Efficacy of a synthetic graft for treating intrabony defects
Journal name: Journal of Indian Society of Periodontology
Original article title: Evaluation of the efficacy of a bioactive synthetic graft material in the treatment of intrabony periodontal defects
The Journal of Indian Society of Periodontology (JISP) publishes original scientific articles on periodontology (the study of supporting structures of teeth) and oral implantology. It is a bimonthly open-access journal with special issues for specific occasions.
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Vishakha Grover, Anoop Kapoor, Ranjan Malhotra, Ranjit Singh Uppal
Journal of Indian Society of Periodontology:
(A bimonthly open-access journal)
Full text available for: Evaluation of the efficacy of a bioactive synthetic graft material in the treatment of intrabony periodontal defects
Year: 2013 | Doi: 10.4103/0972-124X.107484
Copyright (license): CC BY-NC-SA
Summary of article contents:
Introduction
This study investigates the effectiveness of bioactive ceramic fillers, specifically bioactive glass, in treating intrabony periodontal defects in patients with moderate to severe chronic periodontitis. Periodontal therapy aims to restore lost periodontal structures due to disease or trauma, emphasizing the necessity for successful regeneration of the periodontium, including new bone and periodontal ligament formation. Traditional methods such as guided tissue regeneration and osseous grafting have shown promise, but recent advancements have expanded the exploration of various alloplastic materials, including bioactive ceramics like bioactive glass, known for their osteoconductive properties.
Efficacy of Bioactive Glass in Periodontal Regeneration
The study demonstrated a significant mean radiographic defect fill of 64.76% after 6 months of treatment with Novabone Dental Putty, a commercially available bioactive glass. Clinical evaluations also revealed a substantial relative attachment level gain of 2.71 mm and probing pocket depth reduction of 4.21 mm, indicating the material's efficacy in promoting periodontal healing. The results suggest that bioactive glass enhances the regenerative process in intrabony defects, with the majority of defects achieving over 50% fill within the 6-month follow-up period.
Conclusion
The findings from this study highlight the potential of bioactive glass as a favorable treatment option for regenerating periodontal tissues in intrabony defects. With statistically significant improvements in both clinical and radiographic parameters, bioactive glass presents a promising alternative in periodontal therapy, enabling enhanced bone formation and periodontal regeneration. The study underscores the importance of further research to optimize regenerative strategies in clinical settings.
FAQ section (important questions/answers):
What was the purpose of the study on bioactive ceramic fillers?
The study aimed to evaluate the efficacy of bioactive synthetic graft materials in treating intrabony periodontal defects in patients with chronic periodontitis.
What improvements were observed after using bioactive glass for grafting?
After 6 months, significant improvements included a 64.76% radiographic defect fill, a 2.71 mm attachment level gain, and a 4.21 mm reduction in probing pocket depth.
Who were the subjects included in the bioactive glass study?
The study included twelve systemically healthy subjects aged 30-65, all suffering from moderate to severe chronic periodontitis with specific periodontal defects.
What type of bioactive material was used in the study?
The study utilized Novabone Dental Putty, a commercially available bioactive glass composed of calcium-phospho-silicate particulate, which requires no mixing prior to application.
What clinical outcomes were measured during the study?
Clinical outcomes measured included probing pocket depth, relative attachment level, mobility, and gingival index, evaluated before surgery and at 3 and 6 months after grafting.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Efficacy of a synthetic graft for treating intrabony defects”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Study (Studying):
In the context of this research, 'Study' refers to the systematic investigation conducted to assess the efficacy of bioactive glass in treating intrabony periodontal defects. It emphasizes the scientific approach taken to collect, analyze, and interpret clinical data in order to derive meaningful conclusions regarding periodontal therapy.
2) Glass:
'Glass' pertains to bioactive glass, specifically the synthetic graft material utilized in the study. Its significance lies in its osteoconductive properties, which promote bone regeneration and healing in periodontal defects. Understanding its composition and biological interactions is crucial for its application in dental regenerative medicine.
3) Table:
'Table' signifies the structured representation of data collected during the study. In research, it organizes statistical results, making it easier to interpret findings and compare outcomes over different periods. Tables enhance clarity and understanding of clinical improvements in terms of radiographic defect fill and other parameters.
4) Measurement:
'Measurement' involves assessing clinical parameters like probing pocket depth and relative attachment level. Accurate measurement is vital for determining the effectiveness of the graft material. It enables researchers to quantify changes and evaluate outcomes post-treatment, providing insights into the regenerative potential of the bioactive glass.
5) Relative:
'Relative' in this context refers to relative measurements of attachment levels and probing depths compared to baseline data. It underscores the changes in clinical parameters that are directly attributable to the intervention, helping to assess the overall success and efficacy of the treatment over time.
6) Dressing:
'Dressing' refers to the periodontal dressing applied post-surgery to protect the surgical site. Its relevance is in preventing contamination and supporting healing of the gum tissue. Proper care in dressing application can influence patient outcomes and the success of the grafting procedure.
7) Incision:
'Incision' describes the surgical cut made during the periodontal procedure to gain access to the defect. Its relevance lies in the need for precise surgical technique, as proper incisions facilitate effective flap elevation and graft placement, ultimately impacting healing and regeneration.
8) Grafting:
'Grafting' pertains to the surgical procedure of placing bioactive glass into the periodontal defect. It is a critical aspect of the study, as it directly influences bone regeneration. Understanding grafting techniques is essential for improving outcomes in periodontal treatment.
9) Hygiene (Hygienic):
'Hygiene' emphasizes the importance of oral hygiene maintenance as part of the study protocol. Good oral hygiene practices are essential for preventing postoperative complications and ensuring successful graft integration and healing in periodontal therapy.
10) Post:
'Post' relates to the postoperative phase, highlighting the importance of follow-up assessments in evaluating clinical outcomes after treatment. Monitoring patients post-surgery is crucial for understanding the longevity and effectiveness of the bioactive graft material in clinical settings.
11) Reliability:
'Reliability' refers to the consistency and dependability of the measurements taken during the study. Establishing reliable data is critical in research to ensure that the results are valid and can be replicated, thereby enhancing the credibility of findings in periodontal therapy.
12) Observation:
'Observation' is the act of carefully monitoring and recording clinical outcomes over specific time intervals. This is essential in the context of the study as it provides the basis for measuring the effectiveness of bioactive glass in treating periodontal defects.
13) Suffering:
'Suffering' highlights the impact of periodontal disease on individuals, emphasizing the significance of effective treatments. Understanding patients' suffering due to chronic periodontitis underscores the need for innovative approaches, like using bioactive glass for regeneration, in improving their quality of life.
14) Composite:
'Composite' in this context refers to the mixture of bioactive materials used in Novabone Dental Putty. It combines various elements that mimic natural bone, making it significant for clinical applications aiming for successful regeneration and integration within the periodontal environment.
15) Pregnant:
'Pregnant' implies consideration of patient medical status in the study. Pregnant individuals were excluded to avoid potential complications in healing and treatment outcomes. It emphasizes the need to ensure safety and efficacy in the treatment approaches used in periodontal therapy.
16) Disease:
'Disease' refers to chronic periodontitis, the condition being treated in this study. Understanding the pathological mechanisms of periodontal disease is essential to develop effective regenerative therapies, highlighting the importance of research in improving patient outcomes.
17) Filling (Filled):
'Filled' refers to the successful placement of bioactive glass into the intrabony defects, indicating the treatment's procedural success. It signifies the core objective of the study, which is to evaluate the effectiveness of the filling material in promoting bone regeneration.
18) Science (Scientific):
'Science' pertains to the systematic study of the biological and clinical effects of bioactive materials in periodontal treatments. The application of scientific principles in research ensures that conclusions drawn contribute to the advancement of dental medicine and improve patient care.
19) Surface:
'Surface' indicates the interface where bioactive glass interacts with bone tissue. Understanding surface properties is vital for enhancing bonding and facilitating bone regeneration, making it a key aspect of studying bioactive materials in periodontal surgeries.
20) Punjab:
'Punjab' identifies the geographical location where the study was conducted. This is relevant as it contextualizes the research setting and demographic, and it reflects regional healthcare practices and the need for effective dental treatments in local populations.
21) India:
'India' denotes the country where the research was undertaken, providing context for the healthcare landscape. Understanding local practices and patient demographics is critical in evaluating treatment effectiveness and ensuring the findings are relevant to broader clinical settings.
22) Visit:
'Visit' indicates the follow-up appointments scheduled after surgery. These visits are crucial for monitoring patient recovery, assessing clinical outcomes, and ensuring ongoing patient education about oral hygiene practices to enhance the success of the graft material.
23) Silk:
'Silk' refers to the type of sutures used in the surgical procedure. The choice of silk sutures is relevant for optimal healing, providing adequate support for the surgical site and minimizing complications, which is significant in the success of periodontal grafting.
24) Male:
'Male' describes the gender distribution of participants in the study, which included both male and female subjects. Gender specifics can be relevant in many medical studies for analyzing outcomes and understanding demographics related to periodontal disease.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Efficacy of a synthetic graft for treating intrabony defects’. Further sources in the context of Science might help you critically compare this page with similair documents:
Gingival index, Hydroxyapatite, Surgical Procedure, Chronic periodontitis, Periodontal therapy, Periodontal regeneration, Oral hygiene instruction, Clinical parameter, Statistical package for social science, Bioactive Glass.