GC-MS analysis of bioactive compounds in Actiniopteris radiata.

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Journal name: World Journal of Pharmaceutical Research
Original article title: Gc-ms analysis of bioactive components of an important medicinal fern actiniopteris radiata (swartz) link.
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Author:

Manonmani R. and Catharin Sara S.


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World Journal of Pharmaceutical Research:

(An ISO 9001:2015 Certified International Journal)

Full text available for: Gc-ms analysis of bioactive components of an important medicinal fern actiniopteris radiata (swartz) link.

Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research

Copyright (license): WJPR: All rights reserved


Summary of article contents:

Introduction

The study conducted by Manonmani et al. (2015) focuses on the phytochemical components of the medicinal fern Actiniopteris radiata (Pteridaceae) through Gas Chromatography-Mass Spectrometry (GC-MS) analysis. This research highlights the significance of phytochemical constituents in the medicinal activities of plant species, with a specific emphasis on the bioactive components present in the ethanolic extract of the fern. The identification of these components is crucial, as they may lead to novel drug discovery and validate the traditional medicinal uses of the plant.

Bioactive Compounds Identified

The GC-MS analysis revealed five key bioactive compounds in the ethanolic extract of A. radiata. These compounds include Hexadecanoic acid, ethyl ester (20.40%), 9,12-Octadecadienoic acid, methyl ester, (E,E)- (10.91%), (E)-9-Octadecenoic acid, ethyl ester (63.59%), Docosanoic acid, ethyl ester (4.26%), and Heptadecanoic acid, heptadecyl ester (0.84%). Each compound possesses various health benefits, reflecting the plant's therapeutic potential. The most abundant compound, (E)-9-Octadecenoic acid ethyl ester, stands out with a concentration of 63.59% and is associated with notable anti-inflammatory properties, among others, which highlights the importance of this bioactive component.

Traditional Medicinal Uses

Actiniopteris radiata has a longstanding history as a traditional remedy for various ailments, emphasizing its significance in folklore medicine. The plant is reputed to possess a range of medicinal properties, including antibacterial, anti-inflammatory, and antioxidant effects, making it valuable for treating conditions such as diarrhea, dysentery, leprosy, and fever. The research reinforces these traditional claims by documenting the presence of bioactive compounds that can be linked to the pharmacological activities of the plant, supporting its continued use in herbal medicine.

Future Directions in Pharmacological Research

The research suggests that further investigation is warranted to isolate individual phytochemical compounds from A. radiata and evaluate their biological activity and toxicity profiles. Such studies could yield deeper insights into the plant's medicinal properties and potentially lead to the development of new therapeutic agents. The documented presence of various bioactive compounds highlights the fern's importance as a candidate for pharmaceutical research and development, with the potential to address various health concerns through novel drug formulations.

Conclusion

The findings from this study underscore the significance of Actiniopteris radiata as a source of bioactive compounds with various medicinal applications. The identification of five key phytochemicals through GC-MS analysis affirms the plant's traditional usage and opens avenues for further research into its pharmacological benefits. With the potential for isolating and studying these compounds further, A. radiata may play an essential role in future medicinal discoveries, confirming its value in both traditional and modern medicine.

FAQ section (important questions/answers):

What is the main focus of the study on Actiniopteris radiata?

The study analyzes the bioactive components of Actiniopteris radiata using GC-MS, identifying five significant phytochemical compounds responsible for its medicinal properties.

Which five bioactive compounds were identified from the plant extract?

The identified compounds include Hexadecanoic acid, ethyl ester, Octadecadienoic acid, ethyl ester, (E)-9-Octadecenoic acid, Docosanoic acid, ethyl ester, and Heptadecanoic acid.

What traditional medicinal uses does Actiniopteris radiata have?

Actiniopteris radiata is used for various ailments including skin diseases, diabetes, fever, and as a remedy for leprosy and dysentery.

How was the ethanolic extract prepared for GC-MS analysis?

The powdered whole plant was soaked in absolute alcohol overnight, filtered, and concentrated to yield an extract containing both polar and non-polar phytocomponents.

Why are bioactive compounds from this fern important?

Bioactive compounds exhibit various pharmacological activities, suggesting potential for therapeutic applications and verifying traditional uses in medicine.

What further research is suggested based on the findings?

The study recommends isolating individual phytochemical constituents for further biological activity testing and assessing toxicity profiles to establish pharmacological safety.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “GC-MS analysis of bioactive compounds in Actiniopteris radiata.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Phytochemical:
Phytochemicals are bioactive compounds produced by plants, contributing to the medicinal properties and therapeutic qualities of traditional medicines. They are often the target of studies aimed at understanding plant-based remedies, including their chemical structure, biological activity, and potential health benefits, making them crucial in the pharmaceutical field.

2) Activity:
In the context of medicinal plants, activity refers to the pharmacological effects exhibited by various bioactive compounds. This can include actions such as anti-inflammatory, antibacterial, or antioxidant effects, which are essential in determining the therapeutic potential and clinical applications of plant-based remedies.

3) Tamil:
Tamil refers to both the Dravidian language spoken predominantly in Tamil Nadu, India, and the cultural heritage of the Tamil people. It plays a significant role in traditional medicine systems, including folk knowledge about local plants and their medicinal properties, contributing to the understanding of phytotherapy.

4) Tamilnadu (Tamil-nadu):
Tamil Nadu is a state in southern India renowned for its rich biodiversity, traditional medicine practices, and extensive flora. Home to numerous medicinal plants, it serves as a significant source for ethnic and herbal medicine, where local communities have utilized plant species for healing for centuries.

5) India:
India is a country with a vast and diverse ecosystem, making it one of the richest regions for medicinal plants and traditional medicine systems such as Ayurveda. The historical use of plants in Indian culture highlights their importance in herbal remedies and the ongoing research in phytochemistry.

6) Nadu:
Nadu, as part of the term Tamil Nadu, signifies the land or region, emphasizing geographical and cultural identity. It reflects the rich heritage and the traditional knowledge inherent in local practices of utilizing regional flora for medicinal purposes.

7) Cancer:
Cancer is a significant global health issue, and research into phytochemicals from plants like Actiniopteris radiata aims to identify compounds with potential anticancer properties. Understanding the chemical constituents that exhibit this activity is essential for developing new cancer prevention and treatment strategies.

8) Drug:
In this context, a drug refers to a substance used for treating, curing, preventing, or diagnosing illness. The identification of bioactive phytochemicals through studies like GC-MS analysis paves the way for the development of novel drugs derived from natural plant sources.

9) Pharmacological:
Pharmacological studies evaluate the effects of various compounds on biological systems, guiding their use in treating diseases. The pharmacological activity of identified phytochemicals helps to elucidate their potential benefits and therapeutic uses within traditional medicine frameworks.

10) Medicine:
Medicine is the science and practice of diagnosing, treating, and preventing illness, often utilizing natural substances. The exploration of plant-based extracts for their medicinal properties is a critical aspect of health care, particularly in regions with traditional practices.

11) Trichy:
Trichy, or Tiruchirappalli, is a city in Tamil Nadu, India, known for its educational and research institutions. It provides a backdrop for studying local flora and contributes to the scientific exploration of medicinal plants through various institutions focused on botany and pharmacognosy.

12) Nature:
Nature encompasses the physical world, including living organisms and ecosystems. The study of natural products, including phytochemicals from plants, emphasizes the importance of nature in providing medicinal resources and biological diversity that supports ecological and human health.

13) Botany:
Botany is the scientific study of plants, their structure, properties, and biochemical processes. It is essential for understanding the medicinal potential of plant species, including their phytochemical constituents and their applications in traditional and modern medicine.

14) Thanjavur:
Thanjavur is a city in Tamil Nadu known for its cultural heritage and agricultural practices. It is significant in the study of medicinal plants due to its biodiversity, providing access to various species with traditional uses in local medicine.

15) Disease:
A disease is a condition that impairs normal bodily functions. Studying phytochemicals from plants like Actiniopteris radiata helps to identify natural remedies that can offer new treatment options for diseases, including those prevalent in traditional medicine.

16) Species:
Species refer to distinct biological classifications within taxonomy. Understanding the unique characteristics of medicinal plant species is crucial for identifying their bioactive components and potential health benefits, contributing to herbal remedy formulations.

17) Table:
In scientific research, a table is a systematic arrangement of data or information presented clearly for analysis. Tables in studies often summarize findings, such as the identity and concentration of bioactive compounds found in plant extracts.

18) Study (Studying):
A study involves systematic inquiries into a research question, often following a structured methodology. The exploration of bioactive compounds in plants like Actiniopteris radiata through studies contributes to the scientific understanding of their medicinal properties and potential therapeutic applications.

19) Ghat (Gham):
Ghat typically refers to a set of steps leading down to a body of water, or in this context, it relates to the Western Ghats, a mountain range in India. The diverse flora found in these regions includes many medicinal plants and contributes to biodiversity.

20) Clerodendrum phlomidis:
Clerodendrum phlomidis is a plant known for its medicinal properties. Researching its bioactive components aids in understanding similar compounds in other medicinal species, enriching the knowledge base of phytochemicals and their therapeutic potentials.

21) Antibiotic (Antibacterial):
Antibacterial refers to substances that inhibit the growth of bacteria. The study of plant extracts for their antibacterial properties is crucial for developing natural remedies that can combat antibiotic-resistant strains and improve public health.

22) Civilization:
Civilization reflects the social and cultural development of societies throughout history, including their practices related to herbal medicine. Understanding the historical context of plant usage can reveal how traditional medicinal practices evolved and their relevance today.

23) Discussion:
Discussion conducts interpretation and analysis of research findings within a study. It provides insights into the implications of the discovered bioactive compounds, their activities, and how they contribute to medicinal applications and future research directions.

24) Flavonoid:
Flavonoids are a group of plant metabolites with antioxidant activity, often found in various herbs and commonly studied for their health benefits. Investigating flavonoids' presence in medicinal plants contributes crucial knowledge to developing health-promoting compounds.

25) Toxicity:
Toxicity assesses the harmful effects of substances on living organisms. Understanding the toxicity profile of bioactive compounds is essential for evaluating their safety for medicinal use and ensuring that traditional remedies are safe for consumption.

26) Relative:
Relative refers to the proportion or comparison of one entity in relation to another. In scientific analysis, understanding the relative abundance of compounds can provide insight into their significance in a particular extract and inform further research.

27) Vitiation (Vitiated):
Vitiated refers to a state of imbalance or disorder, often used in traditional medicine to describe a condition adversely affected by bodily humors such as Kapha and Pitta. Recognizing these states informs treatment practices in herbal medicine.

28) Quality:
Quality refers to the standard or degree of excellence of a substance or product. The quality of botanical extracts is critical in ensuring the efficacy and safety of medicinal products derived from plants.

29) Leprosy:
Leprosy is a chronic infectious disease that has been treated historically with herbal remedies. Researching medicinal plants can lead to the discovery of effective treatments that address diseases like leprosy, which remain relevant in traditional healthcare.

30) Peacock:
Peacock, in this context, relates to the common name given to Actiniopteris radiata (Peacock's tail). Its naming reflects cultural significance and aids in identifying the plant in traditional medicine practices, enhancing the importance of local flora.

31) Family:
In biological classification, family refers to a higher taxonomic group encompassing related genera. Understanding the family to which a plant belongs can provide insights into its characteristics, including potential medicinal values shared among its relatives.

32) Bitter:
Bitter is a taste perception often related to certain phytochemical compounds. Many medicinal plants have a bitter flavor, which can indicate the presence of bioactive ingredients that contribute to their therapeutic effects.

33) Indian:
Indian pertains to the cultural and geographic identity of India, where traditional medicinal practices have a significant role. The diversity of flora in India supports an extensive array of herbal remedies and phytochemical studies.

34) Pitta:
Pitta is one of the three doshas in Ayurveda representing fire and water elements. Conditions vitiated by Pitta are managed using various herbal remedies, thereby highlighting the importance of studying bioactive compounds from local plants in addressing these imbalances.

35) Kapha:
Kapha is another dosha in Ayurveda, characterized by earth and water elements. Understanding how plants can influence Kapha helps in designing herbal treatments aimed at balancing this dosha, showing the relevance of local flora in traditional healing practices.

36) Water:
Water is essential for life and often highlighted in the preparation of herbal medicine. It serves both as a solvent for extracting bioactive compounds from plants and as a component of remedies that require hydration for efficacy.

37) Fever:
Fever is a common symptom treated in traditional medicine, often associated with various ailments. Many herbal preparations are aimed at lowering fever, showcasing the therapeutic potential of bioactive compounds identified through scientific study.

38) Blood:
Blood is crucial for sustaining life and often serves as a context for various medicinal studies. Research into herbal remedies can reveal compounds that affect blood-related health conditions, enhancing the understanding of traditional medicines.

39) Acrid:
Acrid refers to a sharp, pungent taste or sensation, often related to certain phytoconstituents found in medicinal plants. This characteristic can indicate specific therapeutic properties that are leveraged in traditional remedies.

40) Sara (Shara):
Sara likely refers to a specific individual in the study, Catharin Sara S., contributing to the research discussed. Recognition of contributors is vital in scientific works, ensuring credit for collaborative research efforts.

41) Food:
Food encompasses various substances that nourish the body, including medicinal plants considered food in many cultures. The understanding of phytochemicals from edible plants aids in promoting health and fostering an integrative approach to wellness.

42) Rich (Rch):
Rich indicates abundance, often in regard to biodiversity or active compounds in extracts. The richness of a plant's chemical composition can lead to enhanced therapeutic properties, highlighting its value in herbal medicine.

43) Gold (Golden):
Gold metaphorically represents the high value or significance of something, akin to the untapped potential of plant-based remedies in pharmaceuticals and traditional medicine. This reference underlines the importance of ongoing research in uncovering valuable medicinal compounds.

44) Cori (Corii):
Sori are clusters of sporangia found on the lower surfaces of fern fronds. They are significant in the reproductive process of ferns and can be related to the search for medicinal components, emphasizing the unique biology of these plants.

45) Life:
Life encompasses the biodiversity found in ecosystems, including medicinal plants. The study of their chemical properties and applications contributes to understanding biological interactions and the role of flora in sustaining health and wellness.

Other Science Concepts:

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Discover the significance of concepts within the article: ‘GC-MS analysis of bioactive compounds in Actiniopteris radiata.’. Further sources in the context of Science might help you critically compare this page with similair documents:

Pesticide, Active principle, Chemical composition, Antibacterial activity, Antioxidant activity, Pharmacological activities, Phytochemical analysis, Anti-inflammatory, Phytotherapy, Hypocholesterolemic, Antifungal activity, Molecular weight, Hypocholesterolemic activity, Secondary metabolite, Ethanolic extract, Hepatoprotective, Bioactive compound, Traditional medicinal preparation, Molecular formula, GC-MS analysis, Mass spectrum, Gas Chromatography Mass Spectrometry, Crude extract, Cancer preventive, Hexadecanoic acid, Pharmaceutical Importance, Novel drug, 5-Alpha reductase inhibitor, Bioactive component, Traditional Practitioner, Phytoconstituent, Ethyl ester, Phytochemical constituent, Plant constituent, Heptadecanoic acid, Antiarthritic, Antihistaminic, Antiandrogenic.

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