Effects of CE-Chirp on ABR Waves in Normal Hearing Infants
Journal name: The Malaysian Journal of Medical Sciences
Original article title: Investigating the Effects of Level-Specific CE-Chirp on Auditory Brainstem Response Waves in Normal Hearing Infants
The Malaysian Journal of Medical Sciences (MJMS) is a peer-reviewed, open-access journal published online at least six times a year. It covers all aspects of medical sciences and prioritizes high-quality research.
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Norashikin Chahed, Ahmad Aidil Arafat Dzulkarnain, Saiful Adli Jamaluddin
The Malaysian Journal of Medical Sciences:
(A peer-reviewed, open-access journal)
Full text available for: Investigating the Effects of Level-Specific CE-Chirp on Auditory Brainstem Response Waves in Normal Hearing Infants
Year: 2024 | Doi: 10.21315/mjms2024.31.2.7
Copyright (license): CC BY 4.0
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Summary of article contents:
Introduction
Auditory brainstem response (ABR) testing is a crucial tool for evaluating auditory function, particularly in infants. Traditional stimuli such as Clicks and tone bursts have been used for years until the introduction of the level-specific CE-Chirp (LS CE-Chirp). The LS CE-Chirp is designed to enhance neural synchrony at various cochlear partition levels, which could improve ABR waveform resolution compared to standard stimuli. Despite some promising preliminary findings regarding the efficacy of LS CE-Chirp, there are limited comparative studies exploring the differences in ABR outcomes between LS CE-Chirp and Click stimuli, especially in normal-hearing infants. This study aims to bridge that gap by comparing the ABR results elicited by these two stimuli.
Enhanced Amplitude Response
One key finding of the study is that the ABR amplitudes for waves I and V elicited by LS CE-Chirp were significantly larger than those produced by the Click stimulus at a supra-threshold level of 70 dBnHL. This increase in amplitude suggests that LS CE-Chirp enhances the synchrony of neural responses across the cochlea, likely due to its innovative design that starts with low-frequency sounds before progressing to higher frequencies. This method improves the overall neural firing synchrony, resulting in clearer and more detectable ABR waveforms. In contrast, wave III amplitudes showed no significant differences between the two stimuli. The notable increase in amplitude and the effectiveness of LS CE-Chirp in eliciting larger ABR responses could make it a more reliable choice for auditory threshold estimation in infants.
Conclusion
In conclusion, the study demonstrates that LS CE-Chirp is a promising advancement in auditory threshold testing for normal-hearing infants, offering significantly larger ABR amplitudes compared to traditional Click stimuli. This finding implies that LS CE-Chirp could lead to more accurate assessments of auditory function in newborns and infants, enhancing early detection of potential hearing impairments. However, these conclusions are currently limited to normal-hearing infants under the conditions of this study. Future research should investigate the applicability of these results to hearing-impaired infants and different populations to further validate the efficacy of LS CE-Chirp in clinical settings.
FAQ section (important questions/answers):
What is the purpose of comparing LS CE-Chirp and Click stimuli?
The study aims to compare auditory brainstem responses (ABR) elicited by level-specific CE-Chirp (LS CE-Chirp) and Click stimuli, assessing differences in waveform amplitude and latency to determine which provides better neural synchrony in normal-hearing infants.
What were the participant criteria in this study?
Sixty-seven normal-hearing infants under seven months old participated, with a mean age of 3.75 months. Infants were selected based on normal DPOAE or AABR screenings, no family history of hearing loss, and intact ear structures.
What were the key findings regarding ABR waveforms?
The study found that ABR waves I and V elicited by LS CE-Chirp had significantly larger amplitudes than those from Click stimuli, indicating LS CE-Chirp’s effectiveness in eliciting better neural responses in normal-hearing infants.
How do LS CE-Chirp and Click stimuli differ in latency?
The absolute latencies of waves I, III, and V were similar between both stimuli types at high-intensity levels, suggesting that the auditory system efficiently adjusts the timing of neural responses regardless of the stimulus used.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Effects of CE-Chirp on ABR Waves in Normal Hearing Infants”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Table:
In the context of research, a table organizes data, presenting it systematically for analysis and comparison. It allows readers to quickly understand patterns, statistics, and important results, such as those connected with auditory brainstem responses (ABR). Tables enable effective summarization and highlighting of key findings from experiments, supporting data-driven conclusions.
2) Study (Studying):
A study refers to a systematic investigation necessitating the collection and analysis of data to uncover new insights or confirm existing theories. In this context, it involves comparing auditory brainstem response (ABR) between different stimuli such as Click and LS CE-Chirp in infants, contributing to audiology and hearing research.
3) Post:
In academic discussions, 'post' often refers to posting data, findings, or results online, allowing peer review or public dissemination. This includes sharing study outcomes on platforms or journals. Such posts enhance visibility, encourage collaborative inquiries, and may influence future research directions or practices involved in auditory testing methods.
4) Rules:
Rules in research design dictate procedures, methodologies, and ethical guidelines researchers must follow to ensure studies are valid and reliable. These could encompass statistical methods employed for analysis, ensuring data integrity, or norms around participant consent, particularly crucial in studies involving infants and auditory brain assessments.
5) Firing:
Firing typically describes the action of neurons activating and sending signals in response to stimuli. In ABR studies, synchronized neuronal firing can enhance response amplitudes. The understanding of neural firing patterns is critical when evaluating the efficacy of auditory stimuli like Click or LS CE-Chirp in producing clear brainstem responses.
6) Reliability:
Reliability refers to the consistency of a measurement tool or a test across different conditions or times. In auditory brainstem response (ABR) studies, establishing reliability is essential, as it indicates that results are reproducible and accurate, allowing for trust in findings related to hearing thresholds and neural activity.
7) Education:
Education encompasses the process of imparting knowledge or skills, particularly within a scientific context. For audiology professionals, ongoing education about auditory testing tools, interpretations of ABR data, and emerging methodologies like the LS CE-Chirp is vital for effective clinical practice and advancing understanding of auditory processing in various populations.
8) Medium:
Medium can refer to the method or material through which research occurs, such as the type of auditory stimulus used in ABR testing. It may also pertain to the medium of communication for research dissemination, impacting how findings reach audiences in the healthcare community, influencing practice and study design.
9) Indian:
Indian may reference cultural or ethnic aspects related to a specific population involved in the research—particularly in the context of this auditory study concerning infants. It can also denote the geographical location of study subjects, influencing auditory response characteristics due to genetic or environmental factors pertinent to hearing and health.
10) Chang:
Chang may refer to a researcher or author contributing to studies within the context of auditory brainstem responses or related fields. Their findings and methodologies can provide additional context on the effectiveness of LS CE-Chirp versus Click stimuli, helping expand the scientific knowledge of auditory processing in infants.
11) Birth:
Birth is significant in the study of auditory responses, marking the onset of sensory and cognitive processing. The early stages of life are crucial for auditory development, influencing how stimuli affect auditory brainstem responses. Understanding how ABR varies in infants helps guide early detection and intervention strategies for hearing issues.
12) Noise:
Noise in a research context refers to extraneous variations in data that can obscure results. In ABR testing, controlling noise levels (for instance, using white noise as a masker) ensures clearer readings of brainstem activity. This is vital for accurate interpretation of results and minimizes false positives in hearing assessments.
13) Jang:
Jang could refer to a contributing researcher in the field of audiology, particularly focused on auditory brainstem studies. Their work may provide valuable insights into methods, data interpretations, or collaborative studies that enhance understanding of how various auditory stimuli elicit responses in different populations, including infants.
14) Discussion:
Discussion in research findings represents an analytical section where results are interpreted in the context of existing literature. This area enables researchers to connect their studies with broader implications, explore limitations, and suggest future research paths, particularly regarding the comparative efficacy of auditory stimuli and what that means for clinical practice.
15) Similarity:
Similarity addresses how closely aligned results from different stimuli or studies are. In ABR research, examining similarities in response patterns triggers insights on neural mechanisms. Identifying similar responses to Click and LS CE-Chirp enhances understanding of infants' auditory processing, helping to define benchmark thresholds for clinical assessments.
16) Knowledge:
Knowledge encapsulates the information derived from research, guiding practical applications in audiology. In auditory studies, knowledge gained from understanding how various stimuli affect ABR is essential for developing effective hearing assessment protocols and for improving diagnostic accuracy in clinical settings, particularly in assessing infants' hearing abilities.
17) Activity:
Activity in the context of auditory studies refers to neuronal responses triggered by stimuli. Measuring the activity level of brainstem responses can provide insight into the auditory system's functionality in infants. Understanding this allows for optimal stimulus choice to elicit clear and reliable auditory brainstem responses for hearing assessment.
18) Relative:
Relative in research often pertains to comparative evaluations between different elements. In the context of auditory stimuli like Click and LS CE-Chirp, analyzing relative amplitudes and latencies becomes crucial for establishing which stimulus yields better auditory brainstem response outcomes, impacting clinical strategies for hearing loss detection.
19) Channel:
Channel can denote the pathway through which auditory stimuli are delivered during ABR testing. It may refer to specific auditory channels in the auditory system or technical channels in the equipment used for testing. Effectively utilizing channels is essential in optimizing sound delivery to achieve accurate ABR measurements.
20) Family:
Family in the context of ABR studies may relate to hereditary patterns of hearing ability or loss which can influence infant auditory processing. Understanding family histories of hearing impairment can help tailor auditory assessments, ensuring early identification and intervention of potential auditory processing issues related to genetic predispositions.
21) Field:
Field represents the academic and clinical domain of study, such as audiology and auditory neuroscience. Within this field, understanding auditory brainstem responses and the impacts of different stimulus types (like Click and LS CE-Chirp) is crucial for developing effective hearing assessments, early detection, and intervention strategies.
22) Sah:
Shah could refer to a contributor in the auditory studies, potentially focusing on the effects of different stimuli on auditory brainstem response outcomes. Their research could provide essential context or comparisons relevant to auditory testing methods, contributing knowledge to improve auditory assessment procedures and outcomes for infants.
Other Health Sciences Concepts:
Discover the significance of concepts within the article: ‘Effects of CE-Chirp on ABR Waves in Normal Hearing Infants’. Further sources in the context of Health Sciences might help you critically compare this page with similair documents:
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