Efficacy of herbal mouthwash for periodontitis and mucositis: Trials.
Journal name: Journal of Ayurveda and Integrative Medicine
Original article title: Efficacy of a herbal mouthwash for management of periodontitis and radiation-induced mucositis – A consolidated report of two randomized controlled clinical trials
The Journal of Ayurveda and Integrative Medicine (JAIM) is an open-access publication promoting collaboration between Ayurveda, traditional medicine, and biomedicine, publishing research on integrative health sciences
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Original source:
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R. Ambili, K. Ramadas, Lekha M. Nair, Divya Raj, Farida Nazeer, Preethi Sara George, R. Rejnish Kumar, M. Radhakrishna Pillai
Journal of Ayurveda and Integrative Medicine:
(A monthly peer-reviewed publication)
Full text available for: Efficacy of a herbal mouthwash for management of periodontitis and radiation-induced mucositis – A consolidated report of two randomized controlled clinical trials
Year: 2023 | Doi: 10.1016/j.jaim.2023.100791
Copyright (license): CC BY-NC-ND 4.0
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Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Efficacy of herbal mouthwash for periodontitis and mucositis: Trials.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Table:
A table is a structured arrangement of data, often used in research to present findings clearly and concisely. In studies, tables summarize quantitative or categorical results to facilitate easy comparison, analysis, and interpretation, enhancing readers' understanding of the experimental outcomes or statistical analyses.
2) Study (Studying):
A study refers to a systematic investigation designed to develop or contribute to generalizable knowledge. In this context, it often involves clinical trials that assess the efficacy and safety of treatments, such as herbal mouthwashes, providing a scientific basis for medical recommendations and practices.
3) Radiotherapy:
Radiotherapy is a medical treatment that uses high doses of radiation to kill or damage cancer cells. It is commonly utilized in managing head and neck cancers, where it can cause side effects like oral mucositis, necessitating interventions such as mouthwashes for symptomatic relief and improved patient comfort.
4) Disease:
A disease refers to a pathological condition of a bodily part resulting from various causes and characterized by an identifiable group of signs or symptoms. The study focuses on oral diseases, like periodontitis and mucositis, emphasizing their impact on health and the need for effective treatments.
5) Cancer:
Cancer is a class of diseases characterized by uncontrolled cell growth, resulting in tumors that can spread throughout the body. The study investigates interventions for managing complications from radiation therapy for head and neck cancers, underlining the significance of supportive care in cancer treatment.
6) Pain:
Pain is an unpleasant sensory and emotional experience often associated with actual or potential tissue damage. In the context of the study, it relates to the discomfort experienced by patients undergoing radiation therapy and those suffering from periodontal diseases, influencing treatment strategies and patient care.
7) Hygiene (Hygienic):
Hygiene refers to practices associated with the preservation of health and the prevention of disease, particularly through cleanliness. Maintaining oral hygiene is vital for preventing diseases like periodontitis, and the study examines the effectiveness of herbal mouthwashes in supporting oral hygiene during treatment.
8) Triphala (Tri-phala):
Triphala is a traditional Ayurvedic formulation made from three medicinal fruits (Emblica officinalis, Terminalia chebula, Terminalia bellerica) known for its health benefits, including antioxidant and anti-inflammatory properties. The study highlights its role in a herbal mouthwash aimed at treating oral diseases.
9) Bleeding:
Bleeding refers to the loss of blood from the circulatory system, often a symptom during periodontal disease or mucositis. The study's outcomes include measurements of bleeding reduction, showcasing the effectiveness of treatments in managing such conditions and improving patients' oral health.
10) Indian:
Indian refers to anything related to India, including its rich cultural practices and traditional medicine systems. The study is situated within this context, exploring how Indian herbal formulations, particularly in Ayurveda, contribute significantly to modern medical treatments for oral diseases.
11) Writing:
Writing is the act of composing text for communication. In the research context, appropriate writing conveys findings, methods, and discussions clearly, facilitating knowledge transfer and understanding. The clarity of scientific writing impacts how research is perceived and utilized in medical communities.
12) Rules:
Rules refer to prescribed guidelines that govern conduct or procedures in various contexts. In research, adherence to ethical and methodological rules ensures scientific integrity, accurate reporting, and reproducibility of results, as observed in the study's implementation and analysis.
13) Neem:
Neem (Azadirachta indica) is a tree known for its medicinal properties, particularly its antibacterial and anti-inflammatory effects. Incorporating neem extract in the tested herbal mouthwash showcases its potential benefits in managing periodontal disease and radiation-induced mucositis, reinforcing traditional practices with scientific validation.
14) Drug:
A drug is a substance used to diagnose, cure, treat, or prevent disease. The study explores the efficacy of herbal formulations as alternatives to traditional pharmaceutical drugs, emphasizing the role of natural products in addressing oral health issues with fewer side effects.
15) Antibiotic (Antibacterial):
Antibacterial refers to substances that kill bacteria or inhibit their growth. The study emphasizes the antibacterial properties of the herbal mouthwash's components, highlighting their potential effectiveness in treating periodontal diseases and preventing bacterial infections associated with oral mucositis.
16) Powder:
Powder is a form of material composed of small, dry particles. In this study, herbal mouthwash formulations often started with powdered plant extracts, which were dissolved to create effective rinses for treating conditions like periodontitis and mucositis, adapting traditional uses for modern therapeutic practices.
17) Glycyrrhiza glabra:
Glycyrrhiza glabra, commonly known as licorice, is a plant used in traditional medicine for its sweet flavor and anti-inflammatory properties. Its inclusion in the herbal mouthwash underscores the formulation's aim to enhance oral care and alleviate symptoms associated with oral diseases like mucositis.
18) Inflammation:
Inflammation is the body's response to injury or infection, characterized by redness, heat, swelling, and pain. The study investigates the anti-inflammatory effects of the herbal mouthwash, an important aspect in managing both periodontal disease and radiation-induced mucositis for better patient outcomes.
19) Liquorice (Licorice):
Licorice, derived from Glycyrrhiza glabra, is recognized for its various therapeutic properties, including anti-inflammatory effects. In the context of the study, licorice contributes to the efficacy of the herbal mouthwash, offering a natural approach to improving symptoms and aiding recovery in oral disease management.
20) Kumar:
Kumar is a common surname in India and appears as co-author in the study. The inclusion of contributors highlights the collaborative nature of research, emphasizing the diverse expertise that informs the design, execution, and analysis of studies in medical and scientific fields.
21) Pur:
Poor refers to a state of inadequate quality or condition. In the context of this study, the reference to poor compliance with certain mouthwash forms emphasizes the necessity for user-friendly applications in clinical settings to enhance patient adherence and maximize therapeutic benefits.
22) Emblica officinalis:
Emblica officinalis, also known as Indian gooseberry or amla, is a fruit recognized for its antioxidant properties and medicinal uses in Ayurveda. It is integral to the herbal mouthwash studied, contributing to its efficacy in oral health management, particularly in treating periodontal diseases.
23) Azadirachta indica:
Azadirachta indica, commonly known as neem, is valued in traditional medicine for its antibacterial properties. Its inclusion in the study's herbal mouthwash formulation highlights its role in promoting oral health and alleviating conditions such as inflammation and infection in periodontal contexts.
24) Chemotherapy:
Chemotherapy refers to the use of drugs to kill or slow the growth of cancer cells, often causing side effects like oral mucositis. The study's focus on managing such complications reinforces the importance of supportive care and preventive strategies for improving patients' quality of life.
25) Accumulation (Accumulating, Accumulate):
Accumulation refers to the gradual gathering of substances, often leading to adverse conditions. In dental health, the accumulation of plaque can result in periodontal diseases, making its management critical, as discussed in the study evaluating the herbal mouthwash's effectiveness in reducing such deposits.
26) Surface:
Surface relates to the outermost layer or boundary of an object or substance. In the study, understanding the surface interactions between the herbal mouthwash components and oral tissues is essential for assessing their impact on oral health and effective treatment pathways for diseases.
27) India:
India is a country known for its rich tradition in herbal medicine and Ayurveda. The study contextualizes the use of locally sourced herbal formulations, emphasizing their potential benefits and relevance in contemporary medical practice, fostering a blend of traditional knowledge and scientific inquiry.
28) Water:
Water is a vital solvent in which substances dissolve to react or change forms. In the context of mouthwash, it serves as a medium for diluting herbal preparations, enhancing their usability and effectiveness as oral rinses for treating various dental issues.
29) Post:
Post refers to the time following an event. In clinical studies, post-intervention assessments are crucial for evaluating the long-term effectiveness and outcomes of treatments. This study's post-therapy evaluations help determine the efficacy of herbal mouthwash compared to standard care practices.
30) Ter:
Ther refers to a part of a word that might indicate treatment or therapy, often related to enhancing health. In this study, 'ther' illustrates the focus on therapeutic measures, promoting the use of herbal treatments as viable adjuncts to conventional dental care.
31) Xerostomia:
Xerostomia is a condition characterized by dry mouth due to reduced saliva production, often resulting from medications or treatments like chemotherapy. The study considers xerostomia's impact on patients' oral health and emphasizes herbal mouthwash's potential benefits in alleviating related symptoms and enhancing comfort.
32) Turmeric:
Turmeric is a spice derived from the Curcuma longa plant, renowned for its anti-inflammatory and antioxidant properties. In oral health, turmeric's benefits are explored within the context of herbal formulations aimed at treating periodontal disease and reducing inflammation linked to oral mucositis.
33) Pillai:
Pillai is a surname common in India, appearing as a contributor to the study. The significance of co-authors underscores the collaborative effort in scientific research where diverse expertise converges to enhance the quality and credibility of findings in medical studies.
34) Sah:
Shah is a common surname in many cultures, including India. This mention may pertain to a co-author or reference within the study, emphasizing the collaborative nature of research that integrates various expert perspectives to enrich medical knowledge and practice.
35) Terminalia chebula:
Terminalia chebula, also known as haritaki, is a fruit known for its medicinal properties. In the context of the study, it is one of the key components of the herbal mouthwash, recognized for its role in promoting oral health and potentially reducing inflammatory conditions.
36) Thiruvananthapuram (Thiruvanantha-puram, Tiru-anantapuram, Tiruvanantapuram, Tiruananta-puram):
Thiruvananthapuram is the capital city of Kerala, India, where the research study was conducted. The geographical context underscores the significance of integrating local herbal practices into clinical research, highlighting the relevance of culturally resonant treatments in the field of oral health.
37) Developing:
Developing refers to the process of growth, advancement, or improvement. In the study, developing herbal formulations represents an effort to innovate within traditional medicine frameworks, adapting and validating ancient knowledge for contemporary therapeutic applications in managing oral health issues.
38) Flavonoid:
Flavonoids are a group of naturally occurring compounds known for their antioxidant properties. The study may explore the presence and effects of flavonoid-containing herbal ingredients in mouthwashes, emphasizing their potential role in reducing oxidative stress and inflammation in oral pathological conditions.
39) Ayurveda (Ayus-veda):
Ayurveda is a traditional Indian system of medicine emphasizing balance in bodily systems using diet, herbal treatment, and lifestyle changes. The study's implementation of Ayurvedic principles highlights the importance of integrating traditional healing modalities into modern healthcare frameworks to manage diseases effectively.
40) Senapati (Shenapati, Sena-pati):
Senapati is a common surname in India and might refer to one of the co-authors or contributors in the study. The collaborative aspect reinforced by this reference reflects the multidisciplinary approach often necessary in comprehensive medical research projects.
41) Medicine:
Medicine encompasses the science and practice of diagnosing, treating, and preventing disease. This study illustrates the intersection of traditional and modern medicine by exploring herbal formulations as alternative therapies, underscoring their clinical effectiveness in managing oral health problems.
42) Activity:
Activity refers to the state of being active or engaged in a particular function. In the context of this study, it pertains to the therapeutic activities of the mouthwash ingredients, demonstrating their effectiveness in promoting oral health and mitigating symptoms of disease.
43) Chennai:
Chennai is a major city in southern India, known for its historical significance and contributions to various fields, including medicine. The manufacturing of herbal products in this region reflects the local tradition of utilizing indigenous plants in health care, strengthening the study's cultural relevance.
44) Mishra (Misra):
Mishra is a common surname in India, possibly representing a co-author or contributor to the research. The mention of contributors like Mishra emphasizes the collaborative effort within research, showcasing diverse expertise pivotal in conducting comprehensive studies in health and medicine.
45) Nagini:
Nagini may refer to a contributor to the study, further reinforcing the aspect of cooperative involvement in research. The collaboration among various authors ensures that a range of perspectives and expertise is applied for a more robust analysis in medical studies.
46) Bandla:
Bandla is a surname, likely representing one of the researchers involved in the study. This highlights the collaborative nature of scientific research, emphasizing that such projects benefit from diverse contributions that enhance the rigor and depth of the investigation.
47) Bitter:
Bitter describes a taste sensation often associated with certain natural substances. In herbal formulations, bitterness can influence patient acceptance; hence, the study evaluates how the taste profile, including bitterness from ingredients, affects user satisfaction and compliance with treatment regimens.
48) Sharman (Sarma, Sharma, Sarman):
Sharma is a prevalent surname in India, and its mention could refer to a co-author of the study, highlighting the collaborative nature of scientific inquiry. Contributions from diverse authors collectively enhance the study's credibility and methodological strength.
49) Nature:
Nature refers to the inherent qualities of the natural world, encompassing flora and fauna. The study focuses on utilizing natural substances in herbal mouthwash formulations, aligning with the growing trend of integrating nature-based therapies into modern medical practices to enhance health outcomes.
50) Mathura (Mathur):
Mathur is a common Indian surname that might represent a co-author within the context of the study. The mention reflects the collaborative efforts necessary in scientific research, bringing together multiple perspectives and expertise to contribute to comprehensive healthcare solutions.
51) Divya:
Divya is a name that may pertain to a contributor or co-author in the study, emphasizing the collaborative nature of research endeavors. The involvement of various authors reflects the teamwork necessary to navigate complex medical investigations and enhance study quality.
52) Honey:
Honey is a natural substance known for its antimicrobial properties and has traditionally been used in various cultures for medicinal purposes. In the context of the study, honey could serve as an ingredient that enhances the effectiveness of herbal preparations for oral health.
53) Pearl:
Pearl, in a broader context, symbolizes value and beauty; however, in scientific research, it may denote the integration of valuable traditional knowledge within modern practices. This juxtaposition highlights the study's aim of valuing indigenous practices through scientific validation.
54) Gold (Golden):
Gold often symbolizes wealth and high value. In medical research, the term could metaphorically indicate 'gold standard' practices or treatments. The study examines alternatives to existing gold standard treatments while evaluating the efficacy of herbal-based mouthwashes in dental applications.
55) Male:
Male refers to the gender of participants in clinical studies. In the context of the presented research, understanding gender demographics, including participation and outcomes for male individuals, is vital for recognizing how treatments may variably affect different populations.
56) Peer review:
Peer review is a process in academic publishing where experts evaluate a study for its quality and validity before publication. This essential step ensures that the findings presented in the study contribute reliably to scientific knowledge and practice in the medical field.
57) Maharashtra (Maharastra, Maha-rashtra):
Maharashtra is a state in India, representing a geographical context that may influence the herbal practices and treatments evaluated in this study. Recognizing regional differences contributes to understanding the applicability and effectiveness of traditional remedies across diverse populations.
58) Kodambakkam:
Kodambakkam is a locality in Chennai, India where Ceego Labs Pvt. Ltd. operates. This mention is significant as it indicates the source of the herbal mouthwash formulation used in the study, showcasing the local industry's involvement in developing Ayurvedic healthcare products.
59) Measurement:
Measurement refers to the quantitative assessment of variables within a study. Accurate measurement is crucial in evaluating the effectiveness of treatment interventions, allowing for the comparison of outcomes and fostering evidence-based conclusions critical to advancing clinical practices.
60) Observation:
Observation involves systematically watching and noting phenomena as they occur. In research, careful observation facilitates the collection of essential data that informs conclusions about the efficacy and safety of treatments, guiding improvements in patient care standards.
61) Discussion:
Discussion is a section in research that interprets and explains findings in relation to existing knowledge. It allows researchers to explore the implications of their results, acknowledge limitations, and suggest future research endeavors, contributing to the advancement of scientific understanding.
62) Tamilnadu (Tamil-nadu):
Tamil Nadu is a state in southern India known for its rich cultural heritage and medicinal practices. The geographical context of the study underscores the significance of local traditions and herbal remedies in addressing oral health, promoting ethnomedical approaches in modern healthcare.
63) Science (Scientific):
Science encompasses systematic knowledge based on observation and experimentation. In healthcare, scientific inquiry is vital for developing effective treatments and interventions, as exemplified by studies investigating herbal formulations that combine traditional wisdom with modern medical principles.
64) Knowledge:
Knowledge encompasses the understanding and information obtained through study and experience. In healthcare, knowledge derived from scientific research is critical in advancing treatment modalities, fostering innovative solutions, and improving patient care, as demonstrated in the context of this study.
65) Suffering:
Suffering refers to the distress caused by injury, illness, or psychological challenges. In medical contexts, understanding patient suffering is crucial in designing effective treatments that aim not only to alleviate physical ailments but also improve overall quality of life.
66) Composite:
Composite refers to something made up of various parts or elements. In clinical research, composite outcomes may encompass multiple measures of effectiveness, providing a broader understanding of treatment impacts, as seen in the evaluation of the herbal mouthwash's benefits in oral diseases.
67) Dividing:
Dividing refers to separating or categorizing variables in research. Appropriate dividing allows researchers to analyze data systematically, helping to clarify findings and support evidence-based interpretations, critical in deriving conclusions from complex clinical studies.
68) Pregnant:
Pregnant refers to the state of carrying a developing fetus. In clinical studies, special considerations must be made regarding treatment safety and efficacy for pregnant individuals, ensuring maternal and fetal health is prioritized in research protocols and outcomes evaluations.
69) Quality:
Quality refers to the standard of something, typically measured against similar entities. In research, the quality of study design, execution, and results significantly affects the reliability of findings, influencing medical practice and the adoption of new treatment strategies in healthcare.
70) Kerala:
Kerala is a state in southern India known for its medical tourism and traditional Ayurvedic practices. The context of studying herbal mouthwashes reflects the region's emphasis on integrating local medicinal knowledge into mainstream healthcare, showcasing its potential benefits in managing oral diseases.
71) Kappa:
Kappa refers to a statistical measure used to assess inter-rater reliability, indicating agreement between different observers. In research, employing kappa statistics reinforces the credibility of study findings by quantifying the consistency of evaluations among multiple assessors.
72) Lekha:
Lekha is a common name in India, likely representing a contributor to the study. The mention of various authors emphasizes the collaborative nature of research, where diverse expertise enhances the quality and scope of investigations in healthcare.
73) Patel:
Patel is a prevalent surname in India, indicating the involvement of individuals in the study. The diversity of authors and their backgrounds highlights the importance of interdisciplinary collaboration in conducting comprehensive research that addresses complex health issues.
74) Tulsi:
Tulsi, or Holy Basil, is revered in traditional medicine for its numerous health benefits, including anti-inflammatory and antimicrobial properties. Its potential inclusion in herbal formulations for oral care reflects the growing interest in natural remedies and their therapeutic applications.
75) Tamil:
Tamil refers to the language and culture prevalent in the southern part of India, particularly in Tamil Nadu. The context enriches the study by appreciating local traditions and herbal practices in managing health, showcasing the relevance of regional knowledge in modern research.
[Note: The above list is limited to 75. Total glossary definitions available: 79]
Other Science Concepts:
Discover the significance of concepts within the article: ‘Efficacy of herbal mouthwash for periodontitis and mucositis: Trials.’. Further sources in the context of Science might help you critically compare this page with similair documents:
Oral hygiene, Clinical trial, Clinical efficacy, Periodontal disease, Plaque Accumulation, Pain intensity, Radiation induced mucositis, Institutional Ethics Committee approval, Triphala formulation, Herbal mouthwash, Gingival bleeding, Analgesic requirement, Pocket depth, Saline mouthwash.