Efficacy of β-tri calcium phosphate vs. PRP for intrabony defects.
Journal name: Journal of Indian Society of Periodontology
Original article title: Comparative evaluation of clinical efficacy of β-tri calcium phosphate (Septodont–RTR)™ alone and in combination with platelet rich plasma for treatment of intrabony defects in chronic periodontitis
The Journal of Indian Society of Periodontology (JISP) publishes original scientific articles on periodontology (the study of supporting structures of teeth) and oral implantology. It is a bimonthly open-access journal with special issues for specific occasions.
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Jyostna Pinipe, Narendra Babu Mandalapu, Sesha Reddy Manchala, Satheesh Mannem, N.V.S. Sruthima Gottumukkala, Suneetha Koneru
Journal of Indian Society of Periodontology:
(A bimonthly open-access journal)
Full text available for: Comparative evaluation of clinical efficacy of β-tri calcium phosphate (Septodont–RTR)™ alone and in combination with platelet rich plasma for treatment of intrabony defects in chronic periodontitis
Year: 2014 | Doi: 10.4103/0972-124X.134573
Copyright (license): CC BY-NC-SA
Summary of article contents:
Introduction
Periodontitis is a progressive inflammatory disease that leads to the destruction of the supporting structures of the teeth, including the periodontal ligament and alveolar bone. The aim of regenerative periodontal therapy is to restore the attachment apparatus to its pre-disease condition. Various methods, including the use of bone grafts and regenerative biologic agents, have been employed to enhance periodontal healing. This study investigates the effectiveness of β-tri calcium phosphate (β-TCP) combined with platelet-rich plasma (PRP) compared to β-TCP alone in treating intrabony defects, analyzing clinical outcomes over a six-month period.
Summary of One Important Concept: Comparative Effectiveness of PRP and β-TCP
The research involved ten patients with chronic generalized periodontitis using a split-mouth design to compare the clinical outcomes of two treatment modalities: β-TCP with PRP and β-TCP alone. Both groups showed substantial improvements, with significant reductions in probing pocket depth (PPD) and gains in clinical attachment level (CAL) after six months. However, the intergroup comparison revealed no statistically significant differences between the two treatment modalities in terms of PPD reduction and CAL gain. This suggests that the addition of PRP to β-TCP therapy does not confer additional benefits in the management of periodontal defects within the studied timeframe, indicating that β-TCP alone may be sufficient for achieving clinical improvements.
Conclusion
In conclusion, while both treatments resulted in significant clinical improvements, the study demonstrated that the combination of PRP and β-TCP does not provide considerable additional benefits over β-TCP alone in treating intrabony periodontal defects within a six-month follow-up period. The results highlight the effectiveness of β-TCP as a standalone treatment; however, further studies with larger sample sizes and longer follow-ups are needed to comprehensively assess the potential advantages of integrating PRP with β-TCP in periodontal regeneration. Overall, the findings contribute to the understanding of optimal treatment strategies for periodontal defects.
FAQ section (important questions/answers):
What was the aim of the study on β-TCP and PRP?
The study aimed to evaluate the clinical outcomes of combining β-tri calcium phosphate (β-TCP) with platelet-rich plasma (PRP) versus using β-TCP alone in treating intrabony defects over a six-month period.
How many patients were involved in the study?
A total of ten patients with chronic generalized periodontitis participated in the study, with each having contralateral intrabony defects treated using a split-mouth design.
What clinical parameters were measured after the treatment?
The clinical parameters measured included Plaque Index (PI), Gingival Index (GI), Probing Pocket Depth (PPD), and Clinical Attachment Level (CAL) after six months following the surgical procedures.
What were the main findings regarding the combination treatment?
The study found that while both treatments led to significant improvements in clinical parameters, the addition of PRP did not show statistically significant additional benefits compared to β-TCP alone.
What are the implications of this study’s results?
The results suggest that using PRP alongside β-TCP does not provide added clinical advantages for treating intrabony defects within a six-month follow-up, indicating that β-TCP alone is effective.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Efficacy of β-tri calcium phosphate vs. PRP for intrabony defects.’. Further sources in the context of Science might help you critically compare this page with similair documents:
Plaque index, Gingival index, Platelet-rich plasma, Surgical Procedure, Therapeutic modalities, Probing pocket depth, Postoperative care, Clinical attachment level, Clinical outcome, Long-term studies, Intrabony defect.