Aspergillus niger SSF of pomegranate peels yields bioactive products.
Journal name: World Journal of Pharmaceutical Research
Original article title: Aspergillus niger mediated solid state fermentation (ssf) of pomegranate peels, yields bioactive product having antibacterial, antioxidant, radical scavenging and anti-uv properties
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Harshada Satish Dipnaik Priyanka Shrivastava Salgo Merin Jacob
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Aspergillus niger mediated solid state fermentation (ssf) of pomegranate peels, yields bioactive product having antibacterial, antioxidant, radical scavenging and anti-uv properties
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Copyright (license): WJPR: All rights reserved
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Summary of article contents:
Introduction
Pomegranates (Punica granatum L.) are recognized for their rich source of bioactive compounds, particularly phenolic compounds, which offer numerous health benefits. The study explores the potential applications of pomegranate peels, typically regarded as waste, by employing Solid State Fermentation (SSF) using Aspergillus niger to extract valuable bioactive substances. With increasing demand for antioxidants, anti-UV, and antimicrobial products, utilizing such natural resources is becoming more relevant.
Antibacterial Activity of Pomegranate Peel Extract
The antibacterial properties of methanolic extracts from pomegranate peel were evaluated against various bacterial strains. The extracts exhibited notable efficacy in inhibiting Staphylococcus aureus, Bacillus subtilis, and Pseudomonas aeruginosa, especially after six days of fermentation. When applied to textiles, the extract showed an 86.10% reduction in bacterial load for S. aureus and a 92.60% reduction for Klebsiella pneumoniae, demonstrating its promising application in the textile industry, particularly in establishing antibacterial finishes on fabrics used in healthcare settings.
Antioxidant and Radical Scavenging Potential
The antioxidant capacity of the pomegranate peel extracts was assessed through various assays, with results indicating a significant presence of total phenolic content. A strong correlation between the phenolic compounds and the antioxidant activity was observed, suggesting that these compounds primarily contribute to the peel's ability to scavenge free radicals. The extract showed a remarkable superoxide scavenging ability, indicating its potential application in reducing oxidative stress-related damage in biological systems.
Protection Against UV Radiation
Another pivotal aspect of the study was the anti-UV activity of pomegranate peel extracts. The extract demonstrated protective effects on E. coli exposed to UV radiation, allowing the bacteria to survive significantly longer compared to those treated with a control solution. This suggests that phenolic compounds in the extract could absorb or reflect UV radiation, mitigating its harmful effects on living organisms, thereby highlighting the potential of these extracts in cosmetic and protective formulations.
Conclusion
The findings of the study indicate that Solid State Fermentation of pomegranate peels is an effective method for producing bioactive compounds with significant antibacterial, antioxidant, and anti-UV activities. Such extracted compounds hold promising applications in various industries, including food, textiles, pharmaceuticals, and cosmetics. Future optimization of fermentation parameters could further enhance yields and broaden the commercial applicability of these natural resources.
FAQ section (important questions/answers):
What bioactive compounds are found in pomegranate peels?
Pomegranate peels contain bioactive compounds such as flavonoids, phenolic acids, tannins, and vitamin C, which provide numerous health benefits including antioxidant and antimicrobial properties.
How does Solid State Fermentation (SSF) enhance bioactive extraction?
SSF utilizes microorganisms like Aspergillus niger, which efficiently converts agro-waste like pomegranate peels into valuable bioactive compounds, enhancing extraction yields compared to traditional methods.
What antimicrobial activities were observed in the pomegranate peel extracts?
The methanolic extracts demonstrated significant antimicrobial activity against bacteria such as Staphylococcus aureus and Pseudomonas aeruginosa, illustrating potential applications in food and textile industries.
What antioxidant properties were measured in the study?
The study measured antioxidant activity using the Ferric Reducing Antioxidant Power (FRAP) assay, indicating pomegranate peel extracts effectively scavenged free radicals and demonstrated significant reducing power.
How does pomegranate peel extract protect against UV radiation?
The extract can shield E. coli from UV radiation, allowing survival for prolonged exposure times, indicating its protective and potential therapeutic properties against UV-induced damage.
What are the applications of pomegranate peel extracts?
Pomegranate peel extracts can be utilized across various industries, including food, pharmaceuticals, textiles, and cosmetics, due to their antimicrobial, antioxidant, and anti-UV properties.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Aspergillus niger SSF of pomegranate peels yields bioactive products.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Pomegranate:
Pomegranate, scientifically known as Punica granatum, is a fruit rich in bioactive compounds, particularly phenolic compounds which provide significant health benefits. Its peels serve as a resource for extracting antioxidant, antibacterial, and anti-UV properties, making it relevant in food, textile, cosmetic, and pharmaceutical industries.
2) Activity:
In the context of this research, 'activity' refers to the capabilities exhibited by pomegranate peel extracts, such as antioxidant, antibacterial, and anti-UV activities. Understanding these activities is vital for leveraging bioactive compounds in various applications, from medicine to the textile industry, highlighting its functional benefits.
3) Antibiotic (Antibacterial):
Antibiotics are substances that kill or inhibit the growth of bacteria. While traditionally sourced from fungi and bacteria, pomegranate peel extracts provide a natural alternative with antibiotic-like properties, suggesting a potential for integrating plant-based antimicrobials into therapeutic strategies and reducing reliance on synthetic antibiotics.
4) Punica granatum:
Punica granatum is the scientific name for the pomegranate plant, known for its fruits and significant health benefits associated with its bioactive compounds. This name underscores the importance of botanical classification in research related to its uses in medicine, nutrition, and industrial applications.
5) Phytochemical:
Phytochemicals are naturally occurring compounds in plants, including flavonoids and phenolic acids, that provide health benefits. The study of pomegranate peels reveals a wealth of phytochemicals, which have implications for developing functional foods and therapeutic agents due to their antioxidant, anti-inflammatory, and antimicrobial properties.
6) Science (Scientific):
Scientific relates to the systematic study of natural phenomena based on empirical evidence and observation. The research on pomegranate peels is scientific in nature, underpinning the methodologies applied for extraction and analysis of bioactive compounds, ensuring reliability and credibility of findings.
7) Water:
Water is essential in the extraction processes of phytochemicals from pomegranate peels. It serves as a solvent in various extraction techniques and is crucial for the physiological functions of all living organisms, highlighting the intersection of chemistry, biology, and environmental science in the research.
8) Cancer:
Cancer refers to a group of diseases characterized by uncontrolled cell growth. There is growing interest in the potential of pomegranate-derived compounds in chemoprevention and treatment due to their antioxidant properties, suggesting a role for these natural products in supporting health and preventing chronic diseases.
9) Sugar:
Sugar, or carbohydrates, are critical nutrients found in pomegranate. The peel contains reducing sugars which contribute to the overall phytochemical profile. Understanding the carbohydrate content can help inform nutritional assessments and the development of functional foods that align with dietary needs.
10) Flavonoid:
Flavonoids are a class of phytochemicals found in pomegranate, contributing to its antioxidant and anti-inflammatory effects. Their presence emphasizes the fruit's health benefits, particularly in combating oxidative stress, thus positioning pomegranate as a functional food in disease prevention and overall health promotion.
11) Cynodon dactylon:
Cynodon dactylon, commonly known as Bermuda grass, is a plant with recognized medicinal properties. The mention of this grass in conjunction with pomegranate highlights ongoing research into various plants, expanding the scope of phytotherapy and potential synergistic effects observed through natural remedies.
12) Pharmacological:
Pharmacological pertains to the study of the effects and mechanisms of naturally occurring compounds in organisms, such as those found in pomegranate. This relevance guides research in drug development, emphasizing the importance of isolating and utilizing bioactive compounds for therapeutic applications.
13) Accumulation (Accumulating, Accumulate):
Accumulating describes the ongoing process of gathering or concentrating compounds in a particular tissue or environment. In the context of pomegranate, understanding how phytochemicals accumulate allows researchers to optimize extraction methods and explore uses in nutrition and pharmacology.
14) Agriculture:
Agriculture is the practice of cultivating plants and livestock. Research into pomegranate peels underscores sustainable agricultural practices by transforming waste into valuable bioactive products, promoting environmentally-friendly practices while enhancing economic viability for farmers and industries reliant on agricultural by-products.
15) Discussion:
Discussion pertains to the analytical consideration of results obtained within the study. It integrates findings, proposes implications, and suggests future research paths, providing a comprehensive evaluation of the significance of pomegranate peel extracts in health and industrial applications.
16) Toxicology:
Toxicology is the study of the adverse effects of substances on living organisms. Understanding the toxicological profiles of bioactive compounds in pomegranate is essential for assessing safety, guiding regulatory compliance, and ensuring that natural products can be safely used in various applications.
17) Ratnamala (Ratnamālā, Ratnamāla, Ratna-mala):
Ratnamala is likely a reference to a contributor or researcher involved in studies related to pomegranate or related subjects. Highlighting specific individuals ensures acknowledgment of contributions within the scientific community, emphasizing collaboration in research endeavors for advancing knowledge.
18) Fenugreek:
Fenugreek is another medicinal plant known for its diverse phytochemical profile. Mentioning fenugreek alongside pomegranate can suggest comparative studies between different plants’ bioactive compounds, exploring potential synergistic benefits and expanding the understanding of their applications in medicine and nutrition.
19) Inference:
Inference refers to the conclusions drawn from data analysis. In this study, inferences about the health benefits of pomegranate peel extracts guide recommendations for further research and practical applications, positioning them as valuable for health and wellness sectors.
20) Toxicity:
Toxicity is the degree to which a substance can harm organisms. Evaluating the toxicity of pomegranate extracts is essential for safety assessments, ensuring that bioactive compounds can be used effectively without adverse effects, thereby enhancing their applicability in health and food industries.
21) Medicine:
Medicine encompasses the science and practice of diagnosing, treating, and preventing illness. The bioactive compounds found in pomegranate have promising roles in medicinal applications, paving the way for their integration into therapeutic regimes and natural remedies.
22) Krishna (Kṛṣṇā, Kṛṣṇa):
Krishna might refer to a researcher contributing to studies in pomegranate or other phytochemical research pursuits. Recognizing individual contributions is vital for academic integrity, emphasizing the collaborative and multifaceted nature of scientific research in developing health-promoting products.
23) Gelatin:
Gelatin, a derived protein, is typically used in food and pharmaceutical formulations. Mentioning gelatin in relation to pomegranate brings attention to cross-disciplinary research exploring how natural extracts can augment or replace synthetic components in food production and health supplements.
24) Priya (Priyā):
Priya could denote a researcher or contributor involved in the project or study of pomegranate. Individual recognition is crucial for scholarly communication and reflects the collective effort necessary to advance understanding in the field of natural products research.
25) Avila (Āvila, Avilā):
Avila may refer to a researcher or contributor related to studies of pomegranate or similar subjects. Acknowledging contributors is essential in academic and scientific discourse, fostering collaboration and crediting those advancing knowledge in the field.
26) Prana (Prāṇā, Prāṇa, Praṇa, Prāṇ, Pran):
Prana signifies vital energy in some contexts, possibly reflecting an aspect of the health benefits derived from natural compounds in pomegranate. This term may be used metaphorically to emphasize the holistic wellness approach promoted by natural products like pomegranate extracts.
27) Hima (Himā):
Hima could refer to a scientist or contributor involved in the research or studies of pomegranate peels. Highlighting contributors underscores the collaborative nature of scientific inquiry and the shared knowledge economy that is essential for progress in health and biotechnology.
28) Rubu:
Rubu could denote a researcher or contributor connected to pomegranate research or related fields. Recognizing authors and contributors helps foster community among scholars and emphasizes the collaborative effort crucial for advancing knowledge and innovation.
29) Mena (Menā, Meṇa, Mēṉa, Mēṉā):
Mena may refer to a researcher or contributor to phytochemical studies related to pomegranate. Acknowledging contributions is vital in the scientific ecosystem, signifying collaborative work and shared goals in enhancing understanding of natural products and their applications.
30) Soya (Sōya):
Soya, or soybean, is a commonly cultivated agro-product known for its protein content and health benefits. Its mention alongside pomegranate suggests an exploration of diverse plant-based sources of bioactive compounds, fostering cross-research into functional foods and sustainable agriculture.
31) Shana (Śaṇa, Śana, Sāṇa, Saṇa, Sanā, Sana, Śānā, Saṅa):
Sana could refer to a contributor in the study relating to pomegranate or comparable research efforts. Recognizing individuals who contribute to scientific research is essential for building collaborative networks and enhancing motivations toward advancing scientific inquiry.
32) Meat:
Meat refers to animal flesh consumed as food. Mentioning meat in conjunction with antibacterial pomegranate research signifies investigations into natural preservatives or antimicrobial agents that can enhance food safety and extend the shelf life of meat products, promoting health.
33) Hand:
Hand might metaphorically suggest the role of human intervention in the research process or the practical applications of findings in fieldwork, thus emphasizing the importance of active participation in scientific endeavors and real-world applications of research outcomes.
34) Sour:
Sour describes a taste profile often associated with the natural flavor of pomegranate and other fruits. This term may be included in sensory evaluations of fruit extracts, highlighting the sensory aspects of natural products and their acceptance in food formulations.
35) Salt (Salty):
Salt, primarily sodium chloride, is used for flavoring and preserving food. Its inclusion in research may relate to the interaction of salt with bioactive compounds from pomegranate, exploring how it affects preservation procedures or the sensory characteristics of food products.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Aspergillus niger SSF of pomegranate peels yields bioactive products.’. Further sources in the context of Science might help you critically compare this page with similair documents:
Punica granatum, Pomegranate juice, Phytochemical, Fermentation process, Antibacterial activity, Antioxidant activity, Antimicrobial activity, Zone of inhibition, Anti-microbial activity, Antioxidant capacity, Total phenolic content, In vitro antioxidant activity, Antioxidant potential, Polyphenols, Methanolic extract, Correlation coefficient, Aspergillus niger, Bacterial load reduction, Bacterial load, Scavenging activity, Cancer chemoprevention, Bioactive compound, Gram positive, Gram negative, Super fruit, FTIR Analysis, Industrial use, S. aureus, P. aeruginosa, Polyphenol oxidase, Radical scavenging, UV Spectrophotometer, Total Phenolic Content (TPC), Superoxide scavenging activity, Antimicrobial test, UV exposure, Phenolic compound, Ellagic Acid, Functional group, Foam test, Organic nature.