Medicinal value of some edible leafy vegetables from bangladesh.

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Journal name: World Journal of Pharmaceutical Research
Original article title: Medicinal value of some edible leafy vegetables from bangladesh.
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Original source:

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Author:

Maksuda Khatun, Shariful haque, Md. Abul Hassan, Sheikh Nazrul Islam


World Journal of Pharmaceutical Research:

(An ISO 9001:2015 Certified International Journal)

Full text available for: Medicinal value of some edible leafy vegetables from bangladesh.

Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research

Copyright (license): WJPR: All rights reserved


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Summary of article contents:

Introduction

The study conducted by Maksuda et al. aimed to evaluate the antibacterial activity and anti-hyperglycemic effect of fourteen edible leafy vegetables from Bangladesh. The research addressed the increasing prevalence of type 2 diabetes globally and explored the potential of nutraceuticals—plant-derived food components with health benefits—as a preventative and therapeutic measure. With a focus on the antibacterial properties of these vegetables, the study aimed to provide scientific backing to traditional practices that used leafy vegetables in managing diabetes and bacterial infections.

Antihyperglycemic Effects of Leafy Vegetables

The anti-hyperglycemic effects of the fourteen tested vegetables were assessed through a series of experiments on 60 healthy rabbits, which underwent subcutaneous glucose tolerance tests after treatment with water, glipizide, or methanol extracts of leafy vegetables. Of these plants, ten displayed significant hypoglycemic effects, with serum glucose levels returning to normal within 28 days, and many achieving normal levels between 7 to 14 days of treatment. Seven of the vegetables exhibited stronger antidiabetic properties than the positive control, Dimerol. These included Chenopodium album, Hewittia sublobata, Hygrophila auriculata, Ipomoea batatus, Malva verticillata, Piper longum, and Portulaca quadrifida, indicating their potential as therapeutic agents in diabetes management.

Antibacterial Activity of Leafy Vegetables

Additionally, the study evaluated the antimicrobial efficacy of the methanol extracts of the leafy vegetables against various bacterial strains, both gram-positive and gram-negative. The antimicrobial activity was performed via the agar well diffusion method. The extracts demonstrated moderate to mild activity against several gram-positive bacteria, notably Leucas aspera, which exhibited a maximum inhibition zone of 17 mm against Sarcina lutea. Other species also displayed varying degrees of antibacterial activity, albeit none showed efficacy against gram-negative bacteria, likely due to their complex cell wall structures that limit penetration of the extracts.

Nutraceuticals and Herbal Medicine

The findings support the inclination towards utilizing nutraceuticals derived from edible plants, emphasizing their rich content of bioactive compounds, including antioxidants, vitamins, and minerals, that potentially confer health benefits. Leafy vegetables are highlighted as vital components of the human diet, contributing to overall health and the management of diseases. Secondary metabolites found in these plants are responsible for their therapeutic properties and play significant roles in cell growth and immune system support. This aspect underlines the importance of integrating traditional medicine with modern scientific research to explore safe and effective treatments for various ailments.

Conclusion

In conclusion, the study by Maksuda et al. underscores the medicinal potential of selected edible leafy vegetables from Bangladesh, particularly in the management of diabetes and bacterial infections. The significant antihyperglycemic and antibacterial properties demonstrated by several of the plants tested highlight their role as nutraceuticals. While the results indicate promising avenues for alternative therapies, further investigation with larger sample sizes and long-term studies is needed to validate these findings and explore possible clinical applications. The research illustrates the importance of preserving traditional knowledge through scientific validation, promoting the use of natural remedies in contemporary healthcare practices.

FAQ section (important questions/answers):

What was the aim of the study conducted by Maksuda et al.?

The study aimed to evaluate the antibacterial activity and anti-hyperglycemic effect of fourteen edible leafy vegetables from Bangladesh, particularly their potential benefits for diabetes management and microbial infections.

How was the anti-hyperglycemic effect evaluated in the study?

The anti-hyperglycemic effect was studied using 60 healthy rabbits that underwent weekly glucose tolerance tests after receiving various treatments, including methanol extracts of leafy vegetables.

Which leafy vegetables showed significant hypoglycemic activity in the study?

Seven species showed more antidiabetic properties than the positive control, including Chenopodium album, Hewittia sublobata, and Ipomoea batatus, among others.

What method was used to determine serum glucose levels in mice?

Serum glucose levels were determined using the glucose oxidase method, with blood samples collected from mice at various time intervals.

What were the results of the antibacterial activity testing?

The methanol extracts exhibited varying antibacterial activity, particularly against gram-positive bacteria, while most extracts showed little to no activity against gram-negative bacteria.

What are some medicinal properties of leafy vegetables according to the study?

Leafy vegetables are rich in antioxidants, phytochemicals, and essential nutrients, and possess anti-diabetic, anti-histaminic, anti-carcinogenic, and antimicrobial properties, making them important for health.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Medicinal value of some edible leafy vegetables from bangladesh.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Activity:
Activity refers to the biological effects exhibited by a substance, such as the hypoglycemic or antibacterial action demonstrated by the studied leafy vegetables. Findings of significant activity can lead researchers to understand how specific compounds can interact with biological systems and potentially lead to the development of therapeutic agents against diseases.

2) Antibiotic (Antibacterial):
Antibiotic signifies drugs used to treat bacterial infections. The study highlights the necessity of finding natural antidiabetic and antibacterial alternatives to synthetic antibiotics, particularly considering the global rise in antibiotic resistance, thus advocating for the exploration of nutraceuticals for effective treatment options.

3) Species:
Species refers to the distinct types of organisms in the study, specifically the fourteen edible leafy vegetables examined for their medicinal properties. Each species has unique biochemical compositions, contributing to the variability in their therapeutic effects, including the ability to lower blood glucose levels or exhibit antimicrobial activity.

4) Blood:
Blood is a vital fluid in the body responsible for transporting nutrients, oxygen, and hormones to cells, as well as removing waste products. The study monitored blood glucose levels in diabetic and non-diabetic mice, allowing researchers to assess the efficacy of the herbal extracts in managing diabetes.

5) Piper longum:
Piper longum, a species of medicinal plant included in the study, is known for its numerous health benefits, including potential anti-diabetic and antibacterial properties. Its inclusion highlights the diversity of the plants evaluated for their effects on blood glucose regulation and bacteria suppression in the research context.

6) Animal:
Animal refers to the subjects used in the experimental procedures, specifically white albino mice used for evaluating the hypoglycemic effects of the nutraceuticals. Utilizing animal models is essential for understanding how certain compounds behave in a living organism and their potential efficacy in treating human diseases.

7) Water:
Water is a critical solvent used throughout the study, notably for washing plant materials and facilitating the extraction process of active compounds from leafy vegetables. In biological research, water is essential for maintaining physiological conditions, hydration, and serving as a medium in many biochemical reactions.

8) Study (Studying):
Study denotes the comprehensive investigation undertaken to assess the antibacterial and anti-hyperglycemic properties of fourteen edible leafy vegetables. It represents a systematic approach to evaluate traditional knowledge about these plants and their relevance in contemporary medicine, potentially influencing future therapeutic applications.

9) Drug:
Drug refers to a substance used for medical treatment, prevention, or diagnosis. In this research, the comparison between the effects of herbal extracts and established drugs, like Gliclazide, emphasizes the potential of nutraceuticals in offering alternative or complementary treatment options for conditions like diabetes.

10) Science (Scientific):
Scientific pertains to the structured methodology applied in research. This study utilizes rigorous scientific techniques to validate the traditional uses of certain leafy vegetables, underscoring the importance of empirical evidence in ascertaining the health benefits of naturally sourced compounds.

11) Aureus:
Aureus refers to Staphylococcus aureus, a common gram-positive bacterium tested in the study for its susceptibility to the methanol extracts of various leafy vegetables. Understanding its interactions with natural compounds is critical for developing new antibacterial agents, especially in the face of rising antibiotic resistance.

12) Table:
Table refers to the organized data presentation used in the research to summarize key findings, including serum glucose levels and antibacterial activity. Tables are essential in scientific reporting as they facilitate the comparison and interpretation of results, enhancing clarity and understanding of the study's outcomes.

13) Rich (Rch):
Rich describes the abundance of bioactive compounds in leafy vegetables, which contribute to their medicinal properties. Being rich in phytochemicals, vitamins, and minerals emphasizes the potential health benefits of these plants, underlining their importance in both traditional remedies and modern nutritional practices.

14) Trigonella foenum-graecum:
Trigonella foenum-graecum, commonly known as fenugreek, is one of the fourteen leafy vegetables examined for its hypoglycemic effects. Its mention signifies the diverse range of plants contributing to the study, highlighting their specific roles in traditional medicine and potential therapeutic applications based on scientific evidence.

15) Disease:
Disease represents a pathological condition that disrupts normal bodily functions, such as diabetes, which was a focus of this study. Understanding how certain nutraceuticals affect disease processes is crucial for developing effective treatment options and promoting better health outcomes through diet.

16) Medium:
Medium refers to the environment or substance in which biological tests were conducted, particularly the agar media used for assessing antibacterial activity. Selecting appropriate media is essential for accurately evaluating the properties of plant extracts and ensuring reliable results in microbiological studies.

17) Diet:
Diet indicates the sum of food consumed by individuals, which can significantly influence health. The study correlates the intake of certain leafy vegetables within the diet to potential health benefits, especially in managing blood glucose levels and providing essential nutrients for overall well-being.

18) Wall:
Wall refers to the cell wall structure of bacteria, which influences their susceptibility to antibacterial agents. This study emphasizes the differences between gram-positive and gram-negative bacteria, providing insights into how the molecular structure of bacteria affects their interactions with natural compounds from plants.

19) Substance:
Substance refers to the specific chemical compounds present in the leafy vegetables that exhibit biological activity. Identifying and isolating these active substances is necessary for understanding their effects and developing potential therapeutic applications, gauging their relevance in health management and pharmacology.

20) Mineral:
Mineral indicates essential inorganic nutrients that play vital roles in various biological functions. The studied leafy vegetables are recognized for their mineral content, underscoring their nutritional value and potential contributions to health, particularly in supporting metabolic processes and improving bodily functions.

21) Powder:
Powder refers to the form of the leafy vegetable extracts after drying and grinding. This powdered form is essential for the extraction process and allows for easier handling and measurement in experiments, facilitating the assessment of the phytochemical content and biological activity.

22) Marma:
Marma is a term referring to an ethnic group in Bangladesh, highlighting the cultural aspect of the study. Acknowledging local vernacular names for the leafy vegetables enhances the understanding of their traditional uses and positions them within the context of heritage health practices.

23) Pata:
Pata means leaves in Bengali and pertains to the focus of the study on leafy vegetables. Recognizing the vernacular name helps bridge traditional knowledge with scientific inquiry, emphasizing the cultural significance of these plants in local diets and their potential health benefits.

24) Food:
Food broadly categorizes any substance consumed for nourishment. In this study, the edible leafy vegetables examined serve as a source of food, highlighting their importance in dietary considerations while also indicating their role as functional foods with potential health benefits.

25) Human body:
Human body represents the biological system affected by both dietary intake and medicinal treatments. The study is significant as it explores how certain plant extracts can influence biochemical processes within the human body, particularly in managing health conditions like diabetes.

26) Phytochemical:
Phytochemical refers to bioactive compounds found in plants that can impact human health. The leafy vegetables studied are rich in various phytochemicals, linking their traditional use to potential health-promoting properties and providing a basis for further research into their therapeutic benefits.

27) Accumulation (Accumulating, Accumulate):
Accumulated denotes the collection of bioactive substances in the plant’s tissues. The significance of accumulated phytochemicals relates to their potential health benefits and roles in therapeutic effects, which were systematically investigated in the study to support their traditional medicinal value.

28) Discussion:
Discussion reflects the analytical part of the study that interprets results, compares findings with existing literature, and provides insight into the implications of the research. It is critical for contextualizing study outcomes and guiding future inquiries into the health benefits of natural remedies.

29) Flavonoid:
Flavonoid is a type of phytochemical characterized by its antioxidant properties. The presence of flavonoids in the studied vegetables indicates their potential health benefits, such as reducing oxidative stress and contributing to overall wellness, linking diet with disease prevention.

30) Medicine:
Medicine entails the science and practice of diagnosing, treating, and preventing disease. The study explores how traditional leafy vegetables can serve medicinal purposes and pave the way for future pharmacological studies, contributing to the field of ethnopharmacology and the development of new therapeutic agents.

31) Bleeding:
Bleeding refers to the loss of blood, often requiring medical intervention. Understanding the properties of plants that may aid in preventing or addressing bleeding provides insights into traditional healing practices. It underscores the need for studying these plants to evaluate their effects on coagulation and wound healing.

32) Habitat:
Habitat signifies the natural environment where the studied leafy vegetables grow. Acknowledging specific habitats provides context regarding the ecological conditions that contribute to the growth and chemical profiles of these plants, indirectly influencing their medicinal properties and availability for use.

33) Family:
Family refers to the classification of plants that share common characteristics. It provides context for understanding the relationship between different plant species, facilitating the exploration of related compounds and their potential effects in the context of medicinal value and phytochemical content.

34) Cotton:
Cotton is a plant known primarily for its fibers; however, its association in this study may refer to materials used for laboratory procedures, including the preparation of experimental setups for extracting plant compounds. This highlights the often-overlooked aspects of the research environment and methodologies employed.

35) Botany:
Botany is the scientific study of plants, including their physiology, structure, and taxonomy. This field is integral to the research as it informs how the selected leafy vegetables are categorized, understood, and utilized within both traditional medicine and modern pharmaceutical applications.

36) House:
House in this context likely refers to the facility or establishment where animals were kept during the experiment. Proper housing conditions are crucial for experimental integrity and humane treatment of animals, ensuring that results are reliable and ethically obtained.

37) Pur:
Poor refers to the lack of effectiveness in certain compounds tested or the low activity of some plant extracts against specific bacterial strains. This indicates the need for further research to identify more potent sources or alternative methods for extracting active ingredients that could exhibit stronger biological actions.

Other Science Concepts:

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Discover the significance of concepts within the article: ‘Medicinal value of some edible leafy vegetables from bangladesh.’. Further sources in the context of Science might help you critically compare this page with similair documents:

Piper longum, Medicinal plant, Medicinal properties, Mortar and Pestle, Medical properties, Diabetes mellitus, Long-term treatment, Statistical analysis, Leafy vegetable, Medicinal value, Significant difference, Tribal communities, Descriptive Statistics, Antibacterial activity, Nutritional value, Bioactive substances, Preliminary phytochemical screening, Phytochemical screening, Anti-inflammatory activities, Oxidative stress, P Value, Antimicrobial activity, Zone of inhibition, In vitro antibacterial activity, Moringa oleifera, Anti Hyperglycemic effect, Animal experimentation, Secondary metabolite, Antibacterial properties, Antidiabetic properties, Antioxidant activities, Gram positive bacteria, Gram negative bacteria, Weight loss, Methanol extract, Tannin, Alloxan-induced diabetes, Serum glucose level, Whatman filter paper, Nutraceutical, Plant Extract, Natural source, Green leafy vegetables, In Vitro Antimicrobial Activity, Nutrient agar media, Antibiotic susceptibility testing, Experimental procedure, Aqueous seed extract, Experimental animal, Commercial kit, Hypoglycemic property, Glucose tolerance test, Epigallocatechin gallate, Folklore remedies, Diabetic mice, Fasting Blood Samples, Independent sample T-test, ELISA plate reader.

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