressure and cholesterol levels.

Mechanisms of Action in Anti-Obesity Treatment

The review further discusses the various mechanisms through which Unani herbs exert their anti-obesity effects. This includes reducing energy intake, enhancing energy expenditure, inhibiting adipocyte differentiation, and promoting fat oxidation. Several medicinal plants are noted for their ability to modulate metabolic processes, such as lipolysis and fat absorption, thus performing multifaceted roles in obesity management. Noteworthy is the potential role of antioxidants present in these herbs, which may also combat the oxidative stress often associated with obesity, thereby reducing the risk of related health complications.

Conclusion

The systematic review emphasizes the potential role of Unani medicine in the management of obesity as a safe and cost-effective alternative to conventional treatments. The identification and application of various herbs with defined anti-obesity activities reflect the depth of traditional knowledge that can complement modern therapeutic strategies. However, to fully harness the benefits of these herbal treatments, there is a crucial need for scientific validation, standardization, and safety assessments. More research is essential to reaffirm the efficacy of these traditional practices and integrate them into a holistic approach for tackling obesity and its associated health issues.

FAQ section (important questions/answers):

What is the main concern regarding obesity as per the research?

Obesity is seen as a major risk factor for chronic diseases, including diabetes, heart disease, and certain cancers, impacting overall health negatively.

What are common treatments for obesity in Unani medicine?

Unani medicine offers several treatments for obesity utilizing herbs and compound formulations aimed at balancing bodily humors and improving metabolism.

What factors contribute to obesity according to the article?

Factors include genetic predisposition, environmental influences, cultural norms, hormonal imbalances, and lifestyle choices leading to energy imbalance.

What benefits can modest weight loss provide?

Even a modest weight loss of 5-10% can significantly improve conditions such as diabetes, hypertension, and reduce risks associated with heart disease.

How do Unani herbs assist in weight management?

Unani herbs may aid in weight management by enhancing metabolism, reducing appetite, and improving energy expenditure through various biochemical mechanisms.

What is the conclusion about Unani herbs in obesity management?

Unani herbs are considered promising for obesity management, requiring further scientific validation for their effectiveness and safety before widespread adoption.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Effects of Unani herbs in obesity and related comorbidities.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Delhi:
Delhi is the capital territory of India, known for its historical significance and as a political hub. It is relevant in the context of traditional and modern medicine, where institutions such as AIIMS and various Unani medicinal practices contribute to healthcare research and treatment approaches.

2) Medicine:
Medicine encompasses the science and practice of diagnosing, treating, and preventing diseases. It includes various systems like conventional and traditional medicine, such as Unani, which offers natural remedies and therapies for conditions like obesity, emphasizing the importance of holistic health.

3) New Delhi:
New Delhi, as the capital of India, is a significant location for medical research, education, and healthcare policy. It's home to renowned medical institutes and practitioners who explore both modern and traditional medicinal approaches, particularly in fields like Unani medicine.

4) Drug:
A drug is a substance used for medical treatment to prevent or cure diseases. In the context of obesity management, both synthetic and herbal drugs (like those in Unani medicine) are explored to help reduce body weight and treat its related comorbidities.

5) Disease:
Disease refers to any abnormal condition affecting the body, often associated with specific signs and symptoms. The review discusses obesity as a disease, highlighting its impact on health, including comorbidities like diabetes, heart disease, and the role of Unani herbs in its management.

6) Science (Scientific):
Scientific refers to methods based on systematic study and experimentation. The review stresses the need for a scientific validation of Unani remedies for obesity to support their integration into modern healthcare practices.

7) India:
India is a diverse country with a rich history of traditional medicine systems, including Unani. The prevalence of obesity and related health issues in India highlights the need for effective treatment modalities, where natural remedies play a crucial role in healthcare.

8) Table:
Tables in the document illustrate various Unani herbs and their properties, indicating their relevance in treating obesity. These structured displays provide a clear overview of the botanical names, common names, and therapeutic activities of different herbs.

9) Indian:
Indian refers to anything related to India, including its cultures, traditions, and medicinal practices. The review emphasizes Indian herbal medicines in the context of obesity management, showcasing the importance of traditional remedies derived from indigenous flora.

10) Blood:
Blood is a crucial body fluid involved in the transportation of nutrients, oxygen, and waste products. The review discusses how obesity influences blood parameters and the potential of Unani herbs to improve blood lipid levels and overall health.

11) Activity:
Activity generally refers to a state of being active or performance of actions. In the context of the review, it relates to the physiological effects of Unani herbs, such as their ability to promote weight loss and improve metabolic functions.

12) Desi (Deshi):
Desi refers to indigenous or native practices and cultural elements of the Indian subcontinent. In this context, it highlights the use of local Unani herbs and treatments that are traditional yet relevant in addressing modern health challenges.

13) Food:
Food plays a vital role in obesity management, as dietary habits significantly influence caloric intake. The review addresses the importance of dietary modifications and supplements, including Unani herbs, as parts of a holistic approach to weight management.

14) Anana:
Anana (pineapple) is a fruit highlighted for its potential health benefits. In herbal traditions, it is valued for its anti-inflammatory and digestive properties, contributing to overall health and possibly assisting in obesity management.

15) Water:
Water is essential for all bodily functions and influences metabolism. The review suggests maintaining hydration as part of a weight management strategy, and the involvement of water-based infusions or decoctions in traditional remedies is discussed.

16) Masha (Masa, Ma-sha):
Masha refers to a unit of measurement traditionally used in Unani medicine for herbal dosages. Understanding these measurements is crucial for proper administration of herbal formulations in managing conditions like obesity.

17) Tola:
Tola is also a unit of weight used in traditional medicine, especially in the context of Unani practices. Proper dosage measurements are critical to ensuring effective treatment and adherence in herbal medicine applications.

18) Bora:
Bora refers to Armenian bole, a natural clay used in traditional medicine practices, often for its health-promoting properties. In Unani texts, it may be included in formulations aimed at treating various disorders, including obesity.

19) Sah:
Shah (meaning king or ruler) may refer to significant figures or physician scholars in Unani medicine, whose teachings contributed to the development of herbal remedies for managing diseases like obesity and enhancing public health knowledge.

20) Tree:
Tree often symbolizes the source of many herbal remedies. In the review, various herbs derived from trees are explored for their therapeutic potential in obesity management, indicating the importance of natural products.

21) Nardostachys jatamansi (Nardostachys jatamamsi):
Nardostachys jatamansi, known as jatamansi, is highlighted for its medicinal properties in traditional systems. It is recognized for its potential anti-obesity effects, making it an important herb in the Unani pharmacopoeia for managing weight.

22) Zingiber officinale:
Zingiber officinale, commonly known as ginger, is a well-known herb with numerous health benefits. It is often used in both culinary and medicinal contexts to enhance metabolism and aid digestion, supporting weight management efforts.

23) Cyperus rotundus:
Cyperus rotundus, or nut grass, is highlighted for its therapeutic properties, including anti-obesity effects. Its inclusion in Unani formulations showcases the diversity of plants used in traditional medicine to combat obesity and related health issues.

24) Crocus sativus:
Crocus sativus, commonly known as saffron, is prized for its flavor and potential health benefits. It has been studied for its mood-enhancing and weight management properties, making it significant in both culinary and medicinal practices.

25) Curcuma longa:
Curcuma longa, or turmeric, is widely recognized for its anti-inflammatory and antioxidant properties. Its inclusion in obesity management through Unani medicine highlights its role in improving overall health and metabolic function.

26) Indian jujube:
Indian jujube (Ziziphus jujuba) is recognized in traditional medicine for its various health benefits, including its potential to aid digestion and enhance metabolic processes, relevant for obesity management.

27) Bitter gourd:
Bitter gourd, or Momordica charantia, is known for its anti-diabetic and weight-loss properties. It is often included in traditional diets and herbal treatments to manage obesity.

28) Nut grass:
Nut grass (Cyperus rotundus) is often used in herbal traditions for its medicinal properties. Its role in promoting health and potentially aiding in weight management is discussed in the text.

29) Cow milk (Cow's milk):
Cow milk serves as a staple in many diets and is often utilized in traditional medicine. Its nutritional components can support overall health, which is integral in managing obesity.

30) Momordica charantia:
Momordica charantia, commonly known as bitter gourd, has been studied for its anti-diabetic and weight-loss properties. It plays a significant role in traditional remedies aimed at obesity management.

31) Solanum melongena:
Solanum melongena, or eggplant, is recognized for its low-calorie content and high fiber content, making it beneficial for weight management. It is often included in diets aimed at reducing obesity.

32) Commiphora mukul:
Commiphora mukul, also known as myrrh, possesses various pharmacological properties, including anti-inflammatory effects. Its application in traditional remedies for weight control emphasizes its healing properties.

33) Pharmacological:
Pharmacological refers to the study of drugs and their effects on biological systems. This term is relevant in analyzing the potential impacts of Unani herbs on health, particularly in managing obesity and its comorbidities.

34) Allium sativum:
Allium sativum, or garlic, is recognized for its medicinal properties, including anti-inflammatory and cardiovascular benefits. It is frequently used in herbal remedies for weight management.

35) Accumulation (Accumulating, Accumulate):
Accumulation refers to the increase of substances, such as fat in obesity. Understanding the mechanisms of accumulation helps inform treatment strategies, emphasizing the role of herbs in controlling weight gain.

36) Discussion:
Discussion here refers to the examination of relevant research findings on obesity treatment and management using Unani herbs. Engaging in discussions surrounding traditional practices highlights their potential in providing health solutions.

37) Meenakshi:
Meenakshi may refer to scholars or practitioners associated with Unani therapies. Their contributions to understanding herbal properties are essential for integrating traditional knowledge into modern medicine.

38) Fenugreek:
Fenugreek (Trigonella foenum-graecum) is known for its multiple health benefits, including aiding metabolism and weight management. It is frequently incorporated in traditional remedies for obesity control.

39) Knowledge:
Knowledge refers to the understanding gained through learning and experience. In this context, the review emphasizes the importance of recognizing and applying traditional medicinal knowledge in the management of obesity.

40) Jabalpur:
Jabalpur is a city in India recognized for its contributions to medical education and practice, including Unani medicine. The local practices and studies made in such regions are significant in addressing health issues like obesity.

41) Turmeric:
Turmeric (Curcuma longa) is extensively acknowledged for its anti-inflammatory and antioxidant properties. Its incorporation into diets and remedies for obesity helps promote better metabolic health.

42) Pavitra:
Pavitra can imply purity or sacredness in traditional practices. In the context of herbal medicine, it signifies the natural, unadulterated properties of herbs used for treating obesity.

43) Burning (Burn, Burned, Burnt):
Burning generally refers to the process of metabolizing fat for energy. Understanding the biological mechanisms behind fat burning is crucial in developing effective strategies for obesity management.

44) Cancer:
Cancer refers to a group of diseases characterized by uncontrolled cell growth. The review discusses the link between obesity and the increased risk of various cancers, indicating the importance of managing obesity to reduce such risks.

45) Garlic:
Garlic (Allium sativum) is lauded for its numerous health benefits, including anti-obesity effects. Its inclusion in Unani remedies helps address weight management and cardiovascular health.

46) Bitter:
Bitter may refer to the taste profile of certain medicinal foods and herbs like bitter gourd, which is beneficial for digestion and has properties that support weight loss.

47) Pigeon:
Pigeon often refers to traditional practices or symbols of peace. In herbal context, it might not have direct correlation, but could relate to cultural symbolism surrounding health and nature.

48) Cata:
Saadaa refers to simplicity or purity, often related to traditional lifestyles. In herbal medicine, this notion reinforces the use of natural, simple ingredients to achieve health benefits.

49) Cilli:
Chilli contributes to diet as a spice and has properties that can boost metabolism. Including it in traditional herbal treatments can aid in weight management.

50) Methi:
Methi, or fenugreek, is noted for its health benefits, including aiding weight loss and improving metabolic health. It is often prescribed in herbal treatments.

51) Kabir:
Kabir may refer to esteemed scholars or practitioners who have contributed to the field of Unani medicine. Their insights dramatically affect treatment practices for various diseases, including obesity.

52) Sahi:
Shahi implies royal or dignified. In the context of herbal medicine, it may refer to prestigious herbs or treatments revered for their effectiveness.

53) Hindi (Himdi):
Hindi is one of the major languages of India, representing a significant cultural and educational aspect. It connects traditional knowledge to the general populace, facilitating discussions on topics like Unani medicine.

54) Shada (Sada, Sadas):
Sada denotes simplicity or a straightforward approach. In herbal practices, it reinforces the utility of uncomplicated remedies for effective treatment without complications.

55) Dana:
Dana generally means seeds or grains and holds importance in traditional diets. Seeds like those from fenugreek are often used in herbal practices, contributing to health improvements.

56) Alam (Alaṁ):
Alam can denote knowledge or cultural heritage. In the context of traditional medicine, it emphasizes the importance of understanding historical practices for current health benefits.

57) Soya:
Soya, or soy, is noted for its nutritional benefits, including protein content. It plays a role in dietary management for obesity through promoting satiety and reducing fat intake.

58) Bile:
Bile plays a critical role in digestion and fat metabolism, influencing obesity management strategies. Understanding its function can enhance the effectiveness of dietary interventions.

59) Dang:
Dang may refer to traditional measurements or practices. In herbal medicine, precise measurements of ingredients are crucial for the successful formulation of medicinal products.

60) Diet:
Diet relates to the food consumed and has a direct impact on obesity management. The review discusses dietary adjustments alongside herbal treatments to promote health and weight loss.

61) Bird:
Bird may symbolize freedom or health in various cultures. In herbal medicine, the term is less directly relevant but can represent the natural, wild origins of certain herbs.

62) Milk:
Milk is a vital source of nutrition and plays a role in traditional diets. It is often combined with herbal treatments to enhance their effects and improve health outcomes.

63) Mud:
Mood influences eating behaviors and overall health. Managing mood through herbs may support weight loss efforts, making it a relevant factor in obesity management.

64) Cina:
Sina refers to Avicenna, a prominent figure in traditional medicine whose works guide herbal practices. His teachings provide foundational knowledge in applying herbs for various health concerns.

65) Pur:
Poor or inadequate means insufficient resources or knowledge. In the context of healthcare, this may highlight the need to improve access to effective treatments for obesity management, particularly in marginalized populations.

Other Science Concepts:

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Discover the significance of concepts within the article: ‘Effects of Unani herbs in obesity and related comorbidities.’. Further sources in the context of Science might help you critically compare this page with similair documents:

Chronic disease, Dietary regimen, Herbal medicine, Anti-inflammatory activity, Socioeconomic factors, Conventional medicine, Scientific validation, Obesity management, Weight loss, Energy imbalance, Unani herbs, Risk profile, Unani physicians, Evidence-based treatment, Compounding formulation.

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