Effect of fenugreek on hematology and biochemistry in ewes.
Journal name: World Journal of Pharmaceutical Research
Original article title: Effect of fenugreek seeds (trigonella foeum graecuml.) on heamatological and biochemical performance of pregnant and non pregnant ewes
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
This page presents a generated summary with additional references; See source (below) for actual content.
Original source:
This page is merely a summary which is automatically generated hence you should visit the source to read the original article which includes the author, publication date, notes and references.
Samia A. A. Hassan, Sania A. I. Shaddad, A. K. Muddathir, Amna E. H. Mohammed
Download the PDF file of the original publication
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Effect of fenugreek seeds (trigonella foeum graecuml.) on heamatological and biochemical performance of pregnant and non pregnant ewes
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr20165-6175
Copyright (license): WJPR: All rights reserved
Summary of article contents:
Introduction
Fenugreek seeds (Trigonella foenum-graecum) are a significant source of nutrition and medicinal properties, historically utilized to enhance appetite and milk production, as well as to stimulate various hormonal levels. This research aimed to investigate the biochemical and hematological impacts of oral administration of fenugreek seeds on both pregnant and non-pregnant ewes. The study specifically focused on important blood parameters and hormone levels to understand how fenugreek supplementation could influence reproductive efficiency during pregnancy.
Hematological Effects of Fenugreek Administration
The study found a notable increase in hemoglobin (Hb) concentrations and red blood cell (RBC) counts in ewes receiving fenugreek supplementation compared to the control group. Specifically, the hemoglobin levels in treated ewes were significantly higher, suggesting that the protein content in fenugreek positively impacted the blood parameters. However, while the white blood cell (WBC) counts remained within normal limits, the packed cell volume (PCV) showed a significant increase, indicating improved oxygen transport capacity in the bloodstream due to fenugreek administration. These hematological changes may contribute to better metabolic efficiency in pregnant ewes.
Biochemical Parameters and Hormonal Impact
Serobiochemical evaluations revealed no significant changes in total protein, albumin, or bilirubin levels among the groups, although enzymes such as SGPT and SGOT increased in treated ewes. Furthermore, a marked decrease in serum progesterone was observed during the treatment period for the non-pregnant group, which may correlate with fenugreek's influence on the endocrine system, specifically pituitary hormone secretion. Such hormonal fluctuations are critical to understanding the reproductive implications of fenugreek ingestion, particularly during pregnancy.
Adverse Effects on Pregnancy
Contrary to expectations, fenugreek supplementation appeared to have negative implications for pregnant ewes, particularly regarding progesterone levels. The significant decrease in progesterone raised concerns about possible abortifacient effects during the late stages of pregnancy. This decline in hormone levels, influenced by the nutitional composition of fenugreek, could lead to increased uterine contractions and pose risks to fetal survival. Additionally, the study indicated that, while fenugreek might enhance general health parameters, its effect on vital hormone levels must be carefully assessed in future studies, especially for pregnant animals.
Conclusion
The findings from this research underscored the dual role of fenugreek seeds as a nutritional supplement while also raising important concerns regarding their reproductive effects in ewes. The hematological improvements observed could be beneficial, but the adverse impact on hormonal balance, particularly progesterone, signifies that careful consideration must be given when using fenugreek in breeding programs. Future studies should focus on elucidating the safe doses for pregnant animals and exploring the underlying mechanisms of fenugreek's effects on reproductive health to ensure the welfare of both ewes and their offspring.
FAQ section (important questions/answers):
What is the purpose of the study on fenugreek seeds?
The study aimed to investigate the effects of oral administration of fenugreek seeds on the biochemical and haematological performance of both pregnant and non-pregnant ewes.
How were the ewes divided for the experiment?
Twenty-eight Sudanese desert ewes were randomly divided into two groups: a control group that received no treatment and a treatment group that received 2.5 g/kg body weight of fenugreek seeds daily for seven weeks.
What significant findings were observed in haematological parameters?
The treatment group showed significantly higher hemoglobin and red blood cell counts compared to the control group, indicating improved haematological performance due to fenugreek supplementation.
What were the biochemical changes noted in the ewes?
The study noted increased activities of SGPT, SGOT, and ALP in the treatment group, with no significant changes in total protein, albumin, or bilirubin levels.
How did fenugreek seeds affect progesterone levels in ewes?
The administration of fenugreek seeds led to a significant decrease in serum progesterone levels in non-pregnant ewes, potentially due to influences on hormonal secretion.
What implications do the study findings have regarding pregnancy?
The results suggest that fenugreek seeds may adversely affect reproductive potential in pregnant ewes, potentially leading to complications such as reduced progesterone levels and increased risk of abortion.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Effect of fenugreek on hematology and biochemistry in ewes.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Pregnant:
This term refers to the physiological state of female ewes that are carrying developing offspring. In the study, pregnant ewes were specifically researched to understand the effects of Fenugreek on their health parameters, affecting maternal blood chemistry and reproductive outcomes, which are crucial for successful breeding in livestock management.
2) Fenugreek:
Fenugreek, scientifically known as Trigonella foenum-graecum, is a significant leguminous plant utilized for its nutritional and medicinal properties. The study investigates its biochemical and hematological effects when administered to both pregnant and non-pregnant ewes, emphasizing its potential role in enhancing reproductive health and overall well-being of livestock.
3) Table:
Tables in the context of this study serve to systematically present data regarding the observed effects of Fenugreek on various biological parameters. They allow for a clear comparison between control and treated groups, enabling quick assessment of statistical significance and aiding in the interpretation of experimental results.
4) Animal:
The study involved Sudanese desert ewes as the animal model, which is vital for understanding the physiological effects of Fenugreek in a veterinary context. Accurate assessment of biologically relevant parameters in these animals contributes to improvements in animal health care, nutrition, and reproductive management in veterinary practice.
5) Observation:
Observations constituted critical parts of the experimental methodology, gathering data on hematological and biochemical changes in pregnant and non-pregnant ewes. Accurate observations helped ascertain the effects of Fenugreek treatment and informed conclusions about its efficacy and safety in veterinary applications, as well as animal husbandry practices.
6) Blood:
Blood analysis is central to evaluating health and nutritional status in the study. Key parameters such as Hemoglobin concentration, Red Blood Cell count, and White Blood Cell count are measured to understand the physiological impacts of Fenugreek on the ewe's overall health and metabolic functions during pregnancy.
7) Toxicology:
Toxicology pertains to the study of adverse effects of substances on organisms. In this study, toxicological assessments related to Fenugreek help ensure that its utilization does not lead to harmful effects in ewes, especially regarding reproductive health, highlighting the importance of safe administering for animal welfare.
8) Medicine:
The relevance of medicine in the context of the study relates to the therapeutic properties of Fenugreek. By investigating its effects on pregnant ewes, the study aims to contribute to veterinary medicine by identifying potential ways to improve reproductive outcomes and overall health using natural dietary supplements.
9) Study (Studying):
This study investigates the specific effects of Fenugreek on pregnant and non-pregnant ewes, aiming to gather empirical evidence on its benefits and side effects. It seeks to enhance existing knowledge of veterinary practices and contribute to the development of nutritional protocols for livestock management.
10) Pharmacology:
Pharmacology is the branch of science concerned with the effects of drugs and their mechanisms of action. This study explores the pharmacological properties of Fenugreek seeds to determine its effectiveness and safety as a supplement for pregnant ewes, influencing veterinary treatment protocols and livestock health strategies.
11) Pharmacological:
Pharmacological effects refer to the specific biological responses elicited by Fenugreek in ewes, as studied through various biochemical and hematological metrics. Understanding these effects is crucial for determining safe dosages and the potential for utilizing Fenugreek in livestock feeding regimens to enhance health outcomes.
12) Performance:
Performance in this context refers to the physiological and reproductive outcomes observed in the ewes subjected to Fenugreek treatment. The study assesses various performance indicators, such as blood health and reproductive efficiency, to evaluate the effectiveness of Fenugreek in improving overall health in these animals.
13) Discussion:
The discussion section of the study analyzes the collected data, interpreting the results within the context of existing research. It evaluates the implications of Fenugreek on ewes’ health and offers insights into the physiological mechanisms at play, informing future research directions and practical applications in livestock management.
14) Knowledge:
Knowledge in this study pertains to the understanding gained regarding the impact of Fenugreek on pregnant ewes. This includes insights into its biochemical effects, the dynamics of animal nutrition, and implications for veterinary practices, ultimately contributing to more informed decisions in livestock health management.
15) Substance:
Substance here refers to Fenugreek as a natural ingredient administered to ewes. Its biochemical properties and nutritional composition play significant roles in the study's outcomes, helping to ascertain the substance's viability as a supplementary feed to enhance health and reproductive performance in livestock.
16) Hygiene (Hygienic):
Hygienic conditions are critical in livestock studies, ensuring that the animals are cared for in a clean environment to prevent disease and stress. In this study, maintaining hygienic practices contributes to accurate examination of the effects of Fenugreek on health parameters without the confounding influence of pathogens.
17) Labour (Labor):
Labour, in this context, refers to the physiological processes involved in the birthing of offspring in ewes. The study examines how Fenugreek may influence factors related to labor, such as hormone levels and uterine contractions, which are key for understanding reproductive health in the studied animal population.
18) Water:
Water is essential for animal health, impacting overall well-being and physiological functioning. In the study, ensuring ewes have ad libitum access to water underscores its importance in the assessment of the effects of Fenugreek supplementation, as adequate hydration is vital for accurate physiological measurements.
19) Cutan:
Sudan is the geographical context of the study, which examines local breeds of ewes. Understanding the effects of Fenugreek within this specific environment aids in tailoring agricultural practices and nutritional strategies that comply with local conditions, enhancing livestock productivity and sustainability in Sudanese agriculture.
20) Food:
Food in this study refers to the diet provided to the ewes, including the supplementation with Fenugreek. Investigating how dietary changes affect health parameters helps develop improved feeding strategies that enhance the nutritional status and productivity of livestock.
21) Diet:
Diet pertains to the nutritional regimen fed to the ewes during the study, directly influencing their health and reproductive outcomes. The research focuses on how incorporating Fenugreek into their diet can yield biochemical and hematological benefits, providing insights for dietary formulations in livestock management.
22) Milk:
Milk production is a critical outcome in breeding ewes, researched in relation to Fenugreek supplementation. The study's implications for enhancing milk yield through improved maternal health and nutrition may have significant value for dairy producers, emphasizing the importance of feed ingredients like Fenugreek in reproductive strategies.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Effect of fenugreek on hematology and biochemistry in ewes.’. Further sources in the context of Science might help you critically compare this page with similair documents:
Trigonella foenum-graecum, Pharmacological properties, Statistical analysis, Control group, Oral administration, Physiological anemia, Progesterone Profile, Pregnant ewes, Hormonal production, Fenugreek seed.