Protective effects of Gardenia ternifolia extracts on liver disease.

| Posted in: Science

Journal name: Journal of Ayurveda and Integrative Medicine
Original article title: Protective effects of leaf aqueous extracts from Gardenia ternifolia Schumach. on alcoholic liver disease in Wistar rats
The Journal of Ayurveda and Integrative Medicine (JAIM) is an open-access publication promoting collaboration between Ayurveda, traditional medicine, and biomedicine, publishing research on integrative health sciences
This page does not contain the article itself; See source (below) for actual content.

Original source:

This page only sums up technical details and meta-data hence you should visit the source to read the original article which includes the author, publication date, notes and references.

Author:

Desmond Nguetsa Sakou, Borris Rosnay Galani Tietcheu


Journal of Ayurveda and Integrative Medicine:

(A monthly peer-reviewed publication)

Full text available for: Protective effects of leaf aqueous extracts from Gardenia ternifolia Schumach. on alcoholic liver disease in Wistar rats

Year: 2024 | Doi: 10.1016/j.jaim.2023.100851

Copyright (license): CC BY-NC-ND 4.0


Download the PDF file of the original publication


Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Protective effects of Gardenia ternifolia extracts on liver disease.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Table:
In scientific literature, 'Table' refers to a systematic arrangement of data or information in rows and columns, making it easier for readers to visualize and comprehend complex results. Tables are crucial in summarizing findings, comparative data, metrics, and statistical analysis, providing clarity and enabling efficient data retrieval in reports.

2) Disease:
'Disease' signifies any abnormal condition affecting the body or mind, characterized by specific symptoms or behavioral signs. In the context of the research, it underscores its implications on health, emphasizing the necessity for understanding pathogenic mechanisms, potential treatments, and preventive measures aimed at combatting such health challenges.

3) Activity:
'Activity' generally pertains to the functioning or operation of a biological compound, organism, or system. It is vital in pharmacology, as it describes how substances, like extracts from Gardenia ternifolia, exhibit various effects on living organisms, particularly in relation to therapeutic properties or pharmacological efficacy.

4) Flavonoid:
'Flavonoid' refers to a class of polyphenolic compounds found in various plants that are known for their antioxidant properties. In the context of this study, flavonoids are relevant as they could influence health outcomes, specifically their ability to combat oxidative stress and inflammation, enhancing liver protection mechanisms.

5) Food:
'Food' encompasses substances consumed to provide nutritional support for the body. In this study, reference to food illustrates the importance of diet in health, specifically addressing the role of edible plants and natural extracts in managing conditions like alcoholic liver disease, demonstrating nutritional strategies for health promotion.

6) Phytochemical:
'Phytochemical' indicates bioactive chemical compounds produced by plants, which contribute to their color, flavor, and disease resistance. Their relevance in the research is substantial as they may hold therapeutic potential, such as antioxidant, anti-inflammatory, or hepatoprotective properties that are crucial in treating various health conditions.

7) Study (Studying):
'Study' refers to the systematic inquiry or research conducted to explore, analyze, or evaluate certain phenomena. In scientific research, studies validate hypotheses or investigate effects and outcomes, contributing profound knowledge to fields from medicine to pharmacology; thus underscoring the importance of rigorous scientific methodologies.

8) Death:
'Death' indicates the cessation of life, which can arise from numerous causes, including diseases like alcoholic liver disease. In medical studies, understanding mortality rates associated with particular conditions emphasizes the urgency of research for effective treatments and public health initiatives targeting prevention and treatment.

9) Animal:
'Animal' refers to living organisms that are within the animal kingdom, typically studied in biological and medical research. The use of animals, like male Wistar rats in this study, is essential for understanding physiological responses, disease mechanisms, and evaluating the effectiveness of treatments before human trials.

10) Relative:
'Relative' signifies a comparison or relationship between quantities, particularly showing how one quantity changes compared to another. In the study, the term applies to values such as relative liver weight, indicating the liver's mass in proportion to the overall body weight, which is crucial for interpreting metabolic effects.

11) Inflammation:
'Inflammation' represents the body’s response to injury, infection, or irritation, characterized by redness, swelling, and pain. It plays a critical role in various diseases, including liver diseases, where chronic inflammation can result in tissue damage; thus, understanding it is vital for developing therapeutic interventions.

12) Cancer:
'Cancer' denotes a group of diseases characterized by uncontrolled cell growth that can spread to other parts of the body. In discussing liver diseases, particularly alcoholic liver disease, understanding potential pathways leading to cancer can inform preventive strategies and influence treatment protocols for affected individuals.

13) Powder:
'Powder' refers to a finely ground substance that retains the properties of the original material. In this context, it often signifies the processed form of plant materials, like the leaves of Gardenia ternifolia, which are utilized in research to evaluate their biological effects and potential therapeutic uses.

14) Water:
'Water' is a vital solvent and medium essential for countless biological processes. In the context of this study, its role is crucial as the extraction solvent for pharmacologically active compounds from plants, highlighting the importance of solvent choice in the evaluation of phytochemical properties and potencies.

15) Male:
'Male' refers to the biological sex that typically produces small, mobile gametes (sperm). This distinction is important in animal studies, like those involving Wistar rats, as sex may influence physiological responses and the outcomes of experimental manipulations applicable to human health contexts.

16) Rules:
'Rules' denote established guidelines or principles that dictate the conduct of research. These are crucial in ensuring ethical standards, reproducibility, and scientific integrity within studies, thereby validating results and maintaining the credibility of scientific findings for broader implications in health and medicine.

17) Accumulation (Accumulating, Accumulate):
'Accumulation' refers to the gradual gathering of substances, like lipids in liver cells. In research concerning liver diseases, understanding how substances accumulate aids in elucidating mechanisms of disease progression, aiding in the development of therapies aimed at ameliorating or preventing such pathological changes.

18) Surface:
'Surface' denotes the outermost layer of an object or system. In pharmacological studies, the surface properties of plant-derived compounds may influence their bioavailability, reactivity, and interaction with biological systems, affecting how effectively they can be utilized for therapeutic purposes.

19) Antibiotic (Antibacterial):
'Antibacterial' relates to substances capable of inhibiting bacterial growth or killing bacteria. Acknowledging antibacterial properties in phytochemicals reveals their potential application in the development of natural antimicrobial agents, promoting public health and addressing resistance issues associated with traditional antibiotics.

20) Observation:
'Observation' signifies the act of monitoring or witnessing phenomena during research. In scientific studies, rigorous observation methods contribute to data collection, ensuring the integrity and accuracy of findings which subsequently influence conclusions drawn regarding treatments or interventions in medical research.

21) Knowledge:
'Knowledge' encompasses information, understanding, and skills acquired through experience or education. In scientific research, expanding knowledge is fundamental for advancing medical insights, guiding innovative therapies, and enriching community understanding of health practices and disease management strategies.

22) Adhikarin (Adhikari):
'Adhikari' is likely a reference to an author or researcher involved in the study. Recognition of contributors is essential in academia, as it highlights the collaborative nature of scientific research and provides context for the credibility and authority behind the findings presented.

23) Shyamala (Syamala):
'Syamala' appears to be linked to an author in the referenced research. Acknowledging individual contributions in research literature is critical for maintaining transparency about the sources of knowledge, fostering accountability, and providing proper attribution for scientific advancements.

24) Krishna (Krsna):
'Krishna' is another name likely identifying an author or researcher involved in the study. Explicitly identifying contributors not only credits their efforts but also helps readers trace and assess the contributions made by various researchers towards advancing scientific knowledge in the field.

25) Camara (Camará):
'Camara' may also refer to an individual, perhaps an author or research contributor. Recognizing those who have made significant efforts in research helps cement their roles in the academic community, ensuring appreciation for their contributions to science and the advancement of knowledge.

26) Forest:
'Forest' refers to a large area covered chiefly with trees and undergrowth. In the context of plant research, understanding the ecological origins of plants like Gardenia ternifolia emphasizes the diversity in phytochemical compounds that are vital for pharmacological studies and applications in traditional medicine.

27) Family:
'Family' in biological taxonomy is a rank in the classification of organisms. Discussing plant families, like the Rubiaceae family for Gardenia ternifolia, is significant as it correlates shared traits and chemical properties among relatives, informing researchers about potential health benefits and therapeutic applications.

28) Ghana:
'Ghana' is a country in West Africa, where many traditional medicinal practices utilize local flora. In relation to pharmacological research, recognizing geographic origins of plant materials enriches understanding of their ethnopharmacological uses and implications for developing region-specific treatments.

29) Karou:
'Karou' likely refers to an author or contributor relevant to this study. Naming contributors not only acknowledges their efforts but also assists readers in evaluating the academic and scientific backgrounds of individuals behind the presented findings, establishing credibility and authority in research.

30) Blood:
'Blood' is the bodily fluid that circulates in the cardiovascular system, delivering essential substances to cells and removing waste products. In medical research, blood analysis is key for understanding various conditions, diagnosing diseases, and evaluating the physiological impacts of treatments or interventions.

31) Bile:
'Bile' is a digestive fluid produced by the liver essential for the emulsification and absorption of fats. In studies related to liver health, the bile’s function highlights the interplay between liver function and overall metabolic processes, informing potential targets for therapeutic interventions.

32) Diet:
'Diet' encompasses the pattern of food consumption contributing to overall health. The relevance of diet in this study emphasizes how ingestion of specific foods, particularly those containing phytochemicals, can influence health outcomes related to liver diseases, framing dietary interventions as potential therapeutic strategies.

33) Post:
'Post' typically denotes a subsequent action or condition following an event. In the context of scientific practice, it may relate to post-experimental evaluations, analyses, or communications that detail findings, contribute to understanding, and drive discussions on implications for future research and methodologies.

34) Drug:
'Drug' refers to a substance used to diagnose, cure, treat, or prevent disease. In pharmacological studies, identifying the effects and mechanisms of plant extracts as potential drugs emphasizes the importance of natural compounds in developing therapeutic options for managing various health conditions.

35) Peer review:
'Peer review' is a process where experts evaluate each other’s work for quality and credibility before publication. This essential aspect of scientific communication ensures that studies meet rigorous standards and provides assurance in the validity of findings presented to the academic and clinical communities.

36) Performance:
'Performance' generally refers to the execution or accomplishment of tasks. Within scientific research, performance can pertain to the effectiveness of treatments or interventions assessed during studies, influencing conclusions regarding their applicability and generally driving improvements in therapeutic strategies.

37) Discussion:
'Discussion' designates a section in research where findings are interpreted in context with existing literature. It enables researchers to articulate significance, propose theories, and direct future research avenues, facilitating the accumulation of understanding within the scientific community.

38) Science (Scientific):
'Science' denotes the systematic pursuit of knowledge via observation and experimentation. Emphasizing its role in discovering and validating new treatments and health interventions reinforces the significance of scientific research in improving human health and addressing worldwide health challenges.

39) Medicine:
'Medicine' encompasses the field dedicated to the science and practice of health care, including the prevention and treatment of diseases. Recognizing the connection between medicinal practices and research underlines the importance of discovering new therapies based on scientific inquiry and traditional knowledge.

40) Language:
'Language' denotes a system of communication. In scholarly contexts, it is essential for conveying complex ideas, facilitating collaboration, and disseminating research findings to diverse audiences, thereby fostering global academic engagement and understanding through shared knowledge and terminologies.

41) Village:
'Village' refers to a small settlement, often rural, where traditional knowledge regarding medicinal plants and practices can flourish. This highlights the importance of community-based knowledge systems in understanding natural remedies and their applications in health care settings, particularly in ethnopharmacological research.

42) Leprosy:
'Leprosy' is a bacterial infection causing severe skin, nerve, and limb damage. Discussing leprosy in the context of medicinal plants underscores the role of traditional herbal remedies in treating chronic conditions, emphasizing the need to explore plant-based therapies for historical diseases.

43) Species:
'Species' refers to a group of organisms capable of interbreeding. In biological and medical research, understanding species variations aids in selecting appropriate model organisms for studies, particularly for compound efficacy and safety evaluations in drug development.

44) India:
'India' is a country rich in biodiversity and traditional medicine practices. Recognizing its contributions to ethnopharmacological advancements highlights the relevance of Indian medicinal systems in providing insights into plant-based therapies, influencing global research on natural products for health management.

45) Glass:
'Glass' indicates a material often used for containers in laboratory settings. Its relevance in scientific studies lies in the function of safely storing and handling substances, ensuring contamination-free environments critical for accurate experimental outcomes, primarily affecting the integrity of research findings.

46) Ivory:
'Ivory' often references a material derived from elephant tusks; however, in a scientific context, it might relate to regions, such as the Ivory Coast. This highlights the significance of geographical influences on biodiversity and ethnobotany, contributing to a better understanding of local medicinal practices.

47) Fever:
'Fever' is a common sign of infection or illness where body temperature rises. Discussing fever demonstrates the need for effective treatments, including herbal remedies; thus, acknowledging the role of traditional medicine in managing clinical symptoms and guiding health interventions in various cultural contexts.

48) House:
'House' signifies a dwelling or facility where people live. In healthcare discussions, understanding the settings for treatment or herbal practices emphasizes cultural context importance, demonstrating how community environments influence health behaviors, access to remedies, and overall health outcomes.

49) Mango:
'Mango' refers to a tropical fruit known for its nutritional and health benefits. In herbal medicine, acknowledging various fruits like mango can underscore the utilization of food in promoting health, reinforcing the need for integrating dietary elements in treating conditions, particularly liver diseases.

50) Cina:
'China' is a country with a rich history of traditional medicine and diverse flora. Acknowledging its contributions emphasizes the significance of Chinese herbal practices and their influence on global pharmacological research, particularly concerning natural compounds and their health applications.

51) Henan:
'Henan' refers to a province in China, often associated with agriculture and rich cultural heritage. Its mention in research might highlight local plant sources and the significance of region-specific ethnopharmacological practices, aiding in the discovery and understanding of therapeutic compounds derived from native plants.

52) Fish:
'Fish' refers to aquatic animals often consumed in various diets, highlighting the nutritional aspects of diet. Recognizing the role of fish as a food source underscores its contributions to health and diet-related studies focusing on liver function and associated diseases.

53) Hand:
'Hand' represents a body part involved in manipulation and interaction. In research, mention of 'hand' can symbolize human participation in studies or cultural practices involving herbal medicine, emphasizing the role of human action in health care delivery and traditional practices.

54) Salt (Salty):
'Salt' is a mineral important for dietary needs and various physiological functions. In medical research, discussing salt emphasizes its relevance within diet, potential impacts on health, and the need for balance in nutrition to manage and prevent conditions affecting liver health and overall well-being.

55) Pir:
'Peer' denotes an individual of similar standing, especially within an academic or professional context. The term 'peer' highlights the collaborative nature of research, reliance on expert validation in study findings, and emphasizes the importance of community in advancing scientific knowledge.

Other Science Concepts:

[back to top]

Discover the significance of concepts within the article: ‘Protective effects of Gardenia ternifolia extracts on liver disease.’. Further sources in the context of Science might help you critically compare this page with similair documents:

Corticosteroids, High performance liquid chromatography, Phytochemical screening, Phytochemical analysis, Oxidative stress, Alcoholic liver disease, Hepatoprotective effect, Histological examination, Total cholesterol level, Nutritional therapy, Silymarin, Serum triglyceride level, Alanine Aminotransferase, Aspartate Aminotransferase, Aqueous extract preparation, Biochemical parameter, Male wistar albino rats, Wistar albino rat.

Like what you read? Consider supporting this website: