RP-HPLC quantifies gallic acid in Emblica officinalis extracts.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “RP-HPLC quantifies gallic acid in Emblica officinalis extracts.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Emblica officinalis:
Emblica officinalis, commonly known as Amla, is a medicinal plant renowned for its numerous health benefits, including antioxidant, anti-inflammatory, and hepatoprotective properties. The study focuses on quantifying gallic acid in this plant's extracts to verify its authenticity in poly-herbal formulations. Its significance in traditional and modern medicine cannot be overstated.

2) Water:
Water is the primary solvent used in the extraction process of Emblica officinalis in this study. It acts as a medium to dissolve polar compounds, enabling the effective extraction of bioactive constituents, such as gallic acid. The quality of water is crucial for accurate and reproducible results in chromatographic analysis.

3) Powder:
Powder refers to the form of the dried fruit of Emblica officinalis that was ground before extraction. The conversion of the dried fruit into a fine powder increases the surface area, thereby enhancing the efficiency of the extraction process and ensuring that the active compounds are adequately released into the solvent.

4) Study (Studying):
The study aims to quantify gallic acid in the aqueous extract of Emblica officinalis and a poly-herbal capsule formulation. This research contributes to quality control and authenticity verification of herbal medicines, addressing the challenges of identifying specific components in complex multi-ingredient formulations commonly used in traditional medicine.

5) Drug:
In this context, 'drug' refers to the poly-herbal formulation that includes Emblica officinalis as one of its components. The investigation into the gallic acid content contributes to assessing the formulation's therapeutic efficacy and safety, thereby emphasizing the role of herbal drugs in complementary and alternative medicine.

6) Science (Scientific):
Science is fundamental in understanding the pharmacological effects and chemical profiles of medicinal plants like Emblica officinalis. Scientific methodologies, such as reverse-phase high-performance liquid chromatography (RP-HPLC), are employed in this study to ensure robust analysis and validation of findings, reinforcing the evidence-based approach in herbal medicine.

7) Delhi:
Delhi is mentioned in the study as the location of the Central Council for Research in Ayurvedic Sciences, where the research was conducted. As a hub for traditional medicine research, Delhi plays a crucial role in advancing studies related to Ayurveda which integrates ancient knowledge with modern scientific techniques.

8) Table:
Tables are utilized to present data clearly and concisely in scientific research. In this study, tables summarize results of gallic acid concentrations and chromatographic conditions, providing a quick reference for readers and highlighting the effectiveness of the analytical methods employed in quantifying the active components in the extracts.

9) Amla:
Amla is another name for Emblica officinalis, synonymous with its powerful health benefits. The fruit is widely celebrated in traditional medicine for its high vitamin C content and antioxidant properties. The study aims to quantify gallic acid, a key bioactive component of Amla, to support its therapeutic claims.

10) Calculation:
Calculation refers to the mathematical processes used to quantify the concentration of gallic acid in the extracts. Rigorous calculations, including regression analysis, are crucial for determining the precision and accuracy of the HPLC results, ensuring that the findings are statistically valid and reliable for drawing conclusions.

11) Terminalia chebula:
Terminalia chebula is another medicinal plant mentioned alongside Emblica officinalis. It is recognized for its health benefits and is part of the same family of plants that contain similar polyphenolic compounds. Including it in the context of this study emphasizes the variety and potency of herbal ingredients in poly-herbal formulations.

12) New Delhi:
New Delhi, as the capital of India and the location of significant Ayurvedic research institutions, is pivotal for advancing research in traditional medicine. The Central Council for Research in Ayurvedic Sciences operates in New Delhi, contributing to the development and validation of herbal medicines through studies like the one presented.

13) Terminalia bellirica:
Terminalia bellirica, like Terminalia chebula, is included in the study to highlight the presence of multiple herbal components in the formulation. It underscores the complexity of analyzing poly-herbal preparations, reinforcing the need for accurate quantification methods, such as RP-HPLC, to assure the quality and efficacy of herbal drugs.

14) Discussion:
The discussion section of the study interprets the results obtained from the HPLC analyses, contextualizing the significance of the findings in terms of quality control, authenticity, and therapeutic potential of the herbal formulation. This section connects the empirical evidence with existing literature and practical implications in herbal medicine.

15) Amlapitta (Amla-pitta):
Amlapitta is a traditional term for a digestive disorder akin to peptic ulcer, highlighting the relevance of Emblica officinalis in treating such conditions. The study relates the medicinal uses of Amla to its bioactive compounds, advocating for further research into its therapeutic roles in addressing gastrointestinal ailments.

16) Quality:
Quality in this context refers to the standards and processes that determine the efficacy and safety of herbal formulations. The study emphasizes the importance of quantifying gallic acid as a marker for the quality control of Emblica officinalis and its formulation, ensuring that traditional medicines meet health and safety regulations.

17) Heating:
Heating is a crucial step in the extraction process of Emblica officinalis, as it facilitates the dissolution of phytochemicals. The study indicates that controlled heating conditions for aqueous extraction optimize the yield of bioactive compounds, balancing efficiency with preservation of the plant’s medicinal properties.

18) Purity:
Purity signifies the extent to which the gallic acid extracted from Emblica officinalis is free from contaminants or adulterants. The study validates the purity of the compound by employing HPLC, thereby ensuring the integrity of the analyses and the authenticity of the herbal products being tested.

19) Indian:
Indian refers to the origin of both the Emblica officinalis plant and the traditional Ayurvedic system that utilizes it. The study contributes to the rich heritage of Indian medicinal practices by exploring scientifically the therapeutic roles of native plants that have long been used in folklore and traditional medicine.

20) India:
India is emphasized as the geographical and cultural context from which Emblica officinalis derives its significance. The study connects modern scientific inquiry with India’s traditional herbal medicine practices, highlighting the need for integrating herbal constituents like gallic acid into broader health systems and policies.

21) Ulcer:
Ulcer denotes the medical condition that Emblica officinalis is traditionally used to treat. The study confirms the presence of bioactive compounds that may effectively contribute to ulcer treatment, thus bridging the gap between traditional practices and modern scientific validation regarding the health claims associated with Amla.

22) Pati (Patin):
Padhi refers to one of the authors of the study, indicating collaboration among researchers in the field of Ayurvedic sciences. The involvement of multiple authors enhances the credibility and depth of the research, showcasing diverse expertise in validating herbal formulations and their therapeutic claims through scientific analysis.