Analysis of proximate composition and phytochemicals in Thuidium moss.

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Journal name: World Journal of Pharmaceutical Research
Original article title: Proximate composition and phytochemical analysis of solvent extract of thuidium tamariscellum (c.muell.)bosch. & sande-lac. a moss.
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Author:

Greeshma G.M. and Murugan K.


World Journal of Pharmaceutical Research:

(An ISO 9001:2015 Certified International Journal)

Full text available for: Proximate composition and phytochemical analysis of solvent extract of thuidium tamariscellum (c.muell.)bosch. & sande-lac. a moss.

Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research

Copyright (license): WJPR: All rights reserved


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Summary of article contents:

Introduction

Bryophytes, the oldest terrestrial plants, include mosses, liverworts, and hornworts, comprising approximately 22,000 species globally. Despite their widespread presence, the therapeutic potential of bryophytes has not been fully explored. This study investigates the phytochemical composition of Thuidium tamariscellum, a moss species found in Kerala, India. With the rise of multi-resistant pathogens that pose a significant global health threat, the demand for affordable and effective herbal remedies has intensified. This research highlights the necessity of understanding medicinal plants' phytochemical profiles to identify potential natural therapies.

Phytochemical Composition of Thuidium tamariscellum

The comprehensive qualitative analysis of various solvent extracts from Thuidium tamariscellum revealed a rich array of secondary metabolites, including alkaloids, flavonoids, glycosides, saponins, triterpenoids, coumarins, tannins, and phlobatannins. Among these, terpenoids were present in remarkable levels compared to other compounds. This suggests that Thuidium tamariscellum contains several bioactive compounds that could be explored for their pharmacological properties. The study employed various extraction methods, such as Soxhlet extraction, to ensure a thorough analysis of the plant's phytochemical components.

Extraction Methods and Analysis Techniques

The methodological approach included sequential extraction using chloroform, petroleum ether, ethyl acetate, ethanol, and water, followed by qualitative and quantitative analyses of the extracts. Specific tests were conducted to determine the presence of various phytochemicals, including flavonoids, alkaloids, terpenoids, saponins, and phenols. For instance, the presence of flavonoids was evaluated using an aluminum chloride method, while alkaloids were quantified by utilizing a specific reagent that formed a colored compound detectable by spectrophotometry. These established techniques allowed for a comprehensive overview of the chemical constituents of Thuidium tamariscellum.

Therapeutic Potential and Biological Activities

The results indicated that Thuidium tamariscellum possesses significant concentrations of various phytochemicals associated with multiple therapeutic activities. For instance, flavonoids and saponins found within the moss are recognized for their anti-cancer, anti-inflammatory, and antioxidant activities. Notably, terpenoids, which were the most abundant, are known for their extensive range of bioactivities, including antimicrobial and anticancer properties. Moreover, past studies on other bryophytes have reported similar health benefits, reinforcing the importance of further research into Thuidium tamariscellum as a potential source of novel medicinal compounds.

Conclusion

This study underscores the importance of investigating mosses like Thuidium tamariscellum for their phytochemical content and potential medicinal applications. The findings advocate for a deeper exploration of this moss in the context of traditional medicine, where it has been employed for various health-related purposes. With increasing concerns regarding drug resistance and emerging infectious diseases, the mining of natural compounds for new therapeutic agents is crucial. Continued research and isolation of active components could lead to significant advancements in herbal medicine and provide new pathways in treating debilitating health conditions.

FAQ section (important questions/answers):

What is the main focus of the study on Thuidium tamariscellum?

The study focuses on the phytochemical profiling of Thuidium tamariscellum, a moss species, to identify and quantify its secondary metabolites, which may have medicinal properties.

What solvents were used for extracting compounds from Thuidium tamariscellum?

The study utilized chloroform, petroleum ether, ethyl acetate, ethanol, and water for a continuous hot extraction method to analyze different solvent extracts of the moss.

What types of secondary metabolites were found in the moss?

Various secondary metabolites were identified, including alkaloids, flavonoids, saponins, triterpenoids, coumarins, tannins, and phlobatannins, suggesting potential medicinal properties.

What were the notable levels of phytochemicals quantified in the study?

The study reported significant concentrations of terpenoids, flavonoids, alkaloids, saponins, and phenols, indicating the moss's pharmacological potential.

Why are bryophytes like Thuidium tamariscellum ecologically important?

Bryophytes serve as ecological indicators, contribute to the ecosystem's health, and possess unique compounds that may offer therapeutic benefits.

What is the significance of finding lead molecules in the study?

Discovering lead molecules with novel chemical structures is crucial for developing new treatments for emerging infectious diseases, addressing the need for effective herbal compounds.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Analysis of proximate composition and phytochemicals in Thuidium moss.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Flavonoid:
Flavonoids are water-soluble plant pigments known for their antioxidant properties. They are significant in human health due to their potential protective roles against certain chronic diseases, including heart disease and cancer. In the study, flavonoids were identified as crucial components of 'Thuidium tamariscellum', reflecting its medicinal potential.

2) Phytochemical:
Phytochemicals are naturally occurring compounds found in plants that contribute to their color, flavor, and disease resistance. They play crucial roles in human health by providing various health benefits, including anti-inflammatory and antioxidant effects. The study highlights various phytochemicals present in 'Thuidium tamariscellum', emphasizing its therapeutic applications.

3) Murugan (Murukan):
Murugan refers to the researcher, specifically Murugan K., involved in the study of 'Thuidium tamariscellum'. His work is significant in the context of exploring the phytochemical and medicinal properties of bryophytes. Authors like Murugan are vital in linking traditional medicinal practices with scientific validation through research.

4) Species:
Species denote a group of organisms that can interbreed and produce fertile offspring under natural conditions. In the text, 'Thuidium tamariscellum' is highlighted as a species to explore its unique phytochemical profile, essential for understanding biodiversity, ecological interactions, and potential uses in traditional and modern medicine.

5) Sugar:
Sugars, particularly carbohydrates, serve as essential energy sources in living organisms. In the context of the study, sugar content in 'Thuidium tamariscellum' is evaluated to understand its nutritional value. This component may also influence the plant's physiological roles and ecological interactions in its habitat.

6) Table:
In research, a table serves as a systematic way to present data clearly and concisely. The tables in the study present the results of phytochemical analysis, allowing for quick comparison of different solvent extracts and their respective secondary metabolites, enhancing the scientific understanding of the findings.

7) Activity:
Activity in this context refers to the biological effects of certain compounds present in 'Thuidium tamariscellum'. The study emphasizes the pharmacological activity of its phytochemicals, such as antimicrobial effects, highlighting the importance of natural products in drug discovery and their potential applications in medicine.

8) Water:
Water is a universal solvent and vital for life, influencing plant growth and phytochemical extraction processes. In the study, water is one of the solvents used for extraction, essential for analyzing the phytochemical profile of 'Thuidium tamariscellum' and showcasing the plant's adaptability in varying environmental conditions.

9) Study (Studying):
The term study encompasses the comprehensive investigation and analysis of 'Thuidium tamariscellum', focusing on its phytochemical composition and potential medicinal properties. This research is crucial for revealing untapped resources in nature, potentially leading to the development of new therapeutic agents in medicine.

10) Cosmopolitan:
Cosmopolitan refers to species distributed worldwide under varied environmental conditions. 'Thuidium tamariscellum' is identified as a cosmopolitan moss, indicating its wide range of habitats. This trait may enhance its ecological importance and potential availability for research and utilization in various cultural medicinal practices.

11) Medicine:
Medicine relates to the science and practice of diagnosing, treating, and preventing diseases. The importance of 'Thuidium tamariscellum' in traditional medicine indicates its potential as a source of natural remedies. Understanding its phytochemical properties contributes significantly to the ongoing search for effective natural medicines.

12) Disease:
Disease refers to pathological conditions in living organisms. The text highlights the relevance of exploring 'Thuidium tamariscellum' as an alternative treatment source amid the emergence of antibiotic-resistant pathogens, emphasizing the urgent need for exploring herbal compounds in addressing global health challenges.

13) Cancer:
Cancer is a group of diseases characterized by uncontrolled cell growth. The study notes the presence of phytochemicals in 'Thuidium tamariscellum' that might have anticancer properties, underlining the relevance of traditional plant-based medicines in modern oncology and the search for novel therapeutic compounds.

14) Botany:
Botany is the scientific study of plants, encompassing their physiology, structure, ecology and taxonomy. The research involving 'Thuidium tamariscellum' contributes to botany by uncovering phytochemical properties of mosses, enhancing the understanding of plant diversity and potential uses in both traditional and contemporary medicine.

15) India:
India serves as the geographical context for the study, providing rich biodiversity, particularly in its flora, including mosses like 'Thuidium tamariscellum'. The exploration of local plant species for their medicinal properties reflects India's traditional health practices and the potential for scientific advancements derived from its natural resources.

16) Alam (Alaṁ):
Alam signifies a researcher or author whose work might have been cited or referenced in the study. The inclusion of studies by Alam emphasizes the interconnectedness of research in understanding the biological activities of plants, highlighting collaboration and cumulative knowledge in the field of phytochemistry.

17) Drug:
A drug is a substance used to diagnose, cure, treat, or prevent disease. The study emphasizes the significance of identifying natural compounds in 'Thuidium tamariscellum' as potential drugs, advocating for the importance of herbal research as an essential aspect of drug discovery in combating healthcare challenges.

18) Pharmacological:
Pharmacological pertains to the study of drug effects and mechanisms in biological systems. The assessment of 'Thuidium tamariscellum' in terms of pharmacological activity signifies the importance of examining its phytochemicals for their therapeutic potentials, catering to the modern demand for effective medicinal agents.

19) Antibiotic (Antibacterial):
Antibacterial refers to substances that inhibit bacterial growth or kill bacteria. The study mentions the antibacterial activities of 'Thuidium tamariscellum', demonstrating the potential of this moss in developing treatments against resistant bacterial strains, addressing an increasing public health concern globally.

20) Discussion:
Discussion in research contexts refers to the interpretation and analysis of study findings. The discussion section in this study likely elaborates on the implications of the phytochemical analysis of 'Thuidium tamariscellum', integrating results with existing knowledge while suggesting future directions for research in this area.

21) Toxicity:
Toxicity denotes the degree to which a substance can cause harm to organisms. Understanding the toxicity level of phytochemicals in 'Thuidium tamariscellum' is crucial for assessing its safety for medicinal use. This evaluation is essential in developing trustworthy herbal therapies devoid of adverse effects.

22) Habitat:
Habitat refers to the natural environment in which a species lives. 'Thuidium tamariscellum' is noted for its distribution in various habitats, including rocks and leaf litter. Understanding its habitat is crucial for conservation efforts and for exploring its ecological roles and evolutionary adaptations.

23) Kerala:
Kerala, a state in southern India, is highlighted as the geographic location where 'Thuidium tamariscellum' is found. The biodiversity of Kerala and its cultural implications in traditional medicine provide context for the study, revealing local practices and knowledge surrounding the use of mosses in healthcare.

24) Insect:
Insect refers to a class of arthropods that may have interactions with plants, including potential roles as pests or pollinators. The study might touch upon the influence of certain phytochemicals in 'Thuidium tamariscellum' that could repel insect activity, providing ecological benefits amidst plant growth.

25) Indian:
Indian pertains to anything related to India. The study's context in India highlights the significance of local plants in traditional practices, exploring how indigenous knowledge intersects with scientific inquiries into the therapeutic properties of 'Thuidium tamariscellum', reflecting cultural wisdom in modern research.

26) Blood:
Blood is a vital fluid in human physiology, often associated with health indicators. The study might examine the effects of phytochemicals found in 'Thuidium tamariscellum' on blood-related conditions, showcasing the potential of these compounds in promoting health and mitigating diseases associated with blood anomalies.

27) Cina:
China represents a geographical context where traditional medicine extensively utilizes various plants, including bryophytes. The mention of Chinese medicinal practices regarding mosses like 'Polytrichum' indicates a historical perspective on the relevance of such plants globally and establishes a wider foundation for understanding their medicinal properties.

28) Hela (Helá):
Hela refers to a specific type of cell line often used in cancer research. The reference to HeLa cells suggests that some of the phytochemicals isolated from 'Thuidium tamariscellum' may have undergone testing for anticancer properties on this cell line, emphasizing the study's relevance in cancer pharmacology.

29) Hair:
Hair relates to human physiology, often associated with beauty and health. The text mentions mosses previously used for hair growth stimulation, indicative of ‘Thuidium tamariscellum’s’ potential applications in personal care products and traditional remedies for enhancing hair health and promoting hair growth.

30) Burning (Burn, Burned, Burnt):
Burn refers to a type of injury caused by heat, chemicals, or radiation. The study references the traditional use of certain mosses to heal wounds, bruises, and burns, emphasizing the importance of exploring natural remedies in developing effective treatments for skin injuries and enhancing recovery.

Other Science Concepts:

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Discover the significance of concepts within the article: ‘Analysis of proximate composition and phytochemicals in Thuidium moss.’. Further sources in the context of Science might help you critically compare this page with similair documents:

Flavonoid, Medicinal properties, Traditional medicine, Qualitative analysis, Phytochemical analysis, Secondary metabolite, Biological properties, Tannin, Bioactive compound, Herbal Compound, Cytotoxic effect, Nutrient content, Saponin, Alkaloid, Terpenoid, Extraction procedure, Coumarin, Glycoside, Solvent extract.

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