Adiponectin, Leptin, and Physical Activity in Adults: A Review

| Posted in: Science

Journal name: The Malaysian Journal of Medical Sciences
Original article title: Adiponectin, Leptin and Objectively Measured Physical Activity in Adults: A Narrative Review
The Malaysian Journal of Medical Sciences (MJMS) is a peer-reviewed, open-access journal published online at least six times a year. It covers all aspects of medical sciences and prioritizes high-quality research.
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Original source:

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Author:

Ali Nurnazahiah, Pei Lin Lua, Mohd Razif Shahril


The Malaysian Journal of Medical Sciences:

(A peer-reviewed, open-access journal)

Full text available for: Adiponectin, Leptin and Objectively Measured Physical Activity in Adults: A Narrative Review

Year: 2016 | Doi: 10.21315/mjms2016.23.6.2

Copyright (license): CC BY 4.0


Download the PDF file of the original publication


Summary of article contents:

Introduction

This study aimed to compile and analyze existing scientific evidence regarding the effects of objectively measured physical activity on the levels of adiponectin and leptin, two important adipokines associated with metabolic processes. A comprehensive search was conducted across Medline and PubMed databases, focusing on English articles that employed objective measurements of physical activity. The search resulted in 18 eligible articles with a total of 2,026 participants, covering various study designs, including cross-sectional and intervention studies. Notably, 17 studies indicated a positive effect of physical activity on adiponectin levels, while 11 related the effects to leptin levels, though some studies reported weak or inconsistent associations.

Relationship Between Physical Activity and Adipokines

The relationship between physical activity and adipokines was evidenced by several findings. In the cross-sectional studies, a weak to moderate positive association between adiponectin levels and physical activity was reported in two out of five studies, with St-Pierre et al. finding a significant correlation (r = 0.31). Conversely, among studies involving leptin, a weak to moderate inverse association was noted, with St-Pierre's study showing a negative correlation (r = -0.34) between physical activity and leptin levels. Intervention studies also demonstrated potential effects; while some indicated that physical activity could increase adiponectin and decrease leptin levels, overall conclusions were hindered by methodological flaws and inconsistent results across studies.

Conclusion

In conclusion, this review highlights the potential benefits of objectively measured physical activity on adiponectin and leptin levels in adults, with stronger evidence mainly found in cross-sectional studies. Despite some positive findings regarding the influence of physical activity on these adipokines, the need for further rigorous research is evident. Future studies should focus on well-designed randomized controlled trials that include varying intensities and durations of physical activity to clarify the relationship with adipokines. Such investigations are crucial for better understanding the impacts of physical activity on health, particularly in high-risk populations with metabolic issues.

FAQ section (important questions/answers):

What was the objective of the study regarding physical activity?

The study aimed to compile and analyze scientific evidence on the effects of objectively measured physical activity on adiponectin and leptin levels, focusing on their relationships in adults.

How many articles met the inclusion criteria for the study?

A total of 18 articles involving 2,026 respondents met the inclusion criteria, incorporating various study designs such as cross-sectional and intervention studies.

What associations were found between physical activity and adiponectin levels?

Two out of five studies reported a weak to moderate positive association between adiponectin levels and objectively measured physical activity.

What were the findings concerning leptin levels and physical activity?

Three out of four studies found a weak to moderate inverse association between leptin levels and objectively measured physical activity.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Adiponectin, Leptin, and Physical Activity in Adults: A Review”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Activity:
Activity refers to any bodily movement produced by skeletal muscles that require energy expenditure. It is essential for maintaining physical health and has a significant impact on reducing the risk of chronic diseases, improving mood, and enhancing overall well-being. Objectively measured activity helps in assessing its effectiveness and guidelines for public health.

2) Table:
In the context of scientific studies, tables present organized data visually, allowing for quick comparisons and clear understanding of results. They often summarize findings from different studies, facilitating easier interpretation of complex information regarding the interactions between variables, such as physical activity and adipokines like adiponectin and leptin.

3) Training:
Training involves structured physical activity designed to enhance physical fitness, improve health, and increase performance. In research, training methods can vary significantly, influencing outcomes related to metabolic health indicators like adiponectin and leptin. Training interventions are essential for determining the physiological response in different population groups.

4) Cancer:
Cancer refers to a group of diseases characterized by uncontrolled cell growth. Its relevance in the context of physical activity research is significant; several studies highlight how increased physical activity can lower cancer risk by improving hormonal balance and reducing inflammation, thus serving as a preventive strategy against certain types of cancer.

5) Study (Studying):
A study is a systematic investigation aimed at discovering or interpreting facts regarding phenomena. Studies provide empirical evidence and conclusions based on observed data. In health sciences, studies on the effects of physical activity on metabolic markers improve our understanding of their relationships and inform guidelines for public health.

6) Inflammation:
Inflammation is the body's protective response to injury or infection. Chronic inflammation is linked to various diseases, including obesity, diabetes, and cardiovascular conditions. Research frequently examines how physical activity influences inflammation markers, enhancing our understanding of how lifestyle changes can mitigate chronic inflammatory states in different populations.

7) Male:
Male refers to the biological sex characterized by specific genetic and physiological traits. Research often focuses on population differences, such as male versus female responses to physical activity, hormones, and health outcomes like obesity, adipokines, and inflammation. Understanding these differences is crucial for tailored health interventions.

8) Young women (Young woman):
Young women represent a specific demographic group studied to understand the impact of physical activity on health markers such as adiponectin and leptin. Their unique physiological and hormonal profiles often lead to different responses to physical activity compared to other groups, making them vital subjects for research.

9) Disease:
Disease refers to any condition that impairs normal functioning, often characterized by specific symptoms and signs. Physical activity plays a critical role in preventing and managing diseases, including obesity, diabetes, and heart disease. Understanding its effects can help develop public health recommendations and interventions.

10) Blood:
Blood is a vital fluid that circulates through the body, supplying oxygen and nutrients while removing waste. In metabolic studies, blood samples are often analyzed to measure levels of hormones like leptin and adiponectin, providing insight into energy metabolism, inflammation, and the effects of physical activity.

11) Diet:
Diet refers to the kinds of food consumed and their implications for health. In studies of physical activity, diet is a critical variable since nutritional intake can influence metabolic responses and hormone levels. Effective dietary interventions coupled with physical activity can enhance health outcomes.

12) Life:
Life signifies the condition of living organisms. In health studies, quality of life is often a measure of how well individuals manage daily activities and enjoy life. The interaction between lifestyle factors such as diet and physical activity can significantly affect overall life quality.

13) Hara:
Hara is likely a reference to a specific author or research study related to the effects of physical activity on hormonal levels. Acknowledging authors is essential in scientific discussions, as they contribute to the credibility and understanding of specific findings in health-related research.

14) Post:
Post signifies the time after an event. In research, it often applies to measurements taken after an intervention, such as post-training hormonal or metabolic assessments. Understanding changes after interventions aids in determining the effectiveness of physical activity programs and their influence on health markers.

15) Measurement:
Measurement refers to the process of obtaining quantitative data about a variable. In studies, accurate measurement of physical activity levels, metabolic markers, and body composition is crucial for assessing the relationship between lifestyle factors and health outcomes. Reliable measurements support valid conclusions in scientific research.

16) Quality:
Quality pertains to the standard of something, including the effectiveness of health interventions. High-quality studies yield reliable data that contribute to evidence-based recommendations for physical activity and dietary practices. Ensuring quality in study design, execution, and measurement is fundamental in yielding meaningful health insights.

17) Rules:
Rules in scientific research refer to systematic guidelines and standards that ensure reliability and validity in the study. These rules govern methodological approaches to gather data, conduct analyses, and interpret findings. Adhering to established rules helps maintain scientific integrity in physical activity and health research.

18) Food:
Food is crucial for providing energy and nutrients essential for life. In health studies, food intake correlates with physical activity levels, impacting metabolism, energy balance, and disease risk. Understanding the interactions between diet and physical activity is vital for developing effective interventions for health improvement.

19) Developing:
Developing refers to countries or regions with lower income and health resources. Research focused on developing areas is crucial to understanding global health disparities, particularly regarding physical activity and related health outcomes. Tailored interventions based on robust research help address these disparities effectively and equitably.

20) Science (Scientific):
Scientific pertains to the methods and principles related to scientific study and knowledge. It emphasizes the importance of empirical evidence in understanding health phenomena, aiding in developing reliable interventions. Scientific scrutiny allows researchers to challenge, verify, and build upon existing knowledge in fields such as nutrition and exercise physiology.

21) Relative:
Relative indicates a comparison between two or more subjects or variables. In health research, understanding the relative differences among groups, such as those based on sex or age, helps refine interventions and tailor approaches to maximize effectiveness in addressing health issues.

22) Medicine:
Medicine signifies the science and practice of diagnosing, treating, and preventing illness. Physical activity forms a significant part of preventative medicine, helping mitigate health risks associated with lifestyle diseases. Research in this domain continues to establish the importance of exercise in promoting optimal health and well-being.

23) Greece:
Greece may pertain to a location of specific studies in health research. Studies conducted in particular geographical contexts help understand how cultural and environmental factors influence health behaviors like physical activity and diet, leading to a deeper comprehension of health outcomes in various populations.

24) Kareli:
Kareli likely refers to a specific author known for researching the impact of physical activity on health metrics. Recognizing contributing researchers is essential in scientific discourse, as their work helps build the body of knowledge surrounding the significance of lifestyle choices for health improvements.

25) Nature:
Nature symbolizes the natural environment and intrinsic attributes of living organisms. In health studies, understanding the interactions between physical activity and natural environmental factors can provide insights into promoting active lifestyles, especially in urban settings where access to natural spaces may influence exercise behaviors.

26) Vetta:
Vetta may denote an author associated with significant findings in health or physical activity studies. The contributions of researchers like Vetta help advance understanding and provide contextual relevance to the discourse surrounding lifestyle factors and their impacts on health outcomes.

27) Sima (Shima):
Shima might represent the name of an author or a specific study focusing on physical activity's effects on health metrics. Acknowledging researchers enhances the narrative of scientific progress and gives credit to contributions in the examination of exercise and its biological implications.

28) Rope:
Rope is mentioned here possibly as a reference to a physical activity, such as skipping rope, which is a form of exercise. Various forms of exercise, including rope activities, can influence metabolic health and adipokine levels, offering practical applications of research findings.

29) Hand:
Hand could refer to manual activities or exercises that engage certain muscle groups. Such physical activities are important in understanding the role of physical movement in overall health, as they contribute to strength, coordination, and metabolic balance.

30) Ter:
Ther may relate to

Other Science Concepts:

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Discover the significance of concepts within the article: ‘Adiponectin, Leptin, and Physical Activity in Adults: A Review’. Further sources in the context of Science might help you critically compare this page with similair documents:

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Concepts being referred in other categories, contexts and sources.

Sedentary time, English articles, Acute exercise.

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