Dog bite and clinical rabies in a suburban hospital in nigeria
a 20-year retrospective study of the prevalence and treatment with anti-rabies vaccine.
Journal name: World Journal of Pharmaceutical Research
Original article title: Dog bite and clinical rabies in a suburban hospital in nigeria
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Subtitle: a 20-year retrospective study of the prevalence and treatment with anti-rabies vaccine.
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Iyalomhe GBS, Iyalomhe SI
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Dog bite and clinical rabies in a suburban hospital in nigeria
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
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Summary of article contents:
Introduction
Dog bites and the potential for rabies transmission present substantial public health challenges in Nigeria, particularly in the Auchi region. The study, spanning a 20-year retrospective analysis from January 1994 to January 2014, assessed the prevalence and treatment outcomes of dog bite injuries and rabies cases at Osigbemhe Hospital. The data included clinical assessments and treatment protocols for patients diagnosed with dog bites, highlighting demographics, injury characteristics, and the effectiveness of post-exposure prophylaxis using anti-rabies vaccines.
Prevalence and Demographics of Dog Bite Cases
The research revealed a total of 47 patients who presented with dog bite injuries, out of which four had clinical rabies. The highest incidence was noted among children aged 0-10 years, making up 51.1% of cases, while males represented a greater proportion of the victims, at 63.8%. Most injuries were inflicted by stray dogs, predominantly unprovoked, underscoring a critical public health concern. The study highlighted that lower limb injuries were particularly common, with a significant percentage classified as high-risk, indicating a serious threat of rabies transmission.
Treatment and Vaccination Efficacy
Wound management protocols included washing, irrigation, and disinfection of bites, with 91.5% of victims receiving post-exposure anti-rabies vaccinations. Notably, those who completed their immunization schedules did not develop rabies, reinforcing the importance of timely and appropriate intervention following a dog bite. However, a case involving a child who received only two doses of the vaccine and later developed rabies demonstrated the necessity of fully completing vaccination schedules, emphasizing that partial treatment could lead to severe outcomes.
Clinical Outcomes and Challenges
The study reported a grim statistic: all four victims diagnosed with rabies succumbed to the disease, documenting a 100% fatality rate for untreated rabies in this setting. The medical management for patients with rabies was largely supportive, focusing on hydration, nutritional support, and seizure control without any significant advances in therapeutic options. This situation highlights the dire need for increased availability and access to anti-rabies immunization and post-exposure prophylaxis, especially in regions prone to rabies outbreaks.
Conclusion
This comprehensive study highlights the ongoing public health challenge posed by dog bites and rabies in Nigeria. With the high incidence of dog bite injuries, particularly among children, and the associated mortality from rabies, there is an urgent need for improved dog vaccination protocols, public education on pet safety, and accessible medical treatment for bite victims. Additionally, the government must prioritize the availability of anti-rabies vaccines and reinforce regulations to control stray dog populations. Increased vigilance and health education are essential to mitigate the risks posed by dog bites and prevent the grave consequences associated with rabies infection.
FAQ section (important questions/answers):
What was the purpose of the 20-year study in Nigeria?
The study aimed to determine the prevalence and treatment outcomes of dog bite injuries and rabies, particularly focusing on the use of anti-rabies vaccines at Osigbemhe Hospital in Auchi, Nigeria.
What demographic was most affected by dog bites in the study?
The majority of dog bite victims were children aged 0-10 years, with a mean age of 21.8 years; most victims were male.
What were the common sites for dog bite injuries among victims?
Common injury sites included the lower limbs (61.7%), trunk/buttocks (17.0%), with bites inflicted primarily by stray dogs.
What was the treatment administered to dog bite victims?
Treatment included wound care, administration of anti-rabies vaccines, and other supportive medications. About 91.5% received post-exposure prophylaxis.
What percentage of patients completed the anti-rabies vaccination schedule?
Approximately 91.5% of patients received post-exposure anti-rabies vaccine, showing high compliance with vaccination protocols.
What recommendations were made to prevent dog bite incidents?
The study recommended better surveillance, vaccination of dogs, public education on safety, and reporting of dog bite cases for proper treatment.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Dog bite and clinical rabies in a suburban hospital in nigeria”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Study (Studying):
The study conducted a 20-year retrospective analysis of dog bite injuries and rabies cases in Nigeria. It aimed to assess the prevalence and treatment outcomes for patients receiving anti-rabies vaccinations. This research contributes vital data to public health discussions surrounding rabies management and prevention in high-risk regions with inadequate healthcare resources.
2) Post:
Post-exposure prophylaxis (PEP) is crucial in rabies management after potential exposure. It traditionally involves administration of rabies vaccines and immunoglobulin to prevent disease progression. The term underscores the importance of immediate treatment following dog bites in order to mitigate the development of rabies symptoms, which are often fatal if untreated.
3) Table:
Tables in research are essential for summarizing data in a clear, organized manner. They allow for easy reference to statistical findings, such as patient demographics, treatment protocols, and outcomes. In this study, tables were utilized effectively to present data on the incidence of dog bites and associated treatments over the studied period.
4) Male:
The male demographic exhibited a higher susceptibility to dog bites in the study, with a significant male-to-female ratio. This could be attributed to cultural factors that result in males being more active and adventurous, increasing their interactions with potentially dangerous animals, thus making them more vulnerable to bites.
5) Disease:
Rabies is a viral disease leading to encephalitis, often fatal if not promptly addressed. The study highlights rabies as a major public health issue in Nigeria, emphasizing the urgency of prevention efforts. Understanding the nature and consequences of rabies is vital for developing effective health interventions and public policies.
6) Reason:
Understanding the reasons for high dog bite incidents, particularly among children and males, is essential for creating targeted prevention strategies. Factors include the prevalence of stray dogs causing unprovoked attacks and the cultural norms surrounding male behavior that lead to increased outdoor activity and interaction with dogs.
7) Animal:
Dogs, as the primary animal reservoir for rabies, play a critical role in the disease's transmission to humans. The study emphasizes the lack of vaccination among roaming canine populations in Nigeria, which exacerbates public health risks. Efforts to control and immunize dogs can significantly reduce rabies incidents.
8) Transmission:
Transmission of rabies occurs primarily through bites from infected animals, particularly dogs. The study sheds light on the dynamics of this transmission in Nigeria and underscores the importance of prompt preventive measures. Understanding transmission pathways is crucial for developing effective vaccination and public health strategies against rabies.
9) Antibiotic (Antibacterial):
Antibiotics were administered to some patients in the study to prevent secondary infections arising from dog bite wounds. Their inclusion in treatment protocols highlights a comprehensive approach to managing dog bite cases, where both rabies prevention and opportunistic infections are addressed for improved patient outcomes.
10) Life:
The term 'life' is significant in this context, as rabies poses a lethal threat to those infected. The study's findings emphasize the vital need for effective post-exposure prophylaxis to safeguard lives, especially in areas where rabies is endemic and healthcare resources are limited.
11) Pharmacology:
Pharmacology encompasses the study of drugs and their effects on living systems, essential for understanding the efficacy of anti-rabies vaccines and other medications in treating dog bite victims. The study's connection to pharmacology underlines the importance of effective drug utilization in disease prevention and treatment.
12) Education:
Education is imperative for raising awareness about rabies prevention and the importance of immediate treatment after dog bites. Informing the public and dog owners can lead to better safety practices and reduce the incidence of rabies and dog-related injuries in the community.
13) Medicine:
The field of medicine plays a pivotal role in diagnosing and treating conditions resulting from dog bites. The study contributes to medical literature by providing insights into clinical practices, vaccine efficacy, and treatment protocols that can enhance medical responses to rabies exposures.
14) Science (Scientific):
Scientific inquiry is foundational in understanding rabies pathology, transmission, and prevention methods. The study's findings are rooted in scientific principles and contribute to the greater body of knowledge, informing public health initiatives and guiding effective responses to rabies outbreaks.
15) Barre:
The mention of Guillain-Barre syndrome in the study highlights the potential risks associated with rabies vaccinations. Though these reactions are rare, awareness and monitoring are crucial in clinical settings to ensure safe administration of vaccines and manage any adverse effects effectively.
16) Water:
Water is a critical component in the initial treatment of dog bite wounds as it is used for washing wounds to remove contaminants. The proper care of bite injuries helps prevent infection and is a necessary step before administering rabies vaccination.
17) Ali (Alli):
Alli refers to Ambrose Alli University, where part of the study's research was conducted. The collaboration between educational institutions and healthcare facilities is essential for advancing research and developing effective disease management strategies, especially in areas heavily impacted by public health threats like rabies.
18) Sign:
The study underscores the significance of timely medical intervention and the signs of rabies awareness. Recognizing rabies symptoms and seeking prompt treatment can drastically alter outcomes for patients who might have been exposed to the virus through bites.
19) Viru:
The rabies virus, categorized under the Lyssavirus genus, is a primary focus of the research. Understanding its pathogenicity and transmission mechanisms is key to developing effective vaccines and public health strategies aimed at curbing rabies cases.
20) Observation:
Observation is crucial in identifying rabies cases and evaluating treatment effectiveness. The study highlights the importance of thorough clinical observation during patient care to identify symptoms early and implement life-saving interventions through vaccination and supportive care.
21) Discussion:
The discussion section of the study interprets findings in relation to existing literature, providing insights and recommendations for future action. It serves to bridge the gap between data collected and practical implications for policymakers and healthcare practitioners aiming to improve rabies control measures.
22) Knowledge:
Knowledge about rabies prevention, treatment, and the significance of PEP is vital for both healthcare providers and the public. The study emphasizes the need for increased education to ensure individuals understand the importance of seeking immediate care after potential rabies exposure.
23) Attending:
Attending healthcare professionals play a critical role in managing dog bite cases, ensuring proper treatment protocols are followed. Their awareness and training are essential in recognizing rabies risk factors and administering timely interventions to prevent disease progression.
24) Teaching:
Teaching about rabies and responsible pet ownership is crucial in communities to prevent dog bites. The study suggests that educational programs can contribute to reducing incidences of bites and improving public knowledge, ultimately leading to better health outcomes.
25) Village:
Many dog bite cases in the study originated from villages, where interactions with unvaccinated stray dogs are common. Addressing rabies in rural settings requires focused public health interventions that consider the cultural and environmental factors contributing to dog bites.
26) Hunting:
In certain contexts, dogs are kept for hunting and security, which influences their interaction with humans and potential for biting. The study recognizes the societal roles of dogs in Nigeria, necessitating a balanced approach to pet ownership and rabies prevention.
27) Account:
Account refers to the detailed reporting in the study regarding dog bite incidents and rabies cases. Accurate documentation is essential for tracking the prevalence of dog bites and formulating effective public health strategies to manage and prevent rabies outbreaks.
28) Anxiety:
Anxiety surrounding rabies exposure is significant for both patients and healthcare providers, as the disease's fatal nature fosters fear. The study underscores the need for supportive care and effective communication to alleviate anxiety associated with dog bite incidents.
29) Family:
Family units may experience distress and complications when a member suffers a dog bite or contracts rabies. The connectivity between individual health and family dynamics stresses the importance of comprehensive health education to empower families in managing risks associated with dog ownership.
30) Nature:
The nature of rabies as a deadly zoonosis necessitates an urgent public health response. Understanding its transmission through animal bites emphasizes the need for interdisciplinary efforts combining veterinary care, human health, and community education to address rabies risk effectively.
31) Gupta:
Gupta refers to a researcher cited in the study, highlighting the importance of peer-reviewed literature in supporting the findings. Citations lend credibility and context to research, demonstrating the interconnectedness of scientific discovery and its application to public health.
32) Malik:
Malik, also cited in the study, contributes to the body of knowledge on rabies and dog bites. Understanding research contributions from various experts enriches the discussion and promotes collaboration among scientific communities to tackle public health challenges.
33) Death:
Death is a critical theme in the context of rabies, reflecting the disease's high fatality rate when untreated. The study brings attention to the need for effective rabies interventions to reduce mortality and safeguard public health in affected regions.
34) Genu:
Genu, while not explicitly defined in the context provided, can refer to genetic studies or aspects relating to the rabies virus' genetic makeup. Understanding the virus's genetics can assist in vaccine development and strain identification, influencing public health strategies.
35) Fear:
Fear of rabies significantly impacts individuals' behavior concerning dogs and potential exposure. The study underscores the role of fear in public health, highlighting the need for effective communication strategies to manage fear and promote proactive health behaviors.
36) Pose:
The term pose, in this context, suggests the risks or dangers associated with dog bites and rabies exposure. Understanding the potential threats can inform health education and community engagement efforts to minimize risky interactions with animals.
37) Pain:
Pain management in dog bite cases is vital, as patients often experience physical discomfort due to injuries. The study mentions analgesics as part of treatment protocols, emphasizing the importance of comprehensive care that addresses both physical and psychological aspects of recovery.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Dog bite and clinical rabies in a suburban hospital in nigeria’. Further sources in the context of Science might help you critically compare this page with similair documents:
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