Mycological profile of onychomycosis in kenitra city (morocco)
Journal name: World Journal of Pharmaceutical Research
Original article title: Mycological profile of onychomycosis in kenitra city (morocco)
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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A.Aiboud, A.Ouichou, A. El Hessni1, A.Fllaoui, M.Lahlou, J. Koufane, S.Masmoudi, M. Lakhmiri and A. Mesfioui
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Full text available for: Mycological profile of onychomycosis in kenitra city (morocco)
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
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Summary of article contents:
1) Introduction
Onychomycosis is a fungal infection of the nails that is primarily caused by dermatophytes, yeasts, or molds, impacting about 2% to 26.9% of the general population. The true prevalence of this infection in Morocco is likely underestimated due to high treatment costs, which restrict mycological examinations necessary for confirming the diagnosis. In Kenitra, where the study was conducted, the aim was to ascertain the mycological profile of onychomycosis and identify the most frequently occurring fungal agents.
2) Prevalence and Patient Demographics
The study observed that the prevalence of onychomycosis in Kenitra was notably high, with 62.5% (25 out of 40 patients) confirmed to have the infection. A significant majority of affected individuals were women (77.5%) between the ages of 31 and 60 years. This demographic trend aligns with findings from other studies that highlight the age group’s susceptibility due to prolonged exposure to fungal agents and lifestyle factors, such as wearing tight shoes or engaging in sports that may facilitate contamination.
3) Fungal Identification and Common Pathogens
The mycological examination revealed that dermatophytes were the primary causative agents of onychomycosis, representing 79.16% of the cases. The predominant species was found to be Trichophyton rubrum, accounting for 94.73% of the dermatophyte infections. In contrast, yeast infections were relatively rare, with Candida albicans being the only species identified, affecting 7.5% of the total cases. The species distribution underscores the importance of identifying specific pathogens to tailor appropriate treatment strategies.
4) Diagnosis and Methodology
The study employed a comprehensive diagnostic approach that included both direct examination and culture techniques to confirm the presence of fungal infections. Direct examination was positive in 62.5% of cases, and culture confirmed fungal growth in 55%. Nail samples were meticulously collected and examined using potassium hydroxide for direct microscopy and Sabouraud agar for culture, ensuring reliable fungal identification. The methodology highlights the necessity of accurate diagnostic procedures in managing nail infections effectively.
5) Conclusion
In conclusion, the findings from this study indicate that onychomycosis is a prevalent cause of nail disease in Kenitra, with T. rubrum being the most frequently isolated pathogen. The infection predominantly affects women, particularly in the age group of 31 to 60 years, and is observed mostly in toenails. These insights into the epidemiological and mycological profile of onychomycosis in the region can inform public health efforts and improve treatment practices for this common ailment.
FAQ section (important questions/answers):
What is onychomycosis and its common causes?
Onychomycosis is a fungal infection of the nail, typically caused by dermatophytes, yeasts, or molds. It affects 2-26.9% of the general population, with dermatophytes being the most common culprits.
What was the prevalence of onychomycosis in the study?
The study found a 62.5% prevalence of onychomycosis among 40 patients, predominantly affecting women and adults aged 31 to 60 years.
Which species of fungi was most commonly identified?
Trichophyton rubrum was the most commonly identified species, accounting for 94.73% of dermatophyte cases in the study, followed by T. mentagrophytes.
Where did the patients in the study come from?
Patients in the study were from various regions of Kenitra city, Morocco, consulting for suspected nail onychomycosis due to visible clinical signs.
How was mycological examination conducted in the study?
Samples were collected through nail scraping, followed by direct examination with potassium hydroxide and culture on Sabouraud media under specific incubating conditions for fungal identification.
What does the study conclude about onychomycosis in Kenitra?
The study concludes that onychomycosis is prevalent in Kenitra, primarily caused by dermatophytes, with T. rubrum being the most common, and highlights the predominance in women.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Mycological profile of onychomycosis in kenitra city (morocco)”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Study (Studying):
The keyword 'Study' relates to the systematic investigation conducted to understand the mycological profile of onychomycosis in Kenitra city, Morocco. It encompasses the research methodology, patient selection, data collection, laboratory analyses, and the evaluation of results. The findings contribute valuable insights into the prevalence and causative agents of this fungal nail infection, helping to inform healthcare practices and improve patient management.
2) Species:
The term 'Species' refers to the specific types of fungi identified in the study, particularly dermatophytes and yeasts. In the context of onychomycosis, it highlights the importance of recognizing distinct fungal agents like Trichophyton rubrum and Candida albicans, as the species involved can influence treatment approaches, prognosis, and epidemiological understanding of the infection's prevalence.
3) Table:
The keyword 'Table' signifies the structured presentation of data collected during the study, summarizing key findings such as the distribution of patient demographics, the prevalence of onychomycosis, and the species isolated. Tables facilitate quick reference and comprehension of data, allowing for clearer interpretation of results and comparisons within the text, which is essential for scientific communication.
4) Hand:
The word 'Hand' denotes the anatomical location in which fungal infections may arise, particularly mentioned in the context of onychomycosis affecting fingernails. The study primarily focused on toenails but acknowledged that nail infections can also occur on hands, influencing clinical diagnosis and treatment strategies. This highlights the need for comprehensive assessments in dermatological practices.
5) Science (Scientific):
The term 'Science' relates to the systematic study of the natural world, including the examination of fungal infections like onychomycosis. It emphasizes the empirical methodologies employed in the study, such as mycological examinations, to explore fungal etiology and develop evidence-based conclusions for medical research, contributing to advances in understanding and treating nail diseases.
6) Disease:
The keyword 'Disease' pertains to the medical conditions that arise due to fungal infections like onychomycosis. It emphasizes the impact of these infections on the quality of life, presenting clinical signs such as thickening of nails, detachment, or deformities. Understanding the disease's etiology, prevalence, and management is crucial for effective healthcare interventions.
7) Medium:
'Medium' refers to the growth substrates used for culturing fungi in the laboratory. In this study, Sabouraud medium supplemented with antibiotics was utilized to enhance the isolation of fungal species. Proper culture media are essential for successful diagnostics of onychomycosis, aiding in identifying the specific fungi responsible for the infections, which informs treatment protocols.
8) Tuni:
'Tuni' might be a typographical error for 'Tunisia,' which is referenced in the study concerning the prevalence of onychomycosis and dermatophyte species. The comparative aspect presents insights from different geographic locations, enhancing the understanding of onychomycosis etiology and epidemiology, reflecting regional patterns and risk factors associated with fungal nail infections.
9) Transmission:
The term 'Transmission' describes the process through which fungal infections are spread among individuals. In this study, it encompasses the means by which dermatophytes like Trichophyton rubrum are acquired, such as exposure to contaminated surfaces in communal environments like showers and swimming pools. Understanding transmission dynamics aids in developing prevention strategies and public health awareness.
10) Discussion:
The word 'Discussion' signifies the section of the study where results are interpreted, analyzed, and contextualized within existing literature. It involves evaluating the implications of the data, comparing findings with previous studies, and contemplating the broader significance of the results to enhance understanding of onychomycosis and advocate for appropriate clinical practices and further research.
11) Detachment:
The keyword 'Detachment' refers to one of the clinical signs observed in onychomycosis where the nail separates from the nail bed. This condition is essential for diagnostic considerations, affecting treatment decisions and patient management. Recognizing the symptoms, including detachment, allows healthcare providers to differentiate onychomycosis from other nail disorders for accurate treatment.
12) Antibiotic (Antibacterial):
'Antibiotic' denotes substances used to inhibit the growth of microorganisms, especially in culture media. In the study, chloramphenicol was added to the culture medium to prevent bacterial contamination during fungal isolation. The use of antibiotics in mycological studies is crucial to ensure the integrity of fungal cultures and improve diagnostic accuracy in onychomycosis.
13) Affection:
The word 'Affection' in the study context refers to a medical condition or disease affecting the nails, specifically onychomycosis. It highlights the burden of fungal infections on individuals and emphasizes the importance of addressing such conditions in medical practice. Understanding the nature of nail affections can lead to improved patient outcomes through better diagnosis and treatment.
14) Medicine:
The term 'Medicine' refers to the science and practice of diagnosing, treating, and preventing diseases. In this study, it encompasses the therapeutic approaches for managing onychomycosis, including antifungal treatments. Understanding the medical aspects of fungal infections is essential for developing effective treatment protocols and improving patient care in clinical settings.
15) Activity:
The word 'Activity' may refer to the lifestyle factors contributing to the incidence of onychomycosis, such as physical activity leading to moisture and trauma to the nails. Understanding these activities allows health professionals to identify risk factors for fungal infections and advise patients on preventive measures to reduce the likelihood of developing onychomycosis.
16) Summer:
The term 'Summer' relates to the seasonal climate conditions, which may impact fungal growth and the prevalence of onychomycosis. The study indicates the influence of environmental factors, including temperature and humidity, on the incidence of nail infections, suggesting that certain conditions may facilitate fungal transmission and affect public health in specific regions.
17) Sign:
The word 'Sign' refers to the observable clinical indicators of onychomycosis, such as discoloration, thickening, and detachment of the nails. Recognizing these signs is critical for early diagnosis and effective treatment, emphasizing the need for thorough examinations in patients suspected of having fungal nail infections and the importance of public awareness regarding nail health.
18) Soil:
The term 'Soil' signifies an environmental factor relevant to the transmission of fungi, especially dermatophytes that thrive in moist, organic-rich substrates. The connection between soil and fungal infections supports the notion of exposure to contaminated environments contributing to onychomycosis. Understanding environmental reservoirs of fungi enhances awareness of prevention and mitigation strategies for at-risk populations.
19) Dish (Dis):
The word 'Dish' refers to the sterile Petri dishes used for collecting and culturing nail samples in the laboratory. Proper handling and use of dishes are vital for maintaining aseptic conditions during fungal isolation. The choice of appropriate laboratory equipment ensures accurate results in identifying fungal species responsible for onychomycosis, crucial for effective diagnostics and treatment.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Mycological profile of onychomycosis in kenitra city (morocco)’. Further sources in the context of Science might help you critically compare this page with similair documents:
Main cause, Direct examination, Age-group, Candida albicans, Epidemiological data, Fungal infection, Dermatophytes, Risk factor, Clinical sign, Trichophyton rubrum, Culture media, C. albicans, Average age, Onychomycosis, Kenitra city, Epidemiological profile, Population characteristics, Demographic development, Nail lesion, Macroscopic and microscopic character, Nail disease, Mycological examination, Nail dystrophy, Sabouraud medium, T. rubrum, T. mentagrophytes, Moroccan population.