Prostate Artery Embolisation Outcomes in Severe BPH Symptoms
Journal name: The Malaysian Journal of Medical Sciences
Original article title: Outcomes of Prostate Artery Embolisation in Patients with Severe Symptoms of Benign Prostate Hyperplasia
The Malaysian Journal of Medical Sciences (MJMS) is a peer-reviewed, open-access journal published online at least six times a year. It covers all aspects of medical sciences and prioritizes high-quality research.
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Original source:
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Rohana ABDUL RAHIM, Goh ENG HONG, Nik Azuan NIK ISMAIL, Rozman ZAKARIA
The Malaysian Journal of Medical Sciences:
(A peer-reviewed, open-access journal)
Full text available for: Outcomes of Prostate Artery Embolisation in Patients with Severe Symptoms of Benign Prostate Hyperplasia
Year: 2021 | Doi: 10.21315/mjms2021.28.6.6
Copyright (license): CC BY 4.0
Download the PDF file of the original publication
Summary of article contents:
Introduction
Benign prostatic hyperplasia (BPH) is a common condition in men, often leading to severe lower urinary tract symptoms (LUTS) that significantly affect quality of life. This condition is particularly prevalent among older men, with many presenting with severe symptoms as assessed by the International Prostate Symptoms Score (IPSS). While traditional treatment options include surgical interventions like transurethral resection of the prostate (TURP), these can be associated with various complications. Prostate artery embolization (PAE) has emerged as a minimally invasive alternative, with the aim of alleviating LUTS by reducing prostate size through targeted embolization of the prostatic arteries.
Efficacy of Prostate Artery Embolization
The study involved ten patients diagnosed with severe LUTS due to BPH, all of whom underwent PAE. The results highlighted a notable reduction in both symptom severity—indicated by a significant decrease in mean IPSS scores—and prostate volume post-procedure. Specifically, patients experienced an average reduction of 12.9 points in their IPSS at follow-up, with a mean prostate volume reduction of nearly 50% as measured by ultrasound. Additionally, the technical success of the procedure was high, with 90% of interventions achieving the desired outcomes without major complications. This indicates that PAE is not only effective in symptom relief but is also a safe procedural alternative to traditional surgeries.
Conclusion
In summary, this study supports the use of prostate artery embolization as a safe and effective treatment for men suffering from severe LUTS associated with benign prostatic hyperplasia. The significant improvements in both symptoms and prostate volume at one, three, and two-to-two-and-a-half-year follow-ups underscore PAE's potential as a primary treatment option. Given the lower risk of complications compared to conventional surgical methods, PAE may become a more widely adopted approach in managing BPH, particularly for patients with severe symptoms who have not responded to medical therapy. Further studies with larger populations are warranted to confirm these findings and assess long-term outcomes.
FAQ section (important questions/answers):
What is benign prostatic hyperplasia (BPH) and its symptoms?
Benign prostatic hyperplasia (BPH) is a condition in men characterized by an enlarged prostate, which leads to lower urinary tract symptoms (LUTS) like urgency, frequent urination, weak urine stream, and possible acute urinary retention.
How does prostate artery embolisation (PAE) help BPH patients?
Prostate artery embolisation (PAE) is a non-surgical procedure that reduces prostate size by blocking the blood supply, which alleviates lower urinary tract symptoms (LUTS) in BPH patients effectively and safely.
What were the results of the PAE study conducted?
In the study, 90% of patients experienced technical success, with significant reductions in International Prostate Symptoms Score (IPSS) and prostate volume, demonstrating that PAE is effective in treating severe LUTS in BPH patients.
Are there any complications associated with PAE?
The study reported no major complications. However, monitoring for potential issues such as pain or other minor side effects is essential. Overall, PAE has shown to be a safe method for BPH treatment.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Prostate Artery Embolisation Outcomes in Severe BPH Symptoms”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Study (Studying):
The term 'Study' refers to the systematic investigation described in the text, focusing on the outcomes of prostate artery embolization (PAE) for treating benign prostatic hyperplasia (BPH). It emphasizes the importance of researching new medical procedures, evaluating their effectiveness, and contributing to evidence-based clinical practices in urology.
2) Post:
The word 'Post' is used to indicate evaluations made after a certain procedure, in this case, referring to follow-up assessments conducted after prostate artery embolization (PAE). These evaluations measure changes in symptoms (IPSS) and prostate volume, helping to determine the efficacy and safety of the treatment over time.
3) Table:
The term 'Table' relates to the organized presentation of data, summarizing results from the study in a clear manner. Tables help convey statistical findings such as patient demographics, symptom scores, and prostate volumes at various follow-up intervals, enabling easier comparison and understanding of key results from the research.
4) Blood:
In this context, 'Blood' refers to the importance of conducting blood tests before the procedure to ensure patient safety. Assessing blood parameters helps in identifying potential health issues that could complicate prostate artery embolization (PAE), contributing to the overall management strategy in treating patients with BPH.
5) Measurement:
The term 'Measurement' relates to the quantification of prostate volume and International Prostate Symptoms Score (IPSS) both pre- and post-procedure. Accurate measurements are crucial for assessing the outcomes of prostate artery embolization (PAE), providing empirical data that validates the procedure's effectiveness in reducing symptoms and prostate size.
6) Quality:
The word 'Quality' often pertains to the assessment of life quality in patients undergoing treatment for benign prostatic hyperplasia (BPH). In this study, it relates to evaluating how improvements in symptoms affect patients' overall well-being and life satisfaction, an important consideration in assessing the success of medical interventions.
7) Disease:
The term 'Disease' refers to benign prostatic hyperplasia (BPH) in this context. BPH is a prevalent condition that causes lower urinary tract symptoms (LUTS) in older men. Understanding this disease underscores the necessity for effective treatment options, such as prostate artery embolization (PAE), aimed at alleviating the symptoms associated with it.
8) Pain:
In the research, 'Pain' is relevant as it addresses post-procedure discomfort experienced by patients. It highlights the management of pain through medications, specifically non-steroidal anti-inflammatory drugs (NSAIDs), reflecting on the importance of patient comfort and safety in medical interventions like prostate artery embolization (PAE).
9) Life:
The term 'Life' emphasizes the broader context of how medical procedures like prostate artery embolization (PAE) affect patients' overall quality of life. The study not only measures clinical outcomes but also focuses on how treatment success impacts daily living and personal well-being for those suffering from BPH.
10) Attending:
The word 'Attending' refers to the involvement of medical professionals, such as doctors and nurses, in the study. It emphasizes the collaborative aspect of healthcare delivery, where various specialists contribute to patient care, from diagnosis to post-procedure follow-up, essential for achieving optimal treatment outcomes.
11) Relative:
The term 'Relative' is significant when discussing patient demographics or conditions in relation to one another. In clinical studies like this one, understanding how various factors relate to treatment outcomes can help clinicians tailor approaches for different patient groups, enhancing the overall effectiveness of prostate artery embolization (PAE).
12) Chang:
The term 'Chang' may refer to a specific researcher or veterinarian mentioned in the citations that could provide insights or findings relevant to the study. Recognizing contributions from other researchers enhances the credibility of the study by situating it within a broader scientific discussion on prostate artery embolization (PAE).
13) Rules:
The word 'Rules' can refer to clinical guidelines or protocols that govern the execution of procedures like prostate artery embolization (PAE). Adhering to established rules ensures that practices remain safe and effective, emphasizing the importance of compliance in medical procedures to achieve the best patient outcomes.
14) Wall:
The term 'Wall' is significant as it can relate to the anatomical structures affected during procedures like prostate artery embolization (PAE). Understanding the anatomical considerations, including how blood supply and tissue health might influence treatment success, is crucial in interventional procedures involving the male reproductive system.
15) Drug:
The term 'Drug' relates to the medication aspect of BPH management. In this study, it highlights the treatments available for symptom relief. A proper understanding of drug therapy is essential for managing patients who are non-responders to initial medical therapies before considering procedures like PAE.
16) Discussion:
The term 'Discussion' refers to the section where study outcomes are analyzed, interpreted, and compared against existing literature. This segment is vital as it provides context, reflects on findings, and examines their implications for clinical practice, helping to validate prostate artery embolization (PAE) as an effective treatment.
17) Teaching:
The word 'Teaching' emphasizes the educational aspect of the study, indicating the knowledge transfer that occurs during the investigation of prostate artery embolization (PAE). It reflects the intention to not only present results but also educate healthcare professionals about advancements in treating benign prostatic hyperplasia (BPH).
18) Nature:
The term 'Nature' can refer to the essential characteristics of benign prostatic hyperplasia (BPH) and its impact on patients. Understanding the natural progression of this condition allows for better intervention strategies, highlighting the need for research that contributes to successful treatment options like prostate artery embolization (PAE).
19) Nani:
The word 'Nani' appears to refer to a key contributor or co-author involved in the study. Recognizing all contributors is essential in academic research for credit and accountability, underlining the collaborative effort needed in clinical studies, particularly when investigating novel treatments for conditions like BPH.
20) Siti (Shiti):
The term 'Siti' likely denotes an individual involved in either the research process or administration within the study context. Recognizing contributors such as this can be important for transparency and acknowledgment of the roles that various team members play in research projects, enhancing collaboration and credibility.
21) Gold (Golden):
The term 'Gold' refers to the 'gold standard' treatment in the context of the study, highlighting transurethral resection of the prostate (TURP) as the conventional approach for BPH. Establishing comparisons with gold standard treatments helps contextualize the efficacy of newer interventions like prostate artery embolization (PAE) within existing frameworks.
22) Male:
The term 'Male' highlights the specific patient demographic under consideration in the study of benign prostatic hyperplasia (BPH). Increasing awareness that this condition predominantly affects older men is essential for targeted healthcare interventions. Understanding demographics aids in tailoring effective treatments like prostate artery embolization (PAE) for impacted individuals.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Prostate Artery Embolisation Outcomes in Severe BPH Symptoms’. Further sources in the context of Science might help you critically compare this page with similair documents:
Pae, Medical treatment, Power of study, Surgical treatment, Conflict of interest, Statistical analysis, Quality of life, Significant reduction, Sexual dysfunction, Benign prostatic hyperplasia, Oral medication, Local anaesthesia, Non steroidal anti inflammatory drug, International Prostate Symptoms Score, Urinary retention, Symptom reduction, Coagulation profile, Lower Urinary Tract Symptoms, Magnetic resonance imaging, Wilcoxon signed-rank test, Interquartile Range, Study Criteria, Surgical therapy, Chronic complication, Acute complications, Blood investigation, Prostate gland, Urinary Incontinence, Renal Profile, Transurethral Resection of the Prostate, Acute urinary retention, Lower Urinary Tract, IPSS score, Case series study, Benign prostatic hypertrophy, Significant statistical difference, Median age, Study Limitation, Research ethics committee, Adverse event, Digital Subtraction Angiography, Medical therapy, Contrast agent, Staff nurses, Urologist, Standard of care, Follow-up data, Surgery department, Nasopharyngeal carcinoma, Computed tomography angiogram, Non-responders, Technical help, Anaesthesia risk, Authors contribution, Radiology department, BPH patients.