PRF for enhanced palatal healing post-free gingival graft: Case series
Journal name: Journal of Indian Society of Periodontology
Original article title: Platelet-rich fibrin as an adjunct to palatal wound healing after harvesting a free gingival graft: A case series
The Journal of Indian Society of Periodontology (JISP) publishes original scientific articles on periodontology (the study of supporting structures of teeth) and oral implantology. It is a bimonthly open-access journal with special issues for specific occasions.
This page presents a generated summary with additional references; See source (below) for actual content.
Original source:
This page is merely a summary which is automatically generated hence you should visit the source to read the original article which includes the author, publication date, notes and references.
Mihir Raghavendra Kulkarni, Betsy Sara Thomas, Jothi M. Varghese, Giliyar Subraya Bhat
Journal of Indian Society of Periodontology:
(A bimonthly open-access journal)
Full text available for: Platelet-rich fibrin as an adjunct to palatal wound healing after harvesting a free gingival graft: A case series
Year: 2014 | Doi: 10.4103/0972-124X.134591
Copyright (license): CC BY-NC-SA
Summary of article contents:
Introduction
Free gingival grafts (FGGs) are commonly utilized in periodontal plastic surgery for the augmentation of attached gingiva, yet they can cause significant morbidity at the donor site in the hard palate, including pain, discomfort, and bleeding. This can dissuade clinicians from using them despite their favorable outcomes. Platelet-rich fibrin (PRF), a second-generation platelet concentrate, has been recognized for its wound healing benefits, particularly due to its growth factors and supportive scaffold for tissue regeneration. This case series aims to investigate the impact of PRF on healing and postoperative morbidity at FGG donor sites.
The Role of Platelet-Rich Fibrin in Wound Healing
In this study involving 18 systemically healthy patients, the palatal wounds of 10 patients were dressed with PRF, while 8 received only a periodontal pack. The results indicated notable differences in healing outcomes; those treated with PRF experienced complete wound closure in 14 days, with reduced inflammation and discomfort reported. In contrast, the control group exhibited lagging recovery, with incomplete wound closure and notable inflammation even at the two-week mark. Moreover, patients who received PRF reported significantly less postoperative pain on the Wong and Baker Faces Scale compared to their counterparts, suggesting that PRF not only enhances wound healing but also mitigates patient discomfort.
Conclusion
This case series highlights the efficacy of PRF as a biologically active dressing for enhancing the healing process of palatal donor sites following FGG procedures. By facilitating faster wound closure and reducing postoperative morbidity, PRF addresses significant concerns associated with the use of FGGs. The findings point towards a promising avenue in periodontal surgery that merits further exploration through controlled studies, evaluating the broader implications and applications of this innovative biomaterial in surgical practices.
FAQ section (important questions/answers):
What is the purpose of using platelet-rich fibrin (PRF)?
Platelet-rich fibrin (PRF) enhances wound healing by stimulating angiogenesis and epithelialization. It acts as a bioactive dressing, potentially reducing postoperative morbidity at donor sites of free gingival grafts (FGGs).
How was the effectiveness of PRF assessed in the study?
The effectiveness of PRF was assessed by clinically evaluating postoperative healing at 7, 14, and 21 days, alongside patient-reported morbidity through interviews regarding pain levels using the Wong and Baker Faces Scale.
What were the key findings regarding PRF use in donor site healing?
Sites treated with PRF showed complete wound closure by 14 days, less inflammation, and reduced postoperative discomfort compared to sites where only a periodontal pack was used.
How do PRF-treated patients differ from those without PRF treatment?
Patients treated with PRF reported significantly lower pain scores and experienced a faster healing process, with more complete epithelialization and lesser signs of inflammation at their palatal donor sites.
What future research is suggested regarding PRF in periodontal surgery?
Further well-designed studies are needed to substantiate the benefits of PRF in enhancing palatal healing. Researchers may also explore the impact of PRF on the tissue thickness at donor sites.
Other Science Concepts:
Discover the significance of concepts within the article: ‘PRF for enhanced palatal healing post-free gingival graft: Case series’. Further sources in the context of Science might help you critically compare this page with similair documents:
Clinical evaluation, Angiogenesis, Epithelialization, Hemostasis, Growth factor, Free gingival graft, Biomaterial, Platelet-rich-fibrin, Pain Rating Scale, Post-operative morbidity.