Phytochemical, antioxidant, and antimicrobial studies of Santalum album bark.
Journal name: World Journal of Pharmaceutical Research
Original article title: Studies on phytochemical screening, antioxidant and antimicrobial studies of santalum album bark extract
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
This page presents a generated summary with additional references; See source (below) for actual content.
Original source:
This page is merely a summary which is automatically generated hence you should visit the source to read the original article which includes the author, publication date, notes and references.
Jayasimha Rayalu Daddam
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Studies on phytochemical screening, antioxidant and antimicrobial studies of santalum album bark extract
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr201714-10009
Copyright (license): WJPR: All rights reserved
Download the PDF file of the original publication
Summary of article contents:
Introduction
Research conducted on the bark extract of Santalum album has emphasized its potential medicinal benefits, particularly regarding its phytochemical properties and biological activities. The study highlights the importance of traditional medicinal plants and their adaptation in modern medicine. Phytochemical screening reveals various compounds that may contribute to antioxidant and antimicrobial activities, enhancing the reliability of Santalum album as a therapeutic agent in treating health disorders.
The Role of Adaptogens
The concept of adaptogens, defined as natural substances that help the body adapt to stressors, has gained prominence in both traditional and modern medicine. Adaptogens are believed to enhance the body’s resistance against physical, chemical, and biological stressors. Historical references in systems like Ayurveda articulate the use of various plants, including Santalum album, to bolster health without adverse effects. This concept has driven research into plant-derived compounds with stress-reducing properties, showcasing the critical relevance of adaptogens in developing treatments for stress-related conditions.
Phytochemical Composition and Antioxidant Activity
Phytochemical screening of Santalum album reveals a variety of secondary metabolites, including steroids, triterpenes, saponins, alkaloids, carbohydrates, flavonoids, tannins, and glycosides. Notably, ethanolic extracts exhibited the highest concentrations of these compounds, correlating with significant antioxidant activity, particularly against DPPH radicals. The results indicate that the extract’s capability to scavenge free radicals aligns with its phenolic and flavonoid content, underscoring the extract's potential as a natural source for antioxidant-rich therapeutic agents.
Antimicrobial Properties
The antimicrobial activities of Santalum album have been thoroughly investigated, demonstrating efficacy against key pathogenic microorganisms, including Staphylococcus aureus, Pseudomonas aeruginosa, and Aspergillus niger. Ethanolic extracts particularly displayed notable antimicrobial effectiveness, evidenced by measurable zones of inhibition. This antimicrobial potential is intricately linked to the phytoconstituents present in the extract, which vary depending on the solvent used during extraction. Such findings portray Santalum album as a promising candidate for developing natural antimicrobial agents.
Conclusion
Overall, the research on Santalum album bark extract compiles significant evidence regarding its phytochemical constituents and biological activities, highlighting its therapeutic potential in tackling health issues linked to oxidative stress and microbial infections. As traditional medicinal practices integrate with modern scientific validation, Santalum album exemplifies the future of herbal medicine in providing effective, natural solutions for health management. Further exploration into its adaptogenic properties and applications in pharmacology may pave the way for innovative therapeutic approaches that harness the wisdom of natural remedies.
FAQ section (important questions/answers):
What was the focus of the study on Santalum album bark extract?
The study focused on the phytochemical screening, antioxidant properties, and antimicrobial activity of Santalum album bark extract, aiming to identify various compounds and their potential health benefits.
Which extract showed the highest antioxidant activity in Santalum album?
The ethanolic extract exhibited the highest antioxidant activity compared to other solvent extracts when evaluated using the DPPH scavenging method.
What antimicrobial properties were observed in Santalum album extracts?
Ethanolic extracts of Santalum album demonstrated significant antimicrobial activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Aspergillus niger, inhibiting their growth.
What phytochemicals were detected in Santalum album bark extract?
Phytochemical screenings revealed the presence of steroids, triterpenes, saponins, alkaloids, carbohydrates, flavonoids, tannins, and glycosides in the ethanolic extracts of Santalum album.
How was the phytochemical extraction carried out for Santalum album?
The bark material was extracted using 50% ethanol, methanol, and distilled water through hot reflux extraction techniques over several hours for comprehensive analysis.
What traditional uses does Santalum album have in medicine?
Santalum album has been historically used in traditional medicine for its adaptogenic properties, enhancing resistance to stress and promoting overall health in Ayurvedic practices.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Phytochemical, antioxidant, and antimicrobial studies of Santalum album bark.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Activity:
Activity in the context of the study refers to the biological effects exhibited by the extracts of Santalum album, particularly its potential antioxidant and antimicrobial properties. Measuring activity is crucial for evaluating the medicinal efficacy of natural substances and their ability to combat diseases and promote health.
2) Santalum album:
Santalum album, commonly known as sandalwood, is a significant medicinal plant studied for its phytochemical compounds. Its bark possesses various bioactive components that contribute to antioxidant and antimicrobial activities, making it relevant in phytotherapy and traditional medicine, particularly in Ayurvedic practices.
3) Phytochemical:
Phytochemical refers to the bioactive compounds found in plants with health-promoting properties. In this study, phytochemical screening of Santalum album revealed the presence of various classes like flavonoids, saponins, and tannins, which contribute to its pharmacological effects including antioxidant and antimicrobial actions.
4) Medicine:
Medicine encompasses various practices aimed at treating and preventing diseases. This study emphasizes traditional medicine, particularly Ayurvedic practices that utilize plants like Santalum album to enhance health, showcasing the importance of integrating phytotherapy into modern medical paradigms.
5) Table:
Tables in scientific research are used to organize data systematically, facilitating comparison and analysis. In this study, tables summarize phytochemical screening results and antioxidant activities, enabling clearer interpretation of the findings related to Santalum album's medicinal potential.
6) Flavonoid:
Flavonoids are plant-derived compounds known for their antioxidant properties and potential health benefits. The study identified flavonoids in Santalum album's extracts which contribute to its ability to scavenge free radicals, showcasing the importance of these compounds in therapeutic applications.
7) Aureus:
Aureus refers to Staphylococcus aureus, a pathogenic bacterium studied for its role in various infections. The antimicrobial activity of Santalum album extracts was tested against this bacterium, highlighting its potential as a natural remedy for combating such pathogens.
8) Medium:
In microbiological contexts, medium refers to the nutrient-rich environment used to grow microorganisms. The study utilized specific media for culturing bacteria and fungi, ensuring optimal growth conditions for assessing the antimicrobial efficacy of Santalum album extracts.
9) India:
India is a country rich in biodiversity and traditional medicine systems like Ayurveda. The study emphasizes the importance of Indian medicinal plants such as Santalum album, which play a vital role in natural healing practices and potential drug development.
10) Water:
Water is a universal solvent crucial for extracting bioactive compounds from plant materials. In the study, aqueous extracts of Santalum album were analyzed for their phytochemical properties, illustrating the importance of different solvents in evaluating plant efficacy.
11) Drug:
A drug is a chemical substance used for medical treatment, which can include natural products from plants. Santalum album's extracts are being researched for their potential as natural drugs to treat various ailments, highlighting the bridge between traditional and modern pharmaceuticals.
12) Withania somnifera:
Withania somnifera, also known as Ashwagandha, is an adaptogenic herb used in Ayurvedic medicine. The mention of this plant in the study underscores the growing interest in herbal remedies and their potential to enhance health and resilience against stress.
13) Pharmacological:
Pharmacological refers to the branch of medicine concerned with the uses, effects, and actions of drugs. The study explores the pharmacological activities of Santalum album, linking its traditional uses to scientific investigations of its efficacy and therapeutic potential.
14) Substance:
In this study, substance generally refers to the chemical compounds extracted from Santalum album. These substances are analyzed for their biological activities, revealing how various plant-derived elements contribute to health-improving properties.
15) Rasayana (Rasa-ayana):
Rasayana is a concept in Ayurveda referring to rejuvenating therapies that promote vitality and longevity. This study aligns with the Rasayana tradition by investigating Santalum album's potential benefits as a restorative agent in modern medicine.
16) Study (Studying):
The study serves as a scientific investigation into the phytochemical and pharmacological properties of Santalum album. Such studies are critical for validating traditional medicinal practices and exploring novel therapeutic options derived from natural sources.
17) Pharmacology:
Pharmacology is the science of drugs, their actions, and how they affect biological systems. The relevance of pharmacology in this study lies in understanding how Santalum album extracts can be applied therapeutically to enhance health and treat diseases.
18) Disease:
Disease refers to any malfunctioning or maladaptation of biological systems in an organism. The study focuses on how Santalum album may provide therapeutic benefits against microbial diseases, showcasing its relevance in public health.
19) Indian:
Indian signifies the cultural and geographical context where Santalum album is utilized. The study highlights traditional Indian medicine and the valuable role of indigenous plants in maintaining health and treating ailments.
20) Ocimum sanctum:
Ocimum sanctum, commonly known as Holy Basil or Tulsi, is another herb with known health benefits. Its mention alongside Santalum album emphasizes the diversity of Indian medicinal plants that are studied for their adaptogenic and therapeutic properties.
21) Jayasimha:
Jayasimha Rayalu Daddam is the author of the study, whose work contributes to the understanding of Santalum album. Identifying the author highlights the significance of individual contributions to the collective body of knowledge in medicinal research.
22) Ayurveda (Ayus-veda):
Ayurveda is an ancient Indian system of medicine focusing on holistic health. The study contextualizes Santalum album within Ayurvedic traditions, emphasizing the integration of ancient wisdom with contemporary scientific research.
23) Samhita:
Samhita refers to ancient texts that compile knowledge on various subjects, including medicine. In this context, it relates to the foundational Ayurvedic texts that describe the therapeutic uses of plants like Santalum album.
24) Gelatin:
Gelatin is a substance derived from collagen, often used in laboratory settings. In this study, it is mentioned in relation to the testing methods for phytochemicals, illustrating the various reagents necessary for scientific analyses.
25) Garlic:
Garlic is noted for its medicinal properties and health benefits. Its mention serves to connect the study's findings with a broader context of natural remedies that are traditionally used for health improvement.
26) Botany:
Botany is the scientific study of plants and their properties. The study of Santalum album emphasizes the botanical aspects of medicinal plants, highlighting the significance of understanding plant taxonomy and phytochemistry in pharmacology.
27) Sugar:
Sugar in this context refers to carbohydrates present in the plant extracts. Their presence is assessed during phytochemical screenings, showcasing the diverse range of bioactive compounds contributing to the extract's overall medicinal value.
28) Tinospora cordifolia:
Tinospora cordifolia is another significant plant in Ayurvedic medicine known for its adaptogenic properties. Its citation alongside Santalum album reinforces the potential for synergistic effects and the importance of studying multiple herbs.
29) Phyllanthus emblica:
Phyllanthus emblica, or Amla, is an important fruit in Ayurveda known for its antioxidant properties. Its mention underscores the tradition of using various botanical sources to combat oxidative stress and promote health.
30) New Delhi:
New Delhi, the capital of India, is a hub for research and education. Its mention indicates the geographical context where numerous studies are being conducted, including those exploring traditional medicines like Santalum album.
31) Sutrasthana (Sutra-sthana):
Sutrasthana refers to a section within ancient Ayurvedic texts that discuss various aspects of medicine. Its inclusion signifies the scholarly foundation that informs contemporary research on traditional remedies like Santalum album.
32) Surrounding:
Surrounding refers to the environmental and contextual factors that influence health. The study aligns with cases where plants are viewed as part of a holistic approach to health, echoing traditional views of the interplay between nature and well-being.
33) Ashvagandha (Asvagandha, Ashwagandha, Ashvagamdha, Ashva-gandha):
Ashwagandha, or Withania somnifera, is another crucial adaptogen known for its stress-reducing properties. Mentioning it illustrates the vast potential of Indian herbs like Santalum album that may share similar health benefits.
34) Discussion:
The discussion section in scientific papers interprets the results and contextualizes them within existing literature. In this study, discussions on the efficacy of Santalum album aids in understanding its role in traditional and modern medicine.
35) Developing:
Developing in this context relates to the process of research and advancement of knowledge in pharmacognosy. It indicates ongoing efforts to explore and validate the medicinal properties of plants like Santalum album.
36) Srivastava (Sri-vastava, Shrivastava, Shri-vastava):
Srivastava might refer to a collaborator or relevant scholarly figure within the field of study. Mentioning researchers establishes credibility by connecting current findings with established authorities in plant research.
37) Science (Scientific):
Scientific denotes the systematic study and methodology applied in conducting research. The scientific approach taken in this study emphasizes the rigor behind assessing Santalum album's properties and potential applications.
38) Narayana (Nara-ayana, Nara-yana):
Narayana might refer to a figure in context to the Ayurvedic tradition or a researcher. Associations with such names highlight the cultural significance and historical perspectives rooted in traditional Indian medicine.
39) Quality:
Quality pertains to the characteristics that define the effectiveness and safety of herbal extracts. This study assesses the quality of Santalum album extracts through various phytochemical and pharmacological analyses, ensuring their therapeutic viability.
40) Pouring:
Pouring in the laboratory context relates to the process of transferring liquids during experimentation. It reflects the meticulous nature of conducting scientific research, including the preparation and application of plant extracts in assays.
41) Tibetan:
Tibetan here refers to traditional medicine systems in Tibetan culture. Its mention alongside Ayurvedic practices indicates a broader interest in herbal remedies from different cultural perspectives, emphasizing a holistic approach to health.
42) Mishra (Misra):
Mishra likely refers to a researcher or scholarly figure contributing to the field of Ayurvedic medicine or pharmacognosy. Acknowledging individual contributions enhances the study's credibility and situates it within an academic framework.
43) Andhra (Amdhra):
Andhra refers to the specific region in India, known for its rich biodiversity and traditional medicinal practices. The significance lies in understanding the local context of Santalum album and its applications in regional medicine.
44) Sharman (Sarma, Sarman, Sharma):
Sharma could refer to either an author or a researcher in the field of Ayurvedic medicine. Acknowledging contributors is crucial for establishing the lineage of knowledge and recognizing efforts in advancing this area of research.
45) Powder:
Powder signifies the form in which plant materials are processed for extraction. In the study, powdered extracts of Santalum album are utilized for phytochemical analysis, emphasizing the importance of preparation in pharmacological studies.
46) Gold (Golden):
Golden may refer to specific colorimetric reactions indicating the presence of phytochemicals, particularly triterpenes, in the study’s assays. It highlights the relevance of visual indicators in confirming the presence of bioactive compounds.
47) Delhi:
Delhi, being a significant urban center, represents the convergence of traditional and modern medical research. Its mention underscores the importance of urban settings in facilitating research initiatives focused on herbal medicine.
48) Patil:
Patil may refer to a researcher or scholar contributing to the study's discourse on herbal medicine. Including names recognizes the collaborative nature of scientific research and the importance of individual expertise.
49) Glass:
Glass in laboratory contexts denotes the materials used for containing and processing chemical solutions. In the study, glassware signifies the controlled environment necessary for conducting accurate phytochemical and pharmacological assessments.
50) Tulsi:
Tulsi, or Ocimum sanctum, is a revered herb in Ayurveda known for its therapeutic properties. The mention signifies the cultural and medicinal importance of various botanical elements in promoting health and wellness within Indian medicine.
51) House:
House in this context may refer to the traditional or cultural setting where Ayurvedic practices and knowledge are preserved. It underscores the significance of community and environment in nurturing traditional medicinal wisdom.
52) Cina:
China highlights the geographical context of herbal medicine, emphasizing the global richness of medicinal plants. The mention denotes interest in cross-cultural studies of herbal efficacy and the influence of diverse traditional medicinal practices.
53) Lata:
Lata might refer to a researcher involved in studies regarding medicinal plants. Mentioning individual contributors adds the depth of collaboration in scientific research, indicating collective efforts to validate and explore herbal constituents.
54) Life:
Life in this context refers to health and vitality. The study investigates how Santalum album contributes to enhancing life quality through its medicinal properties, linking traditional uses with modern therapeutic practices.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Phytochemical, antioxidant, and antimicrobial studies of Santalum album bark.’. Further sources in the context of Science might help you critically compare this page with similair documents:
Santalum album, Flavonoid, Traditional medicine, Antioxidant activity, Phytochemical screening, Antimicrobial activity, In vitro, Zone of inhibition, Staphylococcus aureus, Ethanolic extract, Pseudomonas aeruginosa, Adaptogenic properties, Aspergillus niger, Antioxidant assay, IC50, Extraction method, Bacterial strain, Saponin, Alkaloid, Triterpenes, Phenolic compound, Qualitative phytochemical studies, Phytosterol.