TB Treatment Success in TB/HIV Co-Infection in NE Malaysia
Journal name: The Malaysian Journal of Medical Sciences
Original article title: Prevalence and Factors Associated with Tuberculosis Treatment Success among TB/HIV Co-Infection in North-East Malaysia
The Malaysian Journal of Medical Sciences (MJMS) is a peer-reviewed, open-access journal published online at least six times a year. It covers all aspects of medical sciences and prioritizes high-quality research.
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Tengku Mardhiah Tengku Jalal, Sarimah Abdullah, Farhanah Abd Wahab, Sharina Dir, Nyi Nyi Naing
The Malaysian Journal of Medical Sciences:
(A peer-reviewed, open-access journal)
Full text available for: Prevalence and Factors Associated with Tuberculosis Treatment Success among TB/HIV Co-Infection in North-East Malaysia
Year: 2017 | Doi: 10.21315/mjms2017.24.6.9
Copyright (license): CC BY 4.0
Download the PDF file of the original publication
Summary of article contents:
Introduction
Tuberculosis (TB) has been a significant global public health issue since it was recognized by the World Health Assembly in 1991. The emergence of the human immunodeficiency virus (HIV) has exacerbated the TB epidemic, as individuals co-infected with HIV are at a higher risk of developing TB. This study focused on the prevalence of successful TB treatment among patients with TB/HIV co-infection in North-East Malaysia, analyzing various socio-demographic and clinical factors that may influence treatment outcomes. The findings aim to inform better strategies for managing TB in high-risk populations.
Impact of Gender and Tuberculin Test on TB Treatment Success
The study revealed that male patients, who represented a significant majority of the TB/HIV co-infection cases (91.1%), had a treatment success rate of only 27.9%. Notably, male patients were found to be 58% less likely to achieve treatment success compared to female patients. Furthermore, the analysis indicated that a positive tuberculin test result significantly correlated with treatment success, with those testing positive being 2.59 times more likely to have favorable treatment outcomes. These results highlight the importance of focusing on gender-specific factors and the role of tuberculin testing in managing TB treatment among co-infected patients.
Conclusion
The findings underscore critical factors associated with TB treatment success in TB/HIV co-infection cases within Kelantan, Malaysia, emphasizing the roles of gender and tuberculin test results. To improve treatment outcomes, public health initiatives should prioritize increased awareness and targeted interventions for male patients and those with negative tuberculin test results, particularly among the unemployed and drug-addicted populations who exhibit higher risks of treatment failure. This focused approach can lead to more effective early diagnosis and better adherence to TB treatment, ultimately enhancing public health outcomes in this vulnerable group.
FAQ section (important questions/answers):
What was the purpose of the study on TB/HIV co-infection?
The study aimed to determine the prevalence of successful tuberculosis (TB) treatment and factors associated with treatment success among patients co-infected with TB and HIV in North-East Malaysia.
What were the main findings regarding treatment success rates?
Of the 1510 TB/HIV co-infection cases analyzed, 27.9% achieved treatment success, defined as being cured or having completed their TB treatment.
What factors were associated with successful TB treatment?
The study found that male gender and negative tuberculin test results were significantly associated with treatment success among TB/HIV co-infection patients.
What recommendations were made for improving TB treatment outcomes?
The study recommended focusing on female patients and those with negative tuberculin tests to improve adherence and success rates in TB treatment.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “TB Treatment Success in TB/HIV Co-Infection in NE Malaysia”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Tuberculosis:
Tuberculosis (TB) is a highly infectious disease caused by the bacterium Mycobacterium tuberculosis. It primarily affects the lungs but can also impact other parts of the body. Its enduring presence and the dangers posed, especially among vulnerable populations like TB/HIV co-infection cases, highlight the need for focused public health interventions and successful treatment outcomes.
2) Table:
Tables are essential for organizing data in a clear and efficient manner, facilitating comparison and analysis. In research studies, including the one discussed, tables collectively summarize findings such as socio-demographic and clinical characteristics, making complex information accessible and helping to convey results more effectively to readers.
3) Study (Studying):
A study is a systematic investigation or analysis aimed at discovering facts, developing theories, or providing insights. The particular study referenced explores the prevalence of successful tuberculosis treatment and its associated factors among TB/HIV co-infection patients. Such studies inform public health strategies and resource allocation.
4) Male:
Male patients comprise a significant population in TB cases, often experiencing a higher burden of the disease than females. In this context, gender disparities spotlight the particular challenges faced by male patients in treatment compliance and success, underscoring the need for gender-sensitive approaches in TB prevention and management.
5) Drug:
Drug use is a critical factor influencing health outcomes, particularly in the context of TB treatment success. Drug addicts often face barriers to adherence, leading to poorer health outcomes. Understanding their specific challenges can help healthcare systems provide targeted interventions and develop tailored educational programs to enhance treatment compliance.
6) Disease:
Disease encompasses a wide range of health conditions, including infectious diseases like tuberculosis. The study addresses the prevalence of disease among co-infected patients, emphasizing the importance of early diagnosis, treatment adherence, and the multifaceted nature of managing diseases, especially in vulnerable populations like those with HIV.
7) Bharu:
Bharu references 'Kota Bharu,' a significant city in Kelantan, Malaysia. The city serves as an important focal point for TB research due to its unique socio-demographic landscape. Localized studies, like this one, contribute valuable insights into health challenges faced by the population in the region.
8) Kota:
Kota refers to cities or towns in Malay. In this context, it is used to denote Kota Bharu, where the study investigated TB cases. Understanding the urban health dynamics within cities helps public health officials develop targeted interventions catering to the specific needs of urban populations affected by TB.
9) Pur:
Poor adherence to treatment is a significant challenge in combating TB. This term illustrates the relationship between socioeconomic status and health outcomes. The study highlights the association of poor treatment success in certain demographics, necessitating targeted interventions to improve health education and support for underprivileged populations with TB.
10) Rules:
In the medical context, rules can refer to clinical guidelines and established procedures for diagnosis and treatment. The study relies on rules set by health authorities to define treatment success. Adhering to clinical rules ensures that healthcare providers deliver evidence-based practices for optimal patient outcomes.
11) Developing:
Developing refers to countries with emerging economies facing particular health challenges, particularly in managing infectious diseases like TB. These nations often grapple with limited healthcare resources, necessitating tailored healthcare policies and global support to combat TB and improve health outcomes among vulnerable populations.
12) Medicine:
Medicine encompasses the science and practice of diagnosing, treating, and preventing diseases. The study falls within the realm of public health medicine, focusing on tuberculosis and its management within specific populations. Advancements in medicine, including treatment protocols for TB/HIV co-infection patients, significantly impact health outcomes.
13) Mishra (Misra):
Mishra refers to a researcher or author related to tuberculosis studies. The mention indicates engagement with peer-reviewed literature, providing credibility and context to the study's findings. Identifying influential researchers aids readers in tracing research pathways and understanding the broader landscape of public health research.
14) Chanda (Chamda):
Chanda may refer to an author involved in the study of TB/HIV co-infection. Named contributors enhance the credibility of research findings, showcasing collaborative efforts in the scientific community. Acknowledging researchers fosters an understanding of knowledge dissemination and the importance of collaboration in addressing public health issues.
15) Death:
Death within the context of tuberculosis signifies the severe consequences of untreated TB, especially among co-infected patients. It highlights the urgency of effective treatment strategies and the importance of early detection to prevent mortality rates. Understanding the relationship between TB and death rates is crucial in public health planning.
16) Observation:
Observation refers to the systematic noting of phenomena, pivotal in research. In the study, careful observation of treatment outcomes and patient demographics informs conclusions about TB treatment success factors. Such observations form the foundation for evidence-based clinical practices and inform health policies targeting TB prevention.
17) Discussion:
Discussion in research involves interpreting findings, comparing results to existing literature, and exploring implications. The discussion section in the study analyzes factors influencing TB treatment success, enabling an understanding of how these findings contribute to broader public health strategies and future research directions.
18) Cutting:
Cutting can refer to reducing or alleviating health burdens, notably in public health initiatives aimed at lowering TB mortality rates. The study emphasizes the need for innovative approaches to 'cut' through barriers to successful TB treatment among vulnerable populations, enhancing overall public health outcomes and strategies.
19) Science (Scientific):
Science encompasses the systematic study of the structure and behavior of the physical and natural world. Research on tuberculosis and its interactions with HIV is grounded in scientific principles, underscoring the role of empirical evidence in shaping public health practices and enhancing therapeutic approaches for infectious diseases.
20) Family:
Family plays a critical role in patient support, especially in managing long-term illnesses like tuberculosis. In the study context, family structures impact treatment adherence and overall health outcomes for TB/HIV co-infection patients. Engaging family units in treatment plans may improve compliance and recovery rates.
21) Valley:
Valley may refer to specific regions where TB studies are conducted. Geographic context can influence public health dynamics; understanding regional disease prevalence aids health policymakers in developing focused interventions. Research in varying geographical contexts like valleys informs local approaches to combat TB effectively.
22) Post:
Post may reference post-treatment outcomes or the period after TB treatment completion. Understanding what happens after treatment is essential for evaluating long-term effectiveness and preventing relapse. Addressing post-treatment care is crucial to improving overall survival rates and reinforcing successful public health strategies.
23) Viru:
Viru might refer to the various impacts of viruses on human health, including interactions with diseases like tuberculosis. Exploring viral influences in contexts such as TB can unveil significant insights into co-morbidities. Understanding these interactions is essential for developing comprehensive healthcare strategies for affected populations.
24) Life:
Life is the overarching term that encompasses human health and well-being. In the study context, outcomes regarding tuberculosis directly influence quality of life for patients. Improving TB treatment success translates into enhanced life quality, underscoring the intersection of individual health with broader public health efforts.
Other Health Sciences Concepts:
Discover the significance of concepts within the article: ‘TB Treatment Success in TB/HIV Co-Infection in NE Malaysia’. Further sources in the context of Health Sciences might help you critically compare this page with similair documents:
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