Assessment of lipid levels in periodontitis patients
Journal name: Journal of Indian Society of Periodontology
Original article title: Assessment of serum levels of triglycerides, total cholesterol, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol in periodontitis patients
The Journal of Indian Society of Periodontology (JISP) publishes original scientific articles on periodontology (the study of supporting structures of teeth) and oral implantology. It is a bimonthly open-access journal with special issues for specific occasions.
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Original source:
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Swati Penumarthy, Gautami S. Penmetsa, Satheesh Mannem
Journal of Indian Society of Periodontology:
(A bimonthly open-access journal)
Full text available for: Assessment of serum levels of triglycerides, total cholesterol, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol in periodontitis patients
Year: 2013 | Doi: 10.4103/0972-124X.107471
Copyright (license): CC BY-NC-SA
Summary of article contents:
Introduction
Periodontal disease is a significant inflammatory condition that leads to destructive changes in the body's cytokine levels, resulting in a catabolic state that affects lipid metabolism, often characterized by hypertriglyceridemia. The primary aim of the study was to assess how periodontal infections impact serum lipid profiles, specifically looking at triglycerides (TGL), total cholesterol (TC), high-density lipoprotein (HDL) cholesterol, and low-density lipoprotein (LDL) cholesterol levels.
Impact of Periodontal Disease on Lipid Levels
In the study, a total of 90 participants were examined, divided into three groups: individuals with healthy gums, those with chronic gingivitis, and those suffering from chronic periodontitis, all aged between 25 to 65 years. Various periodontal health indicators were measured, including Plaque Index, Gingival Index, Probing Depth, and Clinical Attachment Level. Following a 12-hour fasting period, venous blood samples were collected to evaluate serum levels of TGL, TC, HDL, and LDL cholesterol. The findings revealed that individuals with chronic periodontitis exhibited significantly higher levels of TGL, TC, and LDL cholesterol compared to the other groups.
Conclusion
The results of this study underscore the correlation between periodontal disease and altered lipid metabolism, illustrating how inflammatory periodontal conditions can elevate serum lipid levels, particularly in cases of chronic periodontitis. This highlights the importance of monitoring and managing periodontal health, not just for oral outcomes but also for its potential implications on systemic lipid profiles and overall metabolic health.
FAQ section (important questions/answers):
What is the main focus of the study on periodontal disease?
The study aims to evaluate how periodontal infection affects serum levels of triglycerides, total cholesterol, high-density lipoprotein, and low-density lipoprotein in different periodontal health statuses.
How many participants were involved in the periodontal study?
The study included 90 participants categorized into three groups: 30 healthy individuals, 30 with chronic gingivitis, and 30 with chronic periodontitis, aged between 25 to 65 years.
What methods were used to assess periodontal health in the study?
Periodontal health was assessed using the Plaque Index, Gingival Index, Probing Depth, and Clinical Attachment Level, which are standard measures to determine the severity of periodontal disease.
What were the findings regarding triglycerides and cholesterol levels?
The study found significantly higher levels of triglycerides, total cholesterol, and LDL cholesterol in the periodontitis group compared to healthy individuals, indicating a link between periodontal disease and lipid metabolism.
How were blood samples collected for the study?
Venous blood samples were collected after a 12-hour fasting period from the antecubital vein to measure serum levels of triglycerides, total cholesterol, and lipoproteins.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Assessment of lipid levels in periodontitis patients”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Disease:
In this context, 'disease' refers to periodontal disease, which is an inflammatory condition affecting the gums and bone supporting the teeth. It leads to symptoms such as gum bleeding and tooth loss. This study emphasizes the systemic impact of this disease, particularly its influence on lipid metabolism and serum lipid levels.
2) Study (Studying):
'Study' refers to the structured investigation undertaken to assess the relationship between periodontal infection and serum lipid levels. By comparing healthy individuals with those suffering from chronic gingivitis and periodontitis, the study aims to identify significant differences in plasma concentrations of triglycerides and cholesterol, highlighting the broader health implications of periodontal disease.
3) Blood:
'Blood' is crucially relevant in this study as it is the medium through which various biomarkers, including triglycerides and cholesterol, are measured. Blood samples provide insight into systemic changes associated with periodontal disease. Elevated levels of specific lipids in the blood can indicate the body's response to inflammatory conditions caused by periodontal infections.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Assessment of lipid levels in periodontitis patients’. Further sources in the context of Science might help you critically compare this page with similair documents:
Total cholesterol, Low-density lipoprotein cholesterol, High-density lipoprotein cholesterol, Periodontal disease, Plaque index, Gingival index, Triglycerides level, Probing depth, Clinical attachment level, Venous blood sample.