Antioxidant activity of methanolic extract of Acorus calamus L.

| Posted in: Science

Journal name: World Journal of Pharmaceutical Research
Original article title: Antioxidant activity of methanolic extract of leaves and rhizomes of acorus calamus l.
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
This page presents a generated summary with additional references; See source (below) for actual content.

Original source:

This page is merely a summary which is automatically generated hence you should visit the source to read the original article which includes the author, publication date, notes and references.

Author:

Nameirakpam Nirjanta Devi, Huirem Reena Devi, Satyavama D Asem, IshworaniChongtham, Koijam Solenia Chanu


World Journal of Pharmaceutical Research:

(An ISO 9001:2015 Certified International Journal)

Full text available for: Antioxidant activity of methanolic extract of leaves and rhizomes of acorus calamus l.

Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research

Copyright (license): WJPR: All rights reserved


Download the PDF file of the original publication


Summary of article contents:

1) Introduction

The study undertaken by Nameirakpam et al. focuses on investigating the antioxidant activity of methanolic extracts derived from the leaves and rhizomes of Acorus calamus Linn., commonly known as Sweet Flag or Calamus. This semi-aquatic perennial herb is native to eastern countries and has traditionally been used for medicinal purposes in various Indian cultures. The extracts were examined for their ability to scavenge free radicals, utilizing the DPPH (2, 2 diphenyl-1-picrylhydrazyl) method. The findings highlighted significant antioxidant properties, particularly in the rhizomes, revealing their potential as a natural source of antioxidants.

2) Antioxidant Activity and Free Radical Scavenging

The results demonstrated that both the leaf and rhizome extracts of Acorus calamus exhibited free radical scavenging activities, with the rhizome extract showing a remarkable scavenging rate of 95% compared to 68% for the leaf extract. This highlights the potential of the rhizomes as a strong source of antioxidants, which are crucial in combating oxidative stress caused by reactive oxygen species (ROS) in the body. The effective reduction of DPPH, a stable free radical, showcases the ability of these plant extracts to neutralize free radicals, offering a promising avenue for preventive health measures against various degenerative diseases.

3) Total Phenolic Content

The study also measured the total phenolic content present in the methanolic extracts, which is a key factor contributing to antioxidant activity. The findings indicated that the leaf extract contained 17.1±0.04 mg gallic acid equivalent (GAE) per gram of extract, while the rhizome extract contained a slightly higher 17.3±0.88 mg GAE per gram. These results suggest a strong correlation between the total phenolic content and the observed antioxidant activity, emphasizing the importance of phenolic compounds as effective scavengers of free radicals.

4) Traditional Medicinal Uses

ACorus calamus has a long history of medicinal use, attributed to its properties such as anti-spasmodic, carminative, anthelmintic, and various other therapeutic applications. Traditionally, it has been used in treating ailments such as epilepsy, chronic diarrhea, and bronchial catarrh. The plant's diverse biological activities go beyond antioxidant properties, including antimicrobial and insecticidal effects. The exploration of its medicinal attributes underscores the relevance of Acorus calamus in traditional herbal medicine and contemporary natural product research.

5) Conclusion

The findings from this study highlight the significant antioxidant capacity of methanolic extracts from Acorus calamus, with strong free radical scavenging abilities linked to its phenolic content. The potential health benefits of this plant are promising, positioning it as a valuable resource for natural antioxidants in pharmacological applications. Further research into the phytochemical constituents of Acorus calamus could unveil additional therapeutic potentials and reinforce its use in traditional medicine, supporting the practice of utilizing natural products for health and wellness.

FAQ section (important questions/answers):

What is the objective of the study on Acorus calamus?

The study aimed to investigate the antioxidant activity and total phenolic content of methanolic extracts from the leaves and rhizomes of Acorus calamus using the DPPH method.

How were the extracts of Acorus calamus prepared?

The leaves and rhizomes were collected, dried, ground, and extracted using methanol via Soxhlet extraction for 96 hours before concentration by evaporation.

What were the antioxidant activity results of the extracts?

The methanolic extracts showed DPPH scavenging activity of 68% for leaves and 95% for rhizomes, indicating stronger antioxidant properties in the rhizome extract.

What is the total phenolic content in the extracts?

The total phenolic content was determined to be 17.1±0.04 mg and 17.3±0.88 mg gallic acid equivalent per gram of extract for leaves and rhizomes, respectively.

What medicinal properties are attributed to Acorus calamus?

Acorus calamus has been used traditionally for anti-spasmodic, carminative, and anthelmintic purposes, as well as in treating various ailments like epilepsy and diarrhea.

How does the DPPH method assess antioxidant activity?

The DPPH method evaluates antioxidant capacity by measuring the reduction of the stable free radical DPPH, which changes color from violet to yellow in the presence of antioxidants.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Antioxidant activity of methanolic extract of Acorus calamus L.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Activity:
Activity refers to the capability of a substance or extract, such as those derived from plants, to elicit a biological effect. In the context of Acorus calamus, the text discusses the antioxidant activity, particularly its ability to scavenge free radicals, which is crucial in understanding health benefits and therapeutic potentials.

2) Acorus calamus:
Acorus calamus, commonly known as Sweet Flag, is a semi-aquatic perennial herb belonging to the family Araceae. The plant is notable for its aromatic leaves and rhizomes, which have been utilized traditionally for various medicinal purposes. Its antioxidant properties are key components in evaluating its health benefits.

3) India:
India is the geographic region where Acorus calamus is indigenous. The plant is found commonly in marshy areas across different states, highlighting its relevance in traditional medicine practices in India. The cultural significance and the diverse uses of the plant in Indian folk medicine are emphasized.

4) Study (Studying):
The study referenced in the text aims to investigate the antioxidant activity and total phenolic content of Acorus calamus extracts. This type of research is essential in the field of pharmacognosy to validate traditional claims and uncover potential applications in preventing oxidative stress-related diseases.

5) Devi (Devī):
Devi here refers to one of the authors of the study, Nameirakpam Nirjanta Devi. Author names are crucial in academic publications to attribute scientific contributions, ensuring proper recognition of researchers’ efforts and allowing readers to refer back to original contributors for more information.

6) Species:
Species denotes the classification of organisms in biology. Acorus calamus is a specific species within the family Araceae. Understanding the specific characteristics and classifications of species helps in biodiversity studies, conservation efforts, and recognizing their ecological significance and potential medicinal uses.

7) Disease:
Disease signifies the biological condition that results from various factors, including oxidative stress caused by reactive oxygen species. Medicinal plants like Acorus calamus offer antioxidants that may combat diseases linked to oxidative damage, making the study of such plants significant for public health and disease prevention.

8) Science (Scientific):
Science represents the systematic study of the natural world, including disciplines such as botany and pharmacology. The research conducted on Acorus calamus exemplifies the scientific approach to exploring natural substances, determining their properties, and validating traditional knowledge through empirical investigation.

9) Life:
Life pertains to the existence and biological processes of living organisms. In this context, the study of Acorus calamus emphasizes the importance of natural products in enhancing the quality of life by potentially preventing or treating diseases and supporting healthy cellular functions.

10) Human body:
The human body is the biological system that can be affected by oxidative stress and diseases. The relevance of antioxidant compounds like those derived from Acorus calamus in protecting the human body from damage caused by free radicals is a significant area of research in health sciences.

11) Antibiotic (Antibacterial):
Antibacterial refers to the capability of certain substances to inhibit bacterial growth. The text implies that Acorus calamus has medicinal properties beyond antioxidant activity, including potential antibacterial effects, making it a valuable candidate for treating infections and diseases caused by pathogenic microbes.

12) Phytochemical:
Phytochemical refers to the bioactive compounds found in plants that contribute to their medicinal properties. The study of Acorus calamus aims to identify phytochemicals responsible for its antioxidant activity, aiding in the development of natural therapies and enhancing our understanding of plant-based treatments.

13) Sweet flag:
Sweet Flag is a common name for Acorus calamus. This name reflects the plant's aromatic qualities and traditional use in herbal medicine. Understanding the common names of plants aids in their identification and enhances communication among herbalists, researchers, and practitioners.

14) Discussion:
Discussion in scientific research refers to the section where findings are interpreted, contextualized, and related to existing literature. The findings related to Acorus calamus’s antioxidant activity would offer insights into implications for health benefits, contributing to a broader understanding of its biological significance.

15) Karnataka (Karṇāṭaka):
Karnataka is one of the states in India where Acorus calamus can be found. Regional knowledge about native plants and their uses enriches traditional medicine practices. Understanding local biodiversity helps in conservation efforts and enhances appreciation for indigenous plant species with medicinal properties.

16) Substance:
Substance refers to the specific chemical compositions derived from plant materials, such as the extracts from Acorus calamus. The chemical characteristics of these substances are important for assessing their medicinal value and biological activities, allowing health practitioners to utilize them effectively.

17) Medicine:
Medicine signifies the science and practice of diagnosing, treating, and preventing diseases. The study of Acorus calamus contributes to medicinal knowledge by exploring its therapeutic properties, which may lead to effective treatments derived from traditional herbal practices and improved health outcomes.

18) Mountain:
Mountain may refer to the higher altitudes where Acorus calamus can thrive in India. Habitat diversity, including mountainous regions, influences the availability and characteristics of medicinal plants, presenting varying ecological conditions important for the study and conservation of such species.

19) Epilepsy:
Epilepsy is a neurological disorder characterized by recurrent seizures. The text mentions that extracts from Acorus calamus have historically been used to treat neurological conditions, highlighting the importance of exploring such plants for their potential applications in treating epilepsy and other related disorders.

20) Kannada (Kannaḍa):
Kannada is the language spoken in the state of Karnataka, where Acorus calamus is found. Local names and languages provide insights into cultural heritage and traditional uses of plants; they are essential for preserving indigenous knowledge and practices regarding medicinal plants.

21) Kashmir (Kashmīr):
Kashmir is a region in India where Acorus calamus grows naturally. Understanding the geographical distribution of plants is vital for biodiversity assessments and recognizing how different environmental factors can affect the medicinal properties and uses of plant species.

22) Family:
Family in botanical taxonomy refers to a rank used to classify a group of related plants. Acorus calamus is part of the Araceae family, emphasizing the importance of understanding taxonomic relationships in studying a plant's properties and potential uses in medicine.

23) Water:
Water is essential for the growth environment of Acorus calamus, which thrives in damp marshy areas. Its reliance on aquatic conditions illustrates the importance of understanding ecological factors that influence the availability and efficacy of medicinal plants.

24) Hindi (Hiṇḍī, Hiṃdī, Himdi, Hindī):
Hindi is one of the languages spoken in India, and it is mentioned here in relation to the common names of Acorus calamus. Language enriches the cultural narratives around medicinal plants and indicates the diverse uses and recognition of the plant across different regions.

25) Fever:
Fever is a common symptom of various health conditions. The historical uses of Acorus calamus for treating ailments, including fevers, highlight its relevance in traditional medicine and suggest avenues for incorporating such plants into modern therapeutic practices.

26) Tamil (Tamiḻ):
Tamil is a regional language spoken in South India. The mention of Tamil in the context of Acorus calamus underscores the cultural significance and traditional knowledge surrounding the plant, as local languages play a critical role in preserving that heritage and understanding its medicinal use.

27) Naga (Nāga, Nag, Nāgā):
Naga refers to a tribal community in northeast India, where Acorus calamus may be found and used. Ethnobotanical studies that explore the uses of plants by indigenous peoples reveal valuable knowledge and practices that can contribute to sustainable approaches in medicine and agriculture.

28) Vasa (Vāsā, Vāsa, Vasā, Vaśā, Vasha):
Vasa is one of the common names for Acorus calamus in Telugu, a language spoken in India. Recognizing various common names aids in understanding the plant's cultural significance and the traditional practices associated with it across different linguistic and regional contexts.

29) Flag:
Flag relates to the common name 'Sweet Flag' for Acorus calamus, which might derive from the plant's sword-like leaves. This name helps facilitate discussions around the plant within both culinary and medicinal contexts, underscoring its multifaceted roles in traditional and modern practices.

30) Fish:
Fish may pertain to the ecological interactions involving Acorus calamus, or its traditional uses in fishing communities. The plant is highlighted for its multifaceted uses, including potential as fish toxins, suggesting the need to further explore ecological impacts and sustainable usage patterns.

Other Science Concepts:

[back to top]

Discover the significance of concepts within the article: ‘Antioxidant activity of methanolic extract of Acorus calamus L.’. Further sources in the context of Science might help you critically compare this page with similair documents:

Acorus calamus, Traditional medicine, Insecticide, Antioxidant activity, Free radical scavenging, Reactive oxygen species, Cardiovascular disease, Carminative properties, Phenolic content, Total phenolic content, Cancer prevention, Methanolic extract, Degenerative disease, Biological activities, Bioactive compound, Anthelmintic properties, Scented leaves, Antibacterial agent, DPPH method, Traditional folk medicine, Natural antioxidant, Antifungal agent, Phenolic compound, Antioxidant compound, Indian medicinal plant.

Let's grow together!

I humbly request your help to keep doing what I do best: provide the world with unbiased sources, definitions and images. Your donation direclty influences the quality and quantity of knowledge, wisdom and spiritual insight the world is exposed to.

Let's make the world a better place together!

Like what you read? Help to become even better: