Review of atibala (abutilon indicum) for its pharmacological properties
Journal name: World Journal of Pharmaceutical Research
Original article title: Review of atibala (abutilon indicum) for its pharmacological properties
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Asutkar Rupali Dumantraj, Kharat Ravindra S, Ghotankar Aparna M, Chincholikar Mukesh B.
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Full text available for: Review of atibala (abutilon indicum) for its pharmacological properties
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
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Summary of article contents:
1) Introduction
Abutilon indicum, commonly known as Atibala, is a significant medicinal plant belonging to the Malvaceae family. It has been widely recognized in Ayurveda, where all its parts are used to treat various ailments. Ancient texts, including those by Charaka and Sushruta, have acknowledged the plant’s medicinal importance. Both Acharya Charaka and Acharya Sushruta included Atibala in their classifications of important herbs, highlighting its role in enhancing vitality, treating illnesses, and supporting overall health.
2) Pharmacological Properties
One of the vital areas of research concerning Abutilon indicum is its diverse pharmacological activities. Modern studies have identified a plethora of properties, including anti-estrogenic, immunomodulatory, anti-diabetic, analgesic, anti-inflammatory, and wound healing activities. The plant’s extract has demonstrated significant effects in various experimental models, including suppression of estradiol-induced responses in ovariectomized rats and improvements in immune responses in mice. These findings underscore Atibala's potential role as a natural remedy supporting various health conditions.
3) Anti-Diarrheal and Gastrointestinal Effects
Another noteworthy aspect of Abutilon indicum is its anti-diarrheal properties. Extracts from the leaves have shown effective results in studies involving castor oil-induced diarrhea and prostaglandin E2-induced enteropooling in rats. The mechanisms behind its efficacy appear to involve the inhibition of intestinal peristalsis, thereby reducing the frequency of diarrhea. This traditional use aligns with Ayurvedic classifications of Atibala, which emphasize its roles as a Grahi (astringent) and Krimighna (anti-parasitic), further highlighting its relevance in digestive health.
4) Hepatoprotective Activity
Abutilon indicum also exhibits significant hepatoprotective effects, demonstrated by its ability to protect against liver damage induced by carbon tetrachloride (CCl4) in animal models. Studies reported reductions in liver enzyme levels and overall improvement in liver function parameters following treatment with the plant’s extracts. This protective activity contributes to its traditional uses in managing various liver-related ailments and reinforces the integrative approach of combining modern pharmacological insights with ancient wisdom.
5) Conclusion
In conclusion, Abutilon indicum, or Atibala, presents a striking example of how traditional herbal medicine aligns with modern scientific research. The exploration of its pharmacological properties shows promise across multiple therapeutic areas, including its roles as an anti-diarrheal, hepatoprotective, and immunomodulatory agent. The convergence of Ayurvedic knowledge and contemporary studies highlights the medicinal value of Atibala, establishing it as a crucial subject of ongoing research aimed at better understanding its full potential as a natural remedy.
FAQ section (important questions/answers):
What is Abutilon indicum commonly known as?
Abutilon indicum is commonly referred to as Atibala and is recognized for its significant medicinal properties in traditional Ayurvedic medicine.
What are some traditional uses of Atibala?
Atibala is traditionally used for various ailments, including treatments for gastrointestinal issues, respiratory problems, and as a restorative herb in Ayurveda for strength and immunity.
What pharmacological activities does Atibala exhibit?
Atibala exhibits numerous pharmacological activities, including anti-estrogenic, anti-diarrheal, anti-asthmatic, immunomodulatory, wound healing, anti-ulcer, hepatoprotective, analgesic, and antioxidant activities among others.
How does Atibala impact diabetes management?
Atibala shows significant hypoglycemic effects, aiding in lowering blood glucose levels and enhancing insulin secretion, making it beneficial for diabetes management.
Are there any anti-inflammatory properties of Abutilon indicum?
Yes, Abutilon indicum has demonstrated anti-inflammatory properties, effectively reducing inflammation in various experimental models, thereby helping with conditions like arthritis.
What part of Abutilon indicum is used for medicinal purposes?
Almost all parts of Abutilon indicum, including its leaves, flowers, and roots, are utilized for their medicinal properties in traditional and modern herbal medicine.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Review of atibala (abutilon indicum) for its pharmacological properties”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Activity:
Activity refers to the various pharmacological effects exhibited by Abutilon indicum (Atibala). The document highlights multiple activities such as anti-diarrheal, anti-inflammatory, wound healing, and cardioprotective effects, which are significant in traditional medicine and modern pharmacological research.
2) Atibala:
Atibala, the common name for Abutilon indicum, is noted for its medicinal properties in both traditional Ayurvedic practices and contemporary studies. Recognized for its utility in various ailments, Atibala is an integral part of Ayurvedic herbal formulations and is referenced frequently in classical texts.
3) Nighantu (Nighamtu):
Nighantu refers to a traditional Ayurvedic glossary or pharmacopoeia that lists medicinal plants, their properties, and uses. The text references several Nighantus, which provide important information about the therapeutic applications of Atibala and reinforce its significance in Ayurvedic medicine.
4) Ulcer:
Ulcer, particularly in the context of this study, pertains to conditions affecting the gastrointestinal tract. The document discusses the anti-ulcer activity of Atibala, indicating its potential to prevent or heal ulcers, which is a crucial aspect of its medicinal prowess.
5) Study (Studying):
Study denotes the research and evaluation conducted on the properties and effects of Atibala (Abutilon indicum). The review encompasses various experimental and clinical investigations that substantiate its traditional uses and explore its effectiveness in different pharmacological applications.
6) Balya:
Balya is an Ayurvedic term indicating the property of promoting strength and vitality. Atibala is categorized under Balya in Ayurvedic texts, emphasizing its role in health promotion, particularly for children and individuals recovering from illness, highlighting its traditional significance.
7) Pharmacological:
Pharmacological pertains to the study of drugs and their effects on biological systems. The document explores the pharmacological properties of Atibala, detailing its various applications and implications within the domain of modern pharmacotherapy and traditional medicine.
8) Krimighna (Krmighna, Krimi-ghna):
Krimighna is an Ayurvedic term meaning 'antimicrobial' or 'destroyer of parasites.' The document mentions Crimighna in relation to Atibala, indicating its historical use in treating infections and its potential efficacy in modern antimicrobial applications.
9) Sharman (Sarma, Sharma, Sarman):
Sharma is a common surname (often of Indian origin) associated with scholars and practitioners in the field of Ayurveda and traditional medicine. The document cites several researchers named Sharma, who contributed to the study of Abutilon indicum and its medicinal properties.
10) Grahin (Grahi):
Grahi is an Ayurvedic concept signifying the property of being 'absorptive' or 'binding.' In the document, it describes how Atibala is utilized for its potential to control diarrhea and promote digestion, emphasizing its beneficial effects on gastrointestinal health.
11) Vishaghna (Visaghna, Visha-ghna):
Vishaghna refers to the property of neutralizing poisons or toxins. The text indicates that Atibala possesses Vishaghna properties, highlighting its applications in detoxifying the body and treating conditions caused by toxin exposure, reinforcing its medicinal value.
12) Varanasi (Varanashi):
Varanasi is a historic city in India, well-known as a cultural and spiritual center. The text mentions Varanasi as the publication location associated with numerous Ayurvedic studies, underscoring its importance in traditional learning and medicinal practices.
13) Science (Scientific):
Science in this context refers to the systematic study of the physical and natural world through observation and experimentation. The document discusses the scientific validation of traditional uses of Atibala, bridging ancient practices with modern pharmacological research.
14) Varṇya (Varnya):
Varnya, an Ayurvedic term meaning 'good for the skin' or 'enhancing complexion,' indicates Atibala's properties related to skin health. The document highlights its potential use in beauty treatments and skin conditions, aligning with its traditional applications in Ayurveda.
15) Indian:
Indian references the cultural and geographical context wherein Atibala (Abutilon indicum) is indigenous. The plant plays a significant role in traditional Indian medicine and highlights the country's rich heritage of herbal pharmacology and Ayurveda.
16) Kushthaghna (Kusthaghna):
Kushthaghna refers to the property of treating skin diseases or leprosy. The document mentions that Atibala has Kushthaghna properties, noting its use in traditional healing practices for dermatological issues, underlining its historical significance.
17) Kandughna (Kandu-ghna):
Kandughna is an Ayurvedic term referring to the property of relieving itching or skin irritations. The document identifies Atibala as Kandughna, emphasizing its applications in treating various skin-related ailments and enhancing its therapeutic profile.
18) Hridya (Hrdya):
Hridya stands for heart-related properties in Ayurveda, suggesting that Atibala can be beneficial for cardiac health. The text presents evidence of its cardio-protective activities, affirming its role in contemporary medicinal applications.
19) Edema (Oedema):
Edema denotes swelling caused by excess fluid trapped in the body's tissues. The document evaluates Atibala's potential effects on reducing inflammation, indicating its medical relevance in managing conditions that cause edema.
20) Drug:
Drug signifies a substance used for medical treatment or diagnosis. The document highlights Atibala as a natural drug with a range of therapeutic effects, pointing to its significance in both traditional and modern medicine.
21) Phytochemical:
Phytochemical refers to chemical compounds produced by plants, often with medicinal properties. The study investigates various phytochemicals present in Atibala that contribute to its pharmacological effects, underscoring its potential in drug development.
22) Ayurveda (Ayus-veda):
Ayurveda is an ancient Indian system of medicine grounded in holistic health principles. The document discusses Atibala's integration into Ayurvedic practices, highlighting traditional medicinal uses and the historical context of its applications.
23) Toxicity:
Toxicity refers to the degree to which a substance can harm humans or animals. The document assesses the safety and potential toxicity of Atibala extracts, providing an essential safety perspective for its medicinal use.
24) Species:
Species relates to a specific group of organisms distinguished from others by particular characteristics. Abutilon indicum represents a significant species in herbal medicine, explored for its diverse benefits in the document's studies.
25) Castor:
Castor refers to the caster oil plant, often used in pharmacological studies to induce diarrhea in experimental settings. The document employs castor oil to analyze the anti-diarrheal effects of Atibala in animal models.
26) Family:
Family in a biological context denotes a group of related plants. Abutilon indicum belongs to the Malvaceae family, and the document examines its characteristics and properties as influenced by its familial relations.
27) Taila (Thaila):
Taila means 'oil' in Sanskrit and denotes herbal oils used in Ayurvedic treatments. The document references Atibala taila highlighting its methods of application and therapeutic uses based on traditional formulations.
28) Mridu (Mrdu):
Mridu refers to the property of being 'gentle' or 'mild' in Sanskrit. The document attributes Mridu properties to Atibala, emphasizing its safety and efficacy for treatments, including its use in gentle laxatives.
29) Kumar:
Kumar, a commonly used surname in India, also refers to 'youth' or 'child' in Sanskrit. The document alludes to scholars named Kumar to underscore contributions from various researchers to the studies of Atibala.
30) Water:
Water is essential for life and is often an essential component in herbal preparations. The document discusses various aqueous extracts of Atibala, evaluating their properties and applications in traditional and modern medicine.
31) Blood:
Blood relates to the body's circulatory system and overall health. The document investigates the effects of Atibala on blood health, particularly concerning its effects on hemoglobin and other hematological parameters.
32) Beta:
Beta may refer to beta-sitosterol, a phytochemical isolated from Atibala. The text highlights its potential therapeutic effects, particularly in the context of larvicidal activity against mosquito larvae, showcasing Atibala's multifaceted pharmacological benefits.
33) Diet:
Diet pertains to the food and nutrition consumed by organisms. In the context of the document, diet is studied concerning its impact on pharmacological effects and the use of Atibala for dietary-related health issues.
34) Bronchial asthma:
Bronchial asthma is a chronic condition characterized by airway inflammation and obstruction. The document presents evidence of Atibala's anti-asthmatic activity, validating traditional claims about its effectiveness in managing respiratory ailments.
35) Dhanvantarinighantu (Dhanvantari-nighantu):
Dhanvantari-nighantu is a classical Ayurvedic text describing medicinal herbs. The document references it to elucidate the properties and uses of Atibala, connecting it to authoritative sources in traditional medicine.
36) Kaiyadevanighantu (Kaiyadeva-nighantu):
Kaiyadeva-nighantu is another authoritative source in Ayurvedic literature that catalogs medicinal properties of plants. The document cites it to support claims regarding the therapeutic effects of Atibala, integrating traditional knowledge.
37) Sushruta-samhita (Susruta-samhita):
Sushruta-samhita is a seminal Ayurvedic text attributed to the ancient physician Sushruta. The document refers to its teachings and descriptions of Atibala, linking the plant to established historical medical practices.
38) Dhanvantari (Dhanvamtari):
Dhanvantari is considered the 'father of Ayurveda' and is revered in Indian medicine. The document signifies his contributions to herbal medicine and the relevance of texts associated with him in studying Atibala.
39) Sutrasthana (Sutra-sthana):
Sutrasthana is a section in the Sushruta-samhita. The document notes references from this part to highlight specific therapeutic uses of Atibala, underlining its legacy in traditional healing.
40) Mudhagarbha (Mudha-garbha):
Mudhagarbha denotes a particular medical condition addressed in Ayurveda. The text mentions it to illustrate how Atibala can be utilized based on traditional descriptions for treating this condition.
41) Observation:
Observation refers to the systematic process of measuring and noting effects in research. The document includes observations from various studies on Atibala, highlighting the importance of empirical evidence in validating traditional uses.
42) Balataila (Bala-taila):
Bala-taila refers to a specific herbal oil often used in treatments for children and nourishing formulations. The document associates Atibala with Bala-taila to exemplify its applications in gentle care for vulnerability and health.
43) Discussion:
Discussion involves analyzing and interpreting findings from research studies. In the document, the discussion section delves into the implications of Atibala's pharmacological properties, linking ancient wisdom to modern therapeutic practices.
44) Srivastava (Shri-vastava, Shrivastava, Sri-vastava):
Srivastava is a common surname in India that may relate to various researchers in the context. The document references individuals named Srivastava whose studies have contributed to understanding Atibala's medicinal properties.
45) Toxicology:
Toxicology refers to the study of the adverse effects of substances on living organisms. The document examines the safety and toxicity of Atibala extracts, ensuring their suitability for medicinal use according to scientific evaluations.
46) Flavonoid:
Flavonoid denotes a class of phytochemicals with potential health benefits. The document discusses flavonoids present in Atibala that contribute to its therapeutic properties, highlighting their role in modern pharmacological research.
47) Vallabha:
Vallabha is a name often associated with scholars and practitioners of Ayurveda. The document may cite Vallabha in relation to contributions or references found in Ayurvedic literature and research on Atibala.
48) Vagbhata:
Vagbhata was a notable ancient Ayurvedic scholar known for texts that address herbal medicine. The document likely references Vagbhata to validate the historical context and significance of Atibala in classical teachings.
49) Surendra (Sura-indra, Suremdra):
Surendra is a common Indian name possibly linked to researchers or practitioners mentioned in the text. The document may highlight contributions from individuals named Surendra concerning studies on the effects of Atibala.
50) Kasaghna (Kasa-ghna):
Kasaghna indicates the property related to treating cough or respiratory ailments. The document classifies Atibala as having Kasaghna activity, signifying its role in alleviating respiratory symptoms, enhancing its medicinal relevance.
51) Medicine:
Medicine refers to the science of diagnosing, treating, and preventing diseases. The document emphasizes Atibala's role in both traditional and modern medicine, highlighting its therapeutic potential across various health conditions.
52) Sanskrit:
Sanskrit is the ancient classical language of India used in traditional texts, including Ayurvedic literature. The document incorporates Sanskrit terms to convey the historical and cultural understanding of Atibala's uses and benefits.
53) Incision:
Incision relates to surgical methods involving cutting tissue. The document discusses incision models used in testing the wound healing properties of Atibala, showcasing its efficacy in promoting recovery from surgical wounds.
54) Skandha (Skamdha, Skamda):
Skandha, in Ayurvedic terminology, denotes a specific group or cluster of herbs. The document might use 'Skandha' to refer to traditional classifications that include Atibala among other medicinal plants for specific therapeutic benefits.
55) Samhita:
Samhita refers to collections of knowledge compiled into treatises, particularly in Ayurvedic texts. The document mentions Samhita to establish the authority and foundational context for the medicinal uses of Atibala.
56) Bhedana:
Bhedana is an Ayurvedic term related to procedures or treatments intended for surgical intervention, often involving incision or division. The document addresses Bhedana when discussing potential applications of Atibala, reinforcing its historical relevance.
57) Anupana:
Anupana signifies an adjuvant taken along with medicines to improve absorption or effectiveness. The document elucidates Anupana as important in traditional preparations involving Atibala, enhancing its therapeutic applications.
58) Marathi:
Marathi is a regional language in India, commonly spoken in Maharashtra. The document references Marathi terms to provide a local understanding of Atibala, highlighting its cultural significance in traditional medicine in the region.
59) Nagappa:
Nagappa is commonly a surname that may belong to researchers or practitioners from the Ayurvedic field cited in the text. The document likely points to their contribution to the study of Atibala's medicinal properties.
60) Pasana (Pashana):
Pashana refers to a category of Ayurvedic herbs typically used for lithotripsy (breaking down stones) or other remedies. The document mentions Pashana in conjunction with Atibala to illustrate its association with treatments for specific ailments.
61) Dravya:
Dravya literally means 'substance' or 'material' in Sanskrit. The document uses Dravya to classify various components involved in Ayurvedic pharmacology, particularly in discussing the formulations surrounding Atibala.
62) Vaidya:
Vaidya is a term for a physician in Ayurveda and traditional medicine. The document highlights Vaidyas as essential practitioners who have historically utilized Atibala for its health benefits, advocating its importance in healing practices.
63) Varsha (Varsa):
Varsha is a common Indian name and may refer to scholars or contributors mentioned in the text. The document draws attention to individuals named Varsha related to studies on the effects and benefits of Atibala.
64) Petari:
Petari is a regional name in Marathi for Atibala, reflecting local vernacular terminology. The document uses Petari to provide insight into cultural references and the familiarity of Atibala among different communities.
65) Aureus:
Aureus likely refers to a species of fungus or bacterium mentioned in the context of antifungal activity associated with Atibala. The document discusses the effectiveness of Atibala extracts against such pathogens, further establishing its medicinal relevance.
66) Kanghi:
Kanghi is another regional name for Atibala in Hindi, denoting its local significance. The document employs Kanghi to emphasize the cultural knowledge surrounding Atibala and its various uses in traditional remedies.
67) Kakahi:
Kakahi is also a vernacular name associated with Atibala in different regional languages. The document highlights such names to depict the plant’s integration into community health practices across India.
68) Animal:
Animal relates to biological studies often performed on laboratory animals to evaluate the effects of substances, such as Atibala. The document discusses various animal models used to determine the therapeutic efficacy of extracts.
69) Powder:
Powder indicates the form in which Atibala can be prepared for consumption. The document discusses powdered preparations in traditional medicine to enhance bioavailability and make administration easier for therapeutic purposes.
70) Madhu:
Madhu translates to honey in Sanskrit and is often used in Ayurvedic formulations as an adjuvant. The document refers to Madhu in conjunction with Atibala, illustrating its traditional use to enhance taste and efficacy.
71) Mutra:
Mutra pertains to urine in Ayurvedic terminology, often associated with urinary health. The document touches on the properties of Atibala for urinary issues, indicating its applications in managing such conditions.
72) Delhi:
Delhi, India’s capital, appears as a geographic reference in the context of Ayurvedic studies. The document associates various research activities related to Atibala originating from Delhi, signifying its academic importance.
73) Simha:
Sinha is a common surname in India, associated with various scholars and practitioners. The document acknowledges contributors named Sinha in relation to their research on Abutilon indicum, reinforcing the collaborative nature of the study.
74) India:
India denotes the country of origin for Atibala and its significant traditional knowledge system around herbal medicine. The document emphasizes Indian practices regarding Atibala, connecting it to the broader context of health and wellness.
75) Mudra:
Mudra in Ayurvedic context typically implies actions or positions that promote health. The document discusses Mudra as a therapeutic concept that can be related to certain practices utilizing Atibala's benefits.
[Note: The above list is limited to 75. Total glossary definitions available: 86]
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