Derma sticks of Abrus precatorius for gynecological skin infections.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Derma sticks of Abrus precatorius for gynecological skin infections.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Abrus precatorius:
Abrus precatorius, commonly known as rosary pea, is a climber that possesses significant pharmacological properties, particularly anti-bacterial and anti-fungal activities. In this context, its extracts are utilized in the formulation of medicated derma sticks aimed at treating gynecological skin infections caused by Candida albicans, demonstrating its relevance in herbal medicine and modern pharmaceutical applications.

2) Irritation:
Irritation refers to the inflammatory response of the skin to substances, which may manifest as redness, itching, or swelling. In the study, primary skin irritation tests were performed to evaluate the safety of the medicated derma sticks developed, ensuring that their application did not cause adverse reactions like erythema or edema in subjects.

3) Drug:
A drug is a substance used for medical purposes to diagnose, treat, or prevent disease. In this research, the primary drug utilized is derived from Abrus precatorius, aimed at treating gynecological skin infections. The study focuses on its formulation and effectiveness as a topical treatment, emphasizing its therapeutic potential.

4) Table:
Tables are structured data representations used in scientific writing to organize complex information clearly. In this study, tables summarize the formulations of medicated derma sticks, their evaluations regarding weight, thickness, and their antimicrobial properties, facilitating easy comparison and reference for the results obtained during the research.

5) Male:
In the context of the research, 'male' refers to the gender of animal subjects used in preclinical studies for testing skin irritation. Various males, rabbits, and guinea pigs were employed to ensure that the evaluation of the medicated stick's safety was thorough and inclusive of different biological responses to the formulations.

6) Medium:
The term medium typically denotes the substance in which organisms are cultivated or tested. In this study, Sabouraud’s dextrose agar served as the medium for growing Candida albicans, allowing researchers to assess the antimicrobial activity of the formulated medicated sticks against this pathogenic yeast in the antimicrobial study.

7) Activity:
Activity in this context refers to the bioactive properties of Abrus precatorius, specifically its anti-bacterial and anti-fungal actions. The study focuses on evaluating the activity of these derived compositions in combating infections, showcasing the relevance of herbal compounds in therapeutic formulations and their effectiveness against microbial pathogens.

8) Water:
Water is a critical solvent used in pharmaceutical formulations, including the preparation of medicated sticks. In this study, purified water was utilized to dissolve compounds such as sodium lauryl sulfate and propylene glycol, contributing to the uniform mixing of ingredients and the overall stability of the final product intended for topical application.

9) Edema (Oedema):
Edema refers to the accumulation of fluid in tissues, often indicating inflammation or irritation. The evaluation of edema during skin irritation tests is crucial in this research as it helps ascertain the safety of the medicated sticks made from Abrus precatorius, ensuring that the formulation does not provoke adverse skin reactions.

10) Heating:
Heating is a technique used in the preparation of medicated sticks, where ingredients are melted to create a uniform mixture. This process ensures the effective incorporation of drugs like Abrus precatorius into the formulation, allowing for an even distribution throughout the product, which is vital for achieving the desired therapeutic effectiveness.

11) Itching:
Itching is a common symptom associated with skin inflammation and infections, particularly in conditions such as candidiasis. The medicated sticks developed in the study aim to relieve itching caused by gynecological skin infections, thereby enhancing patient comfort and compliance with treatment protocols in women experiencing these distressing symptoms.

12) Study (Studying):
The study refers to the systematic investigation conducted to explore the formulation, safety, and efficacy of medicated sticks containing Abrus precatorius. Through various phases of research, including preparation, characterization, microbial testing, and skin irritation assessments, the study aims to validate the potential of these herbal-based products for treating skin infections.

13) Antibiotic (Antibacterial):
Anti-bacterial denotes the ability of a substance to inhibit or kill bacterial growth. In this research, the anti-bacterial properties of the medicated sticks formulated with Abrus precatorius are explored, highlighting its potential in treating skin infections caused by bacteria and ensuring effective therapeutic outcomes for patients.

14) Solapur:
Solapur is a city in Maharashtra, India, where one of the collaborating colleges involved in this research—College of Pharmacy, Solapur University—is located. The mention of Solapur emphasizes the geographical diversity of the research institutions and their contribution to the study of herbal medicines and pharmaceutical advancements.

15) Species:
In a biological context, species refers to a group of organisms capable of interbreeding. This study addresses the species Candida albicans specifically, which is responsible for candidiasis. Understanding the behavior and pathogenicity of such species is critical for developing effective treatments using herbal remedies like Abrus precatorius.

16) Animal:
In research, the term animal usually pertains to subjects used for preclinical testing of formulations. This study utilized rabbits and guinea pigs to assess the safety and potential irritation effects of the medicated derma sticks, ensuring that results are applicable to human use by observing animal responses.

17) Life:
Life signifies the biological existence of living organisms, which, in the context of this study, includes humans and animals tested for skin irritation. The investigation into the medicated sticks' effects on life is essential for ensuring product safety and efficacy, ultimately contributing to health improvement for affected individuals.

18) Burning sensation:
Burning sensation is a distressing symptom commonly experienced in skin conditions. The formulation of medicated sticks aims to alleviate such sensations caused by infections. Understanding this symptom is key for evaluating the effectiveness of treatments, ensuring that patients experience relief and enhanced comfort during the therapeutic process.

19) Container:
Container refers to the packaging or holder for the medicated derma sticks once prepared. The choice of container is significant for protecting the formulation from contamination and preserving its integrity, which is critical for maintaining its therapeutic properties and ensuring safe application by users.

20) Observing:
Observing involves closely monitoring subjects or samples during experiments. In this study, observing the skin reactions of animal subjects and human volunteers is crucial for assessing the irritancy of the medicated sticks, thereby providing essential data to determine the product's safety for topical use.

21) Pratima:
Pratima references one of the authors involved in the research study. Author contributions are vital for the collaborative nature of scientific research, showcasing the collective effort of individuals in the discovery and development of effective pharmaceutical products, in this case, the medicated sticks for skin infections.

22) Burning (Burn, Burned, Burnt):
Burning, as a term, describes a painful sensation often associated with skin irritation or inflammation. The research on medicated sticks aims to address burning sensations experienced by patients due to infections, thereby targeting the relief of such discomfort through effective topical treatments derived from Abrus precatorius.

23) Surface:
Surface refers to the outer layer of the skin where topical applications are made. Proper formulation and application of the medicated sticks are essential to ensure they effectively interact with the surface, providing the necessary therapeutic effect directly where the infection or irritation occurs for optimal healing.

24) Powder:
Powder signifies the powdered form of Abrus precatorius used in the formulation of medicated sticks. The powdered herb allows for easier incorporation into the mixture, ensuring even distribution and enhancing its therapeutic potential, thereby maximizing the effectiveness of the drug in treating gynecological skin infections.

25) Patil:
Patil refers to one of the contributors to the research, indicating the collaborative authorship within the study. Recognition of each author's role emphasizes the importance of teamwork in advancing scientific inquiry and for the development of innovative pharmaceutical formulations targeting health issues.

26) Glass:
Glass is utilized in the research for equipment, particularly in molds for forming the medicated sticks. Using glass ensures a sterile and non-reactive environment for the formulation process, which is crucial for maintaining the integrity and safety of the medicinal products developed for skin infections.

27) Cina:
In this context, 'China' refers to china dishes used during the heating process of preparing medicated sticks. The specific mention highlights the choice of materials in pharmaceutical preparations, clarifying their role in achieving desired formulation properties without affecting the component's stability or efficacy during production.

28) Food:
Food in this research context could refer to the nutrition offered to animal subjects during studies or to the general link between herbal medicines and diet. A well-balanced diet can contribute to overall health, enhancing the effectiveness of treatments derived from medicinal herbs like Abrus precatorius in combating infections.

29) Tree:
Tree may represent the natural habitat of Abrus precatorius, highlighting the importance of plant-derived medicines in traditional and modern pharmaceutics. Understanding a medicinal plant's ecological context is essential for its sustainable harvesting and for promoting the preservation of biodiversity in pharmaceutical research.

30) Hair:
Hair signifies the biological material that was shaved from the test area of animal subjects to facilitate accurate application of the medicated sticks during skin irritation studies. Ensuring a clean testing area is critical for reliable results, minimizing external factors that might influence the assessment of skin responses.

31) Pain:
Pain describes a physical symptom often associated with skin irritation or infections. The study aims to develop medicated sticks that alleviate such pain resulting from gynecological skin conditions, thus improving quality of life and adherence to treatment by providing effective relief from discomfort and associated symptoms.

32) Dish (Dis):
Dish refers to the china dish used for melting and mixing the ingredients during the preparation process of medicated sticks. Choosing a suitable dish is essential for maintaining hygiene and ensuring that the materials used do not react negatively, thereby safeguarding the integrity of the therapeutic formulation.