Dry Eye Parameter Comparison: Diabetics vs Non-Diabetics in Kuantan
Journal name: The Malaysian Journal of Medical Sciences
Original article title: Comparison of Dry Eye Parameters between Diabetics and Non-Diabetics in District of Kuantan, Pahang
The Malaysian Journal of Medical Sciences (MJMS) is a peer-reviewed, open-access journal published online at least six times a year. It covers all aspects of medical sciences and prioritizes high-quality research.
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Mohammed Aljarousha, Noor Ezailina Badarudin, Mohd Zulfaezal Che Azemin
The Malaysian Journal of Medical Sciences:
(A peer-reviewed, open-access journal)
Full text available for: Comparison of Dry Eye Parameters between Diabetics and Non-Diabetics in District of Kuantan, Pahang
Year: 2016
Copyright (license): CC BY 4.0
Download the PDF file of the original publication
Summary of article contents:
Introduction
Diabetes mellitus (DM) has emerged as a significant public health issue globally, with its prevalence surging particularly among developing countries. This medical condition is often linked with a variety of microvascular complications, including diabetic retinopathy, which is a leading cause of blindness. A lesser-known complication faced by diabetic patients is dry eye syndrome, characterized by symptoms such as discomfort and irritation in the eyes. This study investigates and compares the prevalence of dry eye symptoms and signs between diabetic and non-diabetic individuals, while also exploring tear functions in diabetic patients with and without dry eye conditions.
Prevalence of Dry Eye Symptoms in Diabetic and Non-Diabetic Populations
The study highlighted a higher occurrence of dry eye symptoms among diabetic subjects (15.9%) compared to non-diabetics (13.6%; p < 0.001). Additionally, diabetic individuals presenting with dry eye symptoms exhibited a significantly higher percentage compared to those without dry eye symptoms (63% versus 36.9%, p < 0.001). The findings revealed that diabetic subjects had notably shorter tear break-up times (TBUT) than their non-diabetic counterparts, indicating compromised tear functions. The average TBUT for diabetic subjects was found to be markedly lower at 5 seconds, compared to 7 seconds in non-diabetics, highlighting the impact of diabetes on eye health.
Conclusion
The results of the study affirm the correlation between diabetes and elevated dry eye symptoms, suggesting that diabetes exacerbates the risks associated with dry eye syndrome. Diabetics exhibited significantly shorter TBUT, while the differences in corneal staining and tear meniscus height between groups did not show as much significance. Given the increase in dry eye prevalence among diabetic patients, there is a call for further research to better understand the relationship between diabetes and ocular health, as well as to advocate for routine eye examinations for diabetic patients to mitigate potential vision problems associated with dry eye syndrome.
FAQ section (important questions/answers):
What is diabetic retinopathy and its global significance?
Diabetic retinopathy is a complication of diabetes affecting the eyes, contributing to blindness. It is the fifth leading cause of blindness worldwide, highlighting the importance of monitoring and managing diabetes effectively to prevent vision loss.
What was the purpose of the dry eye study?
The study aimed to compare dry eye symptoms and signs between diabetic and non-diabetic subjects, as well as assess tear functions in diabetic patients with and without dry eye symptoms to understand the impact of diabetes on eye health.
What significant results were found regarding tear function in diabetics?
The study found that diabetic subjects had significantly shorter tear break-up times compared to non-diabetics. Additionally, diabetic patients with dry eye symptoms exhibited even shorter tear break-up times, indicating potential impairment in tear function related to diabetes.
What are the recommendations based on the study's findings?
The study suggests further research on tear functions in diabetic patients, especially in Malaysia. It recommends incorporating dry eye assessments in diabetes screening programs to enhance patient care and monitor ocular health related to diabetes.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Dry Eye Parameter Comparison: Diabetics vs Non-Diabetics in Kuantan”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Table:
A table is a systematic arrangement of data, usually in rows and columns, making it easier to read, compare, and analyze information. In research articles, tables summarize key findings, such as demographic data, clinical outcomes, or statistical results, facilitating clearer understanding. They are crucial for interpreting data in studies.
2) Tear:
Tears are a watery fluid secreted by the lacrimal glands that lubricate, nourish, and protect the surface of the eye. In the context of ophthalmology, abnormalities in tear production, quality, or composition can lead to conditions like dry eye syndrome, affecting visual acuity and ocular comfort.
3) Study (Studying):
A study refers to a systematic investigation to determine facts, outcomes, or principles, usually involving observation, experimentation, or analysis. In the medical context, studies help guide clinical practices, advance medical knowledge, and improve patient care by evaluating the effects of interventions or understanding disease mechanisms.
4) Sign:
A sign indicates a manifestation of a disease or condition that can be observed or measured by a healthcare professional, such as redness, swelling, or specific clinical findings like tear break-up time. In medical research, identifying signs helps in diagnosing and monitoring disease progression.
5) Surface:
The term 'surface' refers to the outermost layer, particularly in biology where it pertains to tissues such as the corneal surface of the eye. The ocular surface is critical in tear film stability and overall eye health, and its integrity is essential for clear vision and comfort.
6) Disease:
A disease is a pathological condition of a bodily part, an organ, or system resulting from various causes, such as infection, genetic defect, or environmental stress. In relation to diabetes, diseases like diabetic retinopathy and dry eye syndrome highlight the importance of understanding systemic health effects.
7) Rules:
Rules are prescribed guidelines or principles governing behavior or practices in a specific area, such as medical research ethics or clinical trial protocols. In clinical studies, adherence to rules ensures the validity of the research, protects participants' rights, and maintains the integrity of the findings obtained.
8) Observation:
Observation is the action of closely monitoring or inspecting for signs, symptoms, or reactions. In clinical studies, systematic observation of patient outcomes or responses serves as a foundation for data collection, analysis of treatment efficacy, and understanding the impact of health conditions on individuals with predefined parameters.
9) Knowledge:
Knowledge encompasses both theoretical and practical understanding acquired through experience or education. In the medical field, knowledge about diseases, treatments, and patient management is essential for practitioners to make informed clinical decisions and contribute to improved patient outcomes through evidence-based practices.
10) Male:
The term 'male' designates the sex of individuals characterized by specific reproductive anatomy, chromosomal arrangement, and hormonal profiles, typically associated with the production of sperm. In studies about diseases such as diabetes, gender influences disease prevalence, symptoms, and responses to treatment, highlighting gender-specific health considerations.
11) Developing:
Developing refers to the process of growth or advancement, especially in the context of emerging economies or nations facing health challenges. Understanding how diseases like diabetes affect populations in developing countries is crucial for tailoring healthcare strategies and improving global health outcomes, particularly in resource-limited settings.
12) Toxicology:
Toxicology is the study of the adverse effects of chemical substances on living organisms. Understanding toxicological impacts is vital for evaluating the safety of medications, environmental exposures, and lifestyle choices. This field aids in identifying risk factors associated with diseases and developing strategies for prevention and management.
13) Quality:
Quality pertains to the standard or grade of a service or product, encompassing elements like effectiveness, safety, and reliability. In healthcare, maintaining high quality in medical care, treatment protocols, and patient outcomes is paramount for ensuring that health services deliver optimal benefits to patients.
14) Burning (Burn, Burned, Burnt):
Burning refers to a sensory phenomenon characterized by a feeling of heat or discomfort, often associated with pain or irritation. In ocular health, a burning sensation can indicate inflammation, dryness, or other ocular surface disorders, calling for careful assessment and appropriate management strategies to alleviate symptoms.
15) Visit:
A visit typically refers to an appointment or consultation wherein a patient engages with healthcare professionals for assessment, diagnosis, treatment, or follow-up. Regular visits are crucial for monitoring chronic conditions such as diabetes, ensuring timely interventions, and promoting overall health management outcomes for patients.
16) King:
The term 'King' may refer to entities or individuals, but in this context probably holds significance as an author or reference in the medical literature on diabetes or ocular health. Reference to key figures in research underscores the importance of their contributions to advancing medical knowledge.
17) Burning sensation:
Burning sensation describes a specific sensory experience commonly associated with dryness, irritation, or nerve-related conditions in the eye. This symptom is particularly relevant in ocular studies, highlighting the need to address complaints from diabetic patients regarding discomfort and creating essential links between symptoms and diagnostic criteria.
18) Human body:
The human body is a complex biological system composed of various interconnected systems, organs, and tissues working together to maintain life. In medical studies, understanding the body's responses to diseases like diabetes provides insight into complications affecting ocular health, thereby guiding research and treatment strategies.
19) Measurement:
Measurement refers to the process of obtaining the magnitude of a particular attribute, such as time, distance, or quantity. In healthcare, accurate measurement of clinical parameters such as tear break-up time or corneal staining is vital for diagnosing conditions like dry eye syndrome and assessing treatment effectiveness.
20) Discussion:
Discussion is a critical analysis of research findings, interpretations, and implications within scientific literature. In medical studies, a well-structured discussion contextualizes the results, explores their significance, compares them with existing literature, and offers insights for future research directions and clinical applications.
21) Irritation:
Irritation refers to the discomfort or inflammatory response elicited by various stimuli, including environmental factors or underlying health conditions. In ocular health, irritation can lead to symptoms like redness, burning, or itching, often prompting investigations into possible underlying causes, particularly in patients with chronic conditions such as diabetes.
22) Education:
Education involves systematic learning processes, focusing on acquiring knowledge and skills. In healthcare, education is vital for both practitioners and patients, ensuring an understanding of conditions like diabetes and promoting awareness of associated complications such as dry eye syndrome, ultimately leading to better management and outcomes.
23) Blindness:
Blindness is a significant loss of vision, often resulting from various diseases or conditions affecting the eye, such as diabetic retinopathy. Understanding the causes and prevention strategies for blindness is crucial for public health initiatives, as it impacts an individual's quality of life, independence, and overall well-being.
24) Attending:
Attending describes the act of being present at an event or a gathering, particularly in clinical settings such as medical appointments or healthcare facilities. Attending to patients' needs during consultations is essential for effective diagnosis, treatment planning, and fostering long-term healthcare relationships between providers and patients.
25) Tearing:
Tearing refers to the expulsion of tears from the lacrimal glands, often as a response to physical or emotional stimuli. In ophthalmology, understanding the mechanisms of tearing is essential for diagnosing conditions like dry eye syndrome, guiding effective treatment approaches to enhance eye comfort and health.
26) Itching:
Itching is a sensory symptom characterized by a desire to scratch, often indicating an allergic reaction, irritation, or inflammation. In ocular health, problems such as dry eye syndrome can lead to itchiness, thereby necessitating proper assessment and management to improve patient comfort and visual function.
27) Post:
Post typically refers to something placed or published after an event, such as a report or observation. In contexts like scientific research, 'post' could indicate information shared after data has been collected, contributing to ongoing discussions and advancements in understanding health conditions or treatment outcomes.
28) Pur:
Poor describes a lack of quality, quantity, or effectiveness in a specified context. In healthcare, poor diabetes control may lead to complications such as diabetic retinopathy, affecting eye health and prompting the need for targeted interventions and educational efforts to enhance management outcomes and patient quality of life.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Dry Eye Parameter Comparison: Diabetics vs Non-Diabetics in Kuantan’. Further sources in the context of Science might help you critically compare this page with similair documents:
Diabetes mellitus, Diabetes, Systemic disease, Diabetic Retinopathy, Retrospective study, Dry eye symptoms, Dry eye disease, Control subjects, Clinical tests, Convenience sampling method, Diabetic subjects, Medical file, Non diabetics, Diagnostic Signs, Non-diabetic subjects, Ocular history.