Antibacterial Effects of Bee Products in Malaysia: A Review

| Posted in: Science

Journal name: The Malaysian Journal of Medical Sciences
Original article title: Antibacterial Effects of Various Types of Bee Products in Malaysia: A Systematic Review
The Malaysian Journal of Medical Sciences (MJMS) is a peer-reviewed, open-access journal published online at least six times a year. It covers all aspects of medical sciences and prioritizes high-quality research.
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Original source:

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Author:

Nur Aliah Mohamad, Alaa’ Fahed Al-Emerieen, Ahmad Adebayo Irekeola, Rafidah Hanim Shueb


The Malaysian Journal of Medical Sciences:

(A peer-reviewed, open-access journal)

Full text available for: Antibacterial Effects of Various Types of Bee Products in Malaysia: A Systematic Review

Year: 2024 | Doi: 10.21315/mjms2024.31.3.3

Copyright (license): CC BY 4.0


Download the PDF file of the original publication


Summary of article contents:

Introduction

Antibiotic resistance is a growing concern in the treatment of bacterial infections, pushing researchers to explore alternative antibacterial agents, particularly from natural sources. This systematic review examines the antibacterial properties of various Malaysian bee products, including honey, propolis, and bee bread. Utilizing databases such as PubMed and Scopus, the study compiles findings from 32 selected articles focusing on the efficacy of these natural products against both Gram-positive and Gram-negative bacteria. The review underscores the potential of bee products as viable alternatives to conventional antibiotics.

The Antibacterial Potential of Honey

Among the bee products, honey, particularly the Malaysian varieties such as Kelulut and Tualang honey, exhibits promising antibacterial activity. Studies report that honey's efficacy is influenced by factors such as its low pH, low moisture content, and the presence of bioactive compounds including hydrogen peroxide and phenolic acids. For instance, Kelulut honey showed significant inhibitory effects on various pathogenic bacteria, often at lower concentrations than other types of honey. This makes it particularly noteworthy in the context of antibiotic resistance, suggesting that honey can be an effective antimicrobial agent without the drawbacks associated with traditional antibiotics.

Conclusion

The findings from this review highlight the significant antibacterial properties of Malaysian bee products, particularly honey, which presents a natural alternative to combat antibiotic-resistant bacteria. The various physical and chemical characteristics that contribute to honey's antibacterial effects underscore the need for further research to fully understand its mechanisms and applications. Future studies could expand on these insights and explore the potential for integrating bee products into conventional treatment regimens, providing a holistic approach to managing bacterial infections.

FAQ section (important questions/answers):

What are the main antibacterial properties of Malaysian bee products?

Malaysian bee products, including honey, propolis, and bee bread, exhibit significant antibacterial activity against various Gram-positive and Gram-negative bacteria, making them promising alternatives to conventional antibiotics.

How was the literature search conducted for this study?

A systematic literature search was performed across five databases, using keywords related to bee products and their antibacterial properties. A total of 153 articles were initially identified, with 32 included after applying inclusion and exclusion criteria.

What specific types of honey were reviewed in the study?

The study reviewed various Malaysian honey types, including Kelulut, Tualang, Gelam, Acacia, Pineapple, and Durian honey, with Kelulut honey being the most extensively studied for its antibacterial effects.

What role do bioactive compounds play in bee products?

Bioactive compounds in bee products, such as phenolics and flavonoids, contribute significantly to their antimicrobial properties, aiding in the inhibition of harmful bacteria and supporting health benefits.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Antibacterial Effects of Bee Products in Malaysia: A Review”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Honey:
Honey is a natural sweet substance produced by bees from floral nectar. It has significant antibacterial properties attributed to its composition, which includes hydrogen peroxide and various phenolic compounds. Its medical and therapeutic uses have been documented throughout history, making it valuable in the search for natural antibiotics.

2) Antibiotic (Antibacterial):
An antibiotic is a substance used to inhibit bacterial growth or kill bacteria. The significance of antibiotics is overshadowed by the increasing issue of antibiotic resistance, leading to a resurgence in interest in natural alternatives, like bee products, which may offer effective antibacterial qualities without contributing to resistance.

3) Activity:
Activity denotes the biological effect or action of a compound. In pharmacological studies, evaluating the antibacterial activity of substances like honey is essential for understanding their effectiveness against various pathogens. This concept is central to assessing the therapeutic potential of natural products in treating infections.

4) Aureus:
Staphylococcus aureus, commonly referred to as aureus, is a Gram-positive bacterium responsible for various infections, including skin infections and food poisoning. Its relevance extends to the study of antibiotic resistance, emphasizing the importance of exploring alternative antibacterial agents, like honey, in combating such resistant bacterial strains.

5) Study (Studying):
A study is a systematic investigation aimed at discovering or interpreting facts. In the context of this research, studies on the antibacterial properties of bee products provide critical insights into their efficacy, mechanisms, and potential applications in medicine, contributing to evidence-based practices in healthcare.

6) Table:
In research papers, a table presents data in an organized format, allowing for easy comparison and analysis. Tables serve as tools to summarize complex information, such as antibacterial activity results, which enhance the clarity and accessibility of findings for readers and researchers alike.

7) Trigona (Tri-gona):
Trigona refers to a genus of stingless bees known for producing unique types of honey and propolis. Their honey is celebrated for its distinct flavors and potential health benefits. The study of Trigona honey is significant given its novel properties and applications in the field of natural medicine.

8) Species:
Species refers to a group of organisms that can interbreed and produce fertile offspring. In the context of beekeeping, understanding different honeybee species, like Apis and Trigona, is crucial not only for honey production but also for studying their varying antibacterial characteristics and ecological roles.

9) Phytochemical:
Phytochemicals are bioactive compounds derived from plants that contribute to their medicinal properties. In bee products, phytochemicals help underline the health benefits of honey and propolis, driving research interest in their potential roles in combating infections and disease through natural therapeutic means.

10) Flavonoid:
Flavonoids are a class of phytochemicals with antioxidant and anti-inflammatory properties found in various plants. They contribute to the antibacterial activity observed in bee products, such as honey and propolis, highlighting their importance in natural medicine and food science as functional components in disease prevention.

11) Medicine:
Medicine encompasses the science and practice of diagnosing, treating, and preventing illness. The relevance of bee products in traditional and modern medicine lies in their therapeutic properties, particularly their antibacterial effects, which offer potential alternatives to synthetic drugs in managing infections.

12) Science (Scientific):
Science represents the systematic study of the natural world through observation and experimentation. The research on bee products' antibacterial properties exemplifies this, as it integrates disciplines like microbiology and pharmacology to validate and explore the medicinal uses of these natural substances.

13) Mountain:
Mountain honey typically refers to honey sourced from mountainous regions, often valued for its unique flavor profiles and potential health benefits. The geographical origin influences the floral sources available to bees, subsequently affecting the honey's composition and biological activities.

14) Mandal:
Mandal likely references a researcher or a specific study related to bee products, particularly highlighting their antibacterial activity. This can be significant in the academic context of exploring honey's medicinal properties and its role in enhancing health through natural means.

15) Water:
Water is a critical component in the extraction and preparation of honey and other bee products for testing their antibacterial properties. Understanding how water affects concentration and activity levels is essential when analyzing the effectiveness of these natural substances against pathogens.

16) Tree:
Trees are vital for honey production, as they provide nectar sources for bees. The type of trees and the flowers they yield directly affect the quality, flavor, and health benefits of the honey produced, making them relevant in studies aimed at enhancing natural antibiotic alternatives.

17) Quality:
Quality refers to the standard or degree of excellence of a product. In the context of honey and bee products, quality is determined by factors like purity, composition, and antibacterial efficacy, which are critical for assessing their health benefits and potential therapeutic applications.

18) Ambu:
Ambu may refer to researchers or medical professionals involved in the study of antibacterial activity, particularly in relation to bee products. Their work helps bridge the gap between traditional uses of honey and contemporary medical practices, enhancing the understanding of natural antibiotic sources.

19) Rich (Rch):
Rich indicates a high concentration or abundance of certain compounds. When discussing bee products, especially honey, the richness in bioactive compounds such as antioxidants and phytochemicals is key to explaining their therapeutic potential and effectiveness in combating various pathogens.

20) Life:
Life represents the biological essence that honey and other bee products support. Because of their nutritional and medicinal qualities, these products contribute to human health, functioning as natural remedies and sustaining life through their unique properties.

21) Measurement:
Measurement involves quantifying specific attributes, such as the antibacterial effectiveness of honey or propolis. Accurate measurements, such as MIC and MBC, are crucial for validating the potency of these natural substances, supporting their potential use as alternatives to conventional antibiotics.

22) Disease:
Disease refers to a pathological condition that disrupts normal bodily functions. The antibacterial properties of bee products, especially in relation to infections, underline their potential therapeutic roles in preventing or treating bacterial diseases, making them a focus of ongoing research.

23) Sima (Shima):
Shima could refer to a contributor in a study on bee products or a specific research endeavor. The inclusion of diverse contributors broadens the scope of research on honey's antibacterial properties, fostering collaboration across various disciplines to enhance scientific understanding.

24) Kumar:
Kumar likely represents a researcher whose work focuses on the antimicrobial activity of bee products. His findings and contributions are essential to developing natural therapeutic solutions, promoting the use of honey and bee products in combatting antibiotic-resistant pathogens.

25) Hanka (Hamka):
Hamka might denote a researcher associated with studies involving bee products. Their insights contribute to understanding how traditional remedies can be harnessed in modern medical practices, particularly in addressing growing concerns about antibiotic resistance and the search for effective natural alternatives.

26) Earth:
Earth indicates the natural environment from which honey and other bee products are sourced. The relationship between environmental factors and the properties of these products is significant in assessing their quality and potential health benefits, as they vary based on floral sources and geography.

27) Muda:
Muda refers to a region in Malaysia known for its honey production. Just as with specific flora, the characteristics of honey sourced from Muda may vary, influencing its antibacterial properties and overall effectiveness, making it a relevant subject in the study of natural antibiotics.

28) Food:
Food signifies the essential nutrient-rich substances consumed for sustenance. In terms of honey, its dual role as both a food product and a natural remedy showcases its importance in nutrition and traditional medicine, emphasizing the need for research into its health benefits.

29) Khoo:
Khoo likely refers to a researcher or a contributor in research connected to the antibacterial effects of honey or bee products. Contributions from various individuals in this field significantly enrich the body of knowledge, allowing for a comprehensive understanding of natural antimicrobial agents.

30) Peng:
Peng may refer to a researcher who has investigated the health benefits of honey and bee products. Understanding their work contributes to the broader conversation on natural remedies and health alternatives in a society increasingly challenged by antibiotic resistance.

31) Hand:
Hand often symbolizes human involvement in the process of production or application of honey. In studies, this term may emphasize the human element in harvesting honey and its subsequent use in treating infections, reflecting the blend of nature and human care in medicinal practices.

32) Human body:
The human body is the target of many studies evaluating the health benefits of honey and bee products. Their interactions with microbial infections highlight the importance of natural therapies in supporting the immune system and promoting overall health amidst increasing antibiotic resistance.

33) Performance:
Performance reflects the efficacy of bee products in antibacterial studies. Understanding how different bee products perform in laboratory settings informs potential therapeutic applications and guides future research aimed at integrating these natural substances into mainstream healthcare.

34) Discussion:
Discussion refers to the analytical part of research where findings are interpreted and contextualized. This section is vital for articulating the significance of the results from studies on bee products, bridging the gap between empirical evidence and practical applications in medicine.

35) Substance:
Substance indicates a specific chemical or biological agent. The relevance of various substances, such as those found in honey and propolis, is critical in studies aimed at revealing their potential antibacterial properties and their use as natural alternatives to synthetic antibiotics.

36) Education:
Education promotes awareness and understanding of the therapeutic benefits of natural products like honey. It emphasizes the need for ongoing research and knowledge dissemination to inform healthcare practices and explore the viability of using bee products for health improvement.

37) Mineral:
Minerals are essential nutrients that some bee products, including honey, might contain in trace amounts. The presence of minerals contributes to the overall nutritional profile of honey, enhancing its appeal as a dietary supplement with potential health benefits.

38) Coconut (Cocoanut):
Coconut, while not directly related to honey, might be mentioned in the context of tropical agriculture. Its potential as a nectar source for honey production could influence the flavor profile and medicinal properties of the resulting honey, expanding the study's scope.

39) Killing (Killed):
Killing refers to the antibacterial capability of bee products, primarily honey, in eliminating harmful bacteria. This property is increasingly significant given the rise of antibiotic-resistant strains, highlighting the need for effective natural compounds to combat infections efficiently.

40) Nature:
Nature pertains to the natural origins of honey and bee products. Understanding how these products derive from flowers and the environment emphasizes the importance of conservation and biodiversity in sustaining healthy ecosystems that produce these valuable resources.

41) Misuse:
Misuse relates to the inappropriate or overuse of antibiotics leading to resistance. This highlights the urgent need for alternative treatments, for which natural sources such as honey and propolis may provide effective antibacterial properties, thereby lessening dependency on synthetic antibiotics.

42) Medium:
Medium refers to the environment in which bacteria grow or are tested. In vitro studies of honey’s antibacterial properties depend on appropriate growth mediums to evaluate effectiveness accurately, influencing outcomes and the interpretation of results regarding its antibacterial potential.

43) Queen:
Queen signifies the royal bee crucial to hive function and health. In beekeeping, understanding the role of the queen informs practices to maintain hive productivity and honey production, ultimately affecting the quality and availability of honey and its derived products.

44) Rules:
Rules may refer to the guidelines or standards governing the research conducted on honey and bee products. Following proper research protocols ensures the reliability and validity of findings related to their antibacterial properties and supports evidence-based conclusions.

45) Crop:
Crop relates to the agricultural products that benefit from bees' pollination, including flowers used for honey production. Promoting crop growth through effective pollination highlights the symbiotic relationship between agriculture and bee populations, underscoring the ecological importance of bees in food production.

46) Burning (Burn, Burned, Burnt):
Burn may pertain to the application of honey in wound care for burn treatment due to its antimicrobial properties. The use of honey to soothe and protect burns reflects its role in traditional medicine and modern therapeutic practices.

47) Post:
Post often indicates the presentation or publication of research findings. In the context of studies on honey and its antibacterial effects, sharing results enhances community knowledge, supports scientific discourse, and encourages further exploration into the health benefits of bee products.

Other Science Concepts:

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Discover the significance of concepts within the article: ‘Antibacterial Effects of Bee Products in Malaysia: A Review’. Further sources in the context of Science might help you critically compare this page with similair documents:

Shem, Honey, Antibiotic, Natural product, Therapeutic agent, Traditional medicine, Antibacterial activity, Inclusion and exclusion criteria, Antioxidant properties, Antimicrobial activity, Disc diffusion method, Zone of inhibition, Minimum inhibitory concentration, Literature-Search, Anti-inflammatory effect, Systematic Review, Staphylococcus aureus, Antibacterial properties, Ethanolic extract, Physicochemical properties, Escherichia coli, Pseudomonas aeruginosa, Gram positive bacteria, Gram negative bacteria, Antibiotic resistance, Apis mellifera, Apis cerana, Royal jelly, Agar well diffusion method, Enterococcus faecalis, Propolis, Klebsiella pneumoniae, Bioactive compound, Extraction method, Antifungal effect, Minimum bactericidal concentration, Antibacterial agent, Biofilm formation, Chemical compound, Agar well diffusion, Solvent used, Nanoformulation, Fluorescent microscope, MIC value, Active compound, Propolis extract, MIC, MBC, Electronic database, Biofilm assay, Apis dorsata, Health benefit, Bee venom, Bacterial biofilm, Phytochemical compound, Bee products, Acacia honey, Confocal laser scanning microscopy.

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