Conjunctival Myxoma-A Case Report
Journal name: The Malaysian Journal of Medical Sciences
Original article title: Conjunctival Myxoma-A Case Report
The Malaysian Journal of Medical Sciences (MJMS) is a peer-reviewed, open-access journal published online at least six times a year. It covers all aspects of medical sciences and prioritizes high-quality research.
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Anuradha Calicut Kini Rao, Bhavna Nayal
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The Malaysian Journal of Medical Sciences:
(A peer-reviewed, open-access journal)
Full text available for: Conjunctival Myxoma-A Case Report
Year: 2013
Copyright (license): CC BY 4.0
Summary of article contents:
Introduction
Ocular myxomas are rare neoplasms that originate from primitive mesenchyme, usually benign in nature. The most well-known is cardiac myxoma, but these tumors can also appear in other tissues, including the ocular region. Among them, conjunctival myxomas are particularly rare, and they can be misdiagnosed as other lesions, such as amelanotic nevi or cysts. This report documents a case of conjunctival myxoma in a 33-year-old male, which was initially diagnosed as a conjunctival cyst but was confirmed through histopathological examination.
Histopathological Features of Conjunctival Myxoma
Histopathological analysis revealed the conjunctival myxoma consisted of spindle and fusiform cells arranged in a loose myxoid stroma, with evidence of cystic changes. Notably, the tumor presented intracytoplasmic and intranuclear inclusions, along with a few giant cells and mast cells. This distinct cellular morphology and tissue structure differentiate conjunctival myxomas from other conjunctival lesions. Additionally, the presence of cystic components and specific cell types in this benign tumor underscores the necessity for accurate diagnosis and management.
Conclusion
In conclusion, conjunctival myxomas are uncommon ocular lesions that require careful assessment to distinguish them from a range of clinical mimics. Complete excision remains the primary treatment approach, as potential recurrences are rare. Furthermore, the existence of conjunctival myxomas may signal underlying conditions or syndromes, necessitating comprehensive clinical evaluation. This case illustrates the importance of recognizing the distinct histological features of conjunctival myxomas for timely diagnosis and appropriate patient management.
FAQ section (important questions/answers):
What are ocular myxomas and where do they typically occur?
Ocular myxomas are rare benign neoplasms, primarily arising in the eye. They can also occur in various other tissues, including the heart, skin, and bones. Conjunctival myxoma is a specific type found on the conjunctiva, often mistaken for other lesions.
What were the symptoms of the conjunctival myxoma case reported?
In the reported case, a 33-year-old male presented with a painless, gradually enlarging swelling in the left eye's conjunctiva. He experienced redness but no pain or discharge, and the ophthalmological examination showed a well-defined cystic mass, initially diagnosed as a conjunctival cyst.
How is conjunctival myxoma diagnosed histopathologically?
Histopathological examination of conjunctival myxoma reveals loose myxoid stroma containing spindle and fusiform cells, often with intracytoplasmic vacuoles, giant cells, and mast cells. These features distinguish it from other conjunctival lesions, including various benign and malignant tumors.
What is the treatment for conjunctival myxomas?
Conjunctival myxomas are treated through complete excision of the lesion. This surgical approach is typically effective, and recurrences after excision are rare. Post-treatment monitoring is advised to check for any potential associated syndromes.
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Differentiated from, Local anesthesia, Adult, Clinical diagnosis, Histopathological examination, Slit lamp examination, Squamous cell carcinoma, Visual Symptoms, Benign lesion, Malignant fibrous histiocytoma, Complete excision, Neoplasm, Alcian blue, Spindle cell lipoma, Neutrophils and Lymphocytes, Soft tissue tumor, Myxoid stroma, Systemic abnormalities, Spindle-shaped cells, Excised, Ocular lesion, Absence of recurrence, Malignant lesion, Visual symptom, Conjunctival lesions, Benign.