Delayed-release tablet formulation and evaluation of aspirin USP.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Delayed-release tablet formulation and evaluation of aspirin USP.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Table:
A table in this context refers to a structured format for presenting data and results clearly. Tables are crucial in scientific research as they organize large amounts of information, such as measurements, parameters, and findings from the study, making it easier for readers to comprehend and analyze the results at a glance.

2) Drug:
A drug is a substance used for medical purposes, particularly to diagnose, cure, treat, or prevent disease. In the researched formulation, Aspirin serves as the drug being studied. Understanding the properties and effectiveness of the drug is essential for developing effective medicinal products and ensuring patient safety.

3) Powder:
Powder refers to the physical form of a substance that is finely ground, which can affect its solubility, stability, and bioavailability in tablet formulations. The powdered form of drugs and excipients enables better mixing and consistent dosages. Particle size and flow properties of the powder can influence the manufacturing process.

4) Study (Studying):
A study refers to a systematic investigation or analysis of a subject or phenomenon. In this context, it entails the formulation, development, and evaluation of delayed-release Aspirin tablets. Scientific studies are conducted to establish the efficacy and safety of drugs, ensuring they meet regulatory standards before reaching consumers.

5) Discussion:
Discussion in a scientific paper involves interpreting the results, explaining their implications, and comparing findings with previous research. It helps contextualize the study within the broader scientific community. This section critically assesses the methodology, findings, and potential applications of the research, contributing to scientific knowledge and future studies.

6) Vinayaka:
Vinayaka Mission’s College of Pharmacy is an educational institution located in Tamil Nadu, India, where this research was conducted. The institution plays a pivotal role in training pharmacy professionals and conducting innovative research. The college provides resources and support for students and faculty to explore pharmaceutical sciences and drug development.

7) India:
India is the country where the research was conducted. It has a large pharmaceutical industry known for its production of generic drugs and research initiatives. The country’s regulatory framework and growing focus on research and development are significant for advancements in pharmaceutical formulations, enhancing global health outcomes.

8) Substance:
A substance refers to a specific material or compound with distinct properties. In pharmaceutical research, the term often pertains to active pharmaceutical ingredients (APIs) and excipients used in drug formulations. Understanding the chemical and physical properties of a substance is critical for developing effective medications that are safe for consumption.

9) Calculation:
Calculation in this context refers to the quantitative analysis performed during the study, such as determining assay values, release percentages, and other crucial metrics. Accurate calculations are essential for validating the results, ensuring that the formulations meet therapeutic targets, and maintaining compliance with pharmacopeial standards.

10) Observation:
Observation entails the systematic noting of specific events or behaviors throughout the study. In research, observations lead to valuable insights regarding the stability, efficacy, and other characteristics of the drug formulations. This data is crucial for assessing how well the dosage forms perform under various conditions over time.

11) Performance:
Performance refers to how well the drug formulations achieve their desired outcomes in terms of release profiles, dissolution rates, and stability over time. The performance metrics help establish whether a formulation meets therapeutic objectives and regulatory requirements, thereby influencing its potential for clinical use.

12) Tamilnadu (Tamil-nadu):
Tamil Nadu is a state in India where the research was conducted. It is known for its educational institutions, including Vinayaka Mission’s College of Pharmacy. The region’s emphasis on higher education and research in the pharmaceutical sector contributes to advancements in drug development and healthcare improvements.

13) Shalem (Salem, Salem):
Salem is a city in Tamil Nadu, India, that hosts Vinayaka Mission’s College of Pharmacy. The location is relevant to the research as it provides the necessary educational resources, infrastructure, and a supportive environment for conducting pharmaceutical research and training future professionals in the field.

14) Tamil:
Tamil refers to the language predominantly spoken in Tamil Nadu, India. The cultural and linguistic identity of the region enriches the educational and scientific environments. Understanding local languages can enhance communication among researchers, educators, and the community, facilitating better collaboration and dissemination of scientific knowledge.

15) Nadu:
Nadu is part of the name 'Tamil Nadu' and refers to the state in Southern India. The state's dedication to developing education and healthcare systems influences research opportunities. The regulatory environment in Tamil Nadu supports pharmaceutical innovations, ensuring access to quality medications and advancing public health.

16) Heating:
Heating refers to the application of temperature changes during the manufacturing process of pharmaceutical formulations. Controlled heating can influence the properties of drug-excipient mixtures, affecting their behavior during processing and stability. Proper heating methods are essential for ensuring uniformity and quality in drug formulations.

17) Medium:
Medium refers to the solvent or environment used for dissolution testing, such as 0.1N Hydrochloric acid or buffer solutions. The choice of medium is critical in assessing the solubility and release characteristics of drug formulations, reflecting how they may behave in the gastrointestinal tract.

18) Water:
Water is a universal solvent integral to many pharmaceutical processes, including dissolution and stability testing. In this research, purified water is used for disintegration tests and as a medium to simulate the body’s environment. Its purity and quality are vital for obtaining accurate and reproducible results.

19) Life:
Life, in the context of pharmaceuticals, often refers to the bioavailability and therapeutic effectiveness of drugs in living organisms. Ensuring that drug formulations enhance the quality of life for patients is a primary goal of pharmaceutical research, which focuses on safety, efficacy, and patient adherence to treatments.

20) Irritation:
Irritation refers to the adverse effects that medications can have on the gastrointestinal tract or other tissues. Avoiding irritation is essential when formulating delayed-release tablets, as it enhances patient compliance and wellbeing. The research focused on mitigating such issues by using enteric coatings in the tablet formulation.

21) Knowledge:
Knowledge implies the understanding and insights gained from research activities. In pharmaceutical sciences, knowledge encompasses drug formulation, development processes, and the pharmacological properties of substances. It is paramount for advancing drug therapy and creating effective patient-centered medication regimens.

22) Disease:
Disease pertains to any abnormal condition affecting the body, which pharmaceutical research aims to address through effective drug formulations. The development of medications like Aspirin targets various conditions, such as pain, inflammation, and cardiovascular diseases, directly influencing public health and treatment strategies on a global scale.

23) Purity:
Purity indicates the extent to which a substance is free from contaminants and impurities. In pharmaceutical formulations, ensuring high purity levels of active ingredients and excipients is crucial for guaranteeing safety and efficacy. Purity assessments are a part of the quality control measures during drug development.

24) Nature:
Nature, in a scientific context, often refers to the intrinsic properties and characteristics of substances. Understanding the nature of drugs and excipients, including their physical and chemical behaviors, is fundamental for successful formulation development and enhancing the overall performance of pharmaceutical products.

25) House:
House can refer metaphorically to the institution or laboratory where research occurs. It encompasses the environment and facilities conducive to scientific discovery and drug development, fostering collaboration among researchers and creating an atmosphere for innovative thinking and breakthroughs in pharmaceuticals.

26) Cage:
Cage may refer to a containment or design element in laboratory settings, potentially referencing how substances are handled or analyzed under controlled conditions. In various experimental procedures, ensuring that samples remain undisturbed or contained is crucial for accurate data collection and validity of results.

27) Post:
Post indicates a phase following a certain action, such as post-compression or post-manufacturing studies. In pharmaceutical research, post-process evaluations are essential for assessing the stability, efficacy, and overall quality of formulations, ensuring they meet Established Pharmacopeial specifications before reaching consumers.