Gram-negative bacteria and antibiotic resistance in cockroaches, Dhi-Qar.
Journal name: World Journal of Pharmaceutical Research
Original article title: Gram-negative bacteria load and multiple antibiotic resistance (mar) pattern of pathogenic bacteria isolated from cockroaches at haboubi hospital in the province of dhi –qar
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Amany Sh. Jabber, Saad S. Hamim and Sadik Th. Ali, Intidhaar N. Abid
World Journal of Pharmaceutical Research:
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Full text available for: Gram-negative bacteria load and multiple antibiotic resistance (mar) pattern of pathogenic bacteria isolated from cockroaches at haboubi hospital in the province of dhi –qar
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
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Summary of article contents:
Introduction
Cockroaches, particularly Periplaneta americana, are significant vectors for various pathogens, raising public health concerns due to their presence in environments such as hospitals. The research conducted at Haboubi Hospital in the Dhi Qar province focuses on the bacterial load and antibiotic resistance patterns of pathogenic bacteria found on the external surfaces and in the guts of these cockroaches. This study highlights the potential role of cockroaches as carriers of clinically important multi-drug resistant bacteria, which poses a serious risk for nosocomial infections.
Pathogen Reservoir
The investigation identified a total of 152 bacterial isolates, predominantly Gram-negative bacilli, with the highest prevalence being Salmonella spp. and Proteus mirabilis. The external surfaces of cockroaches exhibited a considerably higher bacterial load (94%) compared to their guts (6%). The distribution of these bacteria indicates significant health risks, as the isolated pathogens can lead to serious infections in humans. The study emphasizes that the hospital environment provides a conducive setting for these cockroaches to thrive and act as reservoirs for pathogenic microorganisms.
Antibiotic Resistance Patterns
The study also revealed alarming levels of multiple antibiotic resistance (MAR) among the isolated bacterial strains, with resistance percentages ranging from 33.3% to 100%. Notably, certain bacteria, including Klebsiella pneumoniae, Pseudomonas aeruginosa, and others, displayed remarkably high MAR indices. The antibiotics commonly used in clinical settings have shown a high resistance profile among the isolated bacteria, suggesting that overuse and misuse of these medications in the hospital may contribute to the antibiotic resistance epidemic.
Public Health Implications
The presence of multi-drug resistant pathogens in cockroaches signifies a concerning nexus between vector biology and public health. As these insects can disseminate pathogens within hospital settings, their control is vital to mitigating infection risks associated with nosocomial diseases. Furthermore, the findings have implications for infection control practices in health care facilities, emphasizing the need for effective pest management strategies to reduce the prevalence of cockroaches and the associated pathogens they carry.
Conclusion
The findings from this research underscore the role of cockroaches as carriers of significant drug-resistant pathogens within hospital environments. The high prevalence of multi-drug resistant bacteria presents a critical challenge to public health, necessitating rigorous measures to manage cockroach populations and the pathogens they harbor. Continuous monitoring and further studies are essential to unravel the mechanisms behind antibiotic resistance in these vectors and to implement effective strategies for controlling their impact on human health.
FAQ section (important questions/answers):
What was the focus of the study conducted in Dhi Qar?
The study investigated the bacterial load and antibiotic resistance patterns of pathogenic bacteria isolated from cockroaches in Haboubi Hospital, Dhi Qar.
Which bacterial species were most commonly isolated from cockroaches?
The most commonly isolated bacteria included Salmonella spp. (20) and Proteus mirabilis (19), with Aeromonas hydrophila/coviae/sobria and Raoultella ornithinolytica being the least at 1 each.
What was the resistance pattern observed in the bacterial isolates?
The isolates showed high levels of antibiotic resistance, particularly to PY (79%), AMC (73.6%), and CRO (73%), with Vancomycin being the most effective (93.4%).
What public health risks are associated with cockroaches in hospitals?
Cockroaches can act as vectors for multi-drug resistant pathogens, posing significant risks for the transmission of nosocomial infections within hospital settings.
How were the cockroaches collected for this study?
Eighty cockroaches were collected over six months from Haboubi Hospital and identified using standard taxonomic keys before testing.
What does MAR stand for and why is it important?
MAR stands for Multiple Antibiotic Resistance. It indicates the level of resistance bacteria have developed against multiple antibiotics, which poses serious treatment challenges in healthcare settings.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Gram-negative bacteria and antibiotic resistance in cockroaches, Dhi-Qar.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Antibiotic (Antibacterial):
Antibiotics are medications used to treat bacterial infections. In the study, the resistance of pathogenic bacteria isolated from cockroaches to various antibiotics was analyzed, highlighting the significance of antibiotic misuse and overuse in hospitals. Understanding antibiotic resistance is crucial in controlling the spread of resistant bacteria and ensuring effective treatment options are available.
2) Surface:
The surface refers to the outer layer of the cockroaches where pathogenic bacteria can reside. In this study, bacterial loads were significantly higher on the external surfaces compared to the internal guts, suggesting that cockroaches may act as vectors for transmitting bacteria to hospital environments, increasing public health risks.
3) Study (Studying):
The study investigates the bacterial load and antibiotic resistance patterns in pathogenic bacteria isolated from cockroaches in a hospital setting. It provides empirical data on the prevalence of multi-drug resistant bacteria, emphasizing the role of cockroaches as vectors for nosocomial infections, crucial for public health and infection control practices.
4) Drug:
Drugs, particularly antibiotics, are critical in treating infections but their misuse can lead to resistance. In the context of the study, the overuse and inappropriate prescriptions of antibiotics in hospitals were associated with increased resistance among bacterial isolates, indicating the need for better drug management and stewardship in medical settings.
5) Species:
Species refer to specific groups of organisms that can interbreed. In the study, various bacterial species were isolated from cockroaches, with significant findings regarding their resistance patterns. Understanding the diversity of these bacterial species is essential in assessing their public health impact and developing appropriate control measures.
6) Science (Scientific):
Science is the systematic study of the structure and behavior of the physical and natural world. This study employs scientific methodologies, including microbiological assays and statistical analyses, to understand the relationship between cockroaches, bacterial pathogens, and antibiotic resistance, emphasizing the importance of scientific research in public health.
7) Insect:
Insects, such as cockroaches, are known to be carriers of various pathogens. The study focuses on cockroaches as vectors transmitting antibiotic-resistant bacteria in hospital settings, illustrating the ecological role of insects in the disease transmission process and highlighting the necessity for pest control in hospitals.
8) Transmission:
Transmission refers to the transfer of pathogens from one host to another. In this study, the role of cockroaches in the transmission of antibiotic-resistant bacteria in hospital settings is a central theme, underlining the importance of understanding vectors in controlling the spread of infections and safeguarding public health.
9) Table:
Tables in the context of research summarize data clearly and concisely. In this study, tables were used to present the antibiotic resistance patterns and the frequency of various isolates. This format aids in the visual comparison of data, making it easier to analyze and interpret results effectively.
10) Discussion:
Discussion is a critical part of the research paper where findings are interpreted and implications are explored. In this study, the discussion section provides insights into the significance of the isolated bacteria, their resistance patterns, and the potential health risks posed by the cockroaches in the hospital environment.
11) Developing:
Developing refers to the progression of healthcare challenges, including antibiotic resistance, particularly in low- and middle-income countries. The study highlights the issues faced by healthcare systems in developing regions where such resistance is prevalent due to factors like inadequate regulation of antibiotic use, presenting challenges in treatment efficacy.
12) Container:
In the laboratory context, containers are used to hold samples or solutions for testing. The study uses sterile containers for transporting cockroaches and for isolating bacterial colonies, emphasizing the importance of sterile techniques in microbiological research to prevent contamination and ensure accurate results.
13) Company:
The term company refers to organizations that produce or sell products. In this study, a specific Turkish company is mentioned as the source for the antibiotics used in susceptibility testing, highlighting the commercial aspect of pharmaceutical supplies in research and the ongoing need for effective antibiotics in medical treatment.
14) Nature:
Nature describes the inherent qualities of organisms and their environments. In this study, the nature of cockroaches as scavengers and potential disease carriers is examined, emphasizing their role in the ecosystem and highlighting the interaction between natural organisms and human health in urban settings.
15) Misuse:
Misuse refers to the inappropriate or excessive use of medications, particularly antibiotics. The study points to the consequences of antibiotic misuse in hospitals, contributing to the development of multi-drug resistant bacteria, underlining the critical need for proper antibiotic stewardship programs to curb resistance trends.
16) Glass:
Glass is a common material used to make laboratory equipment like petri dishes and test tubes. In the study, glass containers are utilized for culturing bacterial isolates, demonstrating the importance of quality materials in microbiological research to ensure reliable and reproducible experiment outcomes.
17) House:
House refers to both residential settings and environments where diseases may spread. The study compares findings from hospital cockroaches with those from residential areas, pointing out the habitat's influence on bacterial colonization and the resulting public health challenges related to pest control in both settings.
18) Blood:
Blood is a vital bodily fluid that can harbor pathogens. While not directly measured in this study, bacteria isolated from cockroaches can infect humans and potentially enter the bloodstream, leading to systemic infections. Understanding the role of vectors like cockroaches in bloodborne pathogens is paramount for infection control.
19) Dish (Diś):
A dish, particularly a petri dish, is used in microbiology for growing bacterial cultures. In this study, dishes are utilized for isolating and culturing bacteria from cockroaches, allowing for the observation of bacterial growth and the assessment of antibiotic susceptibility in a controlled environment.
20) Food:
Food refers to substances consumed by living organisms for nourishment. Cockroaches, as scavengers, can come into contact with food sources, posing a risk for contamination. The role of cockroaches in spreading pathogens through food contamination highlights the need for effective pest control measures in food safety practices.
21) Worm:
Worms, as potential parasites, are separate from the bacteria studied, but they represent another facet of the pathogens cockroaches might carry. While the study primarily focuses on bacteria, recognizing the broader category of pathogens, including worms and other parasites, emphasizes the substantial public health risks posed by cockroaches.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Gram-negative bacteria and antibiotic resistance in cockroaches, Dhi-Qar.’. Further sources in the context of Science might help you critically compare this page with similair documents:
Statistical analysis, Significant difference, Public Health Problem, Pathogenic bacteria, Environmental Contamination, Gram negative bacteria, Drug resistant bacteria, Antibiotic resistance, Standard protocol, Sample collection, Microbial load, Total bacterial load, Salmonella spp., Bacterial load, Proteus mirabilis, Klebsiella pneumoniae, Gram-negative bacilli, E. coli, Pathogenic microorganism, Biochemical test, Hospital Environment, Bacterial isolate, Antibiotic susceptibility testing, Extended Spectrum Beta-Lactamase, Nosocomial infection, Faecal-oral route, Antibiotic susceptibility pattern, Hospital acquired infection, Multiple Antibiotic Resistance, External surface, Neonatal unit, Antimicrobial surveillance program.