Probiotic paste vs. chlorhexidine for chronic periodontitis treatment.

| Posted in: Science

Journal name: Journal of Indian Society of Periodontology
Original article title: Comparative evaluation of locally delivered probiotic paste and chlorhexidine gel as an adjunct to scaling and root planing in treating chronic periodontitis: A split-mouth randomized clinical trial
The Journal of Indian Society of Periodontology (JISP) publishes original scientific articles on periodontology (the study of supporting structures of teeth) and oral implantology. It is a bimonthly open-access journal with special issues for specific occasions.
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Original source:

This page is merely a summary which is automatically generated hence you should visit the source to read the original article which includes the author, publication date, notes and references.

Author:

Jeevanandam Vishnusripriya, Anil Melath, Mohammed Feroz, Kayakool Subair, Nanditha Chandran


Journal of Indian Society of Periodontology:

(A bimonthly open-access journal)

Full text available for: Comparative evaluation of locally delivered probiotic paste and chlorhexidine gel as an adjunct to scaling and root planing in treating chronic periodontitis: A split-mouth randomized clinical trial

Year: 2022 | Doi: 10.4103/jisp.jisp_704

Copyright (license): CC BY-NC-SA


Summary of article contents:

Introduction

Periodontal disease is a chronic microbial infection that arises from a combination of pathogenic bacterial presence, lack of beneficial bacteria, and host susceptibility. Traditional treatment methods primarily involve mechanical debridement alongside the use of antibiotics, which often fall short in eradicating harmful oral microorganisms. Recent advancements in periodontal therapy have introduced the concept of probiotics as local drug delivery systems (LDD), offering potential benefits due to their natural antimicrobial and anti-inflammatory properties. This study aimed to compare the efficacy of a locally delivered probiotic paste versus chlorhexidine gel in conjunction with scaling and root planing (SRP) in patients with chronic periodontitis.

The Advantages of Probiotics in Periodontal Treatment

The research highlighted the promising role of probiotics in improving oral health by modulating the mucosal immune response and outcompeting pathogenic bacteria. The study involved a split-mouth randomized controlled trial with ten participants diagnosed with chronic periodontitis. Various clinical parameters, including gingival index (GI), bleeding index (BI), probing pocket depth (PPD), and clinical attachment level (CAL), were evaluated over nine weeks. Results showed that patients receiving the probiotic LDD exhibited significant improvements in GI, BI, PPD, and CAL compared to those treated solely with SRP or chlorhexidine. This suggests that probiotics may provide an effective adjunct therapy for managing periodontal disease, particularly amid increasing antibiotic resistance.

Conclusion

The findings of this study indicate that probiotic-based LDD formulations present a viable and beneficial alternative to conventional agents like chlorhexidine for the treatment of periodontal disease. The sustained release properties, favorable pH, viscosity, and overall efficacy demonstrate the potential of probiotics to enhance periodontal health while minimizing side effects commonly associated with synthetic drugs. Future research involving larger sample sizes and long-term follow-up studies is warranted to further explore the clinical implications and applications of probiotics in periodontal therapy.

FAQ section (important questions/answers):

What are the main causes of periodontal diseases?

The main causes include dysbiotic bacteria, absence of beneficial bacteria, and host susceptibility, leading to a complex pathogenesis that may necessitate new antimicrobial treatments.

What was the objective of the study involving probiotic paste?

The study aimed to assess the effectiveness of locally delivered probiotic paste compared to chlorhexidine gel as an adjunct to scaling and root planing in patients with chronic periodontitis.

How was the study conducted to evaluate the probiotic paste?

A split-mouth randomized controlled trial was performed with 10 healthy participants, where different treatment combinations (SRP, SRP + chlorhexidine, SRP + probiotic paste) were used on distinct quadrants.

What were the significant findings of the clinical trial?

The results showed that the probiotic paste led to notable improvements in gingival index, bleeding index, probing pocket depth, and clinical attachment level compared to chlorhexidine and control.

What are the implications of using probiotics in periodontal treatment?

Probiotics present a promising alternative to antibiotics, offering natural antimicrobial properties and minimal side effects. They could enhance both oral and systemic health.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Probiotic paste vs. chlorhexidine for chronic periodontitis treatment.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

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2) Drug:
A drug is a substance used for medical treatment, specifically to prevent, diagnose, or alleviate symptoms of diseases. Understanding the properties and effects of drugs is crucial in pharmacology, where drugs are studied for their therapeutic benefits and potential side effects, ensuring safe and effective healthcare practices for patients.

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A study refers to detailed research or analysis undertaken to investigate specific hypotheses or questions. In clinical or pharmaceutical contexts, studies are essential as they provide evidence-based conclusions about the efficacy and safety of treatments, medications, or interventions, contributing valuable knowledge to the field of medicine and healthcare.

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Disease is a pathological condition that alters normal bodily functions, often leading to symptoms like pain and dysfunction. Understanding diseases is vital for developing effective treatments and preventive measures. Research in this area aims to identify causes, risk factors, and interventions, ultimately improving patient outcomes and public health.

5) Bleeding:
Bleeding involves the loss of blood from the vascular system, which can occur internally or externally. In the context of periodontal health, bleeding often indicates inflammation or gum disease. Identifying and managing bleeding is essential in dentistry and medicine, to prevent further complications and ensure proper healing.

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Discover the significance of concepts within the article: ‘Probiotic paste vs. chlorhexidine for chronic periodontitis treatment.’. Further sources in the context of Science might help you critically compare this page with similair documents:

Statistical analysis, Randomized controlled trial, World Health Organization, Periodontal disease, Gingival index, Bleeding index, Glycerol, Antibiotic resistance, Antimicrobial therapy, Chronic periodontitis, Chlorhexidine gel, Scaling and root planing, Probing pocket depth, Clinical attachment level, Local Drug Delivery, Systemic effect, Oral microbiota, Dysbiotic bacteria, Locally delivered probiotic paste, Lactobacillus sporogenes, Formulation of probiotic paste.

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