A short review on callus studies of biophytum sensitivum linn.
Journal name: World Journal of Pharmaceutical Research
Original article title: A short review on callus studies of biophytum sensitivum linn.
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Sirigiri Chandra Kala and Kokkanti Mallikarjuna
World Journal of Pharmaceutical Research:
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Full text available for: A short review on callus studies of biophytum sensitivum linn.
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
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Summary of article contents:
Introduction
Medicinal plants have been utilized for millennia as traditional remedies for a wide array of human ailments, and they continue to play a crucial role in healthcare, particularly in developing countries where up to 80% of the population relies on traditional medicine. This reliance highlights the importance of exploring the natural flora for the commercial production of drugs, as they are a rich source of biologically active compounds that serve as the foundation for new pharmaceuticals. This review focuses on the callus studies of Biophytum sensitivum, a medicinal plant known for its various therapeutic properties.
Phytochemical Potential of Callus Extracts
Biophytum sensitivum, commonly referred to as the life plant, has demonstrated significant medicinal properties, including its effects on inflammatory diseases and diabetes treatment. The study of callus cultures derived from this plant provides an opportunity to analyze and isolate secondary metabolites that hold potential pharmaceutical value. Callus tissue, cultivated through plant tissue culture techniques, exhibits varying textures based on factors such as explant type and cultural conditions. By optimizing these conditions, researchers discovered that specific growth regulators enhanced callus formation, thereby increasing the potential yield of secondary metabolites for further pharmacological studies.
Antimicrobial Activity
The antimicrobial properties of Biophytum sensitivum have also been investigated through its callus extracts. Antimicrobial agents derived from medicinal plants have historically played a significant role in combating infectious diseases. The leaf callus extracts of Biophytum sensitivum were tested against various bacterial and fungal species, revealing that the extracts contain phytochemicals capable of inhibiting microbial growth. Notably, the extracts demonstrated inhibition against several strains of Gram-positive and Gram-negative bacteria, showcasing their potential application in the development of new antimicrobial agents.
Pharmacological Evaluation
Beyond antimicrobial activity, the pharmacological potential of Biophytum sensitivum extends to its effects on enzyme inhibition, which is critical for drug development. The methanol extracts of the plant’s callus exhibited inhibitory effects on several enzymes, including α-glucosidase and acetyl cholinesterase, contributing to its therapeutic profile. However, the study also noted a relatively low potency in enzyme inhibition and antioxidant activity, likely attributed to the low concentrations of phenolic compounds present in the extracts. This finding emphasizes the need for further investigation into enhancing the antioxidant properties and therapeutic effectiveness through concentrated extraction.
Conclusion
In conclusion, the callus of Biophytum sensitivum presents an invaluable resource for pharmaceutical research, offering promising avenues for the isolation of therapeutic compounds and evaluation of their antimicrobial and pharmacological potential. The insights gained from studying this plant's callus extracts not only reinforce its medicinal significance but also pave the way for future research aimed at isolating active principles and conducting comprehensive pharmacological assessments. Acknowledgments were given to the funding received from the University Grants Commission for supporting further exploration of this noteworthy species.
FAQ section (important questions/answers):
What is the common name and family of Biophytum sensitivum?
Biophytum sensitivum is commonly known as life plant, little tree plant, or sensitive plant. It belongs to the Oxalidaceae family and is recognized for its medicinal properties.
What are the primary medicinal properties of Biophytum sensitivum?
Biophytum sensitivum exhibits a wide range of medicinal properties, including anti-inflammatory effects, antiseptic qualities, and the ability to manage diabetes, along with immunomodulatory and antioxidant activities.
How are callus cultures beneficial for Biophytum sensitivum?
Callus cultures allow for the production of large quantities of herbal material and the development of economically valuable secondary metabolites, aiding in the study and application of the plant's medicinal properties.
What phytochemicals are found in callus extracts of Biophytum sensitivum?
Phytochemical analyses reveal the presence of flavonoids, terpenoids, saponins, quinones, and phenols in the callus extracts of Biophytum sensitivum, which contribute to its medicinal effectiveness.
How effective are callus extracts against microbial growth?
The antimicrobial screening showed that callus extracts of Biophytum sensitivum can inhibit the growth of various bacteria and fungi, highlighting their potential for developing new antimicrobial agents.
What are the key findings from pharmacological studies on callus extracts?
Pharmacological studies indicate that methanol callus extracts of Biophytum sensitivum exhibit inhibition of various enzyme activities and demonstrate notable cytotoxic activity, emphasizing their therapeutic potential.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “A short review on callus studies of biophytum sensitivum linn.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Drug:
Drug refers to a substance used for medical treatment to alleviate symptoms, manage diseases, or enhance bodily functions. In the context of medicinal plants like Biophytum sensitivum, the focus on drug development stems from their biological activities and phytochemical constituents that can lead to effective pharmaceutical products. These naturally derived drugs are essential in modern healthcare systems.
2) Activity:
Activity pertains to the efficacy of a substance, often measured in terms of its biological effects, such as antimicrobial or anti-inflammatory properties. When discussing callus extracts of Biophytum sensitivum, the activity indicates the potential healing properties that can be leveraged to develop new treatments and improve health outcomes.
3) Kala:
Kala is a surname associated with the first author, Dr. Sirigiri Chandra Kala, indicating her contributions to the study of Biophytum sensitivum's medicinal properties. The name reflects her identity and dedication to advancing knowledge in botany and pharmacognosy through rigorous research and scholarly activities in the field.
4) Pharmacological:
Pharmacological relates to the effects of drugs and their mechanisms within biological systems. This term is crucial for understanding how extracts from Biophytum sensitivum interact with cellular processes, including enzyme inhibition and antioxidant activity, which may lead to their therapeutic applications in treating various conditions.
5) Phytochemical:
Phytochemical refers to the bioactive compounds extracted from plants that contribute to their medicinal properties. The identification of phytochemicals in Biophytum sensitivum's callus extracts underscores the importance of these substances in developing new pharmaceutical drugs and their role in traditional medicine.
6) Chandra:
Chandra represents the first name of one of the authors, Dr. Sirigiri Chandra Kala, emphasizing her personal contribution to the research on Biophytum sensitivum. It reflects her academic identity and connection to the body of work focusing on exploring plant-based therapies.
7) Disease:
Disease signifies a pathological condition that impairs normal bodily functions, often targeted by medicinal treatments. The study of Biophytum sensitivum focuses on its therapeutic potential against various diseases, highlighting the importance of natural products in developing remedies for health issues prevalent in society.
8) Species:
Species refers to a specific group of organisms that can interbreed. In this context, Biophytum sensitivum is acknowledged as a valuable species within the Oxalidaceae family, underscoring its unique characteristics, ecological role, and medicinal applications, which can be further researched for drug discovery.
9) Nagarjuna:
Nagarjuna relates to Acharya Nagarjuna University, where the research was conducted. This name identifies the institution dedicated to higher education and research, instrumental in fostering studies in botany and microbiology, particularly concerning the medicinal properties of local flora.
10) Sirigiri:
Sirigiri is the first name of Dr. Sirigiri Chandra Kala, a significant contributor to the research discussed in the article. Her work reflects her expertise in the investigation of medicinal plants and highlights her contribution to a field that bridges traditional knowledge and modern science.
11) Medicine:
Medicine encapsulates the science and practice of diagnosing, treating, and preventing diseases. The exploration of Biophytum sensitivum's extracts signifies the ongoing efforts to integrate natural remedies into medical practice, thereby expanding treatment options and providing alternatives to synthetic pharmaceuticals.
12) Life:
Life denotes the biological phenomenon that encompasses growth, reproduction, and functional activity. The study of Biophytum sensitivum emphasizes its role as a 'life plant,' highlighting its traditional uses and importance in providing remedies that promote well-being and health among various populations.
13) Developing:
Developing pertains to the process of growth or advancement, particularly in relation to cultivating new pharmaceutical treatments. This term emphasizes the potential of research on Biophytum sensitivum to lead to significant advancements in drug development that can benefit healthcare in developing regions and beyond.
14) Andhra (Amdhra):
Andhra points to Andhra Pradesh, the Indian state where the study took place. This geographical context is essential for understanding the local flora's significance, traditional practices, and the cultural background that influences the use of medicinal plants like Biophytum sensitivum.
15) Medium:
Medium in this context refers to the growth environment used in tissue culture for callus generation. The appropriate medium, supplemented with growth regulators, is critical for optimizing the proliferation of plant tissues and for enhancing the yield of useful phytochemicals for pharmaceutical applications.
16) Botany:
Botany is the scientific study of plants, encompassing their physiology, structure, genetics, and ecology. The research conducted on Biophytum sensitivum contributes to the larger field of botany by providing insights into plant-based medicines and supporting the classification and understanding of plant species.
17) India:
India denotes the country where the research was undertaken, rich in biodiversity and traditional medicinal knowledge. The relevance of studying local plants like Biophytum sensitivum lies in their historical use and potential modern applications in healthcare and pharmacology.
18) Study (Studying):
Studying describes the process of investigating and analyzing specific phenomena. In this article, the act of studying Biophytum sensitivum's extracts emphasizes the importance of research in uncovering the medicinal properties and pharmacological potentials of plants.
19) New Delhi:
New Delhi is the capital city of India, representing a center for policy-making and governance, including regulations related to drug development and research. The mention of New Delhi emphasizes the institutional and governmental support for scientific research and education in the country.
20) Mallikarjuna (Mallika-arjuna):
Mallikarjuna refers to Dr. Kokkanti Mallikarjuna, the co-author of the study. His collaboration highlights the collaborative nature of research in botanical studies, showcasing the integration of different areas of expertise to advance the understanding of medicinal plants.
21) Lakshmana (Laksmana):
Lakshmana relates to a name associated with the traditional uses of Biophytum sensitivum in different cultures, particularly in Hindi-speaking regions. Understanding culturally relevant names enriches the knowledge of how the plant is perceived and utilized in various communities.
22) Substance:
Substance refers to any material with defined properties. In this context, it emphasizes the chemical compounds derived from Biophytum sensitivum that are studied for their medicinal effects, supporting the exploration of natural products in drug development and therapeutic applications.
23) Evolution:
Evolution in this context signifies the development and sophistication of new drug formulations based on findings from studies like those on Biophytum sensitivum. The concept highlights the need for continuous research and adaptation of traditional remedies to modern medical practices.
24) Flavonoid:
Flavonoid denotes a class of phytochemicals known for their antioxidant and anti-inflammatory properties. The presence of flavonoids in Biophytum sensitivum's extracts suggests potential health benefits, reinforcing the importance of these compounds in natural product research and their role in modern medicine.
25) Lajalu:
Lajalu is a name for Biophytum sensitivum in Hindi, reflecting its cultural significance and traditional uses in Indian medicine. Recognizing local names enhances the understanding of the plant's role in indigenous healing practices and its acceptance within communities.
26) Pushpa (Puspa):
Pushpa translates to 'flower' in Hindi, highlighting the floral characteristics of Biophytum sensitivum. This term connects to the plant's aesthetic and biological aspects, emphasizing its significance in both ecological and traditional medicinal contexts.
27) Family:
Family refers to the broader taxonomic classification grouping related organisms. Biophytum sensitivum belongs to the Oxalidaceae family, which underscores the botanical relationships among different species and informs studies on its biological activities and potential medicinal uses.
28) Reason:
Reason here emphasizes the justification for conducting research on Biophytum sensitivum. Validating the beneficial effects of its extracts serves the purpose of linking traditional knowledge with scientific inquiry to address health challenges and explore new therapeutic avenues.
29) Delhi:
Delhi, as a capital city, is a significant hub for research, policy-making, and educational initiatives related to health and medicine. Its mention signifies the importance of institutional support for advancing studies on natural products and their applications in modern medicine.
30) Death:
Death relates to the ultimate outcome of untreated diseases that medicinal plants aim to combat. The consideration of plant-based treatments signifies an approach to decreasing morbidity and mortality rates, especially in developing regions where access to modern healthcare may be limited.
31) Jala:
Jala refers to water in various Indian languages, possibly alluding to the plant's habitat or cultivation needs. Understanding such terms helps contextualize the environmental factors affecting Biophytum sensitivum's growth and its uses in traditional medicine.
32) Tree:
Tree refers to the stature of the Biophytum sensitivum, which resembles a miniature palm. This term highlights the morphological features of the plant, emphasizing its uniqueness in appearance and its place within ecological and botanical classifications.
Other Science Concepts:
Discover the significance of concepts within the article: ‘A short review on callus studies of biophytum sensitivum linn.’. Further sources in the context of Science might help you critically compare this page with similair documents:
Biophytum sensitivum, Medicinal plant, Natural product, Traditional medicine, Allopathic medicine, Bacterial infection, Traditional treatment, Cultural environment, Anti-inflammatory activity, Antioxidant activity, Pharmacological evaluation, Pharmacological activities, Phytochemical analysis, Oxidative stress, In vitro, Antimicrobial agent, Antifungal activity, Secondary metabolite, Cytotoxic activity, Pharmacological studies, Gram positive bacteria, Gram negative bacteria, Antiseptic properties, Antioxidant potential, Hypoglycemic effect, In vitro screening, Crude drug identification, Antimicrobial screening, Callus extracts, Cell mediated immune response, Phytochemical constituent.
Concepts being referred in other categories, contexts and sources.