Hypertension prescribing patterns and quality of life in a hospital
Journal name: World Journal of Pharmaceutical Research
Original article title: Prescribing patterns and health related quality of life in patients with hypertension in a tertiary care hospital
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Dr. STK Sridhar, Dr. P Archana Rao, Dr. P Deepak, Dr. Rajesh Venkataraman
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Prescribing patterns and health related quality of life in patients with hypertension in a tertiary care hospital
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Copyright (license): WJPR: All rights reserved
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Summary of article contents:
Introduction
The study conducted by Sridhar et al., published in the World Journal of Pharmaceutical Research, aimed to evaluate the prescribing patterns and health-related quality of life (HRQoL) of patients with hypertension at a tertiary care hospital in Karnataka, India. Hypertension, affecting a significant portion of the global adult population, is often referred to as the "silent killer" due to its asymptomatic nature that can lead to serious health complications. The research focuses on understanding the effectiveness of single and combination drug therapies while measuring improvements in patients' quality of life using the European Questionnaire-5 Dimension (EQ-5D) scale.
Prescribing Patterns in Hypertensive Patients
The study reveals that calcium channel blockers emerged as the most commonly prescribed single drug therapy, accounting for 62% of prescriptions. Following this, Angiotensin Receptor Blockers (ARBs) represented 26.4%, with Angiotensin Converting Enzyme (ACE) inhibitors and beta blockers making up smaller percentages. Additionally, when looking at combination therapies, the most frequently prescribed pair was diuretics combined with ARBs at 47%, followed by calcium channel blockers paired with beta blockers at 30%. This underscores a trend toward a preference for calcium channel blockers and diuretics in managing hypertension, reflecting findings from other studies in the field.
Health-Related Quality of Life Assessment
Using the EQ-5D scale, the researchers assessed patients' HRQoL pre- and post-admission. Notably, patients aged 30-49 demonstrated significant improvements in mobility, self-care, usual activities, pain/discomfort, and anxiety levels post-admission, with a 100% rate of reported normality across all five dimensions upon discharge. In contrast, older patients, particularly those above 70, exhibited poorer HRQoL scores, indicating that age plays a critical role in how hypertension affects quality of life. The improvements observed in various dimensions highlight the impact of effective treatment and management on patients' overall well-being.
Age and Weight as Risk Factors
The authors analyzed the demographic data and noted that the majority of hypertensive patients were within the age group of 51-70 years, with a mean age of 57.1 years. Weight analysis indicated that individuals weighing between 60-75 kg were more susceptible to hypertension development. These findings emphasize the need for targeted interventions and monitoring for middle-aged and older adults, especially those within specific weight ranges, to mitigate the risk of hypertension and its associated complications.
Conclusion
In conclusion, this study underscores the importance of effective medication management and lifestyle modifications in enhancing health-related quality of life in hypertensive patients. The advancements in HRQoL before discharge indicate substantial benefits from the prescribed therapies. These findings suggest that compliance with antihypertensive treatment is crucial for controlling high blood pressure, preventing its progression, and maintaining an improved quality of life. Continuous evaluation and individualized treatment plans remain essential components in the management of hypertension.
FAQ section (important questions/answers):
What was the aim of the study on hypertension?
The study aimed to evaluate prescribing patterns and assess health-related quality of life in hypertensive patients using the European Questionnaire-5 Dimension scale.
What were the most prescribed medications for hypertension in the study?
Calcium channel blockers were most commonly prescribed as mono therapy (62%), followed by Angiotensin Receptor Blockers (26.4%) and Angiotensin Converting Enzyme inhibitors (9.19%).
How did patients' health-related quality of life change post-admission?
Patients demonstrated significant improvements in all five dimensions of health-related quality of life after admission, reflected by enhanced self-care, usual activities, and reduced pain and anxiety.
What were the inclusion criteria for the study?
The study included in-patients newly diagnosed with hypertension, aged between 20 to 80 years, with no severe comorbidities, and who provided consent.
What were common patient demographics in the study?
The study involved 50 patients, equally split between males and females, with a mean age of 57.1 years, predominantly within the 51-70 age group.
What role does lifestyle modification play in managing hypertension?
Lifestyle modifications, along with medication compliance, are crucial for effectively controlling hypertension and enhancing health-related quality of life for patients.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Hypertension prescribing patterns and quality of life in a hospital”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Drug:
The term 'Drug' in this context refers to medications prescribed for the treatment of hypertension. Different classes of drugs such as calcium channel blockers, beta-blockers, and diuretics are highlighted to illustrate their effectiveness in managing blood pressure and improving patients' health-related quality of life.
2) Table:
'Table' refers to the organized presentation of data within the study. Tables summarize patient demographics, prescribing patterns, and health-related quality of life assessments. They facilitate easy comparison and analysis of results, allowing for clearer communication of findings related to the study's objectives.
3) Quality:
'Quality' pertains to the standard of health-related life outcomes measured in the study. Health-related quality of life (HRQoL) indicators include dimensions like mobility, pain, and emotional well-being, assessing how hypertension and its treatment affect patients’ overall health and day-to-day functioning.
4) Life:
'Life' represents the existence and well-being of patients affected by hypertension. The study emphasizes how hypertension impacts different aspects of life, including physical, emotional, and psychological dimensions, and aims to improve life quality through effective management and treatment regimens.
5) Study (Studying):
'Study' denotes the research conducted to analyze prescribing patterns and health-related quality of life in hypertensive patients. This prospective observational study provides insights into medication effects, patient demographics, and post-admission quality of life improvements, highlighting the importance of effective hypertension management.
6) Channel:
In the context of hypertension treatment, 'Channel' refers to 'calcium channel blockers,' which are a category of medications used to manage high blood pressure. Their role is crucial as the study identifies them as the most frequently prescribed class of drugs, affecting health outcomes significantly.
7) Beta (Bēṭa, Beṭa):
'Beta' signifies beta-blockers, a specific class of antihypertensive medication. These drugs are essential in managing heart rate and blood pressure. Their mention in the study serves to compare their usage against other classes of drugs for hypertension management and overall treatment effectiveness.
8) Pain (Paiṇ):
'Pain' is one of the dimensions evaluated in the Health-related Quality of Life questionnaire. It assesses how hypertension and its treatments affect patients' experiences of discomfort. Understanding pain levels is vital for comprehensive patient care and tailoring effective treatment strategies.
9) Anxiety:
'Anxiety' is another dimension explored in assessing health-related quality of life. The study examines how hypertension influences patients’ mental health and emotional states, highlighting the importance of addressing psychological factors in conjunction with physical health in hypertensive patients.
10) Male (Mālē):
'Male' indicates one of the genders represented in the patient demographic of the study. The equal distribution of males and females (50% each) emphasizes the inclusivity of the research and allows for a balanced understanding of hypertension prevalence and treatment effects across genders.
11) Post:
'Post' refers to the period after patient admission, focusing on health-related quality of life evaluations following treatment. The comparison of pre- and post-admission outcomes provides insights into the effectiveness of interventions on various health dimensions and overall patient well-being.
12) Science (Scientific):
'Science' in this context relates to the systematic study of health and disease, particularly focusing on hypertension. The methodology of the research, including observational and analytical techniques, reflects a scientific approach to understanding the disease impacts and effective treatment regimes.
13) Depression:
'Depression' is an emotional state that may relate to the mental well-being of hypertensive patients. The study examines this dimension as part of the health-related quality of life assessment, acknowledging that managing hypertension also involves treating psychological conditions that could affect patients' health outcomes.
14) Karnataka (Karṇāṭaka):
'Karnataka' is a state in India where the study was conducted. It indicates the geographical context of the research, providing insight into local healthcare practices, demographic characteristics, and prescribing patterns specific to this region’s population with hypertension.
15) Activity:
'Activity' refers to usual activities assessed in the quality of life questionnaire, which examines how hypertension affects patient engagement in day-to-day functions. Evaluating activity levels is important for understanding the disease's impact on patients’ independence and lifestyle.
16) Nagara (Nāgara, Naga-ra, Nagarā):
'Nagara' is part of the location 'B.G. Nagara,' where the research was conducted. It highlights the specific setting of the study within Karnataka, reflecting local healthcare environments and patient populations relevant to hypertension treatment.
17) India:
'India' denotes the country where the study takes place, providing a broader context for understanding health practices and challenges in treating hypertension. It emphasizes the significance of regional health statistics and insurance factors regarding hypertension prevalence and care.
18) Mental health:
'Mental health' encompasses psychological well-being, which is crucial in assessing quality of life in patients with hypertension. The study acknowledges the interplay between mental and physical health, emphasizing the need for comprehensive treatment addressing both aspects for hypertensive patients.
19) Venkataraman (Veṅkatarāman):
'Venkataraman' refers to one of the authors involved in this research, indicating the collaborative nature of the study. Having multiple contributors with expertise fosters thorough analysis and a well-rounded understanding of hypertension management and health-related quality of life.
20) Discussion:
'Discussion' is an essential section of the study where findings are interpreted. It explores the implications of the results, compares them with previous research, and suggests future directions for studying hypertension treatment outcomes and strategies for improving patient care.
21) Developing:
'Developing' relates to countries or regions where healthcare systems are still evolving. The study highlights that a significant percentage of hypertensive individuals are from low-to-middle-income countries, emphasizing the challenges faced in managing hypertension in developing communities and the need for targeted interventions.
22) Pregnant:
'Pregnant' refers to a specific population excluded from the study due to potential complications in hypertension treatment and management. It underscores the necessity of considering unique health conditions when conducting research and tailoring treatments for hypertensive patients to ensure safety and efficacy.
23) Disease:
'Disease' generally signifies hypertension, a chronic condition outlined in the study. Understanding hypertension as a disease is fundamental to exploring its impact on health-related quality of life and guiding effective treatment strategies to manage symptoms and prevent complications.
24) Pavani (Pāvanī, Pāvani, Pavaṉi, Pavāṉi, Pāvaṉi):
'Pavani' denotes one of the authors referenced in the study, contributing to the body of knowledge surrounding hypertensive treatment regimens. Citing various authors helps contextualize findings and draw comparisons with similar studies, enhancing the credibility and relevance of the research.
25) Mud:
'Mood' refers to emotional states that can be affected by hypertension and its treatment. The study highlights how managing physical symptoms of hypertension can improve mental health outcomes, thereby enhancing the overall quality of life for patients dealing with chronic conditions.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Hypertension prescribing patterns and quality of life in a hospital’. Further sources in the context of Science might help you critically compare this page with similair documents:
Lifestyle modification, Methodology, Age-group, Inclusion criteria, Exclusion criteria, Gender distribution, Morbidity and Mortality, Combination therapy, Single drug therapy, Health-related quality of life, Patient consent form, Age distribution, Diuretic, Angiotensin Converting Enzyme inhibitor, Calcium channel blocker, Prescription Pattern, Beta blocker, Angiotensin receptor blocker, Patient demographic.