GC-MS phyto-chemical profiling of Abutilon hirtum leaf extracts.
Journal name: World Journal of Pharmaceutical Research
Original article title: Phyto-chemical profiling of abutilon hirtum (lam.) sweet. leaf extracts using gc-ms analysis
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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P. Vivekraj, Vijayan, A., Anandgideon, V. and Muthuselvam, D.
World Journal of Pharmaceutical Research:
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Full text available for: Phyto-chemical profiling of abutilon hirtum (lam.) sweet. leaf extracts using gc-ms analysis
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
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Summary of article contents:
Introduction
The research article focuses on the phytochemical profiling of Abutilon hirtum (Lam.) Sweet, a member of the Malvaceae family, known by the common name 'Vadathuthi.' This plant has been used in traditional medicine to treat various ailments, and the study employs gas chromatography coupled with mass spectrometry (GC-MS) to identify its phytochemical constituents. There is a growing interest in the therapeutic potential of plant-derived compounds compared to synthetic drugs, particularly concerning their safety and efficacy in human health.
Identification of Phytochemicals
The primary findings of the research reveal significant phytochemical properties in the ethanolic leaf extract of Abutilon hirtum. The GC-MS analysis identified various compounds, including phenols, flavonoids, tannins, terpenoids, and phytosterols. This study is notable as it reports these specific phytochemicals in A. hirtum for the first time. The presence of these compounds indicates the potential for A. hirtum to contribute to the development of new therapeutic agents, highlighting the plant's relevance in medicinal applications.
Traditional Uses and Pharmacological Potential
Abutilon hirtum has a rich heritage of traditional medicinal applications, particularly in India, where its leaves are used for treating ailments such as inflammation, ulcers, and urinary disorders. Different cultures utilize various parts of the plant for culinary and health purposes, reinforcing its importance in ethnomedicine. The study emphasizes the plant's potential hepatoprotective properties, as well as its nutritional benefits, underlining the need for further research into its bioactive compounds and therapeutic effects.
Methodology and GC-MS Analysis
The methodology involved collecting and preparing the A. hirtum plant samples, followed by extraction with ethanol. Using a Soxhlet extractor, the efficiency of phytochemical extraction was maximized. The use of the Agilent-7890A GC instrument coupled with MS-5975 allowed for a sophisticated analysis of compound identification. The results, presented in chromatograms and tables, provide a detailed overview of the phytocomponents, their retention times, molecular formulas, and their concentrations.
Conclusion
The study concludes that Abutilon hirtum exhibits a rich array of phytochemicals that are valuable for medicinal and traditional practices. The significant presence of compounds identified through the GC-MS analysis suggests a promising avenue for future research, particularly concerning microbial activity and potential therapeutic uses. Overall, the findings advocate for the extensive exploration of A. hirtum as a source of natural remedies, reinforcing its significance in the context of herbal medicine and plant biotechnology.
FAQ section (important questions/answers):
What is Abutilon hirtum and its traditional uses?
Abutilon hirtum, known as Vadathuthi, is a plant used in traditional medicine for treating various ailments such as kidney issues, ulcers, and bladder inflammations. Its leaves have demulcent, diuretic, and hepatoprotective properties.
What method was used to analyze the phytochemicals in the study?
The study utilized gas chromatography coupled with mass spectrometry (GC-MS) to identify and profile phytochemicals present in the ethanolic leaf extract of Abutilon hirtum.
What phytochemicals were identified in the ethanolic leaf extract?
The analysis revealed the presence of phytochemicals such as terpenoids, glycosides, alkaloids, phenols, flavonoids, tannins, and phytosterols, which are significant for their medicinal properties.
Where was Abutilon hirtum collected for the study?
Abutilon hirtum specimens were collected from Tiruchirappalli, Tamilnadu, in southern India, and were authenticated by the Botanical Survey of India.
What are some specific phytocompounds found in the study's results?
Notable phytocompounds identified include Methyl salicylate, 9,12,15-Octadecatrienoic acid, and Phytol, each having potential pharmaceutical applications.
What conclusion was drawn regarding the use of A. hirtum?
The study concluded that the ethanolic extract of A. hirtum has significant medicinal value, indicating it could aid in treating various human ailments.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “GC-MS phyto-chemical profiling of Abutilon hirtum leaf extracts.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) India:
India is a country located in South Asia known for its rich biodiversity and traditional medicinal practices. The use of indigenous plants in healing and their cultural significance form an essential part of its healthcare system. Many plants, including *Abutilon hirtum*, are part of India's extensive herbal knowledge.
2) Phytochemical:
Phytochemicals are bioactive compounds produced by plants that offer health benefits and provide protective effects against various diseases. They play a crucial role in the medicinal value of plants, assisting the body in healing processes. Understanding phytochemicals enhances the knowledge of traditional medicine and its applications.
3) Disease:
Disease refers to any condition that disrupts the normal functioning of the body, often leading to various symptoms and impairing health. Plants like *Abutilon hirtum* have historical significance in treating diseases, showcasing their potential as natural alternatives to synthetic medications in modern medicine.
4) Medicine:
Medicine encompasses the science and practice of diagnosing, treating, and preventing ailments. Traditional systems, including herbal medicine, rely on plants for their therapeutic properties. Understanding the medicinal usage of plants like *Abutilon hirtum* is vital for integrating these natural therapies into contemporary healthcare practices.
5) Flavonoid:
Flavonoids are a group of phytonutrients recognized for their antioxidant properties and potential health benefits. They are found in various plants and contribute to their medicinal effects. The identification of flavonoids in *Abutilon hirtum* enhances its credibility as a source of natural therapeutic agents.
6) Activity:
Activity refers to the measurable effects of phytochemicals, including their biological and pharmacological functions. Investigating the activity of plant extracts can provide insights into their potential applications for health benefits, particularly in the development of herbal medications and understanding traditional healing practices.
7) Family:
Family, in botanical terms, categorizes plants into groups based on shared characteristics. *Abutilon hirtum* belongs to the Malvaceae family, which informs researchers about its potential uses, relative characteristics, and phytochemical composition. Understanding plant families aids in identifying properties of related species.
8) Botany:
Botany is the scientific study of plants, exploring their structure, function, growth, and taxonomy. Knowledge in botany is essential for understanding medicinal plants, facilitating the exploration of their potential benefits in medicine, agriculture, and ecology. Research in botany supports the integration of traditional and modern practices.
9) Ulcer:
An ulcer is a sore that develops on the lining of the stomach, intestines, or other body surfaces. The traditional use of plants like *Abutilon hirtum* for treating ulcers highlights the significance of herbal remedies in managing digestive health and promoting healing naturally.
10) Table:
In scientific research, a table presents data clearly and succinctly. Tables summarize complex information, such as the results of phytochemical analyses, allowing for easy interpretation and comparison. In this study, a table displays the identified compounds in the ethanolic extract of *Abutilon hirtum*.
11) Drug:
A drug is a substance used to diagnose, cure, treat, or prevent disease. The exploration of plant-derived compounds leads to the development of natural drugs, as seen in the investigation of *Abutilon hirtum*. This emphasizes the importance of traditional medicine in modern pharmacology.
12) Inflammation:
Inflammation is the body's response to injury or infection, often causing redness, swelling, and pain. Certain phytochemicals, such as those found in *Abutilon hirtum*, are known for their anti-inflammatory properties, which can help in managing and alleviating inflammatory conditions, reflecting their therapeutic potential.
13) Discussion:
Discussion is a crucial part of scientific research, where findings are interpreted and their implications are analyzed. It allows researchers to contextualize results, explore their significance, and suggest potential future investigations. In the study, discussion centers on the implications of the identified phytochemicals.
14) Science (Scientific):
Scientific pertains to systematic knowledge derived from the study through observation and experimentation. The scientific approach is essential in validating traditional practices, such as the use of herbal medicine. Research on *Abutilon hirtum* employs scientific methods to understand its phytochemical profiles and potential health benefits.
15) Knowledge:
Knowledge refers to the understanding gained from research and experience. In the context of medicinal plants, knowledge encompasses the identification, use, and effects of phytochemicals, promoting informed decisions in health care. Expanding knowledge on *Abutilon hirtum* can enhance therapeutic applications and traditional practices.
16) Substance:
Substance refers to a particular kind of matter with uniform properties. In the study, the focus is on plant substances that possess active phytochemicals, contributing to their medicinal value. Understanding the nature of these substances is critical in developing effective herbal treatments.
17) Tamilnadu (Tamil-nadu):
Tamilnadu is a state in southern India known for its rich biodiversity and traditional medicine. Many medicinal plants, including *Abutilon hirtum*, are native to this region. The cultural heritage of Tamilnadu plays an integral role in the utilization of these plants for therapeutic purposes.
18) Study (Studying):
Study pertains to the investigation and analysis of particular topics within the scientific field. The study of *Abutilon hirtum* focuses on identifying its phytochemical components and understanding their medicinal potential. This contributes valuable information to both research and traditional medicinal practices.
19) Species:
Species is the basic unit of biological classification, referring to a group of organisms capable of interbreeding. *Abutilon hirtum* represents one species within the vast diversity of the Malvaceae family. Understanding various species helps in exploring their unique properties and applications.
20) Powder:
Powder refers to a finely ground substance, often used for extraction in phytochemical studies. The leaves of *Abutilon hirtum* were ground into powder to prepare extracts for analysis. The method of preparation can significantly impact the extraction efficiency and subsequent analysis results.
21) Indian:
Indian signifies anything related to India, especially its culture, traditions, and natural resources. The medicinal use of plants, including *Abutilon hirtum*, is rooted in Indian culture and highlights the significance of traditional knowledge in modern medicinal practices and the ongoing exploration of herbal treatments.
22) Water:
Water is a universal solvent and plays a vital role in various biological processes. In the context of herbal remedies, water is often used to prepare extracts, showcasing the importance of understanding extraction methods to maximize the benefits of medicinal plants like *Abutilon hirtum*.
23) Camel:
Camel refers to a domesticated animal commonly found in arid regions. In the context of *Abutilon hirtum*, it highlights the plant's use as forage for animals, emphasizing its ecological role and nutritional value, thereby illustrating the diverse applications and importance of plants in both animal and human health.
24) Genu:
Genu in botanical terms refers to the taxonomic classification of plants into various genera. Understanding the genus of a plant informs about its ecological relationships and characteristics. *Abutilon hirtum* represents a specific genus within the Malvaceae family, aiding in the study of its properties.
25) Rice (Rce):
Rice, a staple food crop, signifies the cultural importance of agriculture in regions like Tamilnadu. The mention of rice in conjunction with *Abutilon hirtum* highlights traditional practices in which the plant is used in preparations, demonstrating the interconnections between local agriculture, culture, and herbal medicine.
26) Rich (Rch):
Rich describes the abundance of resources or qualities associated with a subject. Referring to the rich heritage of traditional medicine implies the extensive knowledge and practice surrounding medicinal plants, such as *Abutilon hirtum*, and their contributions to health and healing across cultures.
27) Pain:
Pain is a significant symptom signaling discomfort or distress in the body. The use of plants like *Abutilon hirtum* to ease pain illustrates the importance of traditional remedies in managing symptoms. It emphasizes the necessity of studying plant-based treatments to alleviate suffering effectively.
Other Science Concepts:
Discover the significance of concepts within the article: ‘GC-MS phyto-chemical profiling of Abutilon hirtum leaf extracts.’. Further sources in the context of Science might help you critically compare this page with similair documents:
Medicinal plant, Phytochemical, Traditional medicine, Complementary and alternative medicine, Phytochemical screening, Phytochemical analysis, Hepatoprotective activity, Traditional System of Medicine, Molecular weight, Secondary metabolite, Ethanolic extract, Retention time, Phytochemical studies, Methanolic extract, Nutritional analysis, Extraction method, Phytochemical characterization, Plant origin drugs, Qualitative phytochemical screening, Human ailments, FTIR, GC-MS analysis, World Journal of Pharmaceutical Research, Ethanolic leaf extract, Phytochemical profiling, Poultice application, Plant product, Solvent extract, UV-Vis.