Non-Operative Mesotherapy vs. Surgery for Superficial Lipomas

| Posted in: Science

Journal name: The Malaysian Journal of Medical Sciences
Original article title: Comparison of Non-Operative Mesotherapy and Surgery in the Management of Superficial Lipomas
The Malaysian Journal of Medical Sciences (MJMS) is a peer-reviewed, open-access journal published online at least six times a year. It covers all aspects of medical sciences and prioritizes high-quality research.
This page presents a generated summary with additional references; See source (below) for actual content.

Original source:

This page is merely a summary which is automatically generated hence you should visit the source to read the original article which includes the author, publication date, notes and references.

Author:

Kamal Kataria, Meghna Venkatesh, Sunil Chumber, Yashwant Rathore, Anurag Srivastava, Anita Dhar, Piyush Ranjan, Rajni Yadav, Surabhi Vyas, Priyanka Naranje


The Malaysian Journal of Medical Sciences:

(A peer-reviewed, open-access journal)

Full text available for: Comparison of Non-Operative Mesotherapy and Surgery in the Management of Superficial Lipomas

Year: 2021 | Doi: 10.21315/mjms2021.28.1.7

Copyright (license): CC BY 4.0


Download the PDF file of the original publication


Summary of article contents:

Introduction

Lipomas are benign adipocytic tumors that commonly occur in various parts of the body. Although often asymptomatic, they can cause discomfort due to their size or location. The traditional treatment for lipomas is surgical excision, which, while effective, often results in scarring and potential complications. Recently, alternative treatments have emerged, such as mesotherapy, which does not require an incision and boasts better cosmetic outcomes. This study explores the efficacy of mesotherapy versus surgery in treating lipomas, specifically assessing cosmetic results and size reduction.

Efficacy of Mesotherapy

Mesotherapy involves injecting a solution containing phosphatidylcholine and sodium deoxycholate directly into the lipoma, promoting localized fat dissolution. In a randomized controlled trial involving 126 patients, those receiving mesotherapy exhibited a significant mean reduction of 55.86% in lipoma volume compared to traditional surgical methods. Patients reported higher satisfaction with the cosmetic results of mesotherapy, with 63% of participants expressing happiness with their treatment, compared to only 21% in the surgery group. Additionally, the study showed that mesotherapy resulted in fewer complications, mainly mild reactions like rashes, while surgical patients faced issues like infections and hematomas.

Conclusion

The findings indicate that mesotherapy is a viable alternative to surgical excision for treating lipomas, particularly in patients seeking reduced scarring and improved cosmetic results. While surgery remains the standard treatment, mesotherapy demonstrates significant effectiveness in reducing lipoma size with limited side effects. Future studies should focus on standardizing treatment protocols and extending follow-up periods to evaluate long-term outcomes, including the potential for lipoma recurrence.

FAQ section (important questions/answers):

What are lipomas and how are they treated?

Lipomas are benign adipocytic tumors that can be treated through surgical excision. However, surgery may result in scarring and complications, leading to the exploration of alternative treatments such as mesotherapy, which aims for less invasive cosmetic results.

How was the effectiveness of mesotherapy assessed in the study?

In the study, the effectiveness of mesotherapy was evaluated through randomized groups of patients. They monitored changes in lipoma volume, patient satisfaction, and cosmetic outcomes after six sessions of treatment, with follow-up assessments conducted over 12 weeks.

What complications were observed with mesotherapy and surgery?

Mesotherapy caused minor complications such as rashes and mild pain, while surgical complications included infections and hematomas. Most mesotherapy-related issues resolved quickly, indicating it was a safer option for many patients.

What were the main findings of the mesotherapy study?

The study found that mesotherapy significantly reduced lipoma volume with high patient satisfaction and minimal complications. In contrast to the surgical group, more patients expressed happiness with the cosmetic outcomes from mesotherapy.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Non-Operative Mesotherapy vs. Surgery for Superficial Lipomas”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Table:
Table refers to a systematic representation of data in rows and columns, which allows for a clear comparison and analysis of variables and outcomes in a study. In research articles, tables help summarize key findings, such as patient demographics or treatment results, making complex information more accessible and understandable.

2) Study (Studying):
A study is a structured investigation aimed at answering specific research questions or hypotheses. In medical research, this often involves comparing treatments or observing outcomes in a controlled manner. Studies contribute to evidence-based medicine by providing systematic data that can be used to inform clinical practices and policies.

3) Pain:
Pain is a significant subjective experience that patients report following medical treatments. Understanding pain levels is crucial for assessing treatment efficacy and patient satisfaction. In clinical trials, pain is often measured using scales (like VAS) to quantify the discomfort experienced during or after procedures, guiding improvements in care protocols.

4) Swelling:
Swelling is an important clinical observation that can result from various medical interventions, including surgical procedures. In studies on treatment efficacy, monitoring swelling helps evaluate possible side effects and the body's response to therapies. Excessive swelling may indicate complications, thus it is essential for patient assessment and management.

5) Post:
Post generally refers to the period following a particular event or treatment. In clinical contexts, post-treatment assessments measure outcomes such as recovery, complication rates, or symptom improvements. These evaluations are crucial for understanding the effectiveness of interventions and ensuring the best patient care decision-making.

6) Incision:
An incision refers to a surgical cut made in the skin or tissue, important for accessing underlying structures during surgery. The size and technique of incision can significantly impact patient recovery, potential complications, and cosmetic outcomes. Minimizing incision size is often pursued for better aesthetic results in procedures.

7) Rules:
Rules can pertain to the guidelines or protocols established in clinical studies, outlining how to conduct research ethically and systematically. These ensure that studies are valid, repeatable, and that patient safety is prioritized, contributing to reliable data that can influence best practices in medical care.

8) Shand (Sand):
In this context, 'Sand' likely refers to an author's name that contributed to the understanding of lipoma treatments. Citing researchers highlights the collaborative nature of science, as researchers build on each other’s work, creating a broader understanding of treatment methodologies and patient outcomes.

9) Ras (Rash):
A rash is a visible change in skin appearance, often indicating an adverse reaction to treatments like mesotherapy. Identifying and managing rashes is important in clinical practice as they can affect patient comfort and satisfaction. Tracking such side effects helps refine treatment protocols for better outcomes.

10) Gold (Golden):
Gold standard refers to the best or most accepted method used as a benchmark in clinical practice. In the context of lipoma treatment, surgical excision is considered the gold standard. This concept helps in comparing new treatment modalities against the best-known practice to validate their effectiveness.

11) Antibiotic (Antibacterial):
Antibiotics are medications used to treat infections, often administered post-surgery to prevent or manage infection risks. Understanding their role in surgical contexts is crucial for improving patient outcomes and guiding post-operative care. Their use plays a significant part in overall surgical management strategies.

12) Surface:
Surface refers to the external areas of the body or skin being treated or examined. When discussing surgical or treatment procedures, understanding the surface areas affected is vital for planning interventions and measuring outcomes effectively, particularly regarding cosmetic results.

13) Tantri (Tamtri):
Tantri likely refers to one of the researchers or authors involved in the study on lipomas. Recognizing the contributors to research emphasizes the collaborative nature of science and underlines the importance of diverse perspectives for improving healthcare practices and understanding complex medical conditions.

14) Griva:
Griva seems to denote an individual associated with the research findings, similar to Tantri. Recognition of varying contributors to a study promotes a comprehensive understanding of the research background and the collective effort required in medical advancements and treatment methodologies.

15) Cutan:
Cutan relates to the skin and is often used in medical terminology to discuss treatments targeting skin conditions or lesions, such as lipomas. Understanding cutaneous factors is essential for developing effective treatments and ensuring positive patient outcomes across therapeutic interventions.

16) Hand:
Hand refers to the anatomical location where several lipomas may develop. Recognizing specific anatomical sites for conditions allows targeted treatment plans. Understanding the prevalence of lipomas in regions like the hand informs clinicians of potential patterns or risks associated with these benign tumors.

17) Drug:
Drug refers to any substance used for treatment, prevention, or diagnosis of conditions. In the context of mesotherapy for lipomas, understanding the therapeutic agents used (like phosphatidylcholine) is essential for evaluating safety, efficacy, and potential side effects in clinical practices.

18) Burning sensation:
A burning sensation is an important symptom that can indicate irritation or adverse reactions to treatments. Monitoring such sensations during clinical trials helps assess the safety and comfort of patients undergoing a procedure, guiding adjustments to treatment protocols to enhance patient experience.

19) Transformation (Transform, Transforming):
Transformation refers to a change or modification, often discussed in the context of benign lesions like lipomas, which typically do not transform malignantly. Understanding this concept is vital in evaluating treatment methods, as it assures patients regarding the non-threatening nature of these tumors.

20) Surrounding:
Surrounding refers to the tissues and areas adjacent to a lesion being treated. Understanding the surrounding structures is crucial in surgical or therapeutic procedures to prevent damage to vital organs, enhance postoperative care, and ensure optimal recovery with minimal complications.

21) Measurement:
Measurement is a fundamental aspect of clinical research, used to quantify outcomes, assess efficacy, and compare results across treatments. Reliable measurement methods ensure the validity of study conclusions, guiding clinical decision-making and health policy based on solid evidence.

22) Discussion:
Discussion is a critical section in research articles that interprets results, placing findings in the context of existing literature and clinical implications. This section helps readers understand the study's significance, limitations, and areas for future research, fostering knowledge advancement in medical science.

23) Developing:
Developing refers to the process of creating or refining treatments and interventions. In medical research, studying developing trends is essential for discovering improved methodologies, understanding disease mechanisms, and enhancing patient care across various medical disciplines.

24) Bleeding:
Bleeding is a potential complication during or after various medical procedures. Monitoring bleeding is crucial for patient safety, as excessive bleeding can necessitate further medical intervention. Understanding its incidence helps in the evaluation of different treatment methods and their overall safety profiles.

25) Pregnant:
Pregnant individuals are often excluded from clinical studies to ensure the safety of both the mother and fetus. Understanding the implications of including or excluding certain populations is essential for developing ethical research practices and ensuring results are applicable to broader patient demographics.

26) Disease:
Disease encompasses any abnormal condition affecting the body. Understanding the etiology, prevention, and treatment of diseases informs clinical practice and public health strategies, promoting improved outcomes. Knowledge of disease characteristics is vital for the development of effective therapeutic interventions.

27) Coconut (Cocoanut):
Coconut may refer to its use in treatment, such as a topical emollient for skin reactions. Understanding natural remedies like coconut oil enriches patient care discussions, providing options that may complement conventional treatments for skin irritation or other conditions.

28) Burning (Burn, Burned, Burnt):
Burning refers to an uncomfortable sensation that can indicate an adverse reaction to medical treatments. Monitoring for burning sensations helps assess the safety and efficacy of therapies. Managing discomfort during clinical procedures enhances overall patient satisfaction and informs adjustments to treatment protocols.

29) Allergy:
Allergy signifies an individual's hypersensitivity to specific substances, which can complicate treatment strategies. Recognizing the role of allergies in clinical settings is vital for ensuring patient safety and formulating effective interventions while avoiding contraindicated medications or procedures.

30) Nature:
Nature refers to inherent qualities or characteristics of conditions, diseases, or biological phenomena. Understanding the nature of lipomas, in this case, as benign tumors influences treatment approaches and patient expectations, guiding clinicians in managing conditions effectively.

31) Indian:
Indian likely references the specific population studied or the geographical context of the research. Understanding cultural and demographic factors is important for developing appropriate healthcare interventions, ensuring they are tailored to the needs of the local population for better health outcomes.

32) Desire:
Desire expresses a patient's wish or preference regarding treatment options. Understanding patient desires is essential for patient-centered care, guiding discussions around treatment choices, and fostering better healthcare experiences through tailored approaches that respect individual preferences.

33) India:
India denotes the geographical and cultural context within which the study was conducted. Understanding the setting influences the applicability of research findings to different populations, highlighting the importance of local studies in addressing unique regional health concerns and practices.

34) Roman (Roma):
Roman could refer to historical influences on medical practices or treatment methodologies that still impact contemporary healthcare. Understanding historical contexts enriches the appreciation of current medical practices and fosters an understanding of how past discoveries shape modern healthcare.

35) Cina:
China could refer to the historical origins of treatment modalities such as mesotherapy, with practices dating back millennia. Understanding these origins helps contextualize current treatment methodologies, showcasing the rich history of medical advancement and its evolution over time.

36) Miṇi (Mini):
Mini often describes minimally invasive surgical techniques, which aim to reduce recovery time and complications. Understanding the advantages of such techniques supports the evolution of surgical practice towards methods that enhance cosmetic outcomes and patient satisfaction.

37) Beta:
Beta may relate to beta-adrenergic agonists used in various medical treatments. Understanding the pharmacological role of such agents is important for developing effective therapeutic strategies and managing conditions related to metabolic processes and body composition.

38) Fear:
Fear often describes a psychological response that can influence patient decisions regarding treatment. Understanding patient fears is crucial in clinical practice to address concerns effectively, enhance communication, and ensure informed consent in treatment plans.

39) Inci (Imci):
Inch refers to a unit of measurement that can be relevant when discussing dimensions of anatomical structures or tumors. Accurate measurement in inches is important for planning interventions, assessing treatment efficacy, and standardizing protocols in medical practice.

40) Male:
Male typically refers to a gender demographic that can influence disease incidence and treatment response. Understanding gender differences is crucial for developing personalized medicine approaches and ensuring equitable care across diverse populations.

41) Life:
Life signifies the overall health and wellbeing of individuals, crucial in evaluating treatment impacts. Understanding the implications of medical interventions on quality of life guides clinicians in choosing the most appropriate therapies for patients, fostering holistic healthcare.

Other Science Concepts:

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Discover the significance of concepts within the article: ‘Non-Operative Mesotherapy vs. Surgery for Superficial Lipomas’. Further sources in the context of Science might help you critically compare this page with similair documents:

Surgical excision, Complication, Upper limb, Statistical analysis, Group A, Excellent result, Indian population, Significant reduction, Group (b), P Value, Visual analog scale, Hypopigmentation, Surgical Procedure, Cosmetic Outcome, Gold standard treatment, Statistical analyses, Mean age, Patient satisfaction, Subcutaneous injection, Injection Therapy, Surgical Site, Malignant transformation, Surgical site infection, Fine needle aspiration cytology, Soft Tissue Tumour, Phosphatidylcholine, Gold standard, Fine needle aspiration, Active component, Alternative method, Triamcinolone acetonide, Randomised controlled trial, Surgical complication, Lipoma, Sodium deoxycholate, Mean reduction, Mesotherapy, Subcutaneous swellings, 26-gauge needle, Diabetes Obes Metab.

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