Phytochemical screening and antioxidant efficacy of Acanthophora spes.
Journal name: World Journal of Pharmaceutical Research
Original article title: Screening of phytochemical and in vitro antioxidant efficacy on selected red seaweed (acanthophora specifera) collected from gulf of mannar, tamilnadu, india
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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R.Rajesh Kumar and K.Jeyaprakash
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Screening of phytochemical and in vitro antioxidant efficacy on selected red seaweed (acanthophora specifera) collected from gulf of mannar, tamilnadu, india
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
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Summary of article contents:
Introduction
The study investigates the phytochemical constituents and in vitro antioxidant properties of Acanthophora specifera, a species of red seaweed collected from the Gulf of Mannar, Tamil Nadu, India. As a potential renewable resource from the marine environment, seaweeds are recognized for their rich bioactive compounds that hold significant medicinal potential, including antioxidant and antimutagenic properties. Different extracts of Acanthophora specifera were prepared using methanol, ethanol, and water for analysis, resulting in the methanolic extract displaying the highest phytochemical content.
Phytochemical Composition of Acanthophora specifera
The study demonstrates that Acanthophora specifera contains various phytochemicals, such as tannins, saponins, flavonoids, steroids, terpenoids, alkaloids, amino acids, polyphenols, and glycosides. Preliminary qualitative screening indicated that the methanolic extract of the seaweed showed the maximum diversity and concentration of these phytochemicals, which suggests its potential utility as a natural source of antioxidants. The quantitative analysis revealed that the total phenolic content was 217.59 mg/g and total flavonoids was 124.87 mg/g, emphasizing the extracts' significant phytochemical richness.
In Vitro Antioxidant Activity
In vitro antioxidant assays were conducted to evaluate the scavenging effects of the methanolic extract of Acanthophora specifera against various free radicals. The DPPH radical scavenging activity was particularly notable, with 76.31% inhibition observed at 80 µg/ml concentration. Other assays, including hydroxyl radical scavenging (79.81% inhibition) and superoxide anion scavenging (73.41% inhibition), further confirmed the extract's robust antioxidant capacity. These results suggest that the presence of phenolic and flavonoid compounds plays a key role in moderating oxidative stress, which is associated with numerous human diseases.
Antioxidant Mechanisms and Implications
The research explores multiple mechanisms by which Acanthophora specifera exerts its antioxidant effects. The ability to chelate ferrous ions (Fe²⁺) and enhance reducing power showcases the extract's potential to mitigate oxidative damage in biological systems. Through various assays such as nitric oxide radical scavenging and reducing power, the study emphasizes the defensive role of the bioactive compounds in Acanthophora specifera against oxidative stress. These mechanisms underline the significance of the seaweed not only as a food supplement but also in potential therapeutic applications.
Conclusion
The present study establishes Acanthophora specifera as a promising natural source of bioactive compounds with notable antioxidant properties. Its phytochemical richness and ability to scavenge free radicals suggest potential applications in nutraceuticals and functional foods. As a conclusion, the findings advocate for further investigations into this marine resource to explore its broader medicinal implications, reinforcing the importance of sustainable use of marine biodiversity for health benefits.
FAQ section (important questions/answers):
What is the primary focus of the study on Acanthophora specifera?
The study investigates the phytochemical profile and in vitro antioxidant properties of the red seaweed Acanthophora specifera, collected from the Gulf of Mannar, Tamil Nadu, India.
What types of extracts were prepared for the antioxidant analysis?
Methanol, ethanol, and water extracts of Acanthophora specifera were prepared to analyze their phytochemical content and antioxidant properties.
Which extract showed the maximum phytochemical constituents in the study?
The methanolic extract exhibited the highest presence of phytochemical constituents compared to the ethanol and water extracts.
What major phytochemicals were identified in Acanthophora specifera?
The study identified tannins, saponins, flavonoids, steroids, terpenoids, alkaloids, amino acids, polyphenols, anthraquinones, and glycosides in the extracts.
How effective was the methanolic extract’s DPPH radical scavenging activity?
The methanolic extract demonstrated a DPPH radical scavenging inhibition of 76.31% at a concentration of 80 µg/ml, indicating significant antioxidant activity.
What conclusion did the authors draw about Acanthophora specifera?
Acanthophora specifera may serve as a rich source of natural antioxidants, potentially beneficial for health due to its phytochemical content.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Phytochemical screening and antioxidant efficacy of Acanthophora spes.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Activity:
Activity refers to the various biological actions exhibited by compounds in the extracts of Acanthophora specifera, particularly in relation to their potential as antioxidants. This highlights the capability of these natural substances to mitigate oxidative stress, which is essential in various therapeutic areas, including nutrition and medicine.
2) Water:
Water is a crucial solvent used in the extraction processes of phytoconstituents from Acanthophora specifera. As a fundamental substance for life, water helps in dissolving various compounds, facilitating chemical reactions, and maintaining the ecological balance of marine environments where red seaweeds thrive. Its presence in studies emphasizes its role in extraction protocols.
3) Table:
Table refers to the organized presentation of data in the study, illustrating the results of phytochemical screening and antioxidant activities. Tables make complex information easily digestible and allow for comparative analysis of different extracts, contributing to clearer interpretations of findings and making the data accessible for further research.
4) Study (Studying):
Study denotes the scientific investigation performed on Acanthophora specifera, aiming to explore its phytochemical and antioxidant properties. Scientific studies are essential for validating claims regarding the health benefits of natural products, providing a foundation for future research, and potentially leading to novel medical applications or therapies.
5) Phytochemical:
Phytochemicals are bioactive compounds found in plants, such as tannins, flavonoids, and saponins. The relevance of phytochemicals lies in their potential health benefits, including antioxidant, anti-inflammatory, and antimicrobial properties. Understanding phytochemicals in Acanthophora specifera enhances knowledge about their nutritional and therapeutic value and their role in disease prevention.
6) Flavonoid:
Flavonoids are a significant class of phytochemicals known for their antioxidant properties. They play a key role in protecting cells from oxidative damage and inflammation. The presence of flavonoids in Acanthophora specifera emphasizes its potential utility in the development of natural health products and functional foods aimed at promoting human health.
7) Tamilnadu (Tamil-nadu):
Tamilnadu is a state in India where the research was conducted, particularly in the Gulf of Mannar region. This geographical context is important as it highlights the ecological diversity and rich marine life in the area, which contributes to the unique composition of phytochemicals found in local seaweeds like Acanthophora specifera.
8) India:
India is the country where the red seaweed Acanthophora specifera was collected and studied. Its diverse climate and rich biodiversity support various medicinal plants and seaweeds. The cultural significance of natural remedies in India underlines the importance of local flora in traditional medicine and the potential for modern therapeutic applications.
9) Species:
Species refers to a specific group of organisms, in this case, Acanthophora specifera, which is a type of red seaweed belonging to the family Rhodomelaceae. Understanding the specific species is crucial in assessing the potential health benefits, ecological roles, and conservation measures necessary for preserving biodiversity.
10) Thanjavur:
Thanjavur is a city in Tamilnadu, India, associated with the study's authors and their affiliations. Its relevance lies in the educational and research institutions that contribute to the exploration of local natural resources, fostering scientific advancements in the fields of biochemistry and medicinal research pertaining to seaweeds.
11) Antibiotic (Antibacterial):
Antibacterial refers to substances that combat bacteria. This term is relevant in highlighting the potential of Acanthophora specifera to possess antibacterial properties as evidenced by its phytochemical composition. This capability aligns with the increasing demand for natural alternatives to synthetic antibiotics in treating bacterial infections.
12) Medicine:
Medicine encompasses the field dedicated to the diagnosis, treatment, and prevention of diseases. The findings from this study on Acanthophora specifera contribute to the medicinal understanding of natural products, highlighting their potential use in formulating new therapies and supplements for enhancing health and treating various ailments.
13) Disease:
Disease refers to pathological conditions affecting the normal functioning of the body. The study's focus on antioxidant properties of Acanthophora specifera suggests its relevance in mitigating oxidative stress-related diseases, which may have implications for prevention and treatment strategies aimed at promoting overall health and wellbeing.
14) Cancer:
Cancer represents a category of diseases where abnormal cells divide uncontrollably. The antioxidant properties explored in Acanthophora specifera may have implications for cancer prevention or treatment by combating oxidative stress, which is a known factor in cancer progression, thus revealing the potential therapeutic applications of seaweeds.
15) Powder:
Powder refers to the dried and ground form of Acanthophora specifera used for extract preparation in the study. The form of a substance can significantly affect its bioavailability and efficacy in medicinal applications, making the powdered state vital for standardization and optimal extraction of active compounds.
16) Kumar:
Kumar refers to R. Rajesh Kumar, one of the researchers involved in the study. The individual contributions of researchers are crucial in advancing scientific knowledge, and recognizing their efforts promotes accountability and acknowledgment in the scientific community for the studies and findings they produce.
17) Cina:
China is not directly related to the study but may represent a broader context in discussions about seaweed research and its applications. Comparisons to other countries can provide insights into global practices, advancements in biotechnology, and the regulatory frameworks governing seaweed harvesting and utilization for health benefits.
18) Food:
Food refers to substances consumed for sustenance and nourishment. The findings regarding the antioxidant properties of Acanthophora specifera indicate its potential use in food products to enhance nutritional value, shelf life, and health benefits, contributing to the growing interest in functional foods and nutraceuticals.
19) Rich (Rch):
Rich refers to the abundance of phytochemicals and beneficial compounds found in Acanthophora specifera. The term highlights the seaweed's potential as a valuable resource for health supplements and natural antioxidants, promoting its usage in various applications due to its high nutritional and therapeutic value.
20) Dish (Dis):
Dish refers to a prepared meal or food item. The relevance of Acanthophora specifera extends to culinary applications where its antioxidant properties may enhance food quality and flavor. Integrating seaweeds into traditional dishes reflects cultural practices and the rising trend toward nutritious and healthy eating.
21) Discussion:
Discussion pertains to the section of the study where the implications of the findings are analyzed. It's crucial for interpreting results, providing context, and suggesting future research directions, allowing for deeper understanding and potential applications of the study's outcomes in fields such as pharmacology and nutrition.
22) Substance:
Substance refers to any material with observable properties, including the phytochemicals extracted from Acanthophora specifera. Understanding the characteristics of various substances is vital in assessing their efficacy and safety in medical and dietary applications, thus influencing their potential roles in health improvement and disease prevention.
23) Toxicity:
Toxicity relates to the degree a substance can harm organisms. Evaluating the toxicity of plant extracts, including Acanthophora specifera, is essential in determining their safety for consumption and therapeutic use, ensuring that they offer beneficial effects without adverse health consequences.
24) Quality:
Quality pertains to the standard of a product, which in the context of the study, relates to the extracts derived from Acanthophora specifera. High-quality extracts are essential for ensuring consistent therapeutic benefits, emphasizing the importance of rigorous testing of phytochemical content and biological activities.
25) Habitat:
Habitat refers to the natural environment where organisms live, such as the marine coastal areas from which Acanthophora specifera is sourced. Understanding habitats is crucial for conservation efforts and sustainable harvesting practices, ensuring that natural resources are available for future research and applications.
26) Mineral:
Mineral refers to essential elements found in seaweeds, such as magnesium and calcium, which contribute to their nutritional value. The presence of minerals in Acanthophora specifera enhances its potential as a dietary supplement, underscoring the importance of seaweeds as a source of vital nutrients for human health.
27) Science (Scientific):
Science refers to the systematic study of the structure and behavior of the physical and natural world through observation and experimentation. The research on Acanthophora specifera exemplifies the application of scientific methodology to uncover valuable knowledge about natural products and their potential applications in health and medicine.
28) Family:
Family, in botanical terms, refers to the classification of related plant species; in this case, Rhodomelaceae encompasses Acanthophora specifera. Understanding the family classification helps in recognizing the characteristics and potential uses of the species, facilitating broader research into similar organisms within the same category.
29) Reason:
Reason pertains to the justification behind conducting research, such as understanding Acanthophora specifera's antioxidant properties. Research is driven by a quest for knowledge, motivating scientists to explore potential health benefits, which can lead to significant advancements in medicine, nutrition, and environmental sustainability.
30) Animal:
Animal refers to multicellular organisms, often studied to assess the biological effects of substances derived from plants. The relevance of animals in this context is critical in establishing the efficacy and safety of phytonutrients like those from Acanthophora specifera through in vivo and in vitro testing methodologies.
31) Pearl:
Pearl in this context could symbolize value and purity, reminiscent of the valuable properties associated with specific extracts from Acanthophora specifera. Although pearls are not directly related to the study, the analogy indicates the preciousness of natural compounds unlocked through scientific research and their applications in health.
32) Hand:
Hand signifies the manual aspect of research, such as the careful collection, processing, and analysis of Acanthophora specifera. The term embodies the dedication and meticulous effort of researchers in studying natural products, emphasizing human intervention in the discovery and utilization of bioactive ingredients.
33) Shand (Sand):
Sand refers to the sediment often found in the marine environments where Acanthophora specifera thrives. Understanding the ecological aspects, such as the influence of substrate on seaweed growth, aids in grasping their natural habitat and the dynamics of their ecosystem, which is essential for sustainable harvesting practices.
34) Burning (Burn, Burned, Burnt):
Burn relates to the potential applications of Acanthophora specifera in wound healing as suggested by its phytochemical properties. Traditional medicine often utilizes plants for treating burns and injuries, and the study highlights the significance of exploring natural remedies derived from seaweeds for enhancing skin health and recovery.
35) Life:
Life signifies the biological processes and interactions among organisms, including the role of Acanthophora specifera in maintaining ecological balance. Understanding life in the context of biodiversity underscores the importance of protecting natural environments and the species within them to ensure the sustainability of natural resources and health benefits.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Phytochemical screening and antioxidant efficacy of Acanthophora spes.’. Further sources in the context of Science might help you critically compare this page with similair documents:
Traditional medicine, Wound healing, Conflict of interest, Chemical composition, Anti-inflammatory activity, Antioxidant activity, Preliminary phytochemical screening, Nutritional Quality, Phytochemical screening, Lipid peroxidation, Anti-cancer activity, Anti-microbial activity, Radical Scavenging Activity, Anti-allergic activity, Medicinal potential, Total phenolic content, Hydrogen peroxide, Reducing power assay, Nitric oxide, Bioactive compound, Superoxide anion, Antibiotic activity, Ferric-reducing antioxidant power assay, Nitric oxide radical, Nitric oxide scavenging activity, Antioxidant efficacy, DPPH Radical Scavenging Assay, In vitro antioxidant, Hydroxyl radical scavenging activity, Free radical scavenger, DPPH radical, DPPH free radical scavenging activity, Natural antioxidant, Phosphate buffer saline, Iron chelating activity, Hydroxyl radical, Superoxide anion radical, Phytoconstituent, Presence of tannin.
Concepts being referred in other categories, contexts and sources.