TB Mortality Factors in Manjung District, Perak, Malaysia
Journal name: The Malaysian Journal of Medical Sciences
Original article title: Factors Associated with Tuberculosis Mortality in Manjung District, Perak, Malaysia
The Malaysian Journal of Medical Sciences (MJMS) is a peer-reviewed, open-access journal published online at least six times a year. It covers all aspects of medical sciences and prioritizes high-quality research.
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Original source:
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Asraf Ahmad Qamruddin, Gregory Xavier, Syed Mohammad Zahid
The Malaysian Journal of Medical Sciences:
(A peer-reviewed, open-access journal)
Full text available for: Factors Associated with Tuberculosis Mortality in Manjung District, Perak, Malaysia
Year: 2023 | Doi: 10.21315/mjms2023.30.3.15
Copyright (license): CC BY 4.0
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Summary of article contents:
Introduction
Tuberculosis (TB) remains a significant public health challenge globally, contributing to high morbidity and mortality rates. The disease is caused by Mycobacterium tuberculosis and primarily affects the lungs, though it can impact other regions of the body. In Malaysia, despite being preventable and treatable, TB remains a leading cause of mortality. This study aimed to investigate the epidemiology of TB mortality in the Manjung district of Perak, Malaysia, over the period from 2015 to 2020, identifying socio-demographic and clinical factors that are linked to mortality among TB patients.
Significant Factors Associated with TB Mortality
One of the key findings from the study was the association between age and TB mortality. Patients aged 45 years and older had significantly higher mortality rates, particularly those over 65 years, who had an adjusted odds ratio of 8.67. Additionally, non-Malaysian patients and those notified through government hospitals were at a heightened risk of dying from TB, with adjusted odds ratios of 5.18 and 6.78, respectively. Furthermore, a positive HIV status was a critical determinant, with HIV-positive patients showing over eight times greater odds of mortality compared to those who were HIV-negative. These findings underscore the importance of early detection and optimal management of TB, especially among vulnerable populations such as older adults and those co-infected with HIV.
Conclusion
The study concluded that approximately 16.3% of TB patients in the Manjung district died before completing their treatment, highlighting an urgent need for improved screening and healthcare accessibility. Key risk factors identified, including older age, non-Malaysian citizenship, notification source, and HIV-positive status, point to essential areas for targeted intervention. To effectively reduce TB mortality rates, comprehensive strategies that emphasize early diagnosis, optimized care pathways, and enhanced monitoring of high-risk groups must be implemented within primary healthcare systems.
FAQ section (important questions/answers):
What is the main purpose of the study conducted in Manjung?
The study aimed to describe the epidemiology and factors associated with tuberculosis (TB) mortality in Manjung district, Perak, Malaysia, focusing on cases registered from 2015 to 2020.
What were the significant factors associated with TB mortality?
Significant factors included age (45 years and older), non-Malaysian citizenship, cases notified by government hospitals, and HIV-positive status. These factors indicated a higher risk of TB mortality among patients.
How many TB cases were analyzed in the study?
A total of 742 TB cases were included in the analysis, with 121 cases (16.3%) dying before completing their treatment between 2015 and 2020.
What recommendations were made to reduce TB mortality?
The study recommends early diagnosis, optimized screening, and close monitoring of high-risk groups, specifically targeting individuals aged 45 and older, HIV-positive patients, and non-Malaysians to reduce TB mortality rates.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “TB Mortality Factors in Manjung District, Perak, Malaysia”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Tuberculosis:
Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis. It primarily affects the lungs but can affect other body parts. TB is one of the leading global health concerns and is characterized by cough, fever, and weight loss. Understanding TB is crucial for prevention and treatment, particularly in high-incidence areas.
2) Study (Studying):
A study is a systematic investigation of a particular subject or phenomenon, aiming to establish facts, principles, or generalizations. In this context, the study examines the epidemiology and risk factors associated with tuberculosis mortality in the Manjung district of Malaysia, contributing valuable data for public health strategies and policies.
3) Death:
Death refers to the cessation of all biological functions that sustain a living organism. In medical research, understanding causes of death, particularly in relation to diseases like tuberculosis, is vital to inform healthcare strategies, improve patient outcomes, and reduce mortality rates among vulnerable populations.
4) Table:
In research, a table is a systematic arrangement of data, typically organized in rows and columns for clarity and ease of understanding. Tables are crucial for comparing variables, presenting statistical analyses, and summarizing findings, especially in studies relating to epidemiology and public health.
5) Disease:
A disease is an abnormal condition that negatively affects the structure or function of a part of an organism. For tuberculosis, disease pathology involves the infection with Mycobacterium tuberculosis, leading to various clinical manifestations. Understanding diseases is vital for developing effective treatments and preventive measures.
6) Viru:
There seems to be a typographical error or shorthand for 'virus' or 'viral'. In the context of medical discussions, viruses are infectious agents that can cause diseases. Understanding viral infections alongside bacterial infections like tuberculosis can inform holistic treatment approaches for co-infections.
7) Knowledge:
Knowledge represents the information, understanding, and skills acquired through experience or education. In healthcare, knowledge about diseases, treatment options, and prevention strategies is essential for healthcare professionals and patients to manage health conditions like tuberculosis more effectively and to promote public health.
8) Medicine:
Medicine is the science and practice of diagnosing, treating, and preventing diseases and injuries. It encompasses various disciplines, including pharmacology, surgery, and public health. An understanding of medicine is crucial in addressing diseases like tuberculosis, guiding health policies, and improving patient care.
9) Citizen:
A citizen is a legally recognized subject or national of a state or commonwealth, either native or naturalized. In health studies, citizenship can impact access to healthcare resources and treatment outcomes for diseases like tuberculosis, highlighting the importance of understanding demographic factors in public health.
10) Sharman (Sarma, Sharma, Sarman):
Sharma is likely a reference to the author or researcher involved in studies related to tuberculosis and its mortality. Acknowledging contributions from notable researchers helps to foster academic discourse and collaboration in the pursuit of better understanding and treatment of public health issues.
11) Labour (Labor):
Labour often refers to the workforce engaged in various economic activities. In the context of public health, understanding the demographics of the labor force, particularly migrant workers, is vital, as they may face higher risks of diseases like tuberculosis due to their living conditions and access to healthcare.
12) Akta:
Akta translates to 'Act' in Malay, referencing legal statutes such as the Prevention and Control of Infectious Diseases Act 1988 in Malaysia. Understanding such legal frameworks is important for public health professionals to ensure compliance and enforcement of health policies aimed at controlling diseases like tuberculosis.
13) Dane (Dané):
Dane likely refers to an individual from Denmark. Public health discussions sometimes draw comparisons across countries; understanding international health outcomes, especially involving immigrants and refugees, can provide insights into tuberculosis mortality and help refine strategies to combat health disparities.
14) Pari:
Pari might refer to 'Paris,' a major city in France. Such geographical references often play a role in health discussions as trends and disease prevalence can vary regionally. Investigating urban health dynamics can shed light on public health strategies addressing diseases like tuberculosis in metropolitan areas.
15) Drug:
Drugs refer to substances used to diagnose, cure, treat, or prevent diseases. In tuberculosis treatment, effective antibiotics are critical. Addressing drug resistance in TB is a significant public health challenge. Understanding drug applications and management is vital in combating such infectious diseases.
16) Agriculture:
Agriculture is the practice of cultivating soil, producing crops, and raising animals for food, fiber, and other products. In some communities, agricultural practices can influence health outcomes, including vulnerability to diseases like tuberculosis, which can be exacerbated by nutritional deficiencies experienced by those upholding agricultural livelihoods.
17) Discussion:
Discussion refers to the process of exchanging ideas or negotiating on a topic. In a research context, discussions are vital for interpreting data, providing context, and proposing future research directions. Engaging in discussions on tuberculosis research promotes collective understanding and enhances public health initiatives.
18) Education:
Education is the process of facilitating learning, or the acquisition of knowledge, skills, values, and beliefs. In healthcare, education is crucial for disseminating information about diseases like tuberculosis, preventive measures, and treatment options, empowering individuals to make informed health decisions.
19) Science (Scientific):
Science is a systematic enterprise that builds and organizes knowledge in the form of testable explanations and predictions about the universe. In the study of diseases like tuberculosis, scientific research contributes to understanding disease mechanisms, developing interventions, and shaping public health policies.
20) Chinna:
Chinna may refer to an author or a researcher. Acknowledging the contributions of researchers in the field enhances the credibility of studies and encourages collaboration, which is particularly important in addressing complex public health issues such as tuberculosis and its associated mortality.
21) Cancer:
Cancer is a group of diseases characterized by uncontrolled cell growth. Understanding the complex relationship between cancer and other diseases, such as tuberculosis, is essential for multifaceted public health strategies. Individuals with comorbidities like cancer may have higher mortality rates from infectious diseases like TB.
22) Indian:
Indian typically refers to individuals from India or those of Indian descent. In health research, understanding the demographics of specific ethnic groups can reveal disparities in disease prevalence and treatment outcomes, particularly for diseases like tuberculosis that may affect certain populations disproportionately.
23) Rules:
Rules refer to established guidelines or principles governing conduct. In healthcare, understanding legal and ethical rules surrounding medical practice is vital for addressing public health concerns effectively, including compliance with laws regarding the reporting and treatment of infectious diseases like tuberculosis.
24) Post:
Post may refer to a position or a publication. In research, sharing findings through posts in academic journals is essential for disseminating knowledge about health issues such as tuberculosis. Such contributions can stimulate further research and inform public health policies.
25) Male:
Male describes one of the two primary biological sex distinctions. In health research, demographic factors, including sex, can influence disease prevalence and treatment outcomes. Understanding the epidemiology of tuberculosis based on gender helps refine health interventions and targeted outreach efforts.
Other Health Sciences Concepts:
Discover the significance of concepts within the article: ‘TB Mortality Factors in Manjung District, Perak, Malaysia’. Further sources in the context of Health Sciences might help you critically compare this page with similair documents:
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