Gingival enlargement in von Willebrand disease: A case report

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Gingival enlargement in von Willebrand disease: A case report”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Bleeding:
Bleeding is a primary concern in von Willebrand disease (vWD), a condition characterized by recurrent episodes that can lead to severe health complications. Patients experience abnormal bleeding due to a deficiency in von Willebrand factor, which impairs platelet adhesion and contributes to prolonged bleeding episodes. Hence, the management of bleeding is crucial in vWD patients.

2) Table:
The term 'Table' refers to the organized presentation of laboratory investigation results in the case report, summarizing crucial data used for diagnosing vWD. It provides insights into the patient's medical condition and helps compare values that inform treatment decisions. These tables play a significant role in understanding the implications of the disease.

3) Disease:
Disease, specifically von Willebrand disease (vWD), is an inherited bleeding disorder that affects individuals regardless of sex. It is caused by a deficiency or dysfunction of von Willebrand factor, leading to various bleeding symptoms. The prevalence and genetic implications of this disease make it significant in both clinical and familial contexts.

4) Marriage:
Marriage, particularly in the context of consanguineous marriages, is relevant to the genetic transmission of von Willebrand disease. The patient’s family history reveals that both parents were related by blood, which may increase the likelihood of passing on genetic disorders like vWD to their offspring, highlighting the importance of awareness in familial history.

5) Sign:
Sign refers to the clinical indicators observed during examinations of vWD patients. Common signs include spontaneous bleeding, gingival enlargement, and abnormal responses during hemostatic assessments. These signs are crucial for diagnosing the disease and determining appropriate treatment protocols, making them vital for successful management.

6) Family:
Family history plays a pivotal role in the genetic understanding of von Willebrand disease, as it is often hereditary. In this case, multiple family members were identified as suffering from vWD, emphasizing the importance of familial patterns in diagnosing and understanding the risk factors associated with this condition.

7) Suffering:
Suffering describes the experiences of patients with von Willebrand disease, who deal with recurrent bleeding and psychological challenges stemming from their condition. The impact on their quality of life can be significant, necessitating comprehensive treatment strategies and psychological support to manage their symptoms effectively.

8) Hygiene (Hygienic):
Hygiene is crucial for patients suffering from vWD, particularly in oral care, as maintaining proper dental hygiene is challenging due to the fear of uncontrolled bleeding. Educating patients about hygiene practices is essential to prevent further complications while managing their bleeding disorder effectively.

9) Blood:
Blood plays a key role in the context of von Willebrand disease, where the disorder directly affects the ability of blood to clot due to defective von Willebrand factor. Understanding blood function and management is fundamental for treating bleeding disorders to ensure patient safety throughout medical and dental procedures.

10) Srinagar:
Srinagar is significant as the geographical location where the reported patient resides. This aspect contextualizes the case study within a specific demographic, which may have unique healthcare access and genetic traits that influence the prevalence and management of conditions like von Willebrand disease.

11) Visit:
Visit pertains to the medical appointments that the patient had to make to seek treatment for her symptoms. Each visit was integral in monitoring her health status, guiding the necessary interventions, and updating her treatment plan, showcasing the importance of continuous medical care in managing chronic diseases.

12) Study (Studying):
Study refers to the research context in which von Willebrand disease was initially described and further investigated in multiple epidemiologic studies. The scientific studies surrounding vWD are essential for improving diagnosis, treatment methods, and understanding the broader implications of the disease within populations.

13) Inflammation:
Inflammation is a common symptom in patients with vWD and can often result from hormonal treatments. It may manifest as swelling and redness in the gums, impacting oral health. Addressing inflammation is critical in the treatment protocol to ensure better outcomes for patients with bleeding disorders.

14) Line:
Line refers to the lineage or familial line in the context of genetic disorders like von Willebrand disease, highlighting the importance of lineage in understanding inherited conditions. Tracking the disease within family lines illustrates the genetic risks and informs treatment and preventive measures.

15) Drug:
Drug refers to the medications administered to manage symptoms of von Willebrand disease. Proper drug usage, including antifibrinolytics and factor VIII concentrates, is vital for preventing hemorrhagic complications during dental and surgical procedures, thus ensuring patient safety and effective treatment.

16) Observation:
Observation is critical in monitoring the patient for any signs of bleeding and complications following dental procedures in vWD management. Continuous observation is necessary to ensure that appropriate interventions can be immediately applied, enhancing patient safety and outcomes.

17) Discussion:
Discussion refers to the analysis and exploration of vWD within the medical community, highlighting its prevalence, treatment strategies, and complications. Effective discussions prompt further research and improvements in clinical practices surrounding this hereditary bleeding disorder.

18) Antibiotic (Antibacterial):
Antibiotic refers to the medications prescribed postoperatively to prevent infections in vWD patients following surgical interventions. The proper use of antibiotics is essential in managing complications due to the increased risk of infections during dental procedures in these individuals.

19) Swelling:
Swelling is a physical symptom most commonly associated with inflammation in vWD patients. Allergic reactions or localized inflammation in the mucosal tissues may lead to significant discomfort and necessitate appropriate management strategies to alleviate the patient's symptoms.

20) Account:
Account refers to the management of patients' medical histories and symptoms as they relate to von Willebrand disease. Providing a comprehensive account of symptoms and family history is essential for diagnosis, treatment planning, and improving overall healthcare delivery.

21) Allergy:
Allergy refers to potential adverse reactions patients might have to certain medications, such as factor VIII. Monitoring for allergies is crucial during treatment, as it can significantly impact medical management and necessitate adjustments to the prescribed therapies.

22) Surface:
Surface refers to the soft tissues in the oral cavity, particularly the gums affected by von Willebrand disease. The condition of the surface tissues plays a significant role in indication bleeding patterns and must be carefully assessed to devise effective treatment strategies.

23) Desire:
Desire indicates the patient's expectations regarding her medical intervention options, specifically related to menorrhagia treatment. A clear understanding of a patient's desires regarding treatment can guide healthcare providers in making informed decisions about their management plans.

24) Edema (Oedema):
Edema refers to the swelling resulting from inflammation often seen in the gingival tissues of vWD patients. Proper evaluation and management of edema are crucial to ensure patient comfort and minimize bleeding risks during dental procedures.

25) Fear:
Fear is a psychological response faced by patients with vWD, particularly concerning bleeding risks during dental treatment. Addressing patient fears is essential for providing effective care and enhancing their overall experience during medical and dental interventions.

26) Pain:
Pain refers to the physical discomfort that patients may experience due to their bleeding episodes or after dental procedures. Effective pain management is a critical component of treatment for patients with von Willebrand disease to improve their quality of life.

27) Post:
Post refers to the period following dental treatment or surgery where patients need careful monitoring for complications. Post-operative care is essential in managing patients with vWD, as they face higher risks for bleeding and infection during this recovery phase.

28) Life:
Life encapsulates the overall impact that von Willebrand disease has on patients' daily living and quality of life, as chronic bleeding can significantly affect their physical and emotional well-being. Understanding the life-long implications of this disorder is crucial for managing it effectively.