Journal name: World Journal of Pharmaceutical Research
Original article title: Herbal remedies as alternative to antidiabetic and plants are available in bangladesh
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Subtitle: a comprehensive review
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Md. Reyad-ul-Ferdous, Almas Ahmmed, Md. Abu Hena Mostofa Kamal, Prawej Ansari, D.M. Shamim Shahjahan, Farhana Akter and Md. Hossan Sakib
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Herbal remedies as alternative to antidiabetic and plants are available in bangladesh
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
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Summary of article contents:
Introduction
The rising prevalence of diabetes in both developing and developed countries has led to an increased interest in herbal medicine as an alternative treatment. This paper highlights the effectiveness of various medicinal plants found in Bangladesh that have demonstrated antidiabetic activity. These plants have been utilized for centuries in traditional medicine, offering a natural approach to managing not only diabetes but also a range of other health conditions. The review underscores the potential of integrating herbal remedies into contemporary therapeutic strategies to better address this chronic disease.
The Role of Plant-Based Medicine in Diabetes Management
The use of plant-based medicines for treating diabetes has a long history, with certain plant extracts already contributing to the development of pharmaceutical treatments. For instance, guanidine derived from plants has been pivotal in the creation of biguanides, a widely-used oral antidiabetic medication. Current research extends to numerous herbs believed to assist in managing or preventing diabetes, suggesting that many of these natural compounds may empower traditional practices through scientific validation. However, it is advised that patients consult healthcare providers when considering herbal treatments, as interactions with prescribed medications can pose risks.
Efficacy of Specific Antidiabetic Plants
The review identifies several key plants with antidiabetic properties. For example, bitter melon contains lectins that exhibit insulin-like activity and may help manage blood glucose levels. Additionally, tulsi (holy basil) shows potential in treating high cholesterol and obesity, along with its antidiabetic effects. It is emphasized that while these plants can bring significant health benefits, users should be cautious due to possible adverse effects and contraindications associated with certain plant parts, particularly in specific populations such as children and pregnant women.
Future Directions in Antidiabetic Herbal Research
The continued rise in diabetes cases necessitates further exploration of herbal remedies. Despite the current medical reliance on insulin and synthetic drugs, researchers are increasingly looking toward the extensive biodiversity found in traditional medicine. There is a call for a deeper investigation into the ethnomedicinal herbs used by indigenous tribes to uncover potential new treatments. Such research could lead to the development of more targeted and safer antidiabetic agents derived from natural sources. This focus on plant compounds may also help address the lack of progress seen in conventional drug development for diabetes.
Conclusion
The review highlights that medicinal plants hold significant promise in the fight against diabetes and various related conditions. The existing body of research reflects a burgeoning interest in the pharmacological properties of these plants and their potential integration into modern medical practices. As diabetes continues to be a serious global health concern, there is a clear need for ongoing research into both the chemical properties and therapeutic actions of herbal remedies. This could lead to the discovery of innovative treatments that harness the vast array of phytochemicals found in nature, ultimately benefiting those affected by diabetes and offering safer alternatives to current pharmaceuticals.
FAQ section (important questions/answers):
What are the benefits of herbal remedies for diabetes management?
Herbal remedies may help regulate blood sugar levels, reduce side effects, and offer natural alternatives to conventional diabetes medications. Many traditional medicines derived from plants have demonstrated significant antidiabetic effects.
What are the common types of diabetes and their characteristics?
The two major types of diabetes are Type 1 and Type 2. Type 1 is autoimmune and leads to insulin deficiency, while Type 2 is often linked to lifestyle factors and insulin resistance, making up about 90% of diabetes cases.
Which plants are recognized for their antidiabetic properties?
Several plants, such as Momordica charantia (bitter gourd), Trigonella foenum-graecum (fenugreek), and Allium sativum (garlic), are noted for their antidiabetic effects and can be used in traditional medicine to manage diabetes.
What precautions should be taken when using herbal medicines?
Consulting a healthcare provider is crucial, as some herbs may interact with diabetes medications, potentially causing dangerously low blood sugar levels and unwanted side effects if combined without proper guidance.
What role do herbal medicines play in modern diabetes treatment?
Herbal medicines are gaining attention as potential alternatives or complements to conventional drugs. Their natural compounds may lead to the discovery of new treatment avenues, especially given the growing resistance to existing medication.
How significant is the research on herbal plants for diabetes?
Research on medicinal plants' effects on diabetes is emerging, with several studies validating their hypoglycemic activities. However, extensive exploration and clinical trials are needed to develop effective antidiabetic agents derived from these plants.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Herbal alternatives to antidiabetics in Bangladesh.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Drug:
Drug refers to any substance that produces a physiological effect when introduced into the body. In the context of diabetes, significant attention is drawn to both synthetic drugs and herbal alternatives derived from plants that may offer therapeutic benefits. The exploration of plant-based drugs is key in managing conditions like diabetes.
2) Disease:
Disease describes a pathological condition that impairs normal bodily functions. In the review, diabetes is highlighted as a chronic disease resulting from improper insulin action or production. Understanding various diseases is crucial in developing effective treatments and exploring herbal remedies as alternatives, particularly in a culturally rich context like Bangladesh.
3) Blood:
Blood plays a crucial role in the human body as it transports oxygen and nutrients, crucial for cellular function. In diabetes, blood glucose levels become a focal point, with herbal remedies notably affecting these levels. Effective management of blood sugar is essential in preventing complications related to diabetes.
4) Sugar:
Sugar, primarily glucose, is a vital energy source for the body. However, excessive levels can lead to health issues, including diabetes. This emphasizes the importance of managing dietary sugar intake along with exploring herbal remedies that might help regulate sugar levels naturally.
5) Diet:
Diet refers to the types and amounts of food consumed, profoundly affecting health. The research emphasizes the significance of plant-based diets in managing diabetes and highlights the interplay between diet choices and the effectiveness of herbal treatments in glycemic control.
6) Medicine:
Medicine encompasses various practices and treatments used to maintain health and manage diseases. The review assesses herbal medicines as alternatives to conventional treatments for diabetes, advocating for their efficacy and the necessity of rigorous scientific investigations into their benefits and potential risks.
7) Activity:
Activity, in this context, relates to the biological effects produced by substances, particularly those found in herbal plants. The antidiabetic activity of various plants signifies their potential in therapeutic applications, urging further research into their mechanisms of action.
8) Bitter:
Bitter often describes certain flavors present in some medicinal plants that can have therapeutic properties. For instance, bitter melon is highlighted for its insulin-like activity, promoting its use as a natural approach for managing diabetes through its unique phytochemical components.
9) Food:
Food serves as sustenance and is pivotal for health. The connection between food choices, especially plant-based options, and diabetes management is profiled, indicating that specific foods can positively influence glucose levels and overall health outcomes.
10) Pharmacological:
Pharmacological refers to the science of drugs and their effects on biological systems. The pharmacological properties of herbal remedies, such as their antidiabetic effects, warrant extensive research to translate these traditional practices into scientifically validated treatments.
11) Study (Studying):
Study denotes the systematic investigation of materials and phenomena. The review is indicative of a broader investigation into herbal remedies' efficacy and potential, emphasizing the importance of clinical studies to substantiate claims surrounding plants' health benefits.
12) Life:
Life encompasses the existence and health of individuals. The review stresses that medicinal plants remain vital for many, addressing health conditions like diabetes that profoundly impact quality of life, particularly in developing regions.
13) Animal:
Animal models are frequently used in research to evaluate the efficacy of treatments. The review highlights the need for studies on hypoglycemic activities in diabetic animal models to support the potential application of herbal remedies in human diabetes management.
14) Indian:
Indian refers to the geographical and cultural context where many medicinal plants originate. The review emphasizes exploring Indian traditional medicine practices and the rich biodiversity of plants used historically for managing conditions like diabetes.
15) Tulsi:
Tulsi (Holy Basil) is a revered herb in traditional medicine renowned for its numerous health benefits, including potential antidiabetic effects. The exploration of Tulsi's curative properties aligns with the broader theme of using herbal remedies to tackle modern health issues.
16) Chittagong:
Chittagong is a significant city in Bangladesh known for its rich biodiversity of medicinal plants. The region's unique flora contributes to the understanding and availability of herbal remedies, particularly those used in traditional medicine for various ailments, including diabetes.
17) Developing:
Developing denotes nations in stages of economic growth, often facing unique health challenges. The review indicates that in these regions, traditional herbal remedies might offer accessible alternatives to conventional medical treatments, addressing diseases such as diabetes more sustainably.
18) Science (Scientific):
Scientific refers to a systematic approach to understanding phenomena through research and observation. The call for scientific validation of herbal remedies signifies the importance of natural product research in creating effective and safe treatment modalities for conditions like diabetes.
19) Relative:
Relative indicates a comparison or association between entities. In diabetes research, it highlights connecting herbal treatments' efficacy with conventional medicine, exploring how traditional knowledge complements modern medical approaches in managing health conditions.
20) Cancer:
Cancer represents a group of diseases characterized by uncontrolled cell growth. Various medicinal plants are studied for their potential anticancer properties, indicating the need for broader exploration of natural remedies in treating multiple chronic diseases, including diabetes.
21) Ulcer:
Ulcer refers to a sore on the skin or mucous membrane, often chronic in nature. The review mentions herbal remedies exhibiting antiulcer properties, linking the role of these plants in holistic treatment strategies for various ailments alongside diabetes.
22) Table:
Table often refers to a systematic arrangement of data. The document includes a table listing various antidiabetic plants available in Bangladesh, showcasing the wealth of herbal resources utilized in traditional medicine for managing diabetes.
23) Death:
Death signifies the cessation of biological functions that sustain a living organism. The document references diabetes as a leading cause of death and underscores the urgency in developing effective treatments, especially through the lens of traditional herbal healing practices.
24) Tree:
Tree refers to perennial plants, many of which are sources of traditional medicine. The review touches on various trees like Pterocarpus marsupium and Aegle marmelos, highlighting their traditional uses and potential therapeutic benefits in managing health conditions such as diabetes.
25) Zingiber officinale:
Zingiber officinale, commonly known as ginger, is highlighted for its medicinal properties, particularly its antidiabetic effects. Its incorporation in treatment regimens for diabetes illustrates the relevance of traditional herbs in modern health strategies.
26) Azadirachta indica:
Azadirachta indica, or neem, is known for its vast medicinal properties, including antidiabetic effects. This plant is rooted in traditional medicine systems, emphasizing the importance of exploring such herbs for their potential therapeutic roles in contemporary health challenges.
27) Mangifera indica:
Mangifera indica, or mango, is another significant plant with traditional medicinal applications. Its leaves, in particular, are mentioned for their health benefits, reinforcing the narrative surrounding the exploration of plant-based remedies for managing diseases like diabetes.
28) Ocimum sanctum:
Ocimum sanctum, widely recognized as Holy Basil or Tulsi, is revered for its health benefits, particularly in traditional medicine. Highlighting this plant elucidates the importance of herbal options in managing chronic diseases such as diabetes.
29) Bitter gourd:
Bitter gourd, scientifically known as Momordica charantia, is noted for its antidiabetic properties. The active components in this bitter fruit are acknowledged for their insulin-like effects, promoting its use in diabetes management.
30) Momordica charantia:
Momordica charantia, or bitter gourd, is recognized for its role in managing diabetes due to its bioactive compounds that mimic insulin. This highlights the significance of integrating traditional food sources in diabetes treatment strategies.
31) Punica granatum:
Punica granatum, or pomegranate, is noted for its numerous health benefits, including potential antidiabetic effects. Its inclusion in the discourse on herbal treatments reflects the diverse sources available for managing diabetes and other chronic conditions.
32) Aegle marmelos:
Aegle marmelos, or bael fruit, is acknowledged for its medicinal properties, particularly relating to diabetes. Its traditional uses illustrate the potential of indigenous plants to contribute to modern therapeutic strategies for managing blood sugar levels.
33) Allium sativum:
Allium sativum, or garlic, is esteemed not only for culinary purposes but also for its health benefits, including antidiabetic properties. This underscores the relevance of common herbs in developing holistic health solutions, particularly in managing diabetes.
34) Dysmenorrhea (Dysmenorrhoea):
Dysmenorrhea, or painful menstruation, reflects the broader application of herbal remedies in women's health. The connection between general and specific health issues illustrates the potential benefits of medicinal plants in providing holistic treatment options.
35) Malnutrition:
Malnutrition indicates deficiencies in the intake of nutrients and can exacerbate various health conditions. The relationship between diet, especially the consumption of herbal remedies, and malnutrition emphasizes the role of food sources in maintaining overall health and managing diabetes.
36) Inflammation:
Inflammation is a biological response to harmful stimuli, often linked to chronic diseases, including diabetes. The review discusses how many medicinal plants possess anti-inflammatory properties, presenting herbal remedies as options for managing inflammation associated with various ailments.
37) Pomegranate:
Pomegranate, recognized for its rich nutrient profile and health benefits, is underscored for its potential roles in managing chronic diseases, including diabetes. This illustrates how widely consumed fruits can contribute to improving health outcomes.
38) Snake-bite:
Snake-bite refers to injuries inflicted by snake venom, for which various herbal treatments have been traditionally utilized. This reference highlights the knowledge and use of plants for diverse medical issues within traditional medicinal practices.
39) Blindness:
Blindness, often a complication of uncontrolled diabetes, emphasizes the serious consequences of the disease. The review underlines the importance of managing diabetes effectively to prevent such severe outcomes, advocating for the role of herbal therapies in treatment plans.
40) Ayurveda (Ayus-veda):
Ayurveda is a traditional Indian system of medicine that utilizes a holistic approach to health. The inclusion of Ayurvedic practices in addressing diabetes reflects the interconnection between ancient wisdom and contemporary treatment strategies using herbal remedies.
41) Pregnant:
Pregnant denotes a condition where a woman carries a developing fetus. The review indicates gestational diabetes and the importance of monitoring blood sugar levels during pregnancy, highlighting the need for safe and effective treatments, including herbal remedies.
42) Lucknow:
Lucknow is noted for its research in medicinal plants and their applications in treating various conditions, including diabetes. The reference to this city illustrates the geographical significance in the search for antidiabetic herbal solutions.
43) Species:
Species refers to distinct types of plants or organisms. The identification and study of various plant species that demonstrate antidiabetic properties is crucial for developing effective herbal treatments and understanding their unique contributions to health.
44) Mineral:
Mineral substances are vital for various bodily functions, and their deficiencies may contribute to diseases. The review hints at the importance of considering nutritional components, including minerals in plant-based treatments for health conditions like diabetes.
45) Davana:
Davana refers to a medicinal plant with historical usage in traditional medicine. Exploring such plants contributes to the understanding of their therapeutic properties, including their potential impact on managing conditions like diabetes.
46) Family:
Family denotes the classification of plant species sharing common characteristics. Identifying the familial relationships of medicinal plants aids in understanding their medicinal potential and encourages the exploration of related species for antidiabetic applications.
47) Garlic:
Garlic, known scientifically as Allium sativum, is highlighted for its numerous health benefits, particularly its antidiabetic properties. This reflects the significant role of commonly used culinary herbs in complementing approaches to diabetes management.
48) Costus:
Costus refers to a genus of plants with potential medicinal properties. Highlighting such lesser-known plants in discussions surrounding diabetes treatment emphasizes the breadth of herbal options available in traditional medicine systems.
49) Cilli:
Chilli, often used in cooking, is noted for its numerous health benefits. Its inclusion in traditional medicinal practices ties into the broader exploration of plant-based treatments for managing various health conditions, including diabetes.
50) Methi:
Methi, or fenugreek, is a well-known herb celebrated for its health benefits, including its antidiabetic effects. This highlights the relevance of commonly consumed herbs in the exploration of natural treatments for metabolic disorders.
51) India:
India is a significant focal point for traditional medicine and herbal remedies, with a wealth of biodiversity. Engaging with India’s rich traditions in herbal medicine offers critical insights into potential treatments for diseases such as diabetes.
52) Fever:
Fever indicates an increase in body temperature often due to infection or illness. The connection between herbal treatment and fever management illustrates the holistic nature of plant-based medicine, where multiple ailments are addressed concurrently.
53) Mango:
Mango, particularly its leaves, is recognized for medicinal properties, including potential benefits for diabetes management. The exploration of such fruits presents a holistic view of nutrition's role in health, especially regarding chronic diseases.
54) Neem:
Neem is revered in traditional medicine for its antimicrobial and antidiabetic properties. This highlights the significance of indigenous plants in contemporary health solutions, reflecting the growing interest in herbal approaches.
55) King:
King, in the context of 'King of Bitters' (Andrographis paniculata), indicates the medicinal importance of certain plant names that connote their significant health benefits. This underscores the valuable role of traditional designations in the study of herbal medicine.
56) Rice (Rce):
Rice serves as a staple food providing energy and essential nutrients. Its role in various traditional remedies underscores the potential synergy between diet and herbal treatment in managing health issues such as diabetes.
57) Rich (Rch):
Rich describes the abundance of beneficial compounds often found in medicinal plants. Characterizing plants as rich in certain phytochemicals emphasizes their potential in developing effective herbal treatments for various diseases, particularly diabetes.
58) Road:
Road may metaphorically indicate a path forward in research or treatment within the medicinal field. The reference serves to emphasize the ongoing journey of integrating traditional knowledge with scientific inquiry to unveil new therapeutic possibilities.
59) Line:
Line can indicate a connection or aspect of a study. In this context, it suggests the interrelation between different herbal remedies and their potential in addressing a myriad of health concerns, including diabetes.
60) Burning (Burn, Burned, Burnt):
Burn may relate to wounds or skin conditions that herbal remedies also aim to treat. This highlights the multifaceted capabilities of medicinal plants, showcasing their diverse applications in traditional medicine.
61) Pur:
Poor refers to individuals with limited access to healthcare resources. Exploring traditional and herbal remedies for managing conditions like diabetes becomes more vital in impoverished areas where pharmaceutical options may not be readily accessible.