Biofilm and dental implant: The microbial link

| Posted in: Science

Journal name: Journal of Indian Society of Periodontology
Original article title: Biofilm and dental implant: The microbial link
The Journal of Indian Society of Periodontology (JISP) publishes original scientific articles on periodontology (the study of supporting structures of teeth) and oral implantology. It is a bimonthly open-access journal with special issues for specific occasions.
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Original source:

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Author:

Sangeeta Dhir


Journal of Indian Society of Periodontology:

(A bimonthly open-access journal)

Full text available for: Biofilm and dental implant: The microbial link

Year: 2013 | Doi: 10.4103/0972-124X.107466

Copyright (license): CC BY-NC-SA


Summary of article contents:

Introduction

The oral cavity provides an ideal environment for microorganisms due to its nonshedding surfaces, contributing to the complexity of dental plaque, a diverse microbial community that forms on tooth surfaces. Disruptions in the balance between host defenses and microbial pathogenicity can lead to specific infections such as periodontal disease and peri-implant disease. This review focuses on biofilms, particularly in the context of dental implants, examining the factors influencing their formation and the treatment strategies to manage these microbial colonies.

Biofilm Formation and Characteristics

Biofilms are microbial communities characterized by their attachment to surfaces and their ability to resist antimicrobial agents and host immune responses. The process of biofilm formation begins with the acquisition of a pellicle on tooth or implant surfaces shortly after exposure in the oral environment. Initial colonizers, primarily gram-positive cocci and Actinomyces species, attach to the pellicle, followed by secondary colonizers, including pathogens associated with peri-implantitis and periodontitis. Factors such as surface roughness and surface free energy (SFE) considerably influence the extent of biofilm formation, with rougher surfaces promoting greater microbial adherence. This complex interplay of microbial interactions and environmental cues—mediated by quorum sensing—facilitates the establishment of a mature biofilm, which can ultimately contribute to dental ailments like peri-implantitis.

Conclusion

Understanding the dynamics of biofilm formation around dental implants is vital for effectively addressing peri-implant diseases. The intricate relationship between microbial population, surface characteristics, and host response signifies the need for targeted treatments that consider these factors. Future research should focus on developing strategies to disrupt biofilm formation or enhance the host's defenses to mitigate the risks associated with dental implants, potentially improving patient outcomes in oral healthcare.

FAQ section (important questions/answers):

What is a dental biofilm and how does it form?

A dental biofilm is a microbial community that develops on tooth surfaces. It forms when saliva proteins create an acquired pellicle, allowing bacteria to adhere and coaggregate, leading to complex colonies. This process starts within hours of dental cleanliness.

What role do biofilms play in periodontal diseases?

Biofilms are crucial in periodontal diseases as they harbor pathogens responsible for infections like gingivitis, periodontitis, and peri-implantitis. The microbial balance is disrupted, leading to disease progress and potential failure of dental implants.

How do surface properties of dental implants affect biofilm formation?

The roughness and wettability of dental implants significantly influence biofilm formation. Rougher surfaces enhance bacterial attachment, leading to increased plaque buildup, which contributes to inflammatory conditions like peri-implantitis.

What are the initial steps in biofilm formation on dental implants?

Biofilm formation begins with saliva-derived pellicle coating the implants within 30 minutes. Initial colonizers, mainly gram-positive cocci, adhere to this pellicle, setting the stage for later bacterial colonization and biofilm development.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Biofilm and dental implant: The microbial link”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Surface:
The term 'Surface' refers to the outermost layer of a structure, in this context specifically the implant or tooth surface where microorganisms adhere. The surface characteristics, including roughness and wettability, significantly influence biofilm formation and microbial colonization, affecting the health of dental implants and the onset of peri-implant diseases.

2) Species:
In microbiology, 'Species' denotes a distinct group of microorganisms. In the context of this review, it highlights the various bacterial species involved in dental biofilm formation. Species such as Streptococci, Actinomyces, and Fusobacterium play roles in the complexity of plaque microbiology, affecting both oral health and disease processes related to implants.

3) Study (Studying):
'Study' refers to systematic investigations aimed at understanding specific phenomena. Within this review, studies are cited that examine the behavior of biofilms on dental implants, looking at microbial colonization patterns and their effects on periodontal diseases like peri-implantitis, thereby contributing to the scientific understanding of oral microbiology.

4) Disease:
'Disease' typically refers to abnormalities in the body that disrupt normal bodily functions. In this review, it specifically pertains to periodontal diseases and peri-implantitis caused by biofilm-associated infections. The balance between host immune response and microbial pathogenicity is often disrupted, leading to these dental diseases, highlighting the importance of biofilm management.

5) Table:
'Table' in this context signifies a structured arrangement of data presented for clarity. It includes summaries of findings from various related studies on biofilm formation, species interactions, and surface properties affecting bacterial colonization on implants. Tables facilitate easier comparisons of data, enhancing the reader's understanding of the study's implications.

6) Food:
'Food' refers to any substance that provides nutrients to organisms. In the context of this review, it highlights the microbial nutrients sourced from diets, such as sugars. The presence of food in the oral cavity serves as a substrate for bacterial growth, playing a critical role in the process of dental plaque development and subsequent diseases.

7) Human body:
'Human body' is the biological entity composed of various systems and structures, including oral cavity environments conducive to microbial growth. The human body is home to diverse microbial species, with the oral cavity presenting ideal conditions for biofilm formation. Understanding these interactions is crucial to preventing dental diseases and implants' failure.

8) Accumulation (Accumulating, Accumulate):
'Accumulation' refers to the gradual gathering or buildup of substances, such as bacteria in biofilms. In dental health contexts, the accumulation of microbial plaque on tooth surfaces or implants can lead to infections and diseases like peri-implantitis. Understanding accumulation dynamics is vital for developing effective dental care strategies.

9) Fixation:
'Fixation' pertains to the stable attachment of microorganisms to surface materials. In dental contexts, fixation is crucial for biofilm formation on teeth and implants. The initial weak reversible binding develops into irreversible attachment that establishes the biofilm, which is challenging to manage and can lead to periodontal diseases if not addressed.

10) Channel:
'Channel' in biological contexts often refers to pathways for communication or interaction. In the discussion of biofilms, it refers to the signaling mechanisms between bacterial species. This communication facilitates coordination among microbial communities, influencing their behavior, virulence, and overall stability, which can be pivotal in understanding biofilm dynamics in dental health.

11) Reason:
'Reason' signifies the underlying justification for specific phenomena or behaviors. In this context, it relates to the factors influencing biofilm formation and microbial interactions. Understanding the reasons behind these dynamics helps researchers develop better strategies to manage and mitigate dental diseases associated with biofilm-related infections.

12) Animal:
'Animal' refers to non-human organisms, often studied in research for insights related to human health. In this review, animal studies help elucidate the complexities of microbial interactions and biofilm dynamics in dental implants. Such studies provide a foundation for translating findings into clinical implications for human dental health.

13) Water:
'Water' serves as a fundamental solvent facilitating biological processes. In the oral cavity, saliva, which is primarily composed of water, aids in nutrient transport and plays a vital role in the formation of biofilms on teeth and implants. Understanding its role is crucial for grasping how biofilms develop and affect oral health.

14) Sugar:
'Sugar' encompasses carbohydrates that serve as energy sources for bacteria. It is particularly relevant in the oral environment, where sugars from food debris can enhance microbial growth and contribute to dental plaque formation. The metabolism of sugar by bacteria is a contributing factor to numerous dental diseases, emphasizing the need for dietary management.

15) Miti:
'Miti' likely refers to Streptococcus mitis, a specific bacterial species involved in oral biofilms. As an early colonizer, Streptococcus mitis plays a role in initial biofilm formation on tooth and implant surfaces, influencing the development of subgingival pathogenic communities and the overall health dynamics of the oral microbiome.

16) Rich (Rch):
'Rich' in this context often describes environments that are abundant in nutrients. The oral cavity is rich in substrates from saliva and dietary sources, promoting diverse microbial growth. Such nutrient-rich conditions are essential for the establishment and maintenance of biofilms, ultimately impacting dental health and disease progression.

17) Wall:
'Wall' typically refers to cellular structures that provide integrity and protection. In biofilms, the bacterial cell walls participate in intercellular adhesion and biofilm matrix formation. Understanding these structures helps elucidate the physical barriers they create, which protect against host immune responses and antimicrobial treatment, complicating infection management.

18) Hand:
'Hand' might refer to the manual process of conducting research or treatment interventions. In dental contexts, hands-on procedures such as cleanings and surgical interventions are crucial for managing biofilm-related diseases. Additionally, the importance of trained professionals in preventing dental implant failures reflects on the need for skilled hands-on care.

19) Drug:
'Drug' signifies pharmacological agents used to treat infections and diseases. In managing biofilm-related infections around dental implants, local drug delivery systems can target specific bacterial populations effectively. Understanding the interaction between drug delivery and biofilm dynamics is essential for developing successful treatments and improving implant outcomes.

Other Science Concepts:

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Discover the significance of concepts within the article: ‘Biofilm and dental implant: The microbial link’. Further sources in the context of Science might help you critically compare this page with similair documents:

Pathogenesis, Periodontal disease, Gingivitis, Dental plaque, Periodontitis, Gram positive bacteria, Biofilms, Microbial load, In vivo studies, Extracellular Polysaccharide, Bacterial adhesion, Quorum sensing, Bacterial colonization, Peri-implantitis, Dental implant, Surface Roughness, Virulence, Host response.

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