Effect of Trigonella foenum-graecum on hormones in Sudanese sheep
Journal name: World Journal of Pharmaceutical Research
Original article title: The effect of trigonella-fonum-graecum on reproductive hormones in sudanese desert sheep
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Samia A. A. Hassan, Sania A. I. Shaddad, A. K. Muddathir, A. A. ElSadig,Hala E. Ahmed and Nuha M. E. Agbana
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World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: The effect of trigonella-fonum-graecum on reproductive hormones in sudanese desert sheep
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr20166-6198
Copyright (license): WJPR: All rights reserved
Summary of article contents:
Introduction
The study investigates the effects of Trigonella foenum-graecum (fenugreek) on reproductive hormones in non-pregnant Sudanese desert sheep. Fenugreek, an annual herb belonging to the leguminous family, is commonly used for various purposes such as feed, spice, and traditional remedies. The research was conducted with fourteen ewes that were synchronized to induce estrus and then divided into two groups for treatment with fenugreek. The primary aim was to analyze the progesterone levels and oestrus cycles following the administration of fenugreek at a specific dosage.
The Role of Fenugreek on Reproductive Hormones
The findings revealed a gradual decrease in progesterone levels across three consecutive estrus cycles in ewes treated with fenugreek. The control group, which received no treatment, displayed higher progesterone profiles compared to the treated group. This result signifies fenugreek’s potential impact on reproductive hormone modulation. Fenugreek seeds contain phytoestrogens and other compounds that can influence hormonal regulation, possibly affecting the secretion of gonadotropins that play a critical role in reproductive processes.
Synchronization and Induction of Estrus
The study successfully induced and synchronized the estrus cycles in the ewes using hormonal treatments with CIDR (Controlled Internal Drug Release) and PMSG (Pregnant Mare Serum Gonadotropin). The ewes exhibited signs of estrus within 48 to 72 hours post-treatment, suggesting that the hormonal synchronization protocol was effective. Monitoring estrus behavior in the ewes provided insights into their reproductive status, while the obtained progesterone profiles facilitated an understanding of the impacts of dietary supplementation with fenugreek.
Examination of Progesterone Profiles Across Cycles
Throughout the experimental period, significant declines in progesterone levels were noted across all three measurement days (D1, D2, and D3) in the fenugreek-treated group. The decreasing trend could indicate an enhanced effect of fenugreek on the pituitary gland's secretion of hormones that suppress progesterone synthesis, thus supporting the induction of estrus. This change in progesterone levels is vital for understanding the hormonal dynamics within the ewes and the role of dietary influences on reproductive functions.
Conclusion
The study concludes that fenugreek positively influences reproductive hormones in Sudanese desert sheep by modulating progesterone levels and affecting estrus cycles. The synchronization of estrus and the resulting variations in hormone profiles suggest that fenugreek could be utilized as a dietary supplement to enhance reproductive efficiency in sheep. Future research may aim to explore the long-term effects and mechanisms of fenugreek on reproductive health to optimize its application in veterinary practices and sheep farming.
FAQ section (important questions/answers):
What was the aim of the study on Trigonella foenum-graecum?
The study aimed to investigate the effects of Trigonella foenum-graecum on the estrous cycle and progesterone levels in Sudanese desert sheep.
How many ewes were involved in the experimental study?
Fourteen non-pregnant ewes were synchronized and divided into two groups for the study.
What dosage of Trigonella foenum-graecum was administered to the ewes?
The ewes in the treatment group received an oral dose of 2.5 g/kg body weight of Trigonella foenum-graecum.
What method was used to measure progesterone levels in the study?
Progesterone levels were measured using the Radioimmunoassay technique, which involves comparing sample progesterone with a labeled standard.
What were the results regarding progesterone levels after treatment?
Progesterone levels significantly decreased throughout the three consecutive days of measurement, suggesting a possible effect of Trigonella on hormonal fluctuations.
What conclusion can be drawn about Trigonella's effect on sheep?
The study concluded that Trigonella foenum-graecum may influence reproductive hormone levels and estrous cycle synchronization in sheep.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Effect of Trigonella foenum-graecum on hormones in Sudanese sheep”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Animal:
The term 'animal' refers to the living organisms being studied in this research, specifically 14 non-pregnant ewes. Understanding animal physiology, behavior, and welfare is crucial in veterinary science and agriculture. The animals serve as subjects to investigate the effects of Trigonella foenum-graecum on reproductive hormones, contributing to knowledge in veterinary medicine and animal husbandry.
2) Fenugreek:
Fenugreek, or Trigonella foenum-graecum, is a herb used in this study for its potential effects on reproductive hormones. The plant is known for various medicinal properties and is used in traditional remedies. Its significance lies in its ability to influence hormonal profiles in livestock, potentially improving reproductive performance and animal health.
3) Table:
In the context of this research, 'table' refers to the organized presentation of data, specifically hormone level measurements over the study period. Tables are essential in scientific literature as they facilitate clear communication of results, allowing readers to easily understand and compare findings related to progesterone levels in ewes affected by fenugreek.
4) Sign:
The term 'sign' in this study relates to observable indicators of the estrous cycle in ewes, such as behavioral changes and physiological responses. Identifying these signs is critical for effective breeding management. Recognizing estrus signs can help improve reproductive efficiency in animal husbandry, influencing breeding schedules and outcomes.
5) Study (Studying):
The term 'study' encompasses the entire research undertaking examining the effects of fenugreek on reproductive hormones in sheep. It reflects the methodology, results, and analysis aimed at uncovering new insights in veterinary science. Scientific studies are crucial for expanding knowledge, guiding best practices, and improving animal husbandry strategies.
6) Family:
In biological classification, 'family' refers to a group of related organisms. In this context, fenugreek belongs to the Leguminosae family. Understanding the family classification aids in recognizing the genetic and functional relationships among species, as well as the specific characteristics prevalent within that family.
7) Water:
Water is essential for all living organisms, including the ewes involved in the study. Adequate hydration is critical for various physiological processes, including hormonal balance and overall health. In animal husbandry, access to fresh water is vital for productivity, reproductive success, and the welfare of farm animals.
8) Milk:
The term 'milk' relates to reproductive hormones in female sheep and their significance in lactation and overall reproductive efficiency. Understanding milk production in relation to hormonal levels is important for optimizing breeding programs. The health and hormonal status of ewes can directly impact milk yield and quality in dairy farming.
9) Pharmacology:
Pharmacology is the study of drugs and their effects on biological systems. In this research, pharmacology is relevant as it explores the impact of fenugreek, a natural substance, on reproductive hormones. Understanding pharmacological principles helps in evaluating how plant-derived compounds can influence animal physiology and therapeutic strategies in veterinary medicine.
10) Toxicology:
Toxicology examines the adverse effects of substances on living organisms. In this context, the relevance lies in assessing the safety of using fenugreek as a supplement in sheep. Evaluating potential toxic effects is crucial in veterinary practices, ensuring that treatments enhance health without causing harm to the animals.
11) Medicine:
Medicine pertains to the science and practice of diagnosing and treating health issues. In the study, it relates to veterinary medicine and the use of natural compounds like fenugreek to influence reproductive health in sheep. Advances in veterinary medicine can lead to improved animal welfare and productive outcomes in agriculture.
12) Pregnant:
The term 'pregnant' refers to the state of carrying offspring, significant in studying reproductive hormones. The research primarily focuses on non-pregnant ewes, emphasizing hormonal changes connected to estrus cycles. Understanding pregnancy and its hormonal influences is fundamental in reproductive biology and breeding management in livestock.
13) Field:
The term 'field' in this context refers to veterinary and agricultural studies concerning animal behavior, health, and reproduction. Field studies are essential for applying research findings in practical settings, contributing to knowledge that enhances livestock management practices, breeding efficiency, and overall farm productivity.
14) Blood:
Blood is vital for transporting hormones and nutrients throughout an animal's body. In this study, blood samples are collected to measure progesterone levels. Monitoring these levels is crucial for understanding reproductive status and health in sheep, which is important for effective breeding management in livestock operations.
15) Trigonella foenum-graecum:
Trigonella foenum-graecum, or fenugreek, is the primary subject of this research. It is explored for its effects on reproductive hormones in sheep. Understanding its botanical and pharmacological properties can provide insights into natural ways to enhance reproductive performance, improving animal welfare and productivity in the agriculture sector.
16) Calculation:
Calculation is relevant in the analysis of data obtained during the study, particularly in determining hormone levels from measured samples. Accurate calculations are essential for statistical analysis, allowing researchers to derive meaningful conclusions from their findings and evaluate the effectiveness of treatments applied during the research.
17) Measurement:
Measurement refers to the quantitative determination of hormone levels in the serum of sheep. It is a crucial aspect of the study, enabling researchers to track changes in progesterone levels over time. Accurate measurements are vital for validating the effects of fenugreek and ensuring reliable results in veterinary research.
18) Observation:
Observation is key in scientific research for identifying changes in behavior, physiological responses, and hormone levels. In this study, observing estrous signs in ewes corresponds to hormonal fluctuations caused by fenugreek supplementation. Observational data contribute significantly to understanding reproductive cycles and the effectiveness of various treatments.
19) Discussion:
The discussion section synthesizes findings, exploring their implications and relevance to existing knowledge. It allows researchers to interpret data from the study and relate it to previous research. This exchange of ideas fosters growth in scientific understanding and informs future studies and practical applications in veterinary medicine.
20) Buffalo (Buffaloes):
Buffaloes are mentioned in relation to fenugreek's effects on hormones, highlighting its broader implications in livestock management. Their physiology and hormonal responses can provide insights similar to those of sheep. Understanding how different ruminants respond to dietary changes is essential for generalizing findings across species in animal science.
21) Flavonoid:
Flavonoids are plant compounds found in fenugreek with potential health benefits. They are believed to act as phytoestrogens, influencing hormonal activities. This relevance in the study emphasizes exploring natural supplements that can modulate reproductive functions and improve the reproductive health of livestock, offering an alternative to synthetic hormones.
22) Activity:
Activity refers to physiological responses or actions, particularly hormone secretion in this study. The term is relevant in describing the effects of fenugreek on reproductive hormone dynamics in sheep. Enhancing or modulating hormonal activity can play a crucial role in reproductive efficiency and successful breeding programs.
23) Dividing:
Dividing is relevant in the context of categorizing the experimental sheep into control and treatment groups. This strategic division ensures that the study accurately assesses the effects of Trigonella foenum-graecum on hormonal levels. Properly defining groups is fundamental for statistical analysis and drawing valid conclusions.
24) Channel:
In this research, 'channel' may refer to pathways or methods used to measure and analyze hormone levels or communicate findings. Clear information channels are critical in presenting research to the scientific community, ensuring that results are accessible and understandable, thereby facilitating collaboration and further study.
25) Quality:
Quality pertains to the effectiveness and reliability of the results obtained from the study. Understanding the quality of hormone measurements, the reliability of fenugreek's effect on reproduction, and the implications for animal health are crucial for informing best practices in veterinary medicine and livestock management.
26) Disease:
Disease relates to health issues that may affect reproductive performance in sheep. Understanding how fenugreek influences hormone levels can help mitigate reproductive diseases, improving overall herd health and productivity. This relevance underscores the importance of research aimed at enhancing animal welfare through effective dietary interventions.
27) Powder:
Powder refers to the form in which fenugreek is consumed by the sheep during the study. The choice of administration, whether in powder form or otherwise, impacts absorption and effectiveness in influencing reproductive hormones. Different forms of herbal treatments can alter their bioavailability and physiological effects.
28) Desire:
Desire may refer to the reproductive drive observed in breeding animals. In this study, understanding sexual desire follows hormonal changes induced by treatment with fenugreek. Recognizing the indicators of desire is important in managing successful breeding programs and optimizing reproductive outcomes in livestock.
29) Aroma (A-roma):
Aroma describes the distinctive smell of fenugreek. The aroma may contribute to its acceptance by animals and its usage in feed. Understanding sensory attributes can impact how dietary supplements are formulated and administered to livestock, potentially affecting feeding behaviors and health outcomes in animal husbandry.
30) Cutan:
Sudan is relevant as the geographical location of this research, which may influence factors such as climate, local livestock breeding practices, and availability of fenugreek. Understanding regional variations is crucial in assessing the applicability of research findings to local agricultural practices and enhancing agricultural sustainability.
31) Hala:
Hala refers to one of the authors contributing to the study, emphasizing collaboration in scientific research. The involvement of multiple authors from different disciplines enhances the rigor of the research through shared expertise, contributing to a comprehensive understanding of the effects of fenugreek on reproductive hormones.
32) Mani:
Mani is mentioned in the study, likely referring to another author or researcher. Contributions by various individuals highlight the collaborative nature of scientific research, where diverse expertise is essential in addressing complex issues in animal health and reproductive efficiency. This collective effort enhances the validity and applicability of the findings.
33) Diet:
Diet refers to the nutritional regimen of the sheep involved in the study, specifically regarding fenugreek supplementation. Understanding how diet influences hormone levels is critical in improving breeding outcomes, as optimal nutrition is essential for reproductive health and efficiency in livestock production.
34) Post:
Post typically relates to the period following a specific event, such as treatment or estrus induction in this research. Understanding the post-treatment effects on hormone levels helps evaluate the efficacy of interventions, guiding future research and improvements in breeding strategies for livestock.
35) Drug:
Drug, in this context, may refer to the natural compound, fenugreek, being studied for its therapeutic effects on reproductive hormones. Investigating the benefits and mechanisms by which herbal drugs influence animal health is essential for integrating alternative treatments into veterinary practices, enhancing overall herd performance.
36) Male:
Male refers to the gender of animals whose reproductive behaviors and hormone responses may be influenced by the dietary inclusion of fenugreek. Understanding male reproductive physiology in relation to female counterparts provides insights into overall herd management and can enhance breeding strategies for increased productivity.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Effect of Trigonella foenum-graecum on hormones in Sudanese sheep’. Further sources in the context of Science might help you critically compare this page with similair documents:
Trigonella foenum-graecum, Flavonoid, Nutritive value, Statistical analysis, Control group, Reproductive hormones, Oxytocic effect, Hormonal Assay, Dosing regimen, Serum sample, Progesterone Profile, Oestrus Cycle, CIDR Device, Animal Housing.